Issue 1/2022
Content (629 Articles)
Bilirubin ameliorates murine atherosclerosis through inhibiting cholesterol synthesis and reshaping the immune system
Guanmei Wen, Leyi Yao, Yali Hao, Jinheng Wang, Jinbao Liu
Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Wai Hoong Chang, Stefanie H. Mueller, Sheng-Chia Chung, Graham R. Foster, Alvina G. Lai
Circulating exosomal hsa_circRNA_0039480 is highly expressed in gestational diabetes mellitus and may be served as a biomarker for early diagnosis of GDM
Bao Jiang, Junfeng Zhang, Xiubin Sun, Chunyan Yang, Guanghui Cheng, Mengru Xu, Siyuan Li, Lina Wang
The role of Exosomal miRNAs in cancer
Chuanyun Li, Tong Zhou, Jing Chen, Rong Li, Huan Chen, Shumin Luo, Dexi Chen, Cao Cai, Weihua Li
Increased expression of six-large extracellular vesicle-derived miRNAs signature for nonvalvular atrial fibrillation
Panjaree Siwaponanan, Pontawee Kaewkumdee, Wilasinee Phromawan, Suthipol Udompunturak, Nusara Chomanee, Kamol Udol, Kovit Pattanapanyasat, Rungroj Krittayaphong
Long noncoding RNA NEAT1 promotes cardiac fibrosis in heart failure through increased recruitment of EZH2 to the Smad7 promoter region
Zhuowang Ge, Chengye Yin, Yingze Li, Ding Tian, Yin Xiang, Qianhui Li, Yong Tang, Yachen Zhang
Diabetes, hypertension, and cardiovascular disease development
Fu-Shun Yen, James Cheng-Chung Wei, Lu-Ting Chiu, Chih-Cheng Hsu, Chii-Min Hwu
Dysbiosis of vaginal microbiota associated with persistent high-risk human papilloma virus infection
Ling Mei, Tao Wang, Yueyue Chen, Dongmei Wei, Yueting Zhang, Tao Cui, Jian Meng, Xiaoli Zhang, Yuqing Liu, Lisha Ding, Xiaoyu Niu
Clinical efficiency of simultaneous CNV-seq and whole-exome sequencing for testing fetal structural anomalies
Xinlin Chen, Yulin Jiang, Ruiguo Chen, Qingwei Qi, Xiujuan Zhang, Sheng Zhao, Chaoshi Liu, Weiyun Wang, Yuezhen Li, Guoqiang Sun, Jieping Song, Hui Huang, Chen Cheng, Jianguang Zhang, Longxian Cheng, Juntao Liu
GM-CSF impairs erythropoiesis by disrupting erythroblastic island formation via macrophages
Weijie Cao, Wenjuan Fan, Fang Wang, Yinyin Zhang, Guanghua Wu, Xiaojing Shi, Jian xiang Shi, Fengcai Gao, Meimei Yan, Rong Guo, Yingmei Li, Wei Li, Chunyan Du, Zhongxing Jiang
microRNA-155-3p delivered by M2 macrophages-derived exosomes enhances the progression of medulloblastoma through regulation of WDR82
Li Song, Bin Luan, Qingrong Xu, Ruihe Shi, Xiufang Wang
Process development and validation of expanded regulatory T cells for prospective applications: an example of manufacturing a personalized advanced therapy medicinal product
Cristiana Lavazza, Silvia Budelli, Elisa Montelatici, Mariele Viganò, Francesca Ulbar, Lucia Catani, Marta Giulia Cannone, Sara Savelli, Elisa Groppelli, Lorenza Lazzari, Roberto M. Lemoli, Matteo Cescon, Gaetano La Manna, Rosaria Giordano, Tiziana Montemurro
Integrated weighted gene coexpression network analysis identifies Frizzled 2 (FZD2) as a key gene in invasive malignant pleomorphic adenoma
Zhenyuan Han, Huiping Ren, Jingjing Sun, Lihui Jin, Qin Wang, Chuanbin Guo, Zhen Tian
Bacterial infections exacerbate myeloma bone disease
Rui Liu, Yuping Zhong, Rui Chen, Shiyi Chen, Yazhu Huang, Huan Liu
CTPS1 promotes malignant progression of triple-negative breast cancer with transcriptional activation by YBX1
Yuxiang Lin, Jie Zhang, Yan Li, Wenhui Guo, Lili Chen, Minyan Chen, Xiaobin Chen, Wenzhe Zhang, Xuan Jin, Meichen Jiang, Han Xiao, Chuan Wang, Chuangui Song, Fangmeng Fu
Identification of COPA as a potential prognostic biomarker and pharmacological intervention target of cervical cancer by quantitative proteomics and experimental verification
Huiqiong Bao, Xiaobin Li, Zhixing Cao, Zhihong Huang, Li Chen, Mingbing Wang, Jiali Hu, Wenting Li, Hongwei Sun, Xue Jiang, Ping Mei, Huawen Li, Ligong Lu, Meixiao Zhan
FOXA1 can be modulated by HDAC3 in the progression of epithelial ovarian carcinoma
Tong Lou, Chongdong Liu, Hong Qu, Zhiqiang Zhang, Shuzhen Wang, Huiyu Zhuang
MiR-30c-5p loss-induced PELI1 accumulation regulates cell proliferation and migration via activating PI3K/AKT pathway in papillary thyroid carcinoma
Tingting Zheng, Youxing Zhou, Xiaowei Xu, Xin Qi, Jiameng Liu, Yanan Pu, Shan Zhang, Xuerong Gao, Xinkai Luo, Mei Li, Xuefeng Wang, Liyang Dong, Ying Wang, Chaoming Mao
VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy
Cheng Cheng, Lan Weiss, Henri Leinonen, Alyaa Shmara, Hong Z. Yin, Timothy Ton, Annie Do, Jonathan Lee, Lac Ta, Eshanee Mohanty, Jesse Vargas, John Weiss, Krzysztof Palczewski, Virginia Kimonis
Different decay of antibody response and VOC sensitivity in naïve and previously infected subjects at 15 weeks following vaccination with BNT162b2
Gabriel Siracusano, Alessandra Ruggiero, Zeno Bisoffi, Chiara Piubelli, Luca Dalle Carbonare, Maria Teresa Valenti, Martin Mayora-Neto, Nigel Temperton, Lucia Lopalco, Donato Zipeto
VLCKD: a real time safety study in obesity
Luigi Barrea, Ludovica Verde, Claudia Vetrani, Francesca Marino, Sara Aprano, Silvia Savastano, Annamaria Colao, Giovanna Muscogiuri
Correction to: Metabolic analysis of early nonalcoholic fatty liver disease in humans using liquid chromatography–mass spectrometry
Cheng Hu, Tao Wang, Xiaoyu Zhuang, Qiaoli Sun, Xiaochun Wang, Hui Lin, Mingli Feng, Jiaqi Zhang, Qin Cao, Yuanye Jiang
Correction to: An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Klaus J. Wirth, Carmen Scheibenbogen, Friedemann Paul
First evidence of long-term effects of transcranial pulse stimulation (TPS) on the human brain
Eva Matt, Lisa Kaindl, Saskia Tenk, Anicca Egger, Teodora Kolarova, Nejla Karahasanović, Ahmad Amini, Andreas Arslan, Kardelen Sariçiçek, Alexandra Weber, Roland Beisteiner
Ground truth labels challenge the validity of sepsis consensus definitions in critical illness
Holger A. Lindner, Shigehiko Schamoni, Thomas Kirschning, Corinna Worm, Bianka Hahn, Franz-Simon Centner, Jochen J. Schoettler, Michael Hagmann, Jörg Krebs, Dennis Mangold, Stephanie Nitsch, Stefan Riezler, Manfred Thiel, Verena Schneider-Lindner
GDF11 alleviates neointimal hyperplasia in a rat model of artery injury by regulating endothelial NLRP3 inflammasome activation and rapid re-endothelialization
Lei Li, Yan Gao, Zhenchuan Liu, Chenglai Dong, Wenli Wang, Kaiqin Wu, Shaorui Gu, Yongxin Zhou
Incidental germline findings during molecular profiling of tumor tissues for precision oncology: molecular survey and methodological obstacles
Alexandra Lebedeva, Yulia Shaykhutdinova, Daria Seriak, Ekaterina Ignatova, Ekaterina Rozhavskaya, Divyasphoorthi Vardhan, Sofia Manicka, Margarita Sharova, Tatiana Grigoreva, Ancha Baranova, Vladislav Mileyko, Maxim Ivanov
Evaluation of exosomal non-coding RNAs in cancer using high-throughput sequencing
Kamran Hosseini, Maryam Ranjbar, Abbas Pirpour Tazehkand, Parina Asgharian, Soheila Montazersaheb, Vahideh Tarhriz, Tohid Ghasemnejad
Development of a radiomics model to diagnose pheochromocytoma preoperatively: a multicenter study with prospective validation
Jianqiu Kong, Junjiong Zheng, Jieying Wu, Shaoxu Wu, Jinhua Cai, Xiayao Diao, Weibin Xie, Xiong Chen, Hao Yu, Lifang Huang, Hongpeng Fang, Xinxiang Fan, Haide Qin, Yong Li, Zhuo Wu, Jian Huang, Tianxin Lin
The effect of omega‑3 fatty acid supplementation on clinical and biochemical parameters of critically ill patients with COVID‑19: a randomized clinical trial
Seyedeh Zoha Safaei Ardestani, Seyedeh Tayebeh Rahideh
Pediococcus pentosaceus CECT 8330 protects DSS-induced colitis and regulates the intestinal microbiota and immune responses in mice
Fang Dong, Fangfei Xiao, Xiaolu Li, Youran Li, Xufei Wang, Guangjun Yu, Ting Zhang, Yizhong Wang
Point-of-care cell therapy manufacturing; it’s not for everyone
David F. Stroncek, Robert P. T. Somerville, Steven L. Highfill
Correction to: Identification and functional analysis of a three-miRNA ceRNA network in hypertrophic scars
Zewei Zhang, Xin Huang, Jiahao Yang, Shuchen Gu, Yixuan Zhao, Yunhan Liu, Yimin Khoong, Shuqi Wang, Shenying Luo, Tao Zan, Guangshuai Li
Heart-specific DNA methylation analysis in plasma for the investigation of myocardial damage
Jie Ren, Lin Jiang, Xiaomeng Liu, Yuhan Liao, Xueyan Zhao, Fuchou Tang, Huimin Yu, Yibing Shao, Jizheng Wang, Lu Wen, Lei Song
RNA-binding proteins in ovarian cancer: a novel avenue of their roles in diagnosis and treatment
Jiangchun Wu, Yong Wu, Qinhao Guo, Simin Wang, Xiaohua Wu
CT-based radiomics nomograms for preoperative prediction of diffuse-type and signet ring cell gastric cancer: a multicenter development and validation cohort
Tao Chen, Jing Wu, Chunhui Cui, Qinglie He, Xunjun Li, Weiqi Liang, Xiaoyue Liu, Tianbao Liu, Xuanhui Zhou, Xifan Zhang, Xiaotian Lei, Wei Xiong, Jiang Yu, Guoxin Li
Identifying CCR5 coreceptor populations permissive for HIV-1 entry and productive infection: implications for in vivo studies
Matthew Weichseldorfer, Yutaka Tagaya, Marvin Reitz, Anthony L. DeVico, Olga S. Latinovic
Autoantigen microarrays reveal myelin basic protein autoantibodies in morphea
Jane L. Zhu, Ricardo T. Paniagua, Henry W. Chen, Stephanie Florez-Pollack, Elaine Kunzler, Noelle Teske, Yevgeniya Byekova Rainwater, Quan-Zhen Li, Gregory A. Hosler, Wenhao Li, Denise M. O. Ramirez, Nancy L. Monson, Heidi T. Jacobe
Good performance of the criteria of American College of Medical Genetics and Genomics/Association for Molecular Pathology in prediction of pathogenicity of genetic variants causing thoracic aortic aneurysms and dissections
Joanna Kinga Ponińska, Zofia Teresa Bilińska, Grażyna Truszkowska, Ewa Michalak, Anna Podgórska, Małgorzata Stępień-Wojno, Przemysław Chmielewski, Anna Lutyńska, Rafał Płoski
Polygenic risk and causal inference of psychiatric comorbidity in inflammatory bowel disease among patients with European ancestry
Yao Li, Charles N. Bernstein, Wei Xu, Pingzhao Hu
NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy
Duojun Qiu, Shan Song, Yuhan Wang, Yawei Bian, Ming Wu, Haijiang Wu, Yonghong Shi, Huijun Duan
Moderate physical activity may not decrease the risk of cardiovascular disease in persistently overweight and obesity adults
Qiuyue Tian, Biyan Wang, Shuohua Chen, Shouling Wu, Youxin Wang
Correction to: Sirtuin 3 deficiency aggravates contrast-induced acute kidney injury
Qinghai Zhang, Xun Liu, Na li, Jihong Zhang, Jianmin Yang, Peili Bu
Downregulation of NEDD4L by EGFR signaling promotes the development of lung adenocarcinoma
Guoyin Li, Zewen Song, Changjing Wu, XiaoYan Li, Liping Zhao, Binghua Tong, Zhenni Guo, Meiqing Sun, Jin Zhao, Huina Zhang, Lintao Jia, Shengqing Li, Lei Wang
Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomes
Shengwei Li, Qian Liu, Haiying Zhou, Hui Lu, Xiaosheng Wang
Demethylation at enhancer upregulates MCM2 and NUP37 expression predicting poor survival in hepatocellular carcinoma patients
Zengwei Tang, Yuan Yang, Wen Chen, Enliang Li, Tingbo Liang
MAL protein suppresses the metastasis and invasion of GC cells by interfering with the phosphorylation of STAT3
Zhijun Geng, Jing Li, Sandang Li, Yueyue Wang, Lele Zhang, Qiuzi Hu, Xinru Wang, Lugen Zuo, Xue Song, Xiaofeng Zhang, Sitang Ge, Jianguo Hu
piRNA-14633 promotes cervical cancer cell malignancy in a METTL14-dependent m6A RNA methylation manner
Qi Xie, Zhen Li, Xiao Luo, Dan Wang, Yao Zhou, Jingge Zhao, Suhua Gao, Yongguang Yang, Wanying Fu, Lingfei Kong, Tingyi Sun
Host miRNAs-microbiota interactions in gastric cancer
Yan Yang, Yingying Huang, Wu Lin, Jin Liu, Xiangliu Chen, Chuanzhi Chen, Xiongfei Yu, Lisong Teng
Single-cell transcriptomic analysis reveals a novel cell state and switching genes during hepatic stellate cell activation in vitro
Hua Wang, Shaoping Zheng, Hongbo Jiang, Xuejia Wang, Fengqin Zhou, Zhihong Weng
The ILEI/LIFR complex induces EMT via the Akt and ERK pathways in renal interstitial fibrosis
Jieqing Zhou, Hong Jiang, Hongkun Jiang, Yan Fan, Jing Zhang, Xiaoxue Ma, Xuewei Yang, Yu Sun, Xing Zhao
An integrative multi-omics analysis based on liquid–liquid phase separation delineates distinct subtypes of lower-grade glioma and identifies a prognostic signature
Jianglin Zheng, Zhipeng Wu, Yue Qiu, Xuan Wang, Xiaobing Jiang
Electrical stimulation of the cochlea for treatment of chronic disabling tinnitus: an open-label trial towards the development of an implantable device
John P. Marinelli, C. Lane Anzalone, Christoph M. Prummer, Gayla L. Poling, Jeffrey P. Staab, Nicole M. Tombers, Christine M. Lohse, Matthew L. Carlson
Liver-specific LINC01146, a promising prognostic indicator, inhibits the malignant phenotype of hepatocellular carcinoma cells both in vitro and in vivo
Xiaoyun Ma, Meile Mo, Chao Tan, Jennifer Hui Juan Tan, Huishen Huang, Bihu Liu, Dongping Huang, Shun Liu, Xiaoyun Zeng, Xiaoqiang Qiu
Circular RNA circCSPP1 promotes the occurrence and development of colon cancer by sponging miR-431 and regulating ROCK1 and ZEB1
Jin Wang, Lei Zhou, Bingxin Chen, Zhuwen Yu, Jianglei Zhang, Zhe Zhang, Chenrui Hu, Yanjin Bai, Xiaokang Ruan, Shengjia Wang, Jun Ouyang, Airong Wu, Xin Zhao
Effects of focus training on heart rate variability in post-stroke fatigue patients
Yao Wang, Gonglian Xiao, Qing Zeng, Mingjun He, Fei Li, Jiaxin Lin, Xun Luo, Yulong Wang
Effects of high-intensity interval training on improving arterial stiffness in Chinese female university students with normal weight obese: a pilot randomized controlled trial
Jingyun Hu, Min Liu, Ruoyu Yang, Liyan Wang, Leichao Liang, Yuanyuan Yang, Shihao Jia, Ruiyi Chen, Qianle Liu, Yu Ren, Lei Zhu, Ming Cai
Combining serum inflammation indexes at baseline and post treatment could predict pathological efficacy to anti‑PD‑1 combined with neoadjuvant chemotherapy in esophageal squamous cell carcinoma
Xinke Zhang, A. Gari, Mei Li, Jierong Chen, Chunhua Qu, Lihong Zhang, Jiewei Chen
Angiogenic and molecular diversity determine hepatic melanoma metastasis and response to anti-angiogenic treatment
Sebastian A. Wohlfeil, Verena Häfele, Bianca Dietsch, Céline Weller, Carsten Sticht, Anna Sophia Jauch, Manuel Winkler, Christian David Schmid, Anna Lena Irkens, Ana Olsavszky, Kai Schledzewski, Philipp-Sebastian Reiners-Koch, Sergij Goerdt, Cyrill Géraud
Tumor angiogenesis at baseline identified by 18F-Alfatide II PET/CT may predict survival among patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy
Yuchun Wei, Xueting Qin, Xiaoli Liu, Jinsong Zheng, Xiaohui Luan, Yue Zhou, Jinming Yu, Shuanghu Yuan
High frequency of PDGFRA and MUC family gene mutations in diffuse hemispheric glioma, H3 G34-mutant: a glimmer of hope?
Wanming Hu, Hao Duan, Sheng Zhong, Jing Zeng, Yonggao Mou
Mutational signatures reveal ternary relationships between homologous recombination repair, APOBEC, and mismatch repair in gynecological cancers
Amir Farmanbar, Sanaz Firouzi, Robert Kneller, Hossein Khiabanian
Radiomic analysis for predicting prognosis of colorectal cancer from preoperative 18F-FDG PET/CT
Lilang Lv, Bowen Xin, Yichao Hao, Ziyi Yang, Junyan Xu, Lisheng Wang, Xiuying Wang, Shaoli Song, Xiaomao Guo
Targets preliminary screening for the fresh natural drug molecule based on Cosine-correlation and similarity-comparison of local network
Pengcheng Zhao, Lin Lin, Mozheng Wu, Lili Wang, Qi Geng, Li Li, Ning Zhao, Jianyu Shi, Cheng Lu
IRF-2 inhibits cancer proliferation by promoting AMER-1 transcription in human gastric cancer
Yan-Jie Chen, Shu-Neng Luo, Hao Wu, Ning-Ping Zhang, Ling Dong, Tao-Tao Liu, Li Liang, Xi-Zhong Shen
Alterations in the gut microbiome and metabolome profiles of septic rats treated with aminophylline
Yuanzhe Li, Huayan Zhao, Guiying Sun, Yongtao Duan, Yanjun Guo, Lina Xie, Xianfei Ding
From GWAS to drug screening: repurposing antipsychotics for glioblastoma
Wei-Zhi Lin, Yen-Chun Liu, Meng-Chang Lee, Chi-Tun Tang, Gwo-Jang Wu, Yu-Tien Chang, Chi-Ming Chu, Chia-Yang Shiau
Prediction of occult tumor progression via platelet RNAs in a mouse melanoma model: a potential new platform for early detection of cancer
Yue Yin, Ruilan Jiang, Mingwang Shen, Zhaofang Li, Ni Yan, Junqiao Feng, Hong Jiang, Jiaxin Lv, Lijuan Shi, Lina Wang, Xi Liu, Kaiyun Zhang, Di Chen
Sex-specific differences in plasma lipid profiles are associated with Gulf War Illness
Sarah Oberlin, Aurore Nkiliza, Megan Parks, James E. Evans, Nancy Klimas, Andrew P. Keegan, Kimberly Sullivan, Maxine H. Krengel, Michael Mullan, Fiona Crawford, Laila Abdullah
Clinical utility of cerebrospinal fluid-derived circular RNAs in lung adenocarcinoma patients with brain metastases
Zhen Wang, Ruoying Yu, Xiaoxi Chen, Hua Bao, Ran Cao, An-Na Li, Qiuxiang Ou, Hai-Yan Tu, Qing Zhou, Xue Wu, Zhi-Bo Lin, Yi-Long Wu
TGF-β1 induced deficiency of linc00261 promotes epithelial–mesenchymal-transition and stemness of hepatocellular carcinoma via modulating SMAD3
Zhanjun Chen, Leyang Xiang, Longhai Li, Huohui Ou, Yinghao Fang, Yuyan Xu, Qin Liu, Zhigang Hu, Yu Huang, Xianghong Li, Dinghua Yang
Characteristics of the sputum microbiome in COPD exacerbations and correlations between clinical indices
Linfan Su, Yixian Qiao, Jinmei Luo, Rong Huang, Zhiwei Li, Hongbing Zhang, Hongmei Zhao, Jing Wang, Yi Xiao
Macitentan attenuates cardiovascular remodelling in infant rats with chronic lung disease
Philipp Baumann, Francesco Greco, Susanne Wiegert, Sven Wellmann, Giovanni Pellegrini, Vincenzo Cannizzaro
CENPF/CDK1 signaling pathway enhances the progression of adrenocortical carcinoma by regulating the G2/M-phase cell cycle
Yu-gang Huang, Dan Li, Li Wang, Xiao-min Su, Xian-bin Tang
BRAF-activated WT1 contributes to cancer growth and regulates autophagy and apoptosis in papillary thyroid carcinoma
Xing Chen, Shan Lin, Ying Lin, Songsong Wu, Minling Zhuo, Ailong Zhang, Junjie Zheng, Zhenhui You
LncRNA NEAT1 facilitates glioma progression via stabilizing PGK1
Jingshan Liang, Changtao Liu, Dezhi Xu, Kang Xie, Aimin Li
Elevated mid-trimester 4-h postprandial triglycerides for predicting late-onset preeclampsia: a prospective screening study
Qing Liu, Zhihong Zhu, Wen Cai, Liu Yang, ShuangDi Li, Jiarong Zhang
B-cell maturation antigen targeting strategies in multiple myeloma treatment, advantages and disadvantages
Shirin Teymouri Nobari, Jafar Nouri Nojadeh, Mehdi Talebi
Global research trends on the links between the gut microbiome and cancer: a visualization analysis
Sa’ed H. Zyoud, Samah W. Al-Jabi, Riad Amer, Muna Shakhshir, Moyad Shahwan, Ammar A. Jairoun, Maha Akkawi, Adham Abu Taha
Pan-cancer quantitation of epithelial-mesenchymal transition dynamics using parallel reaction monitoring-based targeted proteomics approach
Ankit P. Jain, Janani Sambath, Gajanan Sathe, Irene A. George, Akhilesh Pandey, Erik W. Thompson, Prashant Kumar
Methotrexate-loaded nanoparticles ameliorate experimental model of autoimmune arthritis by regulating the balance of interleukin-17-producing T cells and regulatory T cells
Jin-Sil Park, Donghyun Lee, SeungCheon Yang, Ha Yeon Jeong, Hyun Sik Na, Keun-Hyung Cho, JeongWon Choi, Heebeom Koo, Mi-La Cho, Sung-Hwan Park
Ligand-activated PPARδ expression promotes hepatocellular carcinoma progression by regulating the PI3K-AKT signaling pathway
Wei Han, Nan Wang, Rui Kong, Wen Bao, Jie Lu
Interaction between a diabetes-related methylation site (TXNIP cg19693031) and variant (GLUT1 rs841853) on fasting blood glucose levels among non-diabetics
Hao-Hung Tsai, Chao-Yu Shen, Chien-Chang Ho, Shu-Yi Hsu, Disline Manli Tantoh, Oswald Ndi Nfor, Shin-Lin Chiu, Ying-Hsiang Chou, Yung-Po Liaw
The POR rs10954732 polymorphism decreases susceptibility to hepatocellular carcinoma and hepsin as a prognostic biomarker correlated with immune infiltration based on proteomics
Yan Fang, Hongming Yang, Guiming Hu, Jiakun Lu, Jun Zhou, Na Gao, Yuhan Gu, Cunzhen Zhang, Jinhuan Qiu, Yuanyuan Guo, Yunfei Zhang, Qiang Wen, Hailing Qiao
Adiponectin suppresses tumor growth of nasopharyngeal carcinoma through activating AMPK signaling pathway
Zongmeng Zhang, Jinlin Du, Hui Shi, Shuai Wang, Yunjing Yan, Qihua Xu, Sujin Zhou, Zhenggang Zhao, Yunping Mu, Chaonan Qian, Allan Zijian Zhao, Sumei Cao, Fanghong Li
A web-based prediction model for overall survival of elderly patients with early renal cell carcinoma: a population-based study
Jinkui Wang, Jie Tang, Tiaoyao Chen, Song Yue, Wanting Fu, Zulong Xie, Xiaozhu Liu
Identification of UAP1L1 as a critical factor for prostate cancer and underlying molecular mechanism in tumorigenicity
Xing-cheng Wu, Yu-zhong Yu, Yu-zhi Zuo, Xian-Lu Song, Zhi-en Zhou, Yu Xiao, Dao-sheng Luo, Wei-gang Yan, Shan-Chao Zhao
In vivo detection of dysregulated choline metabolism in paclitaxel-resistant ovarian cancers with proton magnetic resonance spectroscopy
Jing Lu, Ying Li, Yong Ai Li, Li Wang, An Rong Zeng, Xiao Liang Ma, Jin Wei Qiang
Characterization of DNA methylation as well as mico-RNA expression and screening of epigenetic markers in adipogenesis
Yong Zhang, Fancheng Chen, Fangxue Zhang, Xiaowei Huang
Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of myalgic encephalomyelitis/chronic fatigue syndrome patients
Natalie Eaton-Fitch, Stanley Du Preez, Hélène Cabanas, Katsuhiko Muraki, Donald Staines, Sonya Marshall-Gradisnik
Physiological assessment of orthostatic intolerance in chronic fatigue syndrome
Benjamin H. Natelson, Jin-Mann S. Lin, Michelle Blate, Sarah Khan, Yang Chen, Elizabeth R. Unger
CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587
Kun Lin, Shang-Hang Shen, Feng Lu, Pengfeng Zheng, Shizhong Wu, Jingwei Liao, Xiaohang Jiang, Guangming Zeng, De Wei
Immune cell profiles of patients with interstitial cystitis/bladder pain syndrome
Robert M. Moldwin, Vishaan Nursey, Oksana Yaskiv, Siddhartha Dalvi, Eric J. Macdonald, Michael Funaro, Chengliang Zhang, William DeGouveia, Marina Ruzimovsky, Horacio R. Rilo, Edmund J. Miller, Souhel Najjar, Inna Tabansky, Joel N. H. Stern
The relationship between frailty, nutritional status, co-morbidity, CT-body composition and systemic inflammation in patients with COVID-19
Josh McGovern, Yassir Al-Azzawi, Olivia Kemp, Peter Moffitt, Conor Richards, Ross D. Dolan, Barry J. Laird, Donald C. McMillan, Donogh Maguire
How mycobacterium tuberculosis infection could lead to the increasing risks of chronic fatigue syndrome and the potential immunological effects: a population-based retrospective cohort study
Tse-Yen Yang, Cheng-Li Lin, Wei-Cheng Yao, Chon-Fu Lio, Wen-Po Chiang, Kuan Lin, Chien-Feng Kuo, Shin-Yi Tsai
An artificial intelligence method to assess the tumor microenvironment with treatment outcomes for gastric cancer patients after gastrectomy
Tao Chen, Xunjun Li, Qingyi Mao, Yiyun Wang, Hanyi Li, Chen Wang, Yuyang Shen, Erjia Guo, Qinglie He, Jie Tian, Mansheng Zhu, Jing Wu, Weiqi Liang, Hao Liu, Jiang Yu, Guoxin Li
Promotion of microRNA-146a by histone deacetylase 4 silencing contributes to radiosensitization of esophageal carcinoma
Zhonghua Lu, Yifei Yun, Yutong Zhang, Yao Ou, Meihua Wang
Derivation and validation of urinary TIMP-1 for the prediction of acute kidney injury and mortality in critically ill children
Hui Huang, Qiang Lin, Xiaomei Dai, Jiao Chen, Zhenjiang Bai, Xiaozhong Li, Fang Fang, Yanhong Li
Proton magnetic resonance spectroscopy detects cerebral metabolic derangement in a mouse model of brain coenzyme a deficiency
Yanan Li, Jeffrey Steinberg, Zane Coleman, Shubo Wang, Chitra Subramanian, Yimei Li, Zoltan Patay, Walter Akers, Charles O. Rock, Suzanne Jackowski, Puneet Bagga
FK506 and Lactobacillus acidophilus ameliorate acute graft-versus-host disease by modulating the T helper 17/regulatory T-cell balance
Jin-Ah Beak, Min-Jung Park, Se-Young Kim, JooYeon Jhun, Jin Seok Woo, Jeong Won Choi, Hyun Sik Na, Soon Kyu Lee, Jong Young Choi, Mi-La Cho
Mini-XT, a miniaturized tagmentation-based protocol for efficient sequencing of SARS-CoV-2
Marc Fuchs, Clara Radulescu, Miao Tang, Arun Mahesh, Deborah Lavin, Syed Umbreen, James McKenna, Mark Smyth, Eilís McColgan, Zoltan Molnar, Chris Baxter, Timofey Skvortsov, Aditi Singh, Fiona Rogan, Julia Miskelly, Stephen Bridgett, Derek Fairley, David A. Simpson
Activation of miR-500a-3p/CDK6 axis suppresses aerobic glycolysis and colorectal cancer progression
Yu Liu, Wentao Tang, Li Ren, Tianyu Liu, Meng Yang, Ye Wei, Yijiao Chen, Meiling Ji, Guosong Chen, Wenju Chang, Jianmin Xu
LPL, FNDC5 and PPARγ gene polymorphisms related to body composition parameters and lipid metabolic profile in adolescents from Southern Italy
Benedetta Perrone, Paola Ruffo, Samanta Zelasco, Cinzia Giordano, Catia Morelli, Ines Barone, Stefania Catalano, Sebastiano Andò, Diego Sisci, Giovanni Tripepi, Corrado Mammì, Daniela Bonofiglio, Francesca Luisa Conforti
The association between bilirubin and hypertension among a Chinese ageing cohort: a prospective follow-up study
Chen Tang, Hanxiang Jiang, Bin Zhao, Yi Lin, Shengnan Lin, Tianmu Chen, Yanhua Su, Yiqin Zhang, Lina Zhou, Lianmeng Li, Jincheng Lin, Zhonghua Lu, Yao Wang, Zeyu Zhao, Longjian Liu, Yuxin Wang, Jie Zhang, Heqing Shen
Pan-cancer analyses of pyroptosis with functional implications for prognosis and immunotherapy in cancer
Aibin Liu, Lin Shen, Na Li, Liangfang Shen, Zhanzhan Li
Microbiota medicine: towards clinical revolution
Prisca Gebrayel, Carole Nicco, Souhaila Al Khodor, Jaroslaw Bilinski, Elisabetta Caselli, Elena M. Comelli, Markus Egert, Cristina Giaroni, Tomasz M. Karpinski, Igor Loniewski, Agata Mulak, Julie Reygner, Paulina Samczuk, Matteo Serino, Mariusz Sikora, Annalisa Terranegra, Marcin Ufnal, Romain Villeger, Chantal Pichon, Peter Konturek, Marvin Edeas
Non-linear relationship between the body roundness index and incident type 2 diabetes in Japan: a secondary retrospective analysis
Liling Wu, Hailu Pu, Man Zhang, Haofei Hu, Qijun Wan
Poor oral health may prolong COVID-19 illness
Shipra Gupta, Timo Sorsa, Ella Brandt, Ismo T. Räisänen, Ritin Mohindra, Kapil Goyal
Tumor-B-cell interactions promote isotype switching to an immunosuppressive IgG4 antibody response through upregulation of IL-10 in triple negative breast cancers
Nicole J. Toney, Lynn M. Opdenaker, Kader Cicek, Lisa Frerichs, Christopher Ryan Kennington, Samuel Oberly, Holly Archinal, Rajasekharan Somasundaram, Jennifer Sims-Mourtada
Clinical validation of a 90-gene expression test for tumor tissue of origin diagnosis: a large-scale multicenter study of 1417 patients
Wei Sun, Wei Wu, Qifeng Wang, Qian Yao, Qin Feng, Yue Wang, Yu Sun, Yunying Liu, Qian Lai, Gu Zhang, Peng Qi, Yifeng Sun, Chenhui Qian, Wanli Ren, Zhengzhi Luo, Jinying Chen, Hongying Wang, Qinghua Xu, Xiaoyan Zhou, Wenyong Sun, Dongmei Lin
hsa-miR-875-5p inhibits tumorigenesis and suppresses TGF-β signalling by targeting USF2 in gastric cancer
Shenshuo Gao, Zhikai Zhang, Xubin Wang, Yan Ma, Chensheng Li, Hongjun Liu, Changqing Jing, Leping Li, Xiaobo Guo
Lenvatinib inhibits the growth of gastric cancer patient-derived xenografts generated from a heterogeneous population
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Exosomes in the tumor microenvironment of cholangiocarcinoma: current status and future perspectives
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Tumors carrying BRAF-mutations over-express NAMPT that is genetically amplified and possesses oncogenic properties
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RUNX3-mediated circDYRK1A inhibits glutamine metabolism in gastric cancer by up-regulating microRNA-889-3p-dependent FBXO4
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Superior physical and mental health of healthy volunteers before and five years after mobilized stem cell donation
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Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis
Qi Chen, Xi Liang, Tianzhou Wu, Jing Jiang, Yongpo Jiang, Sheng Zhang, Yanyun Ruan, Huaping Zhang, Chao Zhang, Peng Chen, Yuhang Lv, Jiaojiao Xin, Dongyan Shi, Xin Chen, Jun Li, Yinghe Xu
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Untargeted metabolomics analysis of esophageal squamous cell cancer progression
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The monomer TEC of blueberry improves NASH by augmenting tRF-47-mediated autophagy/pyroptosis signaling pathway
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Milan Haffke, Helma Freitag, Gordon Rudolf, Martina Seifert, Wolfram Doehner, Nadja Scherbakov, Leif Hanitsch, Kirsten Wittke, Sandra Bauer, Frank Konietschke, Friedemann Paul, Judith Bellmann-Strobl, Claudia Kedor, Carmen Scheibenbogen, Franziska Sotzny
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SIRPα and PD1 expression on tumor-associated macrophage predict prognosis of intrahepatic cholangiocarcinoma
Hui Yang, Meimei Yan, Wei Li, Linping Xu
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Zheyi Dong, Qian Wang, Yujing Ke, Weiguang Zhang, Quan Hong, Chao Liu, Xiaomin Liu, Jian Yang, Yue Xi, Jinlong Shi, Li Zhang, Ying Zheng, Qiang Lv, Yong Wang, Jie Wu, Xuefeng Sun, Guangyan Cai, Shen Qiao, Chengliang Yin, Shibin Su, Xiangmei Chen
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Identification of blood-based key biomarker and immune infiltration in Immunoglobulin A nephropathy by comprehensive bioinformatics analysis and a cohort validation
Jie Xu, Xiahong Shen, Xing Wei, Jie Ding, Jiaojiao Yuan, Zhen Weng, Yang He
Mass spectrometric study of variation in kinin peptide profiles in nasal fluids and plasma of adult healthy individuals
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Xue Li, Lihong Lu, Wenting Hou, Fei Wang, Ting Huang, Zhipeng Meng, Minmin Zhu
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Fu-Shun Yen, Shiow-Ing Wang, Shih-Yi Lin, Yung-Hsiang Chao, James Cheng-Chung Wei
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Kaiyan Chen, Fanrong Zhang, Xiaoqing Yu, Zhiyu Huang, Lei Gong, Yanjun Xu, Hui Li, Sizhe Yu, Yun Fan
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Liyan Wang, Bin Li, Xiaoyuan Yi, Xuhua Xiao, Qinghua Zheng, Lei Ma
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Dong Ye, Mengdan Gong, Yongqin Deng, Shuai Fang, Yujie Cao, Yizhen Xiang, Zhisen Shen
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A randomized controlled trial of the influence of yoga for women with symptoms of post-traumatic stress disorder
Lei Yi, Yunling Lian, Ning Ma, Ni Duan
β-cell mitochondria in diabetes mellitus: a missing puzzle piece in the generation of hPSC-derived pancreatic β-cells?
Abdoulaye Diane, Noora Ali Al-Shukri, Razik Bin Abdul Mu-u-min, Heba H. Al-Siddiqi
Evaluating machine learning-powered classification algorithms which utilize variants in the GCKR gene to predict metabolic syndrome: Tehran Cardio-metabolic Genetics Study
Mahdi Akbarzadeh, Nadia Alipour, Hamed Moheimani, Asieh Sadat Zahedi, Firoozeh Hosseini-Esfahani, Hossein Lanjanian, Fereidoun Azizi, Maryam S. Daneshpour
Risk of confounding variables in multivariate analysis
Bruno Gagnon, Andrew M. R. Hanna
Prediction of acute kidney injury after cardiac surgery: model development using a Chinese electronic health record dataset
Hang Zhang, Zhongtian Wang, Yingdan Tang, Xin Chen, Dongfang You, Yaqian Wu, Min Yu, Wen Chen, Yang Zhao, Xin Chen
The role of neutrophil elastase in aortic valve calcification
Yan Liu, Peng Jiang, Liqin An, Mengying Zhu, Jin Li, Yue Wang, Qin Huang, Yi Xiang, Xiaorong Li, Qiong Shi, Yaguang Weng
Fetal growth restriction: associated genetic etiology and pregnancy outcomes in a tertiary referral center
Meiying Cai, Na Lin, Linjuan Su, Xiaoqing Wu, Xiaorui Xie, Shiyi Xu, Xianguo Fu, Liangpu Xu, Hailong Huang
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Tong Li, Huiyuan Cao, Sa Wu, Peimin Zhong, Jie Ding, Jing Wang, Fangfang Wang, Zhiwei He, Guo-Liang Huang
Evaluation of the effects of meteorological factors on COVID-19 prevalence by the distributed lag nonlinear model
Hongjing Ai, Rongfang Nie, Xiaosheng Wang
Cisplatin resistance-related multi-omics differences and the establishment of machine learning models
Qihai Sui, Zhencong Chen, Zhengyang Hu, Yiwei Huang, Jiaqi Liang, Guoshu Bi, Yunyi Bian, Mengnan Zhao, Cheng Zhan, Zongwu Lin, Qun Wang, Lijie Tan
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Dongshen Ma, Qin Zhang, Qianqian Duan, Yuan Tan, Tingting Sun, Chuang Qi, Yong Qin, Hui Liu
Irritable bowel syndrome and microbiome; Switching from conventional diagnosis and therapies to personalized interventions
Pouyan Ghaffari, Saeed Shoaie, Lars K. Nielsen
A novel rat model for cerebral venous sinus thrombosis: verification of similarity to human disease via clinical analysis and experimental validation
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The global prevalence of oropharyngeal dysphagia in different populations: a systematic review and meta-analysis
Fatemeh Rajati, Nassim Ahmadi, Zahra Al-sadat Naghibzadeh, Mohsen Kazeminia
Early and strong antibody responses to SARS-CoV-2 predict disease severity in COVID-19 patients
Jānis Plūme, Artis Galvanovskis, Sindija Šmite, Nadezhda Romanchikova, Pawel Zayakin, Aija Linē
XGBoost-based and tumor-immune characterized gene signature for the prediction of metastatic status in breast cancer
Qingqing Li, Hui Yang, Peipei Wang, Xiaocen Liu, Kun Lv, Mingquan Ye
The “Great Debate” at Immunotherapy Bridge 2021, December 1st–2nd, 2021
Paolo A. Ascierto, Lisa H. Butterfield, Olivera J. Finn, Andrew Futreal, Omid Hamid, Theresa LaVallee, Michael A. Postow, Igor Puzanov, Jeffrey Sosman, Bernard A. Fox, Patrick Hwu
circMAP3K4 regulates insulin resistance in trophoblast cells during gestational diabetes mellitus by modulating the miR-6795-5p/PTPN1 axis
Runyu Du, Na Wu, Yu Bai, Lei Tang, Ling Li
Identifying causal genes for stroke via integrating the proteome and transcriptome from brain and blood
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Transcriptomic profiling of pemphigus lesion infiltrating mononuclear cells reveals a distinct local immune microenvironment and novel lncRNA regulators
Zi-xuan Huang, Peng Qu, Kan-kan Wang, Jie Zheng, Meng Pan, Hai-qin Zhu
FOXO transcriptional activity is associated with response to chemoradiation in EAC
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The need for uniform and coordinated practices involving centrally manufactured cell therapies
David Stroncek, Anh Dinh, Herleen Rai, Nan Zhang, Rob Somerville, Sandhya Panch
Angiopoietin2-mediated caveolin1 phosphorylation regulating transcytosis of renal tubular epithelial cell contributes to the occurrence of albuminuria under high glucose exposure
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Identification of molecular subtypes and a novel prognostic model of diffuse large B-cell lymphoma based on a metabolism-associated gene signature
Jing He, Ziwei Chen, Qingfeng Xue, Pingping Sun, Yuan Wang, Cindy Zhu, Wenyu Shi
The genomic landscape of invasive stratified mucin-producing carcinoma of the uterine cervix: the first description based on whole-exome sequencing
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Mechanism and clinical value of exosomes and exosomal contents in regulating solid tumor radiosensitivity
Huihui Sun, Rui Sun, Xing Song, Wendong Gu, Yingjie Shao
Identification of invasion-metastasis associated MiRNAs in gallbladder cancer by bioinformatics and experimental validation
Jiasheng Cao, Huijiang Shao, Jiahao Hu, Renan Jin, Anyun Feng, Bin Zhang, Shijie Li, Tianen Chen, Sarun Jeungpanich, Win Topatana, Yitong Tian, Ziyi Lu, Xiujun Cai, Mingyu Chen
Building a model for predicting metabolic syndrome using artificial intelligence based on an investigation of whole-genome sequencing
Nai-Wei Hsu, Kai-Chen Chou, Yu-Ting Tina Wang, Chung-Lieh Hung, Chien-Feng Kuo, Shin-Yi Tsai
TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5
Xiaoying Jin, Dandan Wang, Mengxia Lei, Yan Guo, Yuqing Cui, Fengzhi Chen, Weiling Sun, Xuesong Chen
New challenges for microRNAs in acute pancreatitis: progress and treatment
Wence Zhou, Shi Dong, Zhou Chen, Xin Li, Wenkai Jiang
ICH-LR2S2: a new risk score for predicting stroke-associated pneumonia from spontaneous intracerebral hemorrhage
Jing Yan, Weiqi Zhai, Zhaoxia Li, LingLing Ding, Jia You, Jiayi Zeng, Xin Yang, Chunjuan Wang, Xia Meng, Yong Jiang, Xiaodi Huang, Shouyan Wang, Yilong Wang, Zixiao Li, Shanfeng Zhu, Yongjun Wang, Xingquan Zhao, Jianfeng Feng
CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signaling
Lili Zhu, Xiaobei Yang, Jingyu Feng, Jian Mao, Qidong Zhang, Mengru He, Yang Mi, Yingwu Mei, Ge Jin, Haifeng Zhang
Enhanced DNA and RNA pathogen detection via metagenomic sequencing in patients with pneumonia
Yukun He, Kechi Fang, Xing Shi, Donghong Yang, Lili Zhao, Wenyi Yu, Yali Zheng, Yu Xu, Xinqian Ma, Li Chen, Yu Xie, Yan Yu, Jing Wang, Zhancheng Gao
Comparison of immune cells and diagnostic markers between spondyloarthritis and rheumatoid arthritis by bioinformatics analysis
Jiaqian Wang, Yuan Xue, Liang Zhou
Single-cell N6-methyladenosine regulator patterns guide intercellular communication of tumor microenvironment that contribute to colorectal cancer progression and immunotherapy
Yuzhen Gao, Hao Wang, Shipeng Chen, Rui An, Yadong Chu, Guoli Li, Yanzhong Wang, Xinyou Xie, Jun Zhang
SRSF9 promotes colorectal cancer progression via stabilizing DSN1 mRNA in an m6A-related manner
Xiaoyu Wang, Xiansheng Lu, Ping Wang, Qiaoyu Chen, Le Xiong, Minshan Tang, Chang Hong, Xiaowen Lin, Kaixi Shi, Li Liang, Jie Lin
An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
Charles P. Hinzman, Meth Jayatilake, Sunil Bansal, Brian L. Fish, Yaoxiang Li, Yubo Zhang, Shivani Bansal, Michael Girgis, Anton Iliuk, Xiao Xu, Jose A. Fernandez, John H. Griffin, Elizabeth A. Ballew, Keith Unger, Marjan Boerma, Meetha Medhora, Amrita K. Cheema
The “Great Debate” at Melanoma Bridge 2021, December 2nd–4th, 2021
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Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification
Fang Lyu, Yunxue Li, Zhecheng Yan, Qingliu He, Lulin Cheng, Pu Zhang, Bing Liu, Chunyu Liu, Yarong Song, Yifei Xing
Hsa_circ_0000497 and hsa_circ_0000918 contributed to peritoneal metastasis of ovarian cancer via ascites
Ning Luo, Zubaidan Sulaiman, Chunyan Wang, Jinye Ding, Yingying Chen, Biting Liu, Zhongping Cheng, Shupeng Liu
The PDE4 inhibitor tanimilast shows distinct immunomodulatory properties associated with a type 2 endotype and CD141 upregulation
Hoang Oanh Nguyen, Valentina Salvi, Laura Tiberio, Fabrizio Facchinetti, Mirco Govoni, Gino Villetti, Maurizio Civelli, Ilaria Barbazza, Carolina Gaudenzi, Mauro Passari, Tiziana Schioppa, Francesca Sozio, Annalisa Del Prete, Silvano Sozzani, Daniela Bosisio
Effects of preoperative high-oral protein loading on short- and long-term renal outcomes following cardiac surgery: a cohort study
Faeq Husain-Syed, David R. Emlet, Jochen Wilhelm, Tommaso Hinna Danesi, Fiorenza Ferrari, Pércia Bezerra, Salvador Lopez-Giacoman, Gianluca Villa, Khodr Tello, Horst-Walter Birk, Werner Seeger, Davide Giavarina, Loris Salvador, Dana Y. Fuhrman, John A. Kellum, Claudio Ronco, Carlotta Caprara, Valentina Corradi, Massimo Cal, Carla Estremadoyro, Renhua Lu, Sara Samoni, Aashish Sharma, Lorenzo Tofani, Grazia Maria Virzì
Inhibition of NOS1 promotes the interferon response of melanoma cells
Xi Chen, Zhiwei Zou, Qianli Wang, Wenwen Gao, Sisi Zeng, Shuangyan Ye, Pengfei Xu, Mengqiu Huang, Keyi Li, Jianping Chen, Zhuo Zhong, Qianbing Zhang, Bingtao Hao, Qiuzhen Liu
Patient-derived xenograft (PDX) models, applications and challenges in cancer research
Shahrokh Abdolahi, Zeinab Ghazvinian, Samad Muhammadnejad, Mahshid Saleh, Hamid Asadzadeh Aghdaei, Kaveh Baghaei
IL-32 promotes the occurrence of atopic dermatitis by activating the JAK1/microRNA-155 axis
Jing Chang, Bin Zhou, Zhu Wei, Yongqi Luo
Extracellular vesicles from the inflammatory microenvironment regulate the osteogenic and odontogenic differentiation of periodontal ligament stem cells by miR-758-5p/LMBR1/BMP2/4 axis
Chaoting Yan, Na Li, Tong Xiao, Xiaying Ye, Lin Fu, Yu Ye, Tao Xu, Jinhua Yu
Identification of mutation patterns and circulating tumour DNA-derived prognostic markers in advanced breast cancer patients
Hao Liao, Jiayang Zhang, Tiantian Zheng, Xiaoran Liu, Jianxin Zhong, Bin Shao, Xiaoxi Dong, Xiaohong Wang, Pan Du, Bonnie L. King, Shidong Jia, Jianjun Yu, Huiping Li
5-fluorouracil treatment of patient-derived scaffolds from colorectal cancer reveal clinically critical information
Simona Salerno, Anders Ståhlberg, André Holdfeldt, Elinor Bexe Lindskog, Göran Landberg
Single-cell landscape of immunocytes in patients with extrahepatic cholangiocarcinoma
Lei Xu, Yun Lu, Zhengdong Deng, Xiangyu Li, Yuanxin Shi, Kai Zhao, Wei Yao, Jianming Wang
VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway
Zhangya Pu, Dan G. Duda, Yuanyuan Zhu, Siya Pei, Xiaofang Wang, Yan Huang, Panpan Yi, Zebing Huang, Fang Peng, Xingwang Hu, Xuegong Fan
Recommendations for addressing the translational gap between experimental and clinical research on amyloid diseases
Miriam Solomon, Vito Foderà, Annette Eva Langkilde, Perry Elliott, Fabrizio Tagliavini, Trevor Forsyth, Oxana Klementieva, Vittorio Bellotti
5-methylcytosine RNA methyltransferases and their potential roles in cancer
Mingyang Li, Zijia Tao, Yiqiao Zhao, Lei Li, Jianyi Zheng, Zeyu Li, Xiaonan Chen
Causal relationship between physical activity, leisure sedentary behaviors and COVID-19 risk: a Mendelian randomization study
Xiong Chen, Xiaosi Hong, Wenjing Gao, Shulu Luo, Jiahao Cai, Guochang Liu, Yinong Huang
CDK4/6 inhibitors sensitize gammaherpesvirus-infected tumor cells to T-cell killing by enhancing expression of immune surface molecules
Yiquan Wu, Prabha Shrestha, Natalie M. Heape, Robert Yarchoan
Machine learning for the prediction of acute kidney injury in patients with sepsis
Suru Yue, Shasha Li, Xueying Huang, Jie Liu, Xuefei Hou, Yumei Zhao, Dongdong Niu, Yufeng Wang, Wenkai Tan, Jiayuan Wu
St13 protects against disordered acinar cell arachidonic acid pathway in chronic pancreatitis
Rong-chang Cao, Wan-jun Yang, Wang Xiao, Lei Zhou, Jie-hui Tan, Meng Wang, Zhi-tao Zhou, Huo-ji Chen, Jia Xu, Xue-mei Chen, Yang-chen Jin, Jia-yu Lin, Jun-ling Zeng, Shu-ji Li, Min Luo, Guo-dong Hu, Jin Jin, Xiao-bing Yang, Da Huo, Jie Zhou, Guo-wei Zhang
The interaction between long non-coding RNA LINC01564 and POU2F1 promotes the proliferation and metastasis of gastric cancer
Jixu Wang, Futao Hou, Lusheng Tang, Ke Xiao, Tengfei Yang, Zhiqiang Wang, Gu Liu
Sclerostin is a promising therapeutic target for oral inflammation and regenerative dentistry
Chufang Liao, Shanshan Liang, Yining Wang, Ting Zhong, Xiangning Liu
SIRT1 prevents cigarette smoking-induced lung fibroblasts activation by regulating mitochondrial oxidative stress and lipid metabolism
Yue Zhang, Ting Li, Miaoxia Pan, Wei Wang, Wenhui Huang, Yafei Yuan, Zhanzhan Xie, Yixin Chen, Jun Peng, Xu Li, Ying Meng
Association between early ondansetron administration and in-hospital mortality in critically ill patients: analysis of the MIMIC-IV database
Yingying Fang, Chao Xiong, Xinghe Wang
Circulating miRNAs in extracellular vesicles related to treatment response in patients with idiopathic membranous nephropathy
In O. Sun, Yun-Ui Bae, Haekyung Lee, Hyoungnae Kim, Jin Seok Jeon, Hyunjin Noh, Jong-Soo Choi, Kyung-Oh Doh, Soon Hyo Kwon
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
Åslaug Helland, Hege G. Russnes, Gro Live Fagereng, Khalid Al-Shibli, Yvonne Andersson, Thomas Berg, Line Bjørge, Egil Blix, Bodil Bjerkehagen, Sigmund Brabrand, Marte Grønlie Cameron, Astrid Dalhaug, Dalia Dietzel, Tom Dønnem, Espen Enerly, Åsmund Flobak, Sverre Fluge, Bjørnar Gilje, Bjørn Tore Gjertsen, Bjørn Henning Grønberg, Kari Grønås, Tormod Guren, Hanne Hamre, Åse Haug, Daniel Heinrich, Geir Olav Hjortland, Eivind Hovig, Randi Hovland, Ann-Charlotte Iversen, Emiel Janssen, Jon Amund Kyte, Hedda von der Lippe Gythfeldt, Ragnhild Lothe, Jo-Åsmund Lund, Leonardo Meza-Zepeda, Monica Cheng Munthe-Kaas, Olav Toai Duc Nguyen, Pitt Niehusmann, Hilde Nilsen, Katarina Puco, Anne Hansen Ree, Tonje Bøyum Riste, Karin Semb, Eli Sihn Samdal Steinskog, Andreas Stensvold, Pål Suhrke, Øyvind Tennøe, Geir E. Tjønnfjord, Liv Jorunn Vassbotn, Eline Aas, Kristine Aasebø, Kjetil Tasken, Sigbjørn Smeland
Exploring the association between birthweight and breast cancer using summary statistics from a perspective of genetic correlation, mediation, and causality
Meng Zhang, Jiahao Qiao, Shuo Zhang, Ping Zeng
The progression rate of spinocerebellar ataxia type 3 varies with disease stage
Linliu Peng, Yun Peng, Zhao Chen, Chunrong Wang, Zhe Long, Huirong Peng, Yuting Shi, Lu Shen, Kun Xia, Vanessa B. Leotti, Laura Bannach Jardim, Beisha Tang, Rong Qiu, Hong Jiang
RNA adenosine modifications related to prognosis and immune infiltration in osteosarcoma
Shijie Chen, Jin Zeng, Liping Huang, Yi Peng, Zuyun Yan, Aiqian Zhang, Xingping Zhao, Jun Li, Ziting Zhou, Sidan Wang, Shengyu Jing, Minghua Hu, Yuezhan Li, Dong Wang, Weiguo Wang, Haiyang Yu, Jinglei Miao, Jinsong Li, Youwen Deng, Yusheng Li, Tang Liu, Dabao Xu
Heat shock protein A4 ablation leads to skeletal muscle myopathy associated with dysregulated autophagy and induced apoptosis
Manar Elkenani, Amal Z. Barakat, Torsten Held, Daniel Marques Rodrigues, Sherok Mobarak, Surabhi Swarnka, Ibrahim M. Adham, Belal A. Mohamed
Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study
Francesco Ravera, Roberto Borea, Gabriella Cirmena, Martina Dameri, Lorenzo Ferrando, Maurizio Gallo, Cecilia Casini, Neri Fallani, Mario Stabile, Valentina Barbero, Roberto Murialdo, Lucia Tixi, Margherita Cappuccio, Andrea Cuboni, Irene Sivieri, Giuseppe Fornarini, Andrea De Maria, Alberto Ballestrero, Gabriele Zoppoli
Clinical validation of full HR-HPV genotyping HPV Selfy assay according to the international guidelines for HPV test requirements for cervical cancer screening on clinician-collected and self-collected samples
Alice Avian, Nicolò Clemente, Elisabetta Mauro, Erica Isidoro, Michela Di Napoli, Sandra Dudine, Anna Del Fabro, Stefano Morini, Tiziana Perin, Fabiola Giudici, Tamara Cammisuli, Nicola Foschi, Marco Mocenigo, Michele Montrone, Chiara Modena, Martina Polenghi, Luca Puzzi, Vjekoslav Tomaic, Giulio Valenti, Riccardo Sola, Shivani Zanolla, Enea Vogrig, Elisabetta Riva, Silvia Angeletti, Massimo Ciccozzi, Santina Castriciano, Maria Pachetti, Matteo Petti, Sandro Centonze, Daniela Gerin, Lawrence Banks, Bruna Marini, Vincenzo Canzonieri, Francesco Sopracordevole, Fabrizio Zanconati, Rudy Ippodrino
“Planeterranean” Diet: extending worldwide the health benefits of Mediterranean Diet based on nutritional properties of locally available foods
Annamaria Colao, Claudia Vetrani, Giovanna Muscogiuri, Luigi Barrea, Antonia Tricopoulou, Laura Soldati, Prisco Piscitelli
SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia
Ming-Ming Liu, Jia Peng, Yuan-Lin Guo, Cheng-Gang Zhu, Na-Qiong Wu, Rui-Xia Xu, Qian Dong, Chuan-Jue Cui, Jian-Jun Li
Bulk and single-cell transcriptome profiling reveal necroptosis-based molecular classification, tumor microenvironment infiltration characterization, and prognosis prediction in colorectal cancer
Wenqin Luo, Wenqiang Xiang, Lu Gan, Ji Che, Jing Li, Yichao Wang, Lingyu Han, Ruiqi Gu, Li Ye, Renjie Wang, Xiuping Zhang, Ye Xu, Weixing Dai, Shaobo Mo, Qingguo Li, Guoxiang Cai
The future of cancer immunotherapy for brain tumors: a collaborative workshop
Christine E. Brown, Samantha Bucktrout, Lisa H. Butterfield, Olga Futer, Evanthia Galanis, Adilia Hormigo, Michael Lim, Hideho Okada, Robert Prins, Sara Siebel Marr, Kirk Tanner
Association between physical activity and infertility: a comprehensive systematic review and meta-analysis
Fangfang Xie, Yanli You, Chong Guan, Yuanjia Gu, Fei Yao, Jiatuo Xu
Serum proteome alterations during conventional and extracorporeal resuscitation in pigs
Patrick Bernhard, Berit Amelie Bretthauer, Sam Joé Brixius, Hannah Bügener, Johannes Elias Groh, Christian Scherer, Domagoj Damjanovic, Jörg Haberstroh, Georg Trummer, Christoph Benk, Friedhelm Beyersdorf, Oliver Schilling, Jan-Steffen Pooth
Exhaustion of CAR T cells: potential causes and solutions
Taku Kouro, Hidetomo Himuro, Tetsuro Sasada
Natural killer cells: a promising immunotherapy for cancer
Junfeng Chu, Fengcai Gao, Meimei Yan, Shuang Zhao, Zheng Yan, Bian Shi, Yanyan Liu
Lymphocytes in tumor-draining lymph nodes co-cultured with autologous tumor cells for adoptive cell therapy
Kazumi Okamura, Satoshi Nagayama, Tomohiro Tate, Hiu Ting Chan, Kazuma Kiyotani, Yusuke Nakamura
Electrolysis of water is an effective source of oxygen at high altitude
Xinjun Tang, Li Liang, Lijuan Hu, Yuanlin Song
Discovery of new therapeutic targets in ovarian cancer through identifying significantly non-mutated genes
Halema Al-Farsi, Iman Al-Azwani, Joel A. Malek, Lotfi Chouchane, Arash Rafii, Najeeb M. Halabi
Synergistic effect of the commonest residual risk factors, remnant cholesterol, lipoprotein(a), and inflammation, on prognosis of statin-treated patients with chronic coronary syndrome
Hui-Hui Liu, Yuan-Lin Guo, Cheng-Gang Zhu, Na-Qiong Wu, Ying Gao, Rui-Xia Xu, Qian Dong, Jie Qian, Ke-Fei Dou, Jian-Jun Li
DLEU1 promotes cell survival by preventing DYNLL1 degradation in esophageal squamous cell carcinoma
Qihang Li, Zhiyu Zhang, HongChao Jiang, Jun Hou, Yuhang Chai, Hongxing Nan, Feng Li, Lianghai Wang
Platinum-induced mitochondrial OXPHOS contributes to cancer stem cell enrichment in ovarian cancer
Shruthi Sriramkumar, Riddhi Sood, Thomas D. Huntington, Ahmed H. Ghobashi, Truc T. Vuong, Tara X. Metcalfe, Weini Wang, Kenneth P. Nephew, Heather M. O’Hagan
mTOR pathway gene mutations predict response to immune checkpoint inhibitors in multiple cancers
Lei Cheng, Yanan Wang, Lixin Qiu, Yuanyuan Chang, Haijiao Lu, Chenchen Liu, Bo Zhang, Yan Zhou, Hao Bai, Liwen Xiong, Hua Zhong, Wei Nie, Baohui Han
Role of chemokine-mediated angiogenesis in resistance towards crizotinib and its reversal by anlotinib in EML4-ALK positive NSCLC
Shasha Wang, Ning Lou, Rongrong Luo, Xuezhi Hao, Yutao Liu, Lin Wang, Yuankai Shi, Xiaohong Han
Transcriptomic datasets of cancer patients treated with immune-checkpoint inhibitors: a systematic review
Szonja Anna Kovács, Balázs Győrffy
Nicotinamide drives T cell activation in the mammary tumor microenvironment
Yang Hu, Norma Bloy, Olivier Elemento, Aitziber Buqué
A gene prognostic index from cellular senescence predicting metastasis and radioresistance for prostate cancer
Dechao Feng, Dengxiong Li, Xu Shi, Qiao Xiong, Facai Zhang, Qiang Wei, Lu Yang
Enhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to males
Mariam Saad, Sandra J. Lee, Aik Choon Tan, Issam M. El Naqa, F. Stephen Hodi, Lisa H. Butterfield, William A. LaFramboise, Walter Storkus, Arivarasan D. Karunamurthy, Jose Conejo-Garcia, Patrick Hwu, Howard Streicher, Vernon K. Sondak, John M. Kirkwood, Ahmad A. Tarhini
Single-cell sequencing analysis reveals gastric cancer microenvironment cells respond vastly different to oxidative stress
Weihua Yu, Guojun Chen, Jiafei Yan, Xianfa Wang, Yiping Zhu, Linghua Zhu
Identifying the critical states and dynamic network biomarkers of cancers based on network entropy
Juntan Liu, Dandan Ding, Jiayuan Zhong, Rui Liu
RAF1 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating LAGE1: an experimental research
Yanshi Li, Min Pan, Tao Lu, Dan Yu, Chuan Liu, Zhihai Wang, Guohua Hu
Integration of radiogenomic features for early prediction of pathological complete response in patients with triple-negative breast cancer and identification of potential therapeutic targets
Ying Zhang, Chao You, Yuchen Pei, Fan Yang, Daqiang Li, Yi-zhou Jiang, Zhimin Shao
Perspectives in Immunotherapy: meeting report from the Immunotherapy Bridge, December 1st–2nd, 2021
Paolo A. Ascierto, Antonio Avallone, Nina Bhardwaj, Carlo Bifulco, Sergio Bracarda, Joshua D. Brody, Luigi Buonaguro, Sandra Demaria, Leisha A. Emens, Robert L. Ferris, Jérôme Galon, Samir N. Khleif, Christopher A. Klebanoff, Tamara Laskowski, Ignacio Melero, Chrystal M. Paulos, Sandro Pignata, Marco Ruella, Inge Marie Svane, Janis M. Taube, Bernard A. Fox, Patrick Hwu, Igor Puzanov
miR-18a-5p derived from mesenchymal stem cells-extracellular vesicles inhibits ovarian cancer cell proliferation, migration, invasion, and chemotherapy resistance
Xiaoying Wang, Lili Jiang, Qifang Liu
Comparison of dynamic susceptibility contrast enhanced MR and FDG-PET brain studies in patients with Alzheimer’s disease and amnestic mild cognitive impairment
Aleksandra Wabik, Elżbieta Trypka, Joanna Bladowska, Mikołaj Statkiewicz, Marek Sąsiadek, Anna Zimny
Junctional adhesion molecule-like protein promotes tumor progression via the Wnt/β-catenin signaling pathway in lung adenocarcinoma
Qian Wu, Rui Li, Qing-Xiang Wang, Meng-Yu Zhang, Ting-Ting Liu, Yi-Qing Qu
Automated whole-slide images assessment of immune infiltration in resected non-small-cell lung cancer: towards better risk-stratification
Huan Lin, Xipeng Pan, Zhengyun Feng, Lixu Yan, Junjie Hua, Yanting Liang, Chu Han, Zeyan Xu, Yumeng Wang, Lin Wu, Yanfen Cui, Xiaomei Huang, Zhenwei Shi, Xin Chen, Xiaobo Chen, Qingling Zhang, Changhong Liang, Ke Zhao, Zhenhui Li, Zaiyi Liu
Stress-induced epinephrine promotes epithelial-to-mesenchymal transition and stemness of CRC through the CEBPB/TRIM2/P53 axis
Zili Zhou, Yan Shu, Haijun Bao, Shengbo Han, Zhengyi Liu, Ning Zhao, Wenzheng Yuan, Chenxing Jian, Xiaogang Shu
Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells
Domenica Scordamaglia, Francesca Cirillo, Marianna Talia, Maria Francesca Santolla, Damiano Cosimo Rigiracciolo, Lucia Muglia, Azzurra Zicarelli, Salvatore De Rosis, Francesca Giordano, Anna Maria Miglietta, Ernestina Marianna De Francesco, Veronica Vella, Antonino Belfiore, Rosamaria Lappano, Marcello Maggiolini
C2orf40 inhibits metastasis and regulates chemo-resistance and radio-resistance of nasopharyngeal carcinoma cells by influencing cell cycle and activating the PI3K/AKT/mTOR signaling pathway
Zuozhong Xie, Wei Li, Jingang Ai, Jun Xie, Xiaowei Zhang
Clinical applications of machine learning in the survival prediction and classification of sepsis: coagulation and heparin usage matter
Fei Guo, Xishun Zhu, Zhiheng Wu, Li Zhu, Jianhua Wu, Fan Zhang
Evaluation of the value of conventional and unconventional lipid parameters for predicting the risk of diabetes in a non-diabetic population
Guotai Sheng, Maobin Kuang, Ruijuan Yang, Yanjia Zhong, Shuhua Zhang, Yang Zou
Diagnostic potential of a circulating miRNA model associated with therapeutic effect in heart failure
Lu Qian, Qian Zhao, Ping Yu, Jinhui Lü, Yuefan Guo, Xin Gong, Yuanyuan Ding, Shanshan Yu, Lieying Fan, Huimin Fan, Yuzhen Zhang, Zhongmin Liu, Hongzhuan Sheng, Zuoren Yu
Treatments of chronic fatigue syndrome and its debilitating comorbidities: a 12-year population-based study
Kam-Hang Leong, Hei-Tung Yip, Chien-Feng Kuo, Shin-Yi Tsai
A dPCR-NIPT assay for detections of trisomies 21, 18 and 13 in a single-tube reaction-could it replace serum biochemical tests as a primary maternal plasma screening tool?
Peng Dai, Yanfeng Yang, Ganye Zhao, Zhiqiang Gu, Huanan Ren, Shuang Hu, Ning Liu, Weimeng Jiao, Jinfang Li, Xiangdong Kong
Neoadjuvant immunotherapy across cancers: meeting report from the Immunotherapy Bridge—December 1st–2nd, 2021
Elizabeth M. Burton, Rodabe N. Amaria, Tina Cascone, Myriam Chalabi, Neil D. Gross, Elizabeth A. Mittendorf, Richard A. Scolyer, Padmanee Sharma, Paolo A. Ascierto
Rationale and design of interleukin-1 blockade in recently decompensated heart failure (REDHART2): a randomized, double blind, placebo controlled, single center, phase 2 study
Benjamin Van Tassell, Virginia Mihalick, Georgia Thomas, Amr Marawan, Azita H. Talasaz, Juan Lu, Le Kang, Amy Ladd, Juan Ignacio Damonte, Dave L. Dixon, Roshanak Markley, Jeremy Turlington, Emily Federmann, Marco Giuseppe Del Buono, Giuseppe Biondi-Zoccai, Justin M. Canada, Ross Arena, Antonio Abbate
Multimodal data analysis reveals that pancreatobiliary-type ampullary adenocarcinoma resembles pancreatic adenocarcinoma and differs from cholangiocarcinoma
Jun Cheng, Yize Mao, Wenhui Hong, Wanming Hu, Peng Shu, Kun Huang, Jingjing Yu, Maofen Jiang, Liqin Li, Wei Wang, Dong Ni, Shengping Li
Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin
Hendrik Lintel, Darren B. Abbas, Christopher V. Lavin, Michelle Griffin, Jason L. Guo, Nicholas Guardino, Andrew Churukian, Geoffrey C. Gurtner, Arash Momeni, Michael T. Longaker, Derrick C. Wan
Combination of whole body cryotherapy with static stretching exercises reduces fatigue and improves functioning of the autonomic nervous system in Chronic Fatigue Syndrome
Sławomir Kujawski, Joanna Słomko, Beata R. Godlewska, Agnieszka Cudnoch-Jędrzejewska, Modra Murovska, Julia L. Newton, Łukasz Sokołowski, Paweł Zalewski
Identification of characteristic metabolic panels for different stages of prostate cancer by 1H NMR-based metabolomics analysis
Xi Zhang, Binbin Xia, Hong Zheng, Jie Ning, Yinjie Zhu, Xiaoguang Shao, Binrui Liu, Baijun Dong, Hongchang Gao
Treatment with eFT-508 increases chemosensitivity in breast cancer cells by modulating the tumor microenvironment
Zhao-ying Yang, Cheng-wei Jiang, Wen-long Zhang, Guang Sun
Comprehensive analysis of microglia gene and subpathway signatures for glioma prognosis and drug screening: linking microglia to glioma
Chunlong Zhang, Jiaxin Zhao, Wanqi Mi, Yuxi Zhang, Xiaoling Zhong, Guiyuan Tan, Feng Li, Xia Li, Yanjun Xu, Yunpeng Zhang
Secretion of miRNA-326-3p by senescent adipose exacerbates myocardial metabolism in diabetic mice
Hao Lin, Xiaonan Chen, Jianan Pan, Jiahan Ke, Alian Zhang, Yangyang Liu, Changqian Wang, Alex Chia Yu Chang, Jun Gu
Advances of exosomes in periodontitis treatment
Hongbing Lin, Huishan Chen, Xuetao Zhao, Tong Ding, Yawei Wang, Zhen Chen, Yue Tian, Peipei Zhang, Yuqin Shen
Blocking TIGIT/CD155 signalling reverses CD8+ T cell exhaustion and enhances the antitumor activity in cervical cancer
Lu Liu, Aihong Wang, Xiaoli Liu, Sai Han, Yu Sun, Junhua Zhang, Lingyu Guo, Youzhong Zhang
The treatment of Qibai Pingfei Capsule on chronic obstructive pulmonary disease may be mediated by Th17/Treg balance and gut-lung axis microbiota
Yu Jia, Tiantian He, Di Wu, Jiabing Tong, Jie Zhu, Zegeng Li, Jingcheng Dong
Correction: Cross validated serum small extracellular vesicle microRNAs for the detection of oropharyngeal squamous cell carcinoma
G. C. Mayne, C. M. Woods, N. Dharmawardana, T. Wang, S. Krishnan, J. C. Hodge, A. Foreman, S. Boase, A. S. Carney, E. A. W. Sigston, D. I. Watson, E. H. Ooi, D. J. Hussey
Molecular remodeling of adipose tissue is associated with metabolic recovery after weight loss surgery
Annie Bouchard-Mercier, Juan de Toro-Martín, Mélanie Nadeau, Odette Lescelleur, Stéfane Lebel, Denis Richard, Laurent Biertho, André Tchernof, Marie-Claude Vohl
Exosome-mediated lncRNA SND1-IT1 from gastric cancer cells enhances malignant transformation of gastric mucosa cells via up-regulating SNAIL1
Guohua Jin, Jianguang Zhang, Tingting Cao, Bang Chen, Yu Tian, Yang Shi
An N-glycoproteomic site-mapping analysis reveals glycoprotein alterations in esophageal squamous cell carcinoma
Yingzhen Gao, Liuyi Shen, Tianyue Dong, Xin Yang, Heyang Cui, Yanlin Guo, Yanchun Ma, Pengzhou Kong, Xiaolong Cheng, Ling Zhang, Yongping Cui
Combined treatment with inhibitors of ErbB Receptors and Hh signaling pathways is more effective than single treatment in reducing the growth of malignant mesothelioma both in vitro and in vivo
Roberto Bei, Monica Benvenuto, Chiara Focaccetti, Sara Fazi, Marta Moretti, Daniela Nardozi, Valentina Angiolini, Sara Ciuffa, Loredana Cifaldi, Raffaele Carrano, Camilla Palumbo, Martino Tony Miele, Riccardo Bei, Giovanni Barillari, Vittorio Manzari, Enrico De Smaele, Andrea Modesti, Laura Masuelli
A feedback loop between GATA2-AS1 and GATA2 promotes colorectal cancer cell proliferation, invasion, epithelial-mesenchymal transition and stemness via recruiting DDX3X
Yuliang Pan, Yuxing Zhu, Jun Zhang, Long Jin, Peiguo Cao
Epigenetic DNA methylation of Zbtb7b regulates the population of double-positive CD4+CD8+ T cells in ulcerative colitis
Hao-ming Xu, Jing Xu, Mei-feng Yang, Yu-jie Liang, Quan-zhou Peng, Yuan Zhang, Cheng-mei Tian, Yu-qiang Nie, Li-sheng Wang, Jun Yao, De-feng Li
Tumor-suppressive MEG3 induces microRNA-493-5p expression to reduce arabinocytosine chemoresistance of acute myeloid leukemia cells by downregulating the METTL3/MYC axis
Airong Wang, Yufei Chen, Luyao Shi, Mengya Li, Lingling Li, Shujuan Wang, Chong Wang
Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models
Stefania Cocco, Alessandra Leone, Maria Serena Roca, Rita Lombardi, Michela Piezzo, Roberta Caputo, Chiara Ciardiello, Susan Costantini, Francesca Bruzzese, Maria José Sisalli, Alfredo Budillon, Michelino De Laurentiis
Role of exosomes in the pathogenesis, diagnosis, and treatment of central nervous system diseases
Yishu Fan, Zhuohui Chen, Mengqi Zhang
Correction: Potential benefit of osimertinib plus bevacizumab in leptomeningeal metastasis with EGFR mutant non-small-cell lung cancer
Yali Yi, Jing Cai, Peng Xu, Le Xiong, Zhiqin Lu, Zhimin Zeng, Anwen Liu
Improve individual treatment by comparing treatment benefits: cancer artificial intelligence survival analysis system for cervical carcinoma
Jieyi Liang, Tingshan He, Hong Li, Xueqing Guo, Zhiqiao Zhang
Rhubarb free anthraquinones improved mice nonalcoholic fatty liver disease by inhibiting NLRP3 inflammasome
Chao Wu, Yanqin Bian, Bingjie Lu, Dan Wang, Nisma Lena Bahaji Azami, Gang Wei, Feng Ma, Mingyu Sun
Aberrant SPOP-CHAF1A ubiquitination axis triggers tumor autophagy that endows a therapeutical vulnerability in diffuse large B cell lymphoma
Wei Yan, Xue Shi, Huihan Wang, Aijun Liao, Wei Yang
The methyltransferase METTL3 promotes tumorigenesis via mediating HHLA2 mRNA m6A modification in human renal cell carcinoma
Dawei Zhu, Yingting Liu, Junjun Chen, Qi Wang, Yuan Li, Yulan Zhu, Jun Feng, Jingting Jiang
Homoharringtonine is synergistically lethal with BCL-2 inhibitor APG-2575 in acute myeloid leukemia
Wenwen Wei, Shujuan Huang, Qing Ling, Shihui Mao, Yu Qian, Wenle Ye, Fenglin Li, Jiajia Pan, Xiangjie Lin, Jiansong Huang, Xin Huang, Yifan Zhai, Jie Sun, Jie Jin
Autophagy activation mediates resistance to FLT3 inhibitors in acute myeloid leukemia with FLT3-ITD mutation
Dan Xu, Yishan Chen, Ying Yang, Zhao Yin, Changfen Huang, Qiang Wang, Ling Jiang, Xuejie Jiang, Changxin Yin, Qifa Liu, Guopan Yu
Emerging role of human microbiome in cancer development and response to therapy: special focus on intestinal microflora
Hourieh Sadrekarimi, Zhanna R. Gardanova, Morteza Bakhshesh, Farnoosh Ebrahimzadeh, Amirhossein Fakhre Yaseri, Lakshmi Thangavelu, Zahra Hasanpoor, Firoozeh Abolhasani Zadeh, Mohammad Saeed Kahrizi
Spatial transcriptomics atlas reveals the crosstalk between cancer-associated fibroblasts and tumor microenvironment components in colorectal cancer
Zhiwei Peng, Manping Ye, Huiming Ding, Zhenyou Feng, Kongwang Hu
eIF6 is potential diagnostic and prognostic biomarker that associated with 18F-FDG PET/CT features and immune signatures in esophageal carcinoma
Yan Gao, Lingling Yuan, Jing Zeng, Fuyan Li, Xiaohui Li, Fan Tan, Xusheng Liu, Huabing Wan, Xueyan Kui, Xiaoyu Liu, Changbin Ke, Zhijun Pei
SEMA4D/PlexinB1 promotes AML progression via activation of PI3K/Akt signaling
Lu Liu, Lin Yang, Xiaojun Liu, Menghan Liu, Jing Liu, Xuefeng Feng, Ziyuan Nie, Jianmin Luo
Rhein attenuates angiotensin II-induced cardiac remodeling by modulating AMPK–FGF23 signaling
Wei Lu, Hongqiao Zhu, Jiawen Wu, Sheng Liao, Guobing Cheng, Xiaoyang Li
Identification of functional pathways and molecular signatures in neuroendocrine neoplasms by multi-omics analysis
Viola Melone, Annamaria Salvati, Domenico Palumbo, Giorgio Giurato, Giovanni Nassa, Francesca Rizzo, Luigi Palo, Alessandro Giordano, Mariarosaria Incoronato, Mario Vitale, Caterina Mian, Immacolata Di Biase, Stefano Cristiano, Viviana Narciso, Monica Cantile, Annabella Di Mauro, Fabiana Tatangelo, Salvatore Tafuto, Roberta Modica, Claudia Pivonello, Marco Salvatore, Annamaria Colao, Alessandro Weisz, Roberta Tarallo
Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy
Jingsong Cao, Cong Chen, Qian Chen, Yan Gao, Zhibo Zhao, Qing Yuan, Anqi Li, Shiqi Yang, Yuqi He, Xuyu Zu, Jianghua Liu
Bladder cancer-derived exosomal KRT6B promotes invasion and metastasis by inducing EMT and regulating the immune microenvironment
Qiang Song, Hao Yu, Yidong Cheng, Jie Han, Kai Li, Juntao Zhuang, Qiang Lv, Xiao Yang, Haiwei Yang
Low potassium disrupt intestinal barrier and result in bacterial translocation
Haishan Wu, Rong Huang, Jinjin Fan, Ning Luo, Xiao Yang
Syringin exerts anti-breast cancer effects through PI3K-AKT and EGFR-RAS-RAF pathways
Fei Wang, Chong Yuan, Bo Liu, Yan-Fang Yang, He-Zhen Wu
Molecular dissection of a hyper-aggressive CBFB-MYH11/FLT3-ITD–positive acute myeloid leukemia
Gabriele Lo Iudice, Eleonora De Bellis, Arianna Savi, Luca Guarnera, Alice Massacci, Francesca De Nicola, Frauke Goeman, Tiziana Ottone, Mariadomenica Divona, Matteo Pallocca, Maurizio Fanciulli, Maria Teresa Voso, Gennaro Ciliberto
Oral ecological environment modifications by hard-cheese: from pH to microbiome: a prospective cohort study based on 16S rRNA metabarcoding approach
Erna Cecilia Lorenzini, Barbara Lazzari, Gianluca Martino Tartaglia, Giampietro Farronato, Valentina Lanteri, Sara Botti, Filippo Biscarini, Paolo Cozzi, Alessandra Stella
SLC26A4 correlates with homologous recombination deficiency and patient prognosis in prostate cancer
Cong Luo, Zhi Liu, Yu Gan, Xiaomei Gao, Xiongbing Zu, Ye Zhang, Wenrui Ye, Yi Cai
Potential inhibitors for blocking the interaction of the coronavirus SARS-CoV-2 spike protein and its host cell receptor ACE2
Changzhi Li, Hongjuan Zhou, Lingling Guo, Dehuan Xie, Huiping He, Hong Zhang, Yixiu Liu, Lixia Peng, Lisheng Zheng, Wenhua Lu, Yan Mei, Zhijie Liu, Jie Huang, Mingdian Wang, Ditian Shu, Liuyan Ding, Yanhong Lang, Feifei Luo, Jing Wang, Bijun Huang, Peng Huang, Song Gao, Jindong Chen, Chao-Nan Qian
Identification of ENO1 as a prognostic biomarker and molecular target among ENOs in bladder cancer
Zhengnan Huang, Yilin Yan, Tengjiao Wang, Zeyi Wang, Jinming Cai, Xiangqian Cao, Chenkai Yang, Fang Zhang, Gang Wu, Bing Shen
Molecular mimicry between tumor associated antigens and microbiota-derived epitopes
Concetta Ragone, Carmen Manolio, Angela Mauriello, Beatrice Cavalluzzo, Franco M. Buonaguro, Maria Lina Tornesello, Maria Tagliamonte, Luigi Buonaguro
Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
Åslaug Helland, Hege G. Russnes, Gro Live Fagereng, Khalid Al-Shibli, Yvonne Andersson, Thomas Berg, Line Bjørge, Egil Blix, Bodil Bjerkehagen, Sigmund Brabrand, Marte Grønlie Cameron, Astrid Dalhaug, Dalia Dietzel, Tom Dønnem, Espen Enerly, Åsmund Flobak, Sverre Fluge, Bjørnar Gilje, Bjørn Tore Gjertsen, Bjørn Henning Grønberg, Kari Grønås, Tormod Guren, Hanne Hamre, Åse Haug, Daniel Heinrich, Geir Olav Hjortland, Eivind Hovig, Randi Hovland, Ann-Charlotte Iversen, Emiel Janssen, Jon Amund Kyte, Hedda von der Lippe Gythfeldt, Ragnhild Lothe, Jo-Åsmund Lund, Leonardo Meza-Zepeda, Monica Cheng Munthe-Kaas, Olav Toai Duc Nguyen, Pitt Niehusmann, Hilde Nilsen, Katarina Puco, Anne Hansen Ree, Tonje Bøyum Riste, Karin Semb, Eli Sihn Samdal Steinskog, Andreas Stensvold, Pål Suhrke, Øyvind Tennøe, Geir E. Tjønnfjord, Liv Jorunn Vassbotn, Eline Aas, Kristine Aasebø, Kjetil Tasken, Sigbjørn Smeland
A reduction of Syndecan-4 in macrophages promotes atherosclerosis by aggravating the proinflammatory capacity of macrophages
Jiaxin Hu, Ying Zhang, Liaoping Hu, Haiting Chen, Han Wu, Jianzhou Chen, Jun Xie, Biao Xu, Zhonghai Wei
TA-MSCs, TA-MSCs-EVs, MIF: their crosstalk in immunosuppressive tumor microenvironment
Zhenghou Zhang, Xiangyu Zhou, Jinshuai Guo, Fusheng Zhang, Yiping Qian, Guang Wang, Meiqi Duan, Yutian Wang, Haiying Zhao, Zhi Yang, Zunpeng Liu, Xiaofeng Jiang
The abnormal expression of circ-ARAP2 promotes ESCC progression through regulating miR-761/FOXM1 axis-mediated stemness and the endothelial–mesenchymal transition
Pei Xu, Lei Wang, Qingtao Liu, Pengkai Gao, Fengqing Hu, Xiao Xie, Lianyong Jiang, Rui Bi, Fangbao Ding, Qi Yang, Haibo Xiao
Identifying patterns of immune related cells and genes in the peripheral blood of acute myocardial infarction patients using a small cohort
Peng-Fei Zheng, Qiong-Chao Zou, Lu-Zhu Chen, Peng Liu, Zheng-Yu Liu, Hong-Wei Pan
Interplay of Helicobacter pylori, fibroblasts, and cancer cells induces fibroblast activation and serpin E1 expression by cancer cells to promote gastric tumorigenesis
Xueshu Chen, Wei Chen, Yan Zhao, Qinrong Wang, Wenling Wang, Yining Xiang, Hang Yuan, Yuan Xie, Jianjiang Zhou
Transplanted allogeneic cardiac progenitor cells secrete GDF-15 and stimulate an active immune remodeling process in the ischemic myocardium
Rachana Mishra, Progyaparamita Saha, Srinivasa Raju Datla, Pranav Mellacheruvu, Muthukumar Gunasekaran, Sameer Ahmad Guru, Xuebin Fu, Ling Chen, Roberto Bolli, Sudhish Sharma, Sunjay Kaushal
Whole-exome sequencing identified mutational profiles of urothelial carcinoma post kidney transplantation
Lee-Moay Lim, Wen-Yu Chung, Daw-Yang Hwang, Chih-Chuan Yu, Hung-Lung Ke, Peir-In Liang, Ting-Wei Lin, Siao Muk Cheng, A-Mei Huang, Hung-Tien Kuo
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN
Rongguiyi Zhang, Jiyuan Ai, Jiakun Wang, Chi sun, Hongcheng Lu, Aoxiao He, Min Li, Yuting Liao, Jun Lei, Fan Zhou, Linquan Wu, Wenjun Liao
Engineered exosome-mediated delivery of circDIDO1 inhibits gastric cancer progression via regulation of MiR-1307-3p/SOCS2 Axis
Zhen Guo, Yu Zhang, Wenrong Xu, Xu Zhang, Jiajia Jiang
Forkhead Box S1 mediates epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway to regulate colorectal cancer progression
Liang Zhang, Chuan-fu Ren, Zhi Yang, Long-bo Gong, Chao Wang, Min Feng, Wen-xian Guan
Immunotherapy landscape analyses of necroptosis characteristics for breast cancer patients
Honghao Yu, Wenchang Lv, Yufang Tan, Xiao He, Yiping Wu, Min Wu, Qi Zhang
Establishment of a piglet model for peritoneal metastasis of ovarian cancer
Eun Ji Lee, Soo Jin Park, Aeran Seol, Hyunji Lim, Sumin Park, Ji Yeon Ahn, Jeong Mook Lim, Hee Seung Kim, Ji Won Park, Gwonhwa Song, Jiyen Ham, Sunwoo Park, Ga Won Yim, Seung-Hyuk Shim, Beong-Cheol Kang, Suk Joon Chang, Whasun Lim, Jung Chan Lee
Glutamine deficiency promotes recurrence and metastasis in colorectal cancer through enhancing epithelial–mesenchymal transition
Hongyan Sun, Chuan Zhang, Yang Zheng, Chenlu Liu, Xue Wang, Xianling Cong
Co-expression of TNF receptors 1 and 2 on melanomas facilitates soluble TNF-induced resistance to MAPK pathway inhibitors
Cindy A. Sander, Elizabeth A. Rush, Jian Shi, Lidia M. R. B. Arantes, Raymond J. Tesi, Mark A. Ross, Michael J. Calderon, Simon C. Watkins, John M. Kirkwood, Robert L. Ferris, Lisa H. Butterfield, Lazar Vujanovic
A novel immune checkpoints-based signature to predict prognosis and response to immunotherapy in lung adenocarcinoma
Nan Sun, Yuejun Luo, Bo Zheng, Zhihui Zhang, Chaoqi Zhang, Zhen Zhang, Guochao Zhang, Fengwei Tan, Qi Xue, Shugeng Gao, Jie He
Effects of different potassium-lowering regimens on acute hyperkalemia in hemodialysis patients: a real-world, retrospective study
Lan Yao, Xiaoyang Xing, Yubao Li, Fangxing Zhang, Ping Li, Xianhui Liang, Pei Wang
RGS1 and related genes as potential targets for immunotherapy in cervical cancer: computational biology and experimental validation
Siyang Zhang, Han Wang, Jiao Liu, Tao Tao, Zhi Zeng, Min Wang
The BRD4 inhibitor JQ1 suppresses tumor growth by reducing c-Myc expression in endometrial cancer
Yingxin Pang, Gaigai Bai, Jing Zhao, Xuan Wei, Rui Li, Jie Li, Shunxue Hu, Lu Peng, Peishu Liu, Hongluan Mao
Asprosin inhibits macrophage lipid accumulation and reduces atherosclerotic burden by up-regulating ABCA1 and ABCG1 expression via the p38/Elk-1 pathway
Jin Zou, Can Xu, Zhen-Wang Zhao, Shan-Hui Yin, Gang Wang
Sex hormones and physical function among the Chinese oldest-old and centenarian women
Qiao Zhu, Ping Ping, Pei Zhang, Chaoxue Ning, Yali Zhao, Yao Yao, Xiubing Li, Shihui Fu
Prognostic and predictive value of radiomic signature in stage I lung adenocarcinomas following complete lobectomy
Wei Nie, Guangyu Tao, Zhenghai Lu, Jie Qian, Yaqiong Ge, Shuyuan Wang, Xueyan Zhang, Hua Zhong, Hong Yu
Identification of genomic determinants contributing to cytokine release in immunotherapies and human diseases
Lipei Shao, Alejandra Pelayo, Rongye Shi, Jinxia Ma, Hui Liu, Yihua Cai, Michaela Prochazkova, Robert P. Somerville, Sandhya R. Panch, Nirali N. Shah, David F. Stroncek, Ping Jin
Reducing VEGFB accelerates NAFLD and insulin resistance in mice via inhibiting AMPK signaling pathway
Rongrong Li, Yuqi Li, Xueling Yang, Yaorui Hu, Haining Yu, Yana Li
Modulation of hepatic stellate cells by Mutaflor® probiotic in non-alcoholic fatty liver disease management
Noha M. Hany, Sanaa Eissa, Manal Basyouni, Amany H. Hasanin, Yasmin M. Aboul-Ela, Nagwa M. Abo Elmagd, Iman F. Montasser, Mahmoud A. Ali, Paul J. Skipp, Marwa Matboli
The RNA-binding protein PCBP1 represses lung adenocarcinoma progression by stabilizing DKK1 mRNA and subsequently downregulating β-catenin
Yujia Zheng, Zheng Zhou, Ran Wei, Chu Xiao, Hao Zhang, Tao Fan, Bo Zheng, Chunxiang Li, Jie He
Associations between dietary fiber intake and mortality from all causes, cardiovascular disease and cancer: a prospective study
Xin Xu, Junmiao Zhang, Yanhui Zhang, Honggang Qi, Ping Wang
A fetal fraction enrichment method reduces false negatives and increases test success rate of fetal chromosome aneuploidy detection in early pregnancy loss
Longwei Qiao, Bin Zhang, Xiaojuan Wu, Chunhua Zhang, Ying Xue, Hui Tang, Haoyu Tang, Jingye Shi, Yuting Liang, Bin Yu, Ting Wang
Exosomes derived from myeloid-derived suppressor cells facilitate castration-resistant prostate cancer progression via S100A9/circMID1/miR-506-3p/MID1
Feng Gao, Qiaoping Xu, Zhe Tang, Nan Zhang, Yasheng Huang, Zhongyi Li, Yuliang Dai, Qiqi Yu, Jingyu Zhu
IDO/kynurenine pathway in cancer: possible therapeutic approaches
Eslam E. Abd El-Fattah
IGF2BP1-regulated expression of ERRα is involved in metabolic reprogramming of chemotherapy resistant osteosarcoma cells
Qing He, Peng Hao, Gang He, Hantao Mai, Wenzhou Liu, Weiqiong Zhang, Kelin Zhang, Guifang Zhong, Ruilian Guo, Changzhi Yu, Yang Li, Chipiu Wong, Qian Chen, Yantao Chen
Non-coding RNAs in lung cancer: emerging regulators of angiogenesis
Yajie Liao, Xudong Wu, Mengyu Wu, Yuan Fang, Jie Li, Weiqiang Tang
LINC00665 knockdown confers sensitivity in irradiated non-small cell lung cancer cells through the miR-582-5p/UCHL3/AhR axis
Li-Ming Xu, Ya-Jing Yuan, Hao Yu, Shuai Wang, Ping Wang
Harm of circadian misalignment to the hearts of the adolescent wistar rats
YunLei Wang, YuanYuan Hou, ShaoFei Song, Yao Zuo, Yan Yu, YaFei Chi, Tong Zhang
Interrelationships and determinants of aging biomarkers in cord blood
Brigitte Reimann, Dries S. Martens, Congrong Wang, Akram Ghantous, Zdenko Herceg, Michelle Plusquin, Tim S. Nawrot
Fecal microbiota transplantation versus glucocorticoids for the induction of remission in mild to moderate ulcerative colitis
Chunlan Huang, Zehua Huang, Ling Ding, Yang Fu, Junjie Fan, Qixiang Mei, Lihong Lou, Jingjing Wang, Nuoming Yin, Yingying Lu, Sanwei Guo, Yue Zeng
Identification of LARS as an essential gene for osteosarcoma proliferation through large-Scale CRISPR-Cas9 screening database and experimental verification
Wenhao Chen, Yuxiang Lin, Meichen Jiang, Qingshui Wang, Qiang Shu
LncRNA GAS6-AS1 facilitates tumorigenesis and metastasis of colorectal cancer by regulating TRIM14 through miR-370-3p/miR-1296-5p and FUS
Qing Chen, Lin Zhou, De Ma, Juan Hou, Yuxin Lin, Jie Wu, Min Tao
Zishen pingchan granules combined with pramipexole in the improvement of depressive symptoms in Parkinson's disease: a prospective, multicenter, randomized, double-blind, controlled clinical study
Houxu Ning, Hao Zhou, Jingru Ren, Gaiyan Zhou, Ning Yang, Zhenfu Wang, Canxing Yuan, Zuojun Tian, Juping Chen, Lihua Shen, Huifen Zheng, Yang Zhao, Haidong Wang, Weiguo Liu, Zhenguo Liu
Advances in nuclear medicine-based molecular imaging in head and neck squamous cell carcinoma
Danni Li, Xuran Li, Jun Zhao, Fei Tan
Integration of CD34+CD117dim population signature improves the prognosis prediction of acute myeloid leukemia
Xue-Ping Li, Wei-Na Zhang, Jia-Ying Mao, Bai-Tian Zhao, Lu Jiang, Yan Gao
Germline genetic biomarkers to stratify patients for personalized radiation treatment
Ida Deichaite, Austin Hopper, Lena Krockenberger, Timothy J. Sears, Leisa Sutton, Xenia Ray, Andrew Sharabi, Ami Navon, Parag Sanghvi, Hannah Carter, Vitali Moiseenko
Identification of immune-related key genes in the peripheral blood of ischaemic stroke patients using a weighted gene coexpression network analysis and machine learning
Peng-Fei Zheng, Lu-Zhu Chen, Peng Liu, Hong Wei Pan, Wen-Juan Fan, Zheng-Yu Liu
Comprehensive characterization of clonality of driver genes revealing their clinical relevance in colorectal cancer
Jian Shi, Li Wang, Xiangzhe Yin, Lixia Wang, Lin Bo, Kailai Liu, Ke Feng, Shihua Lin, Yanjun Xu, Shangwei Ning, Hongying Zhao
Evidence of pyroptosis and ferroptosis extensively involved in autoimmune diseases at the single-cell transcriptome level
Danfeng Zhang, Yadan Li, Chunyan Du, Lina Sang, Liu Liu, Yingmei Li, Fang Wang, Wenjuan Fan, Ping Tang, Sidong Zhang, Dandan Chen, Yanmei Wang, Xiaoyi Wang, Xinsheng Xie, Zhongxing Jiang, Yongping Song, Rongqun Guo
Construction of a predictive model for immunotherapy efficacy in lung squamous cell carcinoma based on the degree of tumor-infiltrating immune cells and molecular typing
Lingge Yang, Shuli Wei, Jingnan Zhang, Qiongjie Hu, Wansong Hu, Mengqing Cao, Long Zhang, Yongfang Wang, Pingli Wang, Kai Wang
Molecular evolutionary process of advanced gastric cancer during sequential chemotherapy detected by circulating tumor DNA
Wenqi Xi, Chenfei Zhou, Fei Xu, Debin Sun, Shengzhou Wang, Yawei Chen, Jun Ji, Tao Ma, Junwei Wu, Chengfang Shangguan, Zhenggang Zhu, Jun Zhang
Correction to: Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis
Qi Chen, Xi Liang, Tianzhou Wu, Jing Jiang, Yongpo Jiang, Sheng Zhang, Yanyun Ruan, Huaping Zhang, Chao Zhang, Peng Chen, Yuhang Lv, Jiaojiao Xin, Dongyan Shi, Xin Chen, Jun Li, Yinghe Xu
Clinical features, molecular pathology, and immune microenvironmental characteristics of acral melanoma
Jianping Gui, Zhen Guo, Di Wu
Gene expression and methylation profiles show the involvement of POMC in primary hyperparathyroidsm
Wen-Xuan Zhou, Shu Wang, Ting-Chao Wu, Ling-Chao Cheng, Yao Du, Wei Wu, Chen Lin, Xin-Ying Li, Zhong-Liang Hu
Dual roles of interleukin-33 in cognitive function by regulating central nervous system inflammation
Xiuqin Rao, Fuzhou Hua, Lieliang Zhang, Yue Lin, Pu Fang, Shoulin Chen, Jun Ying, Xifeng Wang
Translation of the 27-gene immuno-oncology test (IO score) to predict outcomes in immune checkpoint inhibitor treated metastatic urothelial cancer patients
Robert S. Seitz, Michael E. Hurwitz, Tyler J. Nielsen, Daniel B. Bailey, Matthew G. Varga, Brian Z. Ring, Carrie F. Metts, Brock L. Schweitzer, Kimberly McGregor, Douglas T. Ross
The amount of DNA combined with TP53 mutations in liquid biopsy is associated with clinical outcome of renal cancer patients treated with immunotherapy and VEGFR-TKIs
Marzia Del Re, Stefania Crucitta, Federico Paolieri, Federico Cucchiara, Elena Verzoni, Francesco Bloise, Raffaele Ciampi, Chiara Mercinelli, Annalisa Capuano, Liberata Sportiello, Antonia Martinetti, Giuseppe Procopio, Luca Galli, Camillo Porta, Sergio Bracarda, Romano Danesi
Pregnancy loss and subsequent risk of prediabetes, diabetes and metabolic syndrome in couples: Tehran lipid and glucose study
Maryam Rahmati, Marzieh Saei Ghare Naz, Fereidoun Azizi, Fahimeh Ramezani Tehrani
Total mutational load and clinical features as predictors of the metastatic status in lung adenocarcinoma and squamous cell carcinoma patients
Karen Y. Oróstica, Juan Saez-Hidalgo, Pamela R. de Santiago, Solange Rivas, Sebastian Contreras, Gonzalo Navarro, Juan A. Asenjo, Álvaro Olivera-Nappa, Ricardo Armisén
Serum trimethylamine-N-oxide is associated with incident type 2 diabetes in middle-aged and older adults: a prospective cohort study
Shu-yi Li, Si Chen, Xiao-ting Lu, Ai-ping Fang, Yu-ming Chen, Rong-zhu Huang, Xin-lei Lin, Zi-hui Huang, Jing-fei Ma, Bi-xia Huang, Hui-lian Zhu
3'-[18F]fluoro-3'-deoxythymidine ([18F]FLT) Positron Emission Tomography as an In Vivo Biomarker of inhibition of CDK 4/6-Rb pathway by Palbociclib in a patient derived bladder tumor
James L. Tatum, Joseph D. Kalen, Paula M. Jacobs, Lisa A. Riffle, Amy James, Lai Thang, Chelsea Sanders, Melinda G. Hollingshead, Falguni Basuli, Jianfeng Shi, James H. Doroshow
Combined lifestyle, mental health, and mortality in US cancer survivors: a national cohort study
Zhao-yan Liu, Chen Wang, Yao-jun Zhang, Hui-lian Zhu
A new nutraceutical (Livogen Plus®) improves liver steatosis in adults with non-alcoholic fatty liver disease
Yvelise Ferro, Roberta Pujia, Elisa Mazza, Lidia Lascala, Oscar Lodari, Samantha Maurotti, Arturo Pujia, Tiziana Montalcini
Lkb1 aggravates diffuse large B-cell lymphoma by promoting the function of Treg cells and immune escape
Xiuhua Su, Tao Sun, Meng Li, Yuan Xia, Mingying Li, Dongmei Wang, Fei Lu, Jingjing Ye, Chunyan Ji
lncRNA-AC079061.1/VIPR1 axis may suppress the development of hepatocellular carcinoma: a bioinformatics analysis and experimental validation
Xia-Hui Lin, Dan-Ying Zhang, Zhi-Yong Liu, Wen-qing Tang, Rong-Xin Chen, Dong-ping Li, Shuqiang Weng, Ling Dong
Markers of endothelial glycocalyx dysfunction in Clarkson disease
Zhihui Xie, Magne Børset, Kjell Svéen, Ole Wilhelm Bøe, Eunice C. Chan, Justin B. Lack, Katherine M. Hornick, Franco Verlicchi, A. Robin Eisch, Remo Melchio, Arkadiusz Z. Dudek, Kirk M. Druey
Establishment and evaluation of ectopic and orthotopic prostate cancer models using cell sheet technology
Dongliang Zhang, Ying Wang, Lei Liu, Zeng Li, Shengke Yang, Weixin Zhao, Xiang Wang, Hong Liao, Shukui Zhou
Probiotics ameliorate IgA nephropathy by improving gut dysbiosis and blunting NLRP3 signaling
Jiaxing Tan, Lingqiu Dong, Zheng Jiang, Li Tan, Xinyao Luo, Gaiqin Pei, Aiya Qin, Zhengxia Zhong, Xiang Liu, Yi Tang, Wei Qin
Low mitochondrial DNA copy number induces chemotherapy resistance via epithelial-mesenchymal transition by DNA methylation in esophageal squamous cancer cells
Yuto Kubo, Koji Tanaka, Yasunori Masuike, Tsuyoshi Takahashi, Kotaro Yamashita, Tomoki Makino, Takuro Saito, Kazuyoshi Yamamoto, Tomoyuki Tsujimoto, Takashi Harino, Yukinori Kurokawa, Makoto Yamasaki, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki
SPOP promotes cervical cancer progression by inducing the movement of PD-1 away from PD-L1 in spatial localization
Jiangchun Wu, Yong Wu, Qinhao Guo, Siyu chen, Simin Wang, Xiaohua Wu, Jun Zhu, Xingzhu Ju
Gene signatures, immune infiltration, and drug sensitivity based on a comprehensive analysis of m6a RNA methylation regulators in cervical cancer
Xiaoqin Lu, Rui Li, Yanqi Ying, Wenyi Zhang, Wuliang Wang
Association of peripheral basophils with tumor M2 macrophage infiltration and outcomes of the anti-PD-1 inhibitor plus chemotherapy combination in advanced gastric cancer
Chaorui Wu, Yaopeng Qiu, Renyi Zhang, Xiaoqing Li, Huayuan Liang, Minghao Wang, Fengping Li, Mansheng Zhu, Gengtai Ye, Hao Liu, Guoxin Li, Liying Zhao
Salivary microbiome in chronic kidney disease: what is its connection to diabetes, hypertension, and immunity?
Fengping Liu, Jiayi Sheng, Lei Hu, Bin Zhang, Wei Guo, Yang Wang, Yifeng Gu, Peng Jiang, Hao Lin, Brako Lydia, Yifan Sun, Yifan Tang, Chaoqun Gu, Shichao Wei, Qixiao Zhai, Weiguo Chen, Ninghan Feng
Radiated glioblastoma cell-derived exosomal circ_0012381 induce M2 polarization of microglia to promote the growth of glioblastoma by CCL2/CCR2 axis
Chunzhi Zhang, Yuan Zhou, Ya Gao, Ze Zhu, Xianliang Zeng, Weizi Liang, Songwei Sun, Xiuli Chen, Hu Wang
In silico designing of a novel epitope-based candidate vaccine against Streptococcus pneumoniae with introduction of a new domain of PepO as adjuvant
Zohreh Bahadori, Mona Shafaghi, Hamid Madanchi, Mohammad Mehdi Ranjbar, Ali Akbar Shabani, Seyed Fazlollah Mousavi
RET fusions as primary oncogenic drivers and secondary acquired resistance to EGFR tyrosine kinase inhibitors in patients with non-small-cell lung cancer
Chunyue Wang, Zhenlong Zhang, Yulan Sun, Song Wang, Mengmeng Wu, Qiuxiang Ou, Yang Xu, Zhiming Chen, Yang Shao, Hong Liu, Peifeng Hou
Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd – 4th, 2021, Italy)
Paolo A. Ascierto, Sanjiv S. Agarwala, Christian Blank, Corrado Caracò, Richard D. Carvajal, Marc S. Ernstoff, Soldano Ferrone, Bernard A. Fox, Thomas F. Gajewski, Claus Garbe, Jean-Jacques Grob, Omid Hamid, Michelle Krogsgaard, Roger S. Lo, Amanda W. Lund, Gabriele Madonna, Olivier Michielin, Bart Neyns, Iman Osman, Solange Peters, Poulikos I. Poulikakos, Sergio A. Quezada, Bradley Reinfeld, Laurence Zitvogel, Igor Puzanov, Magdalena Thurin
Lumican is elevated in the lung in human and experimental acute respiratory distress syndrome and promotes early fibrotic responses to lung injury
Ke Wang, Youyu Wang, Yufang Cao, Hao Wang, Yongfang Zhou, Lijuan Gao, Zijian Zeng, Mengxin Cheng, Xiaodong Jin, Jun Chen, Fuqiang Wen, Tao Wang
The potential of mecciRNA in hepatic stellate cell to regulate progression of nonalcoholic hepatitis
Boqiang Liu, Yuanshi Tian, Jing He, Qiuxia Gu, Binghan Jin, Hao Shen, Weiqi Li, Liang Shi, Hong Yu, Ge Shan, Xiujun Cai
Heme oxygenase 1 overexpression induces immune evasion of acute myeloid leukemia against natural killer cells by inhibiting CD48
Tianzhuo Zhang, Qin Fang, Ping Liu, Ping Wang, Cheng Feng, Jishi Wang
circCRKL, a circRNA derived from CRKL, regulates BCR-ABL via sponging miR-877-5p to promote chronic myeloid leukemia cell proliferation
Jianming Wang, Yang Liang, Yuefeng Qin, Guoyun Jiang, Yuhang Peng, Wenli Feng
Non-invasive preimplantation genetic testing for conventional IVF blastocysts
Pingyuan Xie, Shuoping Zhang, Yifang Gu, Bo Jiang, Liang Hu, Yue-qiu Tan, Yaxin Yao, Yi Tang, Anqi Wan, Sufen Cai, Yangyun Zou, Guangxiu Lu, Cheng Wan, Fei Gong, Sijia Lu, Ge Lin
Effects of a 4400 km ultra-cycling non-competitive race and related training on body composition and circulating progenitors differentiation
Maria Teresa Valenti, Michele Braggio, Arianna Minoia, Gianluigi Dorelli, Jessica Bertacco, Francesco Bertoldo, Mattia Cominacini, Tonia De Simone, Maria Grazia Romanelli, Lekhana Bhandary, Monica Mottes, Luca Dalle Carbonare
The triglyceride glucose-body mass index: a non-invasive index that identifies non-alcoholic fatty liver disease in the general Japanese population
Haofei Hu, Yong Han, Changchun Cao, Yongcheng He
Identification of diagnostic biomarkers and therapeutic targets in peripheral immune landscape from coronary artery disease
Xiaoteng Feng, Yifan Zhang, Min Du, Sijin Li, Jie Ding, Jiarou Wang, Yiru Wang, Ping Liu
Vascular endothelial growth factor and its receptors regulation in gestational diabetes mellitus and eclampsia
Alayi Bolatai, Yujing He, Na Wu
Effect of Omega-3 fatty acids supplementation on serum level of C-reactive protein in patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials
Amira Mohamed Taha, Ahmad Shehata Shaarawy, Mohamed Mosad Omar, Khaled Abouelmagd, Noran Magdy Shalma, Mais Alhashemi, Hala Mahmoud Ahmed, Ahmed Hafez Allam, Mohamed Abd-ElGawad
Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer
Zhan Wang, Miao-Miao Wang, Yan Geng, Chen-Yang Ye, Yuan-Sheng Zang
Higher polygenic risk for melanoma is associated with improved survival in a high ultraviolet radiation setting
Mathias Seviiri, Richard A. Scolyer, D. Timothy Bishop, Julia A. Newton-Bishop, Mark M. Iles, Serigne N. Lo, Johnathan R. Stretch, Robyn P. M. Saw, Omgo E. Nieweg, Kerwin F. Shannon, Andrew J. Spillane, Scott D. Gordon, Catherine M. Olsen, David C. Whiteman, Maria Teresa Landi, John F. Thompson, Georgina V. Long, Stuart MacGregor, Matthew H. Law
The potential applications of microparticles in the diagnosis, treatment, and prognosis of lung cancer
Yu Liu, Sufei Wang, Hui Xia, Xueyun Tan, Siwei Song, Shujing Zhang, Daquan Meng, Qing Chen, Yang Jin
Association between postoperative radiotherapy for young-onset head and neck cancer and long-term risk of second primary malignancy: a population-based study
Xiaoke Zhu, Jian Zhou, Liang Zhou, Ming Zhang, Chunli Gao, Lei Tao
11β-HSD1 participates in epileptogenesis and the associated cognitive impairment by inhibiting apoptosis in mice
Xueying Li, Wanhua Qiu, Lu Deng, Jingjing Lin, Wenting Huang, Yuchen Xu, Mulan Zhang, Nigel C. Jones, Runxuan Lin, Huiqin Xu, Li Lin, Peijun Li, Xinshi Wang
Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation
Hongting Hao, Sen Yan, Xinbo Zhao, Xuejie Han, Ning Fang, Yun Zhang, Chenguang Dai, Wenpeng Li, Hui Yu, Yunlong Gao, Dingyu Wang, Qiang Gao, Yu Duan, Yue Yuan, Yue Li
Pathogenic somatic alterations of DDR genes in lung cancer are significantly different from germline mutations and are associated with more unstable genomes
Huaqing Wang, Yue Zhao, Fei Wang, Xiaofeng Zhu, Ningning Luo, Tingting Sun, Chuang Qi, Xin Li
Global research trends and foci of artificial intelligence-based tumor pathology: a scientometric study
Zefeng Shen, Jintao Hu, Haiyang Wu, Zeshi Chen, Weixia Wu, Junyi Lin, Zixin Xu, Jianqiu Kong, Tianxin Lin
Identification and analysis of mitochondria-related key genes of heart failure
Haozhen Yu, Mujun Yu, Zhuang Li, Enhu Zhang, Heng Ma
Longitudinal assessment of systemic steroid therapy on hyperinflammatory endothelial biomarker profiles and serology responses of COVID-19 patients
Jonathan T. Sims, Ching-Yun Chang, Josh Poorbaugh, Montanea Daniels, Stephanie L. Beasley, Lin Zhang, George H. Rodgers, Fabio Lena, Leonardo G. Lacerenza, Bruno Sposato, Annabelle Dupont, Sophie Susen, Giacomo Casalini, Mario Corbellino, Justin Stebbing, Venkatesh Krishnan
Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia
Yuting Chen, Kaipeng Li, Han Zhao, Zhangsen Hao, Yuxin Yang, Mingming Gao, Ding Zhao
Small and long RNA transcriptome of whole human cerebrospinal fluid and serum as compared to their extracellular vesicle fractions reveal profound differences in expression patterns and impacts on biological processes
Uwe Michel, Orr Shomroni, Barbara Müller, Peter Lange, Gabriela Salinas, Mathias Bähr, Jan Christoph Koch
TSLP promoting B cell proliferation and polarizing follicular helper T cell as a therapeutic target in IgG4-related disease
Hui Lu, Xunyao Wu, Yu Peng, Ruijie Sun, Yuxue Nie, Jingna Li, Mu Wang, Yaping Luo, Linyi Peng, Yunyun Fei, Jiaxin Zhou, Wen Zhang, Xiaofeng Zeng
A humanized 4-1BB-targeting agonistic antibody exerts potent antitumor activity in colorectal cancer without systemic toxicity
Lian-sheng Cheng, Yong-feng Cheng, Wen-ting Liu, Aolin Shen, Dayan Zhang, Tingjuan Xu, Wu Yin, Min Cheng, Xiaopeng Ma, Fengrong Wang, Qun Zhao, Xiaoli Zeng, Yan Zhang, Guodong Shen
From Bowen disease to cutaneous squamous cell carcinoma: eight markers were verified from transcriptomic and proteomic analyses
Tang Biao, He Cai-feng, Lu Xiao-hong, Chang Xiao-li, Liu Wen-bei, Wang Jun, Ci Chao, Yuan Tao
Body mass index, genetic susceptibility, and Alzheimer's disease: a longitudinal study based on 475,813 participants from the UK Biobank
Shiqi Yuan, Wentao Wu, Wen Ma, Xiaxuan Huang, Tao Huang, MIn Peng, Anding Xu, Jun Lyu
Roles of neuroligins in central nervous system development: focus on glial neuroligins and neuron neuroligins
Xing Liu, Fuzhou Hua, Danying Yang, Yue Lin, Lieliang Zhang, Jun Ying, Hongguang Sheng, Xifeng Wang
Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
Espen Basmo Ellingsen, Gergana Bounova, Iliana Kerzeli, Irantzu Anzar, Donjete Simnica, Elin Aamdal, Tormod Guren, Trevor Clancy, Artur Mezheyeuski, Else Marit Inderberg, Sara M. Mangsbo, Mascha Binder, Eivind Hovig, Gustav Gaudernack
SGLT2 inhibitors improve kidney function and morphology by regulating renal metabolic reprogramming in mice with diabetic kidney disease
Yong-Ping Lu, Ze-Yu Zhang, Hong-Wei Wu, Li-Jing Fang, Bo Hu, Chun Tang, Yi-Qing Zhang, Lianghong Yin, Dong-E. Tang, Zhi-Hua Zheng, Ting Zhu, Yong Dai
Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications
Ruslan Rust, Rebecca Z. Weber, Melanie Generali, Debora Kehl, Chantal Bodenmann, Daniela Uhr, Debora Wanner, Kathrin J. Zürcher, Hirohide Saito, Simon P. Hoerstrup, Roger M. Nitsch, Christian Tackenberg
Can HPV Selfy be considered as a clinically validated HPV test for use in cervical cancer screening?
Marc Arbyn, Jesper Bonde, Kate Cushieri, Mario Poljak
Comparative profiling of single-cell transcriptome reveals heterogeneity of tumor microenvironment between solid and acinar lung adenocarcinoma
Dianke Li, Huansha Yu, Junjie Hu, Shaoling Li, Yilv Yan, Shuangyi Li, Liangdong Sun, Gening Jiang, Likun Hou, Lele Zhang, Peng Zhang
Detecting associated genes for complex traits shared across East Asian and European populations under the framework of composite null hypothesis testing
Jiahao Qiao, Zhonghe Shao, Yuxuan Wu, Ping Zeng, Ting Wang
Host-microbiome interactions regarding peri-implantitis and dental implant loss
Carlos Henrique Alves, Karolayne Larissa Russi, Natália Conceição Rocha, Fábio Bastos, Michelle Darrieux, Thais Manzano Parisotto, Raquel Girardello
MIR99AHG inhibits EMT in pulmonary fibrosis via the miR-136-5p/USP4/ACE2 axis
Jun Wang, Yuan Xiang, Sheng-Xi Yang, Hui-Min Zhang, Hui Li, Qi-Bei Zong, Le-Wei Li, Li-Li Zhao, Ruo-Han Xia, Chao Li, Le-Yuan Bao, Tong-Cun Zhang, Xing-Hua Liao
Revalidating the prognostic COVID-19 severity assessment (COSA) score for variants of concern
Verena Schöning, Evangelia Liakoni, Christine Baumgartner, Aristomenis K. Exadaktylos, Wolf E. Hautz, Andrew Atkinson, Felix Hammann
Soluble CCR2 gene therapy controls joint inflammation, cartilage damage, and the progression of osteoarthritis by targeting MCP-1 in a monosodium iodoacetate (MIA)-induced OA rat model
Hyun Sik Na, Seon-Yeong Lee, Dong Hwan Lee, Jin Seok Woo, Si-Young Choi, Keun-Hyung Cho, Seon Ae Kim, Eun Jeong Go, A Ram Lee, Jeong-Won Choi, Seok Jung Kim, Mi-La Cho
Long-term neuromuscular consequences of SARS-Cov-2 and their similarities with myalgic encephalomyelitis/chronic fatigue syndrome: results of the retrospective CoLGEM study
Frédérique Retornaz, Stanislas Rebaudet, Chloé Stavris, Yves Jammes
The potential impact of a probiotic: Akkermansia muciniphila in the regulation of blood pressure—the current facts and evidence
Arun Prasath Lakshmanan, Selvasankar Murugesan, Souhaila Al Khodor, Annalisa Terranegra
The renal pelvis urobiome in the unilateral kidney stone patients revealed by 2bRAD-M
Sen-Yuan Hong, Yuan-Yuan Yang, Jin-Zhou Xu, Qi-Dong Xia, Shao-Gang Wang, Yang Xun
Co-expression IL-15 receptor alpha with IL-15 reduces toxicity via limiting IL-15 systemic exposure during CAR-T immunotherapy
Ying Zhang, Qinghui Zhuang, Fang Wang, Can Zhang, Chang Xu, Aiqin Gu, William H. Zhong, Yi Hu, Xiaosong Zhong
LAG3 blockade coordinates with microwave ablation to promote CD8+ T cell-mediated anti-tumor immunity
Dong Shao, Yaping Chen, Hao Huang, Yingting Liu, Junjun Chen, Dawei Zhu, Xiao Zheng, Lujun Chen, Jingting Jiang
Inhibition of XPO1 with KPT-330 induces autophagy-dependent apoptosis in gallbladder cancer by activating the p53/mTOR pathway
Cheng Zhao, Zi-yi Yang, Jian Zhang, Ou Li, Shi-lei Liu, Chen Cai, Yi-jun Shu, Li-jia Pan, Wei Gong, Ping Dong
The prognostic value of the previous nephrectomy in pretreated metastatic renal cell carcinoma receiving immunotherapy: a sub-analysis of the Meet-URO 15 study
Sara Elena Rebuzzi, Alessio Signori, Giuseppe Luigi Banna, Annalice Gandini, Giuseppe Fornarini, Alessandra Damassi, Marco Maruzzo, Ugo De Giorgi, Umberto Basso, Silvia Chiellino, Luca Galli, Paolo Andrea Zucali, Emanuela Fantinel, Emanuele Naglieri, Giuseppe Procopio, Michele Milella, Francesco Boccardo, Lucia Fratino, Stefania Pipitone, Riccardo Ricotta, Stefano Panni, Veronica Mollica, Mariella Sorarù, Matteo Santoni, Alessio Cortellini, Veronica Prati, Hector Josè Soto Parra, Daniele Santini, Francesco Atzori, Marilena Di Napoli, Orazio Caffo, Marco Messina, Franco Morelli, Giuseppe Prati, Franco Nolè, Francesca Vignani, Alessia Cavo, Giandomenico Roviello, Pasquale Rescigno, Sebastiano Buti
A genetic map of the chromatin regulators to drug response in cancer cells
Bo Chen, Pengfei Li, Mingyue Liu, Kaidong Liu, Min Zou, Yiding Geng, Shuping Zhuang, Huanhuan Xu, Linzhu Wang, Tingting Chen, Yawei Li, Zhangxiang Zhao, Lishuang Qi, Yunyan Gu
Concomitant medication of cetirizine in advanced melanoma could enhance anti-PD-1 efficacy by promoting M1 macrophages polarization
Domenico Mallardo, Ester Simeone, Vito Vanella, Maria Grazia Vitale, Marco Palla, Luigi Scarpato, Miriam Paone, Teresa De Cristofaro, Valentina Borzillo, Alessio Cortellini, Francesca Sparano, Sandro Pignata, Francesco Fiore, Corrado Caracò, Piera Maiolino, Antonella Petrillo, Ernesta Cavalcanti, Secondo Lastoria, Paolo Muto, Alfredo Budillon, Sarah Warren, Paolo Antonio Ascierto
Assessing the causal association between human blood metabolites and the risk of epilepsy
Jiahao Cai, Xiaoyu Li, Shangbin Wu, Yang Tian, Yani Zhang, Zixin Wei, Zixiang Jin, Xiaojing Li, Xiong Chen, Wen-Xiong Chen
Efficacy and safety of novel oral anticoagulants in patients with atrial nonvalvular atrial fibrillation and diabetes mellitus: a systematic review and meta-analysis
Xuedong Jia, Zhao Yin, Wan Zhang, Shuzhang Du, Jian Kang
Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments
Jun Su, Yue Li, Qing Liu, Gang Peng, Chaoying Qin, Yang Li
Microbiota and metabolites alterations in proximal and distal gastric cancer patients
Yan Yang, Daofeng Dai, Wen Jin, Yingying Huang, Yingzi Zhang, Yiran Chen, Wankun Wang, Wu Lin, Xiangliu Chen, Jing Zhang, Haohao Wang, Haibin Zhang, Lisong Teng
Immune-related 3-lncRNA signature with prognostic connotation in a multi-cancer setting
Shimaa Sherif, Raghvendra Mall, Hossam Almeer, Adviti Naik, Abdulaziz Al Homaid, Remy Thomas, Jessica Roelands, Sathiya Narayanan, Mahmoud Gasim Mohamed, Shahinaz Bedri, Salha Bujassoum Al-Bader, Kulsoom Junejo, Davide Bedognetti, Wouter Hendrickx, Julie Decock
miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM)
Zongze He, Meixiong Cheng, Junting Hu, Lingtong Liu, Ping Liu, Longyi Chen, Deqian Cao, Jian Tang
CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis
Liwen Ren, Yihui Yang, Wan Li, Xiangjin Zheng, Jinyi Liu, Sha Li, Hong Yang, Yizhi Zhang, Binbin Ge, Sen Zhang, Weiqi Fu, Dexin Dong, Guanhua Du, Jinhua Wang
Comprehensive characterization of ubiquitinome of human colorectal cancer and identification of potential survival-related ubiquitination
Wei Zhang, Yan Yang, Liewen Lin, Jingquan He, Jingjing Dong, Bin Yan, Wanxia Cai, Yumei Chen, Lianghong Yin, Donge Tang, Fanna Liu, Yong Dai
Loss of endothelial EMCN drives tumor lung metastasis through the premetastatic niche
Guoxin Zhang, Mengyuan Li, Dandan Zhou, Xingjiu Yang, Wenlong Zhang, Ran Gao
Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy
Jingui Hu, Tao Liu, Fei Fu, Zekun Cui, Qiong Lai, Yuanyuan Zhang, Boyang Yu, Fuming Liu, Junping Kou, Fang Li
Circulating hypoxia-dependent miR-210 is increased in clinical sepsis subtypes: A cohort study
Rachel E Powell, Yi Yin Tai, Jason N Kennedy, Christopher W Seymour, Stephen Y Chan
CTRP1 prevents high fat diet-induced obesity and improves glucose homeostasis in obese and STZ-induced diabetic mice
Mingzhi Ren, Jianfei Pan, Xueying Yu, Kaile Chang, Xiaopeng Yuan, Chunbo Zhang
High expression of HNRNPR in ESCA combined with 18F-FDG PET/CT metabolic parameters are novel biomarkers for preoperative diagnosis of ESCA
Xiao-Yu Liu, Yan Gao, Xue-Yan Kui, Xu-Sheng Liu, Yao-hua Zhang, Yu Zhang, Chang-Bin Ke, Zhi-Jun Pei
Artificial intelligence for quantifying immune infiltrates interacting with stroma in colorectal cancer
Jing Yang, Huifen Ye, Xinjuan Fan, Yajun Li, Xiaomei Wu, Minning Zhao, Qingru Hu, Yunrui Ye, Lin Wu, Zhenhui Li, Xueli Zhang, Changhong Liang, Yingyi Wang, Yao Xu, Qian Li, Su Yao, Dingyun You, Ke Zhao, Zaiyi Liu
System analysis based on the cuproptosis-related genes identifies LIPT1 as a novel therapy target for liver hepatocellular carcinoma
Cheng Yan, Yandie Niu, Liukai Ma, Lifang Tian, Jiahao Ma
Multi-perspective comparison of the immune microenvironment of primary colorectal cancer and liver metastases
Yangsong He, Yanan Han, A-hui Fan, Danxiu Li, Boda Wang, Kun Ji, Xin Wang, Xiaodi Zhao, Yuanyuan Lu
System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma
Cheng Yan, Yandie Niu, Feng Li, Wei Zhao, Liukai Ma
LPAR5 confers radioresistance to cancer cells associated with EMT activation via the ERK/Snail pathway
Xiao-Ya Sun, Hao-Zheng Li, Da-Fei Xie, Shan-Shan Gao, Xin Huang, Hua Guan, Chen-Jun Bai, Ping-Kun Zhou
Inflammatory plasma proteins predict short-term mortality in patients with an acute myocardial infarction
T. Schmitz, E. Harmel, M. Heier, A. Peters, J. Linseisen, C. Meisinger
Record linkage based patient intersection cardinality for rare disease studies using Mainzelliste and secure multi-party computation
Tobias Kussel, Torben Brenner, Galina Tremper, Josef Schepers, Martin Lablans, Kay Hamacher
Pivotal interplays between fecal metabolome and gut microbiome reveal functional signatures in cerebral ischemic stroke
Lanlan Zhao, Cheng Wang, Shanxin Peng, Xiaosong Zhu, Ziyi Zhang, Yanyan Zhao, Jinling Zhang, Guoping Zhao, Tao Zhang, Xueyuan Heng, Lei Zhang
Recent developments in the probiotics as live biotherapeutic products (LBPs) as modulators of gut brain axis related neurological conditions
Duygu Ağagündüz, Feray Gençer Bingöl, Elif Çelik, Özge Cemali, Çiler Özenir, Fatih Özoğul, Raffaele Capasso
Alpha-ketoglutarate ameliorates abdominal aortic aneurysm via inhibiting PXDN/HOCL/ERK signaling pathways
Junjun Liu, Mingyuan Liu, Jiaxuan Feng, Hongqiao Zhu, Jianlie Wu, Heng Zhang, Shun Xiao, Zaiping Jing, Jian Zhou, Haitao Niu, Mingjin Guo
Decoding the colorectal cancer ecosystem emphasizes the cooperative role of cancer cells, TAMs and CAFsin tumor progression
Rongfang Shen, Ping Li, Botao Zhang, Lin Feng, Shujun Cheng
One-step fabrication of lidocaine/CalliSpheres® composites for painless transcatheter arterial embolization
Chuan Tian, Zijian Wang, Lei Huang, Yimin Liu, Kunpeng Wu, Zhaonan Li, Bin Han, Dechao Jiao, Xinwei Han, Yanan Zhao
CSPG4 expression in soft tissue sarcomas is associated with poor prognosis and low cytotoxic immune response
Laurys Boudin, A de Nonneville, Pascal Finetti, Léna Mescam, A Le Cesne, Antoine Italiano, Jean-Yves Blay, Daniel Birnbaum, Emilie Mamessier, François Bertucci
MicroRNA-223 negatively regulates the osteogenic differentiation of periodontal ligament derived cells by directly targeting growth factor receptors
Zheng Zhang, Minghui Wang, Youli Zheng, Yanmei Dai, Jiashu Chou, Xiaowei Bian, Pengcheng Wang, Changyi Li, Jing Shen
Single-cell transcriptomics reveals the role of Macrophage-Naïve CD4 + T cell interaction in the immunosuppressive microenvironment of primary liver carcinoma
Zhuomao Mo, Daiyuan Liu, Yihan Chen, Jin Luo, Wenjing Li, Jiahui Liu, Ling Yu, Bijun Huang, Shijun Zhang
Analysis of gene expression levels and their impact on survival in 31 cancer-types patients identifies novel prognostic markers and suggests unexplored immunotherapy treatment options in a wide range of malignancies
Claudia Giampietri, Francesca Scatozza, Elena Crecca, Virginia Vigiano Benedetti, Pier Giorgio Natali, Antonio Facchiano
TCF7/SNAI2/miR-4306 feedback loop promotes hypertrophy of ligamentum flavum
Yang Duan, Jianjun Li, Sujun Qiu, Songjia Ni, Yanlin Cao
A novel microRNA signature for the detection of melanoma by liquid biopsy
Claudia Sabato, Teresa Maria Rosaria Noviello, Alessia Covre, Sandra Coral, Francesca Pia Caruso, Zein Mersini Besharat, Elena Splendiani, Laura Masuelli, Cecilia Battistelli, Alessandra Vacca, Giuseppina Catanzaro, Agnese Po, Andrea Anichini, Michele Maio, Michele Ceccarelli, Anna Maria Di Giacomo, Elisabetta Ferretti
Trimethylamine, a gut bacteria metabolite and air pollutant, increases blood pressure and markers of kidney damage including proteinuria and KIM-1 in rats
Klaudia M. Maksymiuk, Mateusz Szudzik, Marta Gawryś-Kopczyńska, Maksymilian Onyszkiewicz, Emilia Samborowska, Izabella Mogilnicka, Marcin Ufnal
Radiomics features for assessing tumor-infiltrating lymphocytes correlate with molecular traits of triple-negative breast cancer
Guan-Hua Su, Yi Xiao, Lin Jiang, Ren-Cheng Zheng, He Wang, Yan Chen, Ya-Jia Gu, Chao You, Zhi-Ming Shao
Antigenic molecular mimicry in viral-mediated protection from cancer: the HIV case
Carmen Manolio, Concetta Ragone, Beatrice Cavalluzzo, Angela Mauriello, Maria Lina Tornesello, Franco M. Buonaguro, Angelo Salomone Megna, Giovanna D’Alessio, Roberta Penta, Maria Tagliamonte, Luigi Buonaguro
CASA: a comprehensive database resource for the COVID-19 Alternative Splicing Atlas
Yaxin Chen, Gang Wang, Jingyi Li, Lei Xia, Lin Zhu, Wenxing Li, Qiang Luo, Yinlu Liao, Yao Lin, Liyun Bi, Hubin Chen, Jiemei Chu, Yueqi Li, Jinming Su, Li Ye, Jun-jun Jiang, Hao Liang, Weimin Li, Sanqi An
An NADPH sensor that regulates cell ferroptosis
Guixing Kuang, Weidong Wang, Dan Xiong, Chong Zeng
Causality of genetically determined metabolites on anxiety disorders: a two-sample Mendelian randomization study
Gui Xiao, Qingnan He, Li Liu, Tingting Zhang, Mengjia Zhou, Xingxing Li, Yijun Chen, Yanyi Chen, Chunxiang Qin
Integrative analysis of m3C associated genes reveals METTL2A as a potential oncogene in breast Cancer
Shuai Wang, Huiting Li, Jiheng Liu, Qianqian Zhang, Wei Xu, Juanjuan Xiang, Li Fang, Ping Xu, Zheng Li
Prognosis-Related Nutritional Score for Cancer Patients (PRNS): a clinical nutritional score derived from a retrospective cohort study
Bingdong Zhang, Yuerui Li, Yongbing Chen
Domino hepatocyte transplantation using explanted human livers with metabolic defects attenuates D-GalN/LPS-induced acute liver failure
Guang-Peng Zhou, Shi-Peng Li, Yi-Zhou Jiang, Jie Sun, Yu-Le Tan, Zhi-Gui Zeng, Lin Wei, Wei Qu, Li-Ying Sun, Zhi-Jun Zhu
Combined association of triglyceride-glucose index and systolic blood pressure with all-cause and cardiovascular mortality among the general population
Yu Yu, Min Gu, Hao Huang, Sijing Cheng, Yu Deng, Chi Cai, Xuhua Chen, Hongxia Niu, Xiaohui Ning, Wei Hua
Novel pathogenic variants in CUBN uncouple proteinuria from renal function
Chun Gan, Xindi Zhou, Dan Chen, Huan Chi, Jiawen Qiu, Hui You, Yaxi Chen, Mo Wang, Haiping Yang, Wei Jiang, Qiu Li
Identification of DNA methylation-regulated differentially expressed genes in RA by integrated analysis of DNA methylation and RNA-Seq data
Runrun Zhang, Cen Chang, Yehua Jin, LingXia Xu, Ping Jiang, Kai Wei, Linshuai Xu, Shicheng Guo, Songtao Sun, Dongyi He
Mitochondrial transplantation: opportunities and challenges in the treatment of obesity, diabetes, and nonalcoholic fatty liver disease
Yifei Chen, Fuji Yang, Ying Chu, Zhihua Yun, Yongmin Yan, Jianhua Jin
Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin
Daniele Caracciolo, Giada Juli, Caterina Riillo, Adriana Coricello, Francesca Vasile, Sara Pollastri, Roberta Rocca, Francesca Scionti, Nicoletta Polerà, Katia Grillone, Mariamena Arbitrio, Nicoletta Staropoli, Basilio Caparello, Domenico Britti, Giovanni Loprete, Giosuè Costa, Maria Teresa Di Martino, Stefano Alcaro, Pierosandro Tagliaferri, Pierfrancesco Tassone
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis
Ruxia Deng, Xiansheng Lu, Chang Hong, Rui Cai, Ping Wang, Le Xiong, Xiaoyu Wang, Qiaoyu Chen, Jie Lin
Autoimmune gene expression profiling of fingerstick whole blood in Chronic Fatigue Syndrome
Zheng Wang, Michelle F. Waldman, Tara J. Basavanhally, Aviva R. Jacobs, Gonzalo Lopez, Regis Y. Perichon, Johnny J. Ma, Elyse M. Mackenzie, James B. Healy, Yixin Wang, Sarah A. Hersey
Genetic and epigenetic regulation of Catechol-O-methyltransferase in relation to inflammation in chronic fatigue syndrome and Fibromyalgia
Andrea Polli, Jolien Hendrix, Kelly Ickmans, Jelena Bakusic, Manosij Ghosh, Dora Monteyne, Brigitte Velkeniers, Bram Bekaert, Jo Nijs, Lode Godderis
Early remission in multiple sclerosis is linked to altered coherence of the Cerebellar Network
Marlene Tahedl, Seth M. Levine, Robert Weissert, Zacharias Kohl, De-Hyung Lee, Ralf A. Linker, Jens V. Schwarzbach
Transcriptome-based network analysis related to M2-like tumor-associated macrophage infiltration identified VARS1 as a potential target for improving melanoma immunotherapy efficacy
Zhengquan Wu, Ke Lei, Huaizhi Li, Jiali He, Enxian Shi
A narrative review of the moderating effects and repercussion of exercise intervention on osteoporosis: ingenious involvement of gut microbiota and its metabolites
Yuan-Wei Zhang, Mu-Min Cao, Ying-Juan Li, Xiang-Xu Chen, Qian Yu, Yun-Feng Rui
PRR34-AS1 promotes exosome secretion of VEGF and TGF-β via recruiting DDX3X to stabilize Rab27a mRNA in hepatocellular carcinoma
Zhilei Zhang, Ye Zhou, Yuming Jia, Chao Wang, Meng Zhang, Zhuo Xu
m6A-immune-related lncRNA prognostic signature for predicting immune landscape and prognosis of bladder cancer
Zi-Hao Feng, Yan-Ping Liang, Jun-Jie Cen, Hao-Hua Yao, Hai-Shan Lin, Jia-Ying Li, Hui Liang, Zhu Wang, Qiong Deng, Jia-Zheng Cao, Yong Huang, Jin-Huan Wei, Jun-Hang Luo, Wei Chen, Zhen-Hua Chen
Silencing eL31 suppresses the progression of colorectal cancer via targeting DEPDC1
Gaowa Sharen, Xiongfeng Li, Jiaxin Sun, Lei Zhang, Wen Xi, Xiaodong Zhao, Fei Han, Longlong Jia, Rong A, Haidong Cheng, Mingxing Hou
Scoring model based on the signature of non-m6A-related neoantigen-coding lncRNAs assists in immune microenvironment analysis and TCR-neoantigen pair selection in gliomas
Wenbo Zhao, Yibo Wu, Feihu Zhao, Zhiyi Xue, Wenyu Liu, Zenxin Cao, Zhimin Zhao, Bin Huang, Mingzhi Han, Xingang Li
Causal relationship between obesity, lifestyle factors and risk of benign prostatic hyperplasia: a univariable and multivariable Mendelian randomization study
Yong-Bo Wang, Lan Yang, Yu-Qing Deng, Si-Yu Yan, Li-Sha Luo, Ping Chen, Xian-Tao Zeng
Whole-cell tumor vaccines desialylated to uncover tumor antigenic Gal/GalNAc epitopes elicit anti-tumor immunity
Jianmei Huang, Meiying Li, Bingjie Mei, Junyang Li, Yi Zhu, Qiaoshan Guo, Jianming Huang, Guonan Zhang
The p-STAT3/ANXA2 axis promotes caspase-1-mediated hepatocyte pyroptosis in non-alcoholic steatohepatitis
Yun Feng, Wenhua Li, Zhuoya Wang, Ruling Zhang, Yan Li, Lijuan Zang, Peiwen Wang, Zhenghong Li, Yuwei Dong
The effects of probiotic administration on patients with prediabetes: a meta-analysis and systematic review
Ya Li, You Wu, Lili Wu, Lingling Qin, Tonghua Liu
Single-cell RNA sequencing identifies the properties of myelodysplastic syndrome stem cells
Yumei Liu, Haiyue Niu, Nan Song, Wei Zhang, Lijuan Li, Huaquan Wang, Rong Fu, Zonghong Shao
Apparent mineralocorticoid excess: comprehensive overview of molecular genetics
Yi-ting Lu, Di Zhang, Qiong-yu Zhang, Ze-ming Zhou, Kun-qi Yang, Xian-liang Zhou, Fan Peng
Evidence that the pituitary gland connects type 2 diabetes mellitus and schizophrenia based on large-scale trans-ethnic genetic analyses
Lei Cai, Yanlan Sun, Yonglin Liu, Wenzhong Chen, Lin He, Dong-Qing Wei
Assessing the genetic burden of familial hypercholesterolemia in a large middle eastern biobank
Geethanjali Devadoss Gandhi, Waleed Aamer, Navaneethakrishnan Krishnamoorthy, Najeeb Syed, Elbay Aliyev, Aljazi Al-Maraghi, Muhammad Kohailan, Jamil Alenbawi, Mohammed Elanbari, Borbala Mifsud, Younes Mokrab, Charbel Abi Khalil, Khalid A. Fakhro
Sepax-2 cell processing device: a study assessing reproducibility of concentrating thawed hematopoietic progenitor cells
Bechara Mfarrej, Olivier Vicari, Sarah Ouffai, Carine Malenfant, Angela Granata, Sophie Thevenet, Christian Chabannon, Claude Lemarié, Boris Calmels
Single-cell RNA sequencing reveals rebalancing of immunological response in patients with periodontitis after non-surgical periodontal therapy
Hansong Lee, Ji-Young Joo, Dong Hyun Sohn, Junho Kang, Yeuni Yu, Hae Ryoun Park, Yun Hak Kim
A photodynamically sensitized dendritic cell vaccine that promotes the anti-tumor effects of anti-PD-L1 monoclonal antibody in a murine model of head and neck squamous cell carcinoma
Shuang Li, Ding Wang, Jinzhang Cheng, Jicheng Sun, Dhan V. Kalvakolanu, Xue Zhao, Di Wang, Yunhan You, Ling Zhang, Dan Yu
Efficacy and safety of Treamid in the rehabilitation of patients after COVID-19 pneumonia: a phase 2, randomized, double-blind, placebo-controlled trial
Evgeny Bazdyrev, Maria Panova, Maria Brachs, Elena Smolyarchuk, Daria Tsygankova, Liudmila Gofman, Yana Abdyusheva, Fedor Novikov
Lymphatic metastasis-associated circRNA‒miRNA‒mRNA network for exploring the pathogenesis and therapeutic target of triple negative breast cancer based on whole-transcriptome sequencing analysis: an experimental verification study
Jiayue Luo, Dong Cao, Chuwen Hu, Zhen Liang, Yuanping Zhang, Jianguo Lai
Irradiation-induced exosomal HMGB1 to confer radioresistance via the PI3K/AKT/FOXO3A signaling pathway in ESCC
Xingyu Du, Xueyuan Zhang, Jing Dong, Naiyi Zou, Dong Guo, Weinan Yao, Xiaobin Wang, Shuguang Li, Chunyang Song, Ke Yan, Wenbin Shen, Shuchai Zhu
Chemotherapy induces ACE2 expression in breast cancer via the ROS-AKT-HIF-1α signaling pathway: a potential prognostic marker for breast cancer patients receiving chemotherapy
Xiaoyan Zuo, Sixin Ren, He Zhang, Jianfei Tian, Ruinan Tian, Baoai Han, Hui Liu, Qian Dong, Zhiyong Wang, Yanfen Cui, Ruifang Niu, Fei Zhang
Anthocyanin improves kidney function in diabetic kidney disease by regulating amino acid metabolism
Yi-Xi Li, Yong-Ping Lu, Donge Tang, Bo Hu, Ze-Yu Zhang, Hong-Wei Wu, Li-Jing Fan, Kai-Wen Cai, Chun Tang, Yi-Qing Zhang, Ling Hong, Jing-jing Dong, Bao-zhang Guan, Liang-Hong Yin, Yong Dai, Wei-bin Bai, Zhi-Hua Zheng, Ting Zhu
SOX21-AS1 activated by STAT6 promotes pancreatic cancer progression via up-regulation of SOX21
Dandan Yu, Zhigang Zhao, Li Wang, Shishi Qiao, Zhen Yang, Qiang Wen, Guanghui Zhu
Ophthalmic artery changes in type 2 diabetes with and without acute coronary syndrome
Lan-ting Wu, Jia-lin Wang, Yan-ling Wang
Magnetique: an interactive web application to explore transcriptome signatures of heart failure
Thiago Britto-Borges, Annekathrin Ludt, Etienne Boileau, Enio Gjerga, Federico Marini, Christoph Dieterich
Genome-wide profiling of retroviral DNA integration and its effect on clinical pre-infusion CAR T-cell products
Lipei Shao, Rongye Shi, Yingdong Zhao, Hui Liu, Alexander Lu, Jinxia Ma, Yihua Cai, Tatyana Fuksenko, Alejandra Pelayo, Nirali N. Shah, James N. Kochenderfer, Scott M. Norberg, Christian Hinrichs, Steven L. Highfill, Robert P Somerville, Sandhya R. Panch, Ping Jin, David F. Stroncek
HiTIMED: hierarchical tumor immune microenvironment epigenetic deconvolution for accurate cell type resolution in the tumor microenvironment using tumor-type-specific DNA methylation data
Ze Zhang, John K. Wiencke, Karl T. Kelsey, Devin C. Koestler, Brock C. Christensen, Lucas A. Salas
Simultaneous measurement of the size and methylation of chromosome 4qA-D4Z4 repeats in facioscapulohumeral muscular dystrophy by long-read sequencing
Yosuke Hiramuki, Yuriko Kure, Yoshihiko Saito, Megumu Ogawa, Keiko Ishikawa, Madoka Mori-Yoshimura, Yasushi Oya, Yuji Takahashi, Dae-Seong Kim, Noriko Arai, Chiaki Mori, Tsuyoshi Matsumura, Tadanori Hamano, Kenichiro Nakamura, Koji Ikezoe, Shinichiro Hayashi, Yuichi Goto, Satoru Noguchi, Ichizo Nishino
Patterns of change in obesity indices and other cardiometabolic risk factors before the diagnosis of type 2 diabetes: two decades follow-up of the Tehran lipid and glucose study
Fatemeh Koohi, Nooshin Ahmadi, Fereidoun Azizi, Davood Khalili, Majid Valizadeh
Modification of mesenchymal stem cells for cartilage-targeted therapy
Jianghong Huang, Qisong Liu, Jiang Xia, Xi Chen, Jianyi Xiong, Lei Yang, Yujie Liang
Collection of peripheral blood mononucleated cells for chronic graft-versus-host disease immunology research: safety and effectiveness of leukapheresis in 132 patients
Alain Mina, Lauren Curtis, Kamille West, Yu Ying Yau, Edward W. Cowen, Frances Hakim, Steven Z. Pavletic
CAFs-derived SCUBE1 promotes malignancy and stemness through the Shh/Gli1 pathway in hepatocellular carcinoma
Jungang Zhao, Rizhao Li, Jiacheng Li, Ziyan Chen, Zixia Lin, Baofu Zhang, Liming Deng, Gang Chen, Yi Wang
Promotion of a synthetic degradation of activated STAT6 by PARP-1 inhibition: roles of poly(ADP-ribosyl)ation, calpains and autophagy
Jeffrey Wang, Mohamed A. Ghonim, Salome V. Ibba, Hanh H. Luu, Yucel Aydin, Peter A. Greer, A. Hamid Boulares
Ca2+ dysregulation in cardiac stromal cells sustains fibro-adipose remodeling in Arrhythmogenic Cardiomyopathy and can be modulated by flecainide
Angela S. Maione, Pawan Faris, Lara Iengo, Valentina Catto, Luca Bisonni, Francesco Lodola, Sharon Negri, Michela Casella, Anna Guarino, Gianluca Polvani, Marina Cerrone, Claudio Tondo, Giulio Pompilio, Elena Sommariva, Francesco Moccia
Targeted delivery of ZNF416 siRNA-loaded liposomes attenuates experimental pulmonary fibrosis
Demin Cheng, Ziwei Li, Yue Wang, Haojie Xiong, Wenqing Sun, Siyun Zhou, Yi Liu, Chunhui Ni
Automatic segmentation of the gross target volume in radiotherapy for lung cancer using transresSEUnet 2.5D Network
Hui Xie, Zijie Chen, Jincheng Deng, Jianfang Zhang, Hanping Duan, Qing Li
Celastrol elicits antitumor effects by inhibiting the STAT3 pathway through ROS accumulation in non-small cell lung cancer
Zhucheng Zhao, Yanmao Wang, Yuyan Gong, Xian Wang, Luyao Zhang, Haiyang Zhao, Jifa Li, Jiandong Zhu, Xiaoying Huang, Chengguang Zhao, Lehe Yang, Liangxing Wang
DNA methylation predicts the outcome of COVID-19 patients with acute respiratory distress syndrome
Martina Bradic, Sarah Taleb, Binitha Thomas, Omar Chidiac, Amal Robay, Nessiya Hassan, Joel Malek, Ali Ait Hssain, Charbel Abi Khalil
Differential regulation of TNFα and IL-6 expression contributes to immune evasion in prostate cancer
Ida Deichaite, Timothy J. Sears, Leisa Sutton, Daniel Rebibo, Kylie Morgan, Tyler Nelson, Brent Rose, Pablo Tamayo, Napoleone Ferrara, Fotis Asimakopoulos, Hannah Carter
MICAL1 facilitates pancreatic cancer proliferation, migration, and invasion by activating WNT/β-catenin pathway
Kun Cai, Lu Deng, Dijie Zheng, Lin Li, Zhiwei He, Chao Yu
Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease
Zhiyong He, Yangyang Bin, Guangshun Chen, Qiang Li, Wenling Fan, Yongqiang Ma, Junfang Yi, Xiaohua Luo, Zhi Tan, Jiequn Li
A novel small molecule glycolysis inhibitor WZ35 exerts anti-cancer effect via metabolic reprogramming
Lihua Wang, Zheng Zhu, Qi Liang, Yecheng Tao, Gaowei Jin, Yaoyao Zhong, Jichen Dai, Ruixia Dai, Zhixiang Wang, Junbo Chen, Lingjie Zhou, Shouyu Ke, Bin Zheng, Linhua Lan, Xiaokun Lin, Tongke Chen
Integration of CRISPR/Cas9 with artificial intelligence for improved cancer therapeutics
Ajaz A. Bhat, Sabah Nisar, Soumi Mukherjee, Nirmalya Saha, Nageswari Yarravarapu, Saife N. Lone, Tariq Masoodi, Ravi Chauhan, Selma Maacha, Puneet Bagga, Punita Dhawan, Ammira Al-Shabeeb Akil, Wael El-Rifai, Shahab Uddin, Ravinder Reddy, Mayank Singh, Muzafar A. Macha, Mohammad Haris
Circular RNAs in organ injury: recent development
Ryan Wong, Yiwen Zhang, Hailin Zhao, Daqing Ma
Integrating Single-cell RNA-seq to construct a Neutrophil prognostic model for predicting immune responses in non-small cell lung cancer
Jianyu Pang, Qian Yu, Yongzhi Chen, Hongjun Yuan, Miaomiao Sheng, Wenru Tang
Current strategies employed in the manipulation of gene expression for clinical purposes
Hsing-Chuan Tsai, Violena Pietrobon, Maoyu Peng, Suning Wang, Lihong Zhao, Francesco M. Marincola, Qi Cai
A circular network of purine metabolism as coregulators of dilated cardiomyopathy
Ge Wang, Rongjun Zou, Libao Liu, Zongtao Wang, Zengxiao Zou, Songtao Tan, Wenliu Xu, Xiaoping Fan
Integrative analyses of maternal plasma cell-free DNA nucleosome footprint differences reveal chromosomal aneuploidy fetuses gene expression profile
Min Zhang, Kun Li, Shoufang Qu, Zhiwei Guo, Yuanli Wang, Xu Yang, Junhua Zhou, Guojun Ouyang, Rongtao Weng, Fenxia Li, Yingsong Wu, Xuexi Yang
HNRNPA2B1-mediated m6A modification of TLR4 mRNA promotes progression of multiple myeloma
Chuiming Jia, Yiwei Guo, Yao Chen, Xinya Wang, Qiuting Xu, Yu Zhang, Lina Quan
Clinical improvement of sepsis by extracorporeal centrifugal leukocyte apheresis in a porcine model
Lei Zhou, Dong Zhang, Ling Kong, Xiaodong Xu, Dehua Gong
Biological role of matrix stiffness in tumor growth and treatment
Boer Deng, Ziyi Zhao, Weimin Kong, Chao Han, Xiaochang Shen, Chunxiao Zhou
Characterization of the effect of histone deacetylation inhibitors on CD8+ T cells in the context of aging
Georgiana Toma, Eliza Karapetian, Chiara Massa, Dagmar Quandt, Barbara Seliger
Triple blockade of Ido-1, PD-L1 and MEK as a potential therapeutic strategy in NSCLC
Carminia Maria Della Corte, Vincenza Ciaramella, Kavya Ramkumar, Giovanni Vicidomini, Alfonso Fiorelli, Valerio Nardone, Salvatore Cappabianca, Immacolata Cozzolino, Federica Zito Marino, Gaetano Di Guida, Qi Wang, Robert Cardnell, Carl Michael Gay, Davide Ciardiello, Erika Martinelli, Teresa Troiani, Giulia Martini, Stefania Napolitano, Jing Wang, Lauren Averett Byers, Fortunato Ciardiello, Floriana Morgillo
Innate immunity, cytokine storm, and inflammatory cell death in COVID-19
Rajendra Karki, Thirumala-Devi Kanneganti
Temporal regulation of notch activation improves arteriovenous fistula maturation
Qunying Guo, Guang Chen, Hunter Cheng, Ying Qing, Luan Truong, Quan Ma, Yun Wang, Jizhong Cheng
Targeting HSP47 and HSP70: promising therapeutic approaches in liver fibrosis management
Eslam E. Abd El-Fattah, Amr Y. Zakaria
Comparison of clinical outcomes of frozen-thawed D5 and D6 blastocysts undergoing preimplantation genetic testing
Guanling Yu, Shuiying Ma, Hui Liu, Yujin Liu, Haozhen Zhang, Wenjia Zhang, Keliang Wu
Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy
John Sieh Dumbuya, Siqi Li, Lili Liang, Yanchen Chen, Jiang Du, Qiyi Zeng
Circular RNA circLOC101928570 suppresses systemic lupus erythematosus progression by targeting the miR-150-5p/c-myb axis
Xingwang Zhao, Rui Dong, Zhongwei Tang, Juan Wang, Chunyou Wang, Zhiqiang Song, Bing Ni, Longlong Zhang, Xiaochong He, Yi You
Unilateral acute lung injury in pig: a promising animal model
Johannes Geilen, Matthias Kainz, Bernhard Zapletal, Silvana Geleff, Wilfried Wisser, Barbara Bohle, Thomas Schweiger, Marcus J. Schultz, Edda Tschernko
Paxlovid accelerates cartilage degeneration and senescence through activating endoplasmic reticulum stress and interfering redox homeostasis
Keyu Kong, Yongyun Chang, Hua Qiao, Chen Zhao, Xuzhuo Chen, Kewei Rong, Pu Zhang, Minghao Jin, Jingwei Zhang, Huiwu Li, Zanjing Zhai
Evaluating the frequency and the impact of pharmacogenetic alleles in an ancestrally diverse Biobank population
Shefali S. Verma, Karl Keat, Binglan Li, Glenda Hoffecker, Marjorie Risman, Katrin Sangkuhl, Michelle Whirl-Carrillo, Scott Dudek, Anurag Verma, Teri E. Klein, Marylyn D. Ritchie, Sony Tuteja
Chagasic cardiomyopathy is marked by a unique signature of activated CD4+ T cells
Gregório Guilherme Almeida, Inga Rimkute, Isabela Natália Pascoal Campos do Vale, Thomas Liechti, Priscilla Miranda Henriques, Ester Roffe, Fernanda Fortes de Araújo, Manoel Otávio da Costa Rocha, Silvana Maria Elói Santos, Olindo Assis Martins-Filho, Dragana Jankovic, Alan Sher, Andrea Teixeira-Carvalho, Mario Roederer, Lis Ribeiro do Valle Antonelli
A weighted non-negative matrix factorization approach to predict potential associations between drug and disease
Mei-Neng Wang, Xue-Jun Xie, Zhu-Hong You, De-Wu Ding, Leon Wong
Clinical application of noninvasive chromosomal screening for elective single-blastocyst transfer in frozen-thawed cycles
Rui Chen, Ni Tang, Hongzi Du, Yaxin Yao, Yangyun Zou, Jing Wang, Dunmei Zhao, Xueliang Zhou, Yang Luo, Lei Li, Yuling Mao
High VSX1 expression promotes the aggressiveness of clear cell renal cell carcinoma by transcriptionally regulating FKBP10
Wenliang Ma, Xin Li, Lei Yang, Jun Pan, Yi Chen, Yanwen Lu, Xiang Dong, Dongmei Li, Weidong Gan
Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma
Jiayun Wei, Jia Yao, Chendong Yang, Yongcui Mao, Dan Zhu, Ye Xie, Pinyan Liu, Mengchao Yan, Longfei Ren, Yan Lin, Qiuxia Zheng, Xun Li
Platinum-resistance in epithelial ovarian cancer: an interplay of epithelial–mesenchymal transition interlinked with reprogrammed metabolism
Dilys Leung, Zoe K. Price, Noor A. Lokman, Wanqi Wang, Lizamarie Goonetilleke, Elif Kadife, Martin K. Oehler, Carmela Ricciardelli, George Kannourakis, Nuzhat Ahmed
Noninvasive prediction of axillary lymph node status in breast cancer using promoter profiling of circulating cell-free DNA
Zhi-Wei Guo, Qing Liu, Xu Yang, Geng-Xi Cai, Bo-Wei Han, Li-Min Huang, Chun-Xi Li, Zhi-Kun Liang, Xiang-Ming Zhai, Li Lin, Kun Li, Min Zhang, Tian-Cai Liu, Rui-lin Pan, Ying-Song Wu, Xue-Xi Yang
The intrarenal landscape of T cell receptor repertoire in clear cell renal cell cancer
Wei Zhang, Qian Zhang, Chao Zhu, Zhiyuan Shi, Chen Shao, Yujie Chen, Nan Wang, Yanxia Jiang, Qing Liang, Kejia Wang
Monocytes educated by cancer-associated fibroblasts secrete exosomal miR-181a to activate AKT signaling in breast cancer cells
Katayoon Pakravan, Majid Mossahebi-Mohammadi, Mohammad H. Ghazimoradi, William C. Cho, Majid Sadeghizadeh, Sadegh Babashah
Survival outcomes following treatment delays among patients with early-stage female cancers: a nationwide study
Yu Min, Zheran Liu, Rendong Huang, Ruidan Li, Jing Jin, Zhigong Wei, Ling He, Yiyan Pei, Ning Li, Yongllin Su, Xiaolin Hu, Xingchen Peng
Estrogen antagonizes ASIC1a-induced chondrocyte mitochondrial stress in rheumatoid arthritis
Zhuoyan Zai, Yayun Xu, Xuewen Qian, Zihan Li, Ziyao Ou, Tao Zhang, Longfei Wang, Yian Ling, Xiaoqing Peng, Yihao Zhang, Feihu Chen
Current advances in gene therapy of mitochondrial diseases
Vladislav O. Soldatov, Marina V. Kubekina, Marina Yu. Skorkina, Andrei E. Belykh, Tatiana V. Egorova, Mikhail V. Korokin, Mikhail V. Pokrovskiy, Alexey V. Deykin, Plamena R. Angelova
Reconstruction of the gastric cancer microenvironment after neoadjuvant chemotherapy by longitudinal single-cell sequencing
Yingtai Chen, Jianhua Yin, Lulu Zhao, Guangyu Zhou, Shichen Dong, Yueming Zhang, Penghui Niu, Hu Ren, Tianjiao Zheng, Juan Yan, Wenbin Li, Peiqin Ma, Cuijuan Zhang, Chen Wei, George Church, Guibo Li, Dongbing Zhao
Polygenic risk of paclitaxel-induced peripheral neuropathy: a genome-wide association study
Kosar Hooshmand, David Goldstein, Hannah C. Timmins, Tiffany Li, Michelle Harrison, Michael L. Friedlander, Craig R. Lewis, Justin G. Lees, Gila Moalem-Taylor, Boris Guennewig, Susanna B. Park, John B. Kwok
Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis
Tao Liu, Jing Gu, Yi Yuan, Qunfang Yang, Peng-Fei Zheng, Changyu Shan, Fangqin Wang, Hongwei Li, Xiang-Qun Xie, Xiao-Hong Chen, Qin Ouyang
Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art review
Yue Li, Yuliang Jiang, Bin Qiu, Haitao Sun, Junjie Wang
Dyslipidemia induced large-scale network connectivity abnormality facilitates cognitive decline in the Alzheimer’s disease
Qing Wang, Feifei Zang, Cancan He, Zhijun Zhang, Chunming Xie
Smooth muscle cell fate decisions decipher a high-resolution heterogeneity within atherosclerosis molecular subtypes
Ge Zhang, Zaoqu Liu, Jinhai Deng, Long Liu, Yu Li, Siyuan Weng, Chunguang Guo, Zhaokai Zhou, Li Zhang, Xiaofang Wang, Gangqiong Liu, Jiacheng Guo, Jing Bai, Yunzhe Wang, Youyou Du, Tao-Sheng Li, Junnan Tang, Jinying Zhang
Brain fog of post-COVID-19 condition and Chronic Fatigue Syndrome, same medical disorder?
N. Azcue, J. C. Gómez-Esteban, M. Acera, B. Tijero, T. Fernandez, N. Ayo-Mentxakatorre, T. Pérez-Concha, A. Murueta-Goyena, J. V. Lafuente, Á. Prada, A. López de Munain, G. Ruiz-Irastorza, L. Ribacoba, I. Gabilondo, R. Del Pino
Continuous high-frequency deep brain stimulation of the anterior insula modulates autism-like behavior in a valproic acid-induced rat model
Lifei Xiao, Shucai Jiang, Yangyang Wang, Caibin Gao, Cuicui Liu, Xianhao Huo, Wenchao Li, Baorui Guo, Chaofan Wang, Yu Sun, Anni Wang, Yan Feng, Feng Wang, Tao Sun
GCN5L1-mediated TFAM acetylation at K76 participates in mitochondrial biogenesis in acute kidney injury
Tingting Lv, Yu Zhang, XingZhao Ji, Shengnan Sun, Li Xu, Weixia Ma, Yi Liu, Qiang Wan
Potential therapeutic strategies for photoreceptor degeneration: the path to restore vision
Fereshteh Karamali, Sanaz Behtaj, Shahnaz Babaei-Abraki, Hanieh Hadady, Atefeh Atefi, Soraya Savoj, Sareh Soroushzadeh, Samaneh Najafian, Mohammad Hossein Nasr Esfahani, Henry Klassen
Genetically predicted testosterone and cancers risk in men: a two-sample Mendelian randomization study
Junke Chang, Yongming Wu, Sicheng Zhou, Ye Tian, Yan Wang, Jie Tian, Wenpeng Song, Yinxian Dong, Jue Li, Ziyi Zhao, Guowei Che
CT-based radiogenomic analysis dissects intratumor heterogeneity and predicts prognosis of colorectal cancer: a multi-institutional retrospective study
Min-Er Zhong, Xin Duan, Ma-yi-di-li Ni-jia-ti, Haoning Qi, Dongwei Xu, Du Cai, Chenghang Li, Zeping Huang, Qiqi Zhu, Feng Gao, Xiaojian Wu
Development of a risk prediction model for bloodstream infection in patients with fever of unknown origin
Teng Xu, Shi Wu, Jingwen Li, Li Wang, Haihui Huang
Single-cell profiles reveal tumor cell heterogeneity and immunosuppressive microenvironment in Waldenström macroglobulinemia
Hao Sun, Teng Fang, Tingyu Wang, Zhen Yu, Lixin Gong, Xiaojing Wei, Huijun Wang, Yi He, Lanting Liu, Yuting Yan, Weiwei Sui, Yan Xu, Shuhua Yi, Lugui Qiu, Mu Hao
A comparison of health-related factors between patients diagnosed with ME/CFS and patients with a related symptom picture but no ME/CFS diagnosis: a cross-sectional exploratory study
Gabriella Bernhoff, Eva Rasmussen-Barr, Lina Bunketorp Käll
A bispecific, crosslinking lectibody activates cytotoxic T cells and induces cancer cell death
Francesca Rosato, Rajeev Pasupuleti, Jana Tomisch, Ana Valeria Meléndez, Dajana Kolanovic, Olga N. Makshakova, Birgit Wiltschi, Winfried Römer
A novel murine model of combined hepatocellular carcinoma and intrahepatic cholangiocarcinoma
Ru-Chen Xu, Fu Wang, Jia-Lei Sun, Weinire Abuduwaili, Guang-Cong Zhang, Zhi-Yong Liu, Tao-Tao Liu, Ling Dong, Xi-Zhong Shen, Ji-Min Zhu
Muscle sodium content in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Elisabeth Petter, Carmen Scheibenbogen, Peter Linz, Christian Stehning, Klaus Wirth, Titus Kuehne, Marcus Kelm
Acidic ascites inhibits ovarian cancer cell proliferation and correlates with the metabolomic, lipidomic and inflammatory phenotype of human patients
Qianlu Yang, Gyuntae Bae, Giorgi Nadiradze, Arianna Castagna, Georgy Berezhnoy, Laimdota Zizmare, Aditi Kulkarni, Yogesh Singh, Frank J. Weinreich, Stefan Kommoss, Marc A. Reymond, Christoph Trautwein
Incidence and severity of immune-related hepatitis after dual checkpoint therapy is linked to younger age independent of herpes virus immunity
Zhen Zhang, David Rafei-Shamsabadi, Saskia Lehr, Nico Buettner, Rebecca Diehl, Daniela Huzly, David J Pinato, Robert Thimme, Frank Meiss, Bertram Bengsch
Disruption of C/EBPβ-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain
Dan Wu, Yanqiong Zhang, Chunhui Zhao, Qiuyue Li, Junhong Zhang, Jiaxin Han, Zhijian Xu, Junfang Li, Yan Ma, Ping Wang, Haiyu Xu
The role of the oral microbiome in smoking-related cardiovascular risk: a review of the literature exploring mechanisms and pathways
Katherine A. Maki, Sukirth M. Ganesan, Brianna Meeks, Nicole Farmer, Narjis Kazmi, Jennifer J. Barb, Paule V. Joseph, Gwenyth R. Wallen
Analysis of correlations between gut microbiota, stool short chain fatty acids, calprotectin and cardiometabolic risk factors in postmenopausal women with obesity: a cross-sectional study
Igor Łoniewski, Monika Szulińska, Mariusz Kaczmarczyk, Konrad Podsiadło, Daniel Styburski, Karolina Skonieczna-Żydecka, Paweł Bogdański
Targeting macrophages: a novel treatment strategy in solid tumors
Mengmeng Liu, Lina Liu, Yongping Song, Wei Li, Linping Xu
Longitudinal transcriptional analysis of peripheral blood leukocytes in COVID-19 convalescent donors
Mallikarjuna R. Gedda, Patrick Danaher, Lipei Shao, Martin Ongkeko, Leonard Chen, Anh Dinh, Mame Thioye Sall, Opal L. Reddy, Christina Bailey, Amy Wahba, Inna Dzekunova, Robert Somerville, Valeria De Giorgi, Ping Jin, Kamille West, Sandhya R. Panch, David F. Stroncek
Calcitriol increases MBNL1 expression and alleviates myotonic dystrophy phenotypes in HSALR mouse models
Kun Huang, Dan-Dan Wang, Wen-Bao Hu, Wei-Qian Zeng, Xia Xu, Qiu-Xiang Li, Fang-Fang Bi, Huan Yang, Jian Qiu
Genome-wide association study reveals ethnicity-specific SNPs associated with ankylosing spondylitis in the Taiwanese population
Ching-Lung Ko, Wei-Zhi Lin, Meng-Ting Lee, Yu-Tien Chang, Hung-Che Lin, Yi-Syuan Wu, Jun-Fu Lin, Ke-Ting Pan, Yu-Chuan Chang, Ko-Han Lee, Yi-Lun Lee, Tsung-Ting Hsieh, Jia-Hsin Huang, Chih-Hung Wang, Sung-Sen Yang, Hsiang-Cheng Chen, Chi-Ming Chu
Kinin B1 receptor blockade attenuates hepatic fibrosis and portal hypertension in chronic liver diseases in mice
Dileep Reddy Rampa, Huiying Feng, Sivakumar Allur-Subramaniyan, Kwanseob Shim, Anton Pekcec, Dongwon Lee, Henri Doods, Dongmei Wu
Effects of Malate Ringer's solution on myocardial injury in sepsis and enforcement effects of TPP@PAMAM-MR
Lei Tan, Han She, Jie Zheng, Xiaoyong Peng, Ningke Guo, Bindan Zhang, Yue Sun, Chunhua Ma, Shenglian Xu, Daiqin Bao, Yuanqun Zhou, Qinghui Li, Qingxiang Mao, Liangming Liu, Yi Hu, Tao Li
An extensive bioinformatics study on the role of mitochondrial solute carrier family 25 in PC and its mechanism behind affecting immune infiltration and tumor energy metabolism
Qiang Zhang, Yubao Tang, Shuai Sun, Qiuyi Xie, Jie Yao, Xiaodong Wang, Jianjun Qian, Zhennan Li
Analysis of new treatments proposed for malignant pleural mesothelioma raises concerns about the conduction of clinical trials in oncology
Tomer Meirson, Valerio Nardone, Francesca Pentimalli, Gal Markel, David Bomze, Maria D’Apolito, Pierpaolo Correale, Antonio Giordano, Luigi Pirtoli, Camillo Porta, Steven G Gray, Luciano Mutti
Correction: Demethylation at enhancer upregulates MCM2 and NUP37 expression predicting poor survival in hepatocellular carcinoma patients
Zengwei Tang, Yuan Yang, Wen Chen, Enliang Li, Tingbo Liang
Multi-scale pathology image texture signature is a prognostic factor for resectable lung adenocarcinoma: a multi-center, retrospective study
Yumeng Wang, Xipeng Pan, Huan Lin, Chu Han, Yajun An, Bingjiang Qiu, Zhengyun Feng, Xiaomei Huang, Zeyan Xu, Zhenwei Shi, Xin Chen, Bingbing Li, Lixu Yan, Cheng Lu, Zhenhui Li, Yanfen Cui, Zaiyi Liu, Zhenbing Liu
Long-term survivors demonstrate superior quality of life after haploidentical stem cell transplantation to matched sibling donor transplantation
Xiaoyu Zhang, Jiao Wang, Yuqiu Liu, Jie Liu, Bei Wang, Qiuhui Zhang, Wei Guan, Huijuan Zhang, Li Xu, Guiying Liu, Ping Zhang, Yi He, Sizhou Feng, Mingzhe Han, Changping Li, Erlie Jiang, Wenjun Xie
Monophosphoryl lipid A ameliorates radiation-induced lung injury by promoting the polarization of macrophages to the M1 phenotype
Xingdong Guo, Lehui Du, Na Ma, Pei Zhang, Yuan Wang, Yanan Han, Xiang Huang, Qian Zhang, Xin Tan, Xiao Lei, Baolin Qu
Genetic risk factors for ME/CFS identified using combinatorial analysis
Sayoni Das, Krystyna Taylor, James Kozubek, Jason Sardell, Steve Gardner
The prebiotic effects of soluble dietary fiber mixture on renal anemia and the gut microbiota in end-stage renal disease patients on maintenance hemodialysis: a prospective, randomized, placebo-controlled study
Yang Li, Min Han, Jia Song, Shijin Liu, Yongjun Wang, Xinhuan Su, Kai Wei, Zhen Xu, Hui Li, Zunsong Wang
Naturally selected CD7 CAR-T therapy without genetic editing demonstrates significant antitumour efficacy against relapsed and refractory acute myeloid leukaemia (R/R-AML)
Yu Lu, Ying Liu, Shupeng Wen, Na Kuang, Xuejun Zhang, Jianqiang Li, Fuxu Wang
Sleep patterns correlates with the efficacy of tDCS on post-stroke patients with prolonged disorders of consciousness
Jie Yu, Yuehao Wu, Biwen Wu, Chuan Xu, Jiaye Cai, Xinrui Wen, Fanxia Meng, Li Zhang, Fangping He, Lirong Hong, Jian Gao, Jingqi Li, Jintai Yu, Benyan Luo
Identification of ZBTB9 as a potential therapeutic target against dysregulation of tumor cells proliferation and a novel biomarker in Liver Hepatocellular Carcinoma
Zhenshan Zhang, Leilei Wu, Juan Li, Jiayan Chen, Qi Yu, Hui Yao, Yaping Xu, Liang Liu
SPTBN1 abrogates renal clear cell carcinoma progression via glycolysis reprogramming in a GPT2-dependent manner
Jiajin Wu, Chenkui Miao, Yuhao Wang, Songbo Wang, Zhongyuan Wang, Yiyang Liu, Xiaoyi Wang, Zengjun Wang
Uncovering the gene regulatory network of type 2 diabetes through multi-omic data integration
Jiachen Liu, Shenghua Liu, Zhaomei Yu, Xiaorui Qiu, Rundong Jiang, Weizheng Li
Stage-specific requirement for METTL3-dependent m6A modification during dental pulp stem cell differentiation
Haiyun Luo, Wenjing Liu, Yachuan Zhou, Yanli Zhang, Junrong Wu, Ruolan Wang, Longquan Shao
Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors
Kwong-Kwok Wong, Nicholas W. Bateman, Chun Wai Ng, Yvonne T. M. Tsang, Charlotte S. Sun, Joseph Celestino, Tri V. Nguyen, Anais Malpica, R. Tyler Hillman, Jianhua Zhang, P. Andrew Futreal, Christine Rojas, Kelly A. Conrads, Brian L. Hood, Clifton L. Dalgard, Matthew D. Wilkerson, Neil T. Phippen, Thomas P. Conrads, George L. Maxwell, Anil K. Sood, David M. Gershenson
Urinary exosomal hsa_circ_0001250 as a novel diagnostic biomarker of idiopathic membranous nephropathy
Qianyu Li, Mingzhu Xu, Zhiping Zhang, Min Yin, Yucheng Zhang, Feng Liu
A simple and effective method to purify and activate T cells for successful generation of chimeric antigen receptor T (CAR-T) cells from patients with high monocyte count
Haiying Wang, Shih-Ting Tsao, Mingyuan Gu, Chengbing Fu, Feng He, Xiu Li, Mian Zhang, Na Li, Hong-Ming Hu
Genome-wide associated variants of subclinical atherosclerosis among young people with HIV and gene-environment interactions
Jiayu He, Haijiang Lin, Yingying Ding, Xing Liu, Kelin Xu, Xiaoxiao Chen, Weiwei Shen, Sujuan Zhou, Miaochen Wang, Jingjing Xia, Na He
Retraction Note: Serum sphingosine-1-phosphate levels and Sphingosine-1-Phosphate gene polymorphisms in acute respiratory distress syndrome: a multicenter prospective study
Jiangnan Zhao, Yan Tan, Li Wang, Xin Su, Yi Shi
A combination of molecular and clinical parameters provides a new strategy for high-grade serous ovarian cancer patient management
Melissa Bradbury, Eva Borràs, Marta Vilar, Josep Castellví, José Luis Sánchez-Iglesias, Assumpció Pérez-Benavente, Antonio Gil-Moreno, Anna Santamaria, Eduard Sabidó
Downregulation of SMIM3 inhibits growth of leukemia via PI3K-AKT signaling pathway and correlates with prognosis of adult acute myeloid leukemia with normal karyotype
Yu Liu, Yufei Chen, Yajun Liu, Mengya Li, Yu Zhang, Luyao Shi, Lu Yang, Tao Li, Yafei Li, Zhongxing Jiang, Yanfang Liu, Chong Wang, Shujuan Wang
Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy
Jiayue Qiu, Xiangmei Li, Yalan He, Qian Wang, Ji Li, Jiashuo Wu, Ying Jiang, Junwei Han
Integrative metagenomic and metabolomic analyses reveal the role of gut microbiota in antibody-mediated renal allograft rejection
Xin Li, Ruoying Li, Bingqing Ji, Lili Zhao, Junpeng Wang, Tianzhong Yan
Pharmaceutical targeting Th2-mediated immunity enhances immunotherapy response in breast cancer
Yuru Chen, Jiazheng Sun, Yachan Luo, Jiazhou Liu, Xiaoyu Wang, Rui Feng, Jing Huang, Huimin Du, Qin Li, Jinxiang Tan, Guosheng Ren, Xiaoyi Wang, Hongzhong Li
Associations between life’s essential 8 and non-alcoholic fatty liver disease among US adults
Lili Wang, Jiayi Yi, Xinli Guo, Xiangpeng Ren
Diagnostic value of transpulmonary thermodilution measurements for acute respiratory distress syndrome in a pig model of septic shock
Yusuke Endo, Taku Miyasho, Kanako Endo, Yoshio Kawamura, Kenjiro Miyoshi, Ryosuke Takegawa, Takashi Tagami, Lance B. Becker, Kei Hayashida
C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2ʹ-O-methylation of PARP1
Bingfeng Lu, Xi Chen, Xin Liu, Jingwen Chen, Honglei Qin, Shuo Chen, Yang Zhao
Pre-neuromusculoskeletal injury Risk factor Evaluation and Post-neuromusculoskeletal injury Assessment for Return-to-duty/activity Enhancement (PREPARE) in military service members: a prospective, observational study protocol
Courtney M. Butowicz, Brad D. Hendershot, Nora L. Watson, Daniel I. Brooks, Donald L. Goss, Robert A. Whitehurst, Alisha D. Harvey, Matthew S. Helton, Joseph R. Kardouni, Matthew B. Garber, Timothy C. Mauntel
MTAP loss: a possible therapeutic approach for glioblastoma
C. Pawan K. Patro, Nupur Biswas, Sandeep C. Pingle, Feng Lin, Misa Anekoji, Lawrence D. Jones, Santosh Kesari, Feng Wang, Shashaanka Ashili
Mendelian randomization analyses in ocular disease: a powerful approach to causal inference with human genetic data
Jiaxin Li, Cong Li, Yu Huang, Peng Guan, Desheng Huang, Honghua Yu, Xiaohong Yang, Lei Liu
Protective effects of Gypenoside XVII against cerebral ischemia/reperfusion injury via SIRT1-FOXO3A- and Hif1a-BNIP3-mediated mitochondrial autophagy
Weijie Xie, Ting Zhu, Shuxia Zhang, Xiaobo Sun
Accurate genome-wide genotyping from archival tissue to explore the contribution of common genetic variants to pre-cancer outcomes
Daniela Nachmanson, Meghana Pagadala, Joseph Steward, Callie Cheung, Lauryn Keeler Bruce, Nicole Q. Lee, Thomas J. O’Keefe, Grace Y. Lin, Farnaz Hasteh, Gerald P. Morris, Hannah Carter, Olivier Harismendy
Retraction Note: Molecular analysis of the effects of Piroxicam and Cisplatin on mesothelioma cells growth and viability
Alessandra Verdina, Irene Cardillo, Angela Nebbioso, Rossella Galati, Simona Menegozzo, Lucia Altucci, Ada Sacchi, Alfonso Baldi
Non-invasive intravoxel incoherent motion MRI in prediction of histopathological response to neoadjuvant chemotherapy and survival outcome in osteosarcoma at the time of diagnosis
Esha Baidya Kayal, Sameer Bakhshi, Devasenathipathy Kandasamy, Mehar Chand Sharma, Shah Alam Khan, Venkatesan Sampath Kumar, Kedar Khare, Raju Sharma, Amit Mehndiratta
miR-4443 promotes radiation resistance of esophageal squamous cell carcinoma via targeting PTPRJ
Xiaobo Shi, Xiaoxiao Liu, Shan Huang, Yu Hao, Shupei Pan, Yue Ke, Wei Guo, Yuchen Wang, Hongbing Ma
KPNA2 promotes angiogenesis by regulating STAT3 phosphorylation
Yujie Jia, Qi Wang, Minglu Liang, Kai Huang
SAMHD1 silencing cooperates with radiotherapy to enhance anti-tumor immunity through IFI16-STING pathway in lung adenocarcinoma
Yangyi Li, Yuke Gao, Xueping Jiang, Yajie Cheng, Jianguo Zhang, Liexi Xu, Xinyu Liu, Zhengrong Huang, Conghua Xie, Yan Gong
Metabolomic profiles of metformin in breast cancer survivors: a pooled analysis of plasmas from two randomized placebo-controlled trials
Federica Bellerba, Anastasia Chrysovalantou Chatziioannou, Paniz Jasbi, Nivonirina Robinot, Pekka Keski-Rahkonen, Amarine Trolat, Béatrice Vozar, Sheri J. Hartman, Augustin Scalbert, Bernardo Bonanni, Harriet Johansson, Dorothy D. Sears, Sara Gandini
Cucurbitacins as potential anticancer agents: new insights on molecular mechanisms
Carla Varela, Catarina Melim, Beatriz G. Neves, Javad Sharifi-Rad, Daniela Calina, Assem Mamurova, Célia Cabral