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Herpes Virus 

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  1. Open Access 01-12-2024 | Human Alphaherpesvirus 3 | OriginalPaper

    The associations of herpes simplex virus and varicella zoster virus infection with dementia: a nationwide retrospective cohort study

    Dementia is the clinical diagnosis of acquired progressive decline in multiple cognitive domains requiring new functional dependence [ 1 , 2 ]. With an ageing global population, dementia is becoming a major social burden. According to the Global …

  2. Open Access 01-12-2024 | Alzheimer's Disease | OriginalPaper

    Human in vivo evidence of associations between herpes simplex virus and cerebral amyloid-beta load in normal aging

    Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder originated by a mixture of etiopathogenic mechanisms, which likely arise from complex interactions among genetics, lifestyle and environmental risk factors. Substantial …

  3. 23-02-2024 | Encephalitis | Online First

    Atypical Neuroimaging Features of Herpes Simplex Virus-2 Encephalitis

  4. Open Access 13-03-2024 | Herpes Simplex Type 1 | Online First

    RNA-Seq time-course analysis of neural precursor cell transcriptome in response to herpes simplex Virus-1 infection

    The neurogenic niches within the central nervous system serve as essential reservoirs for neural precursor cells (NPCs), playing a crucial role in neurogenesis. However, these NPCs are particularly vulnerable to infection by the herpes simplex …

  5. Open Access 01-12-2024 | Stem Cell Transplantation | OriginalPaper

    Retinitis after haematopoietic stem cell transplantation with multiple intraocular viral infections (cytomegalovirus, Epstein‒Barr virus and herpes simplex virus)- a case report

    Acute lymphocytic leukaemia is a blood malignancy caused by malignant proliferation of lymphocytes in the blood and bone marrow [ 1 ]. The manifestations of acute lymphoblastic leukaemia is vary. Chemotherapy and haematopoietic stem cell …

  6. Open Access 01-12-2024 | Herpes Simplex Encephalitis | OriginalPaper

    Herpes simplex virus infection induces necroptosis of neurons and astrocytes in human fetal organotypic brain slice cultures

    Various pathogens grouped under the acronym ‘TORCH’ [ Toxoplasma gondii , Others (e.g. parvovirus B and Zikavirus and Rubella virus), Cytomegalovirus and Herpes simplex viruses (HSV)], remain a substantial threat to newborns and fetuses worldwide [ …1

  7. 29-02-2024 | Hemophagocytic Lymphohistiocytosis | Online First

    Hemophagocytic lymphohistiocytosis caused by herpes simplex virus type 1 in a young adult: a case report with literature review

    Hemophagocytic lymphohistiocytosis is a severe hyperinflammatory syndrome that can be potentially life-threatening without appropriate treatment. Although viral infection is the most common trigger of hemophagocytic lymphohistiocytosis, cases of …

  8. Open Access 01-12-2024 | Herpes Virus | OriginalPaper

    Prunella vulgaris polysaccharide inhibits herpes simplex virus infection by blocking TLR-mediated NF-κB activation

    Prunella vulgaris is an herbaceous plant belonging to the Labiatae family that is commonly used in traditional Chinese medicine. The compounds and extracts isolated from P. vulgaris were reported to possess several potential pharmacological …

  9. 12-09-2023 | Epstein-Barr Virus | OriginalPaper

    Prevalence of Epstein Barr Virus and Herpes Simplex Virus Among Human Papillomavirus Negative Oral Cancer Patients: A Cross-Sectional Study from South India

    The high incidence of oral carcinomas is due to its multifactorial etiology and the presence of various risk factors. Human Papillomavirus (HPV) has a proven role in the pathogenesis of oral carcinomas, but in the recent times there has been an …

  10. Open Access 27-09-2023 | Cytokines | OriginalPaper

    Cytokine storm and severe hepatitis in pregnancy due to herpes simplex virus 2

    Herpes simplex virus (HSV) hepatitis is an uncommon disease primarily observed in immunocompromised individuals and pregnant women frequently leading to adverse outcomes. It represents a challenging diagnosis due to its non-specific clinical …

  11. 01-12-2023 | OriginalPaper

    Augmented antiviral activity of chlorhexidine gluconate on herpes simplex virus type 1, H1N1 influenza A virus, and adenovirus in combination with salicylic acid

    The use of biocides (antiseptics, disinfectants, and preservatives) has expanded worldwide, especially for applications that do not necessarily need them, including cleaning of households and offices. Excessive discharge of these compounds into …

  12. 01-01-2024 | Herpes Virus | Report

    Understanding the Medical Dictionary for Regulatory Activities (MedDRA) reporting of herpes simplex virus (HSV) adverse events in atopic dermatitis clinical trials

    Drug efficacy is best evaluated by randomized, controlled, double-blind clinical trials; however, safety is harder to assess. The Medical Dictionary for Regulatory Activities (MedDRA) is used to track and categorize adverse events (AE) during …

  13. Open Access 01-12-2023 | Herpes Virus | OriginalPaper

    A case of herpes simplex virus induced peripheral neuropathy and encephalitis with positive GM3 and CASPR2 antibody

    The herpes virus can establish a latent infection in the host and cause recurring disease when reactivation occurs. Of the herpes viruses currently identified, the neurotropic herpes simplex virus type 1 (HSV-1) can invade the central nervous …

  14. 05-09-2023 | Herpes Virus | OriginalPaper

    Herpes simplex virus keratitis: electronic medical records driven big data analytics report from a tertiary eye institute of South India

    Herpes simplex keratitis (HSK) is one of the most common causes of corneal blindness in the developed world [ 1 ] however it is still underreported [ 2 ] in literature due to the lack of defined criteria for diagnosis, low awareness, relatively …

  15. Open Access 01-12-2023 | Shingles | OriginalPaper

    Herpes Virus Infections in Kidney Transplant Patients (HINT) – a prospective observational cohort study

    For a selected group of patients with chronic kidney failure, kidney transplantation is the best treatment modality. After transplantation, kidney transplant recipients receive life-long immunosuppressive maintenance therapy to avoid rejection of …

  16. 23-10-2023 | Herpes Virus | BriefCommunication

    Severe acute herpes virus type 2 primo-infection and its association with anti-type 1 interferon autoantibodies

    Herpes simplex virus type 2 (HSV-2) is a common cause of infection, which is usually self-limited and asymptomatic. A 71-year-old patient with HSV-2 primo-infection developed acute hepatitis and secondary hemophagocytic lymphohistiocytosis. The …

  17. Open Access 01-12-2023 | Kaposi's Sarcoma-Associated Herpesvirus | OriginalPaper

    Comparison of Epstein–Barr virus and Kaposi’s sarcoma-associated herpesvirus viral load in peripheral blood mononuclear cells and oral fluids of HIV-negative individuals aged 3–89 years from Uganda

    We previously found that age, sex and malaria were associated with KSHV in individuals from Uganda. In this study, we have evaluated these same factors in relation to EBV in the same specimens. Overall, 74% (oral fluids) and 46% (PBMCs) had …

  18. Open Access 01-12-2023 | Shingles | OriginalPaper

    Herpes zoster associated with stroke incidence in people living with human immunodeficiency virus: a nested case–control study

    Stroke is the second most common cause of death resulting in a significant health burden worldwide [ 1 ]. In 2019, global stroke incidence increased by 70%, its mortality by 43%, and disability-adjusted life-years (DALYs) due to stroke by 32% [ 2 …

  19. Open Access 01-12-2023 | Herpes Virus | OriginalPaper

    Association between human herpes simplex virus and periodontitis: results from the continuous National Health and Nutrition Examination Survey 2009–2014

    The human herpes simplex virus (HSV), which includes HSV-1 and HSV-2, belongs to the alpha (α) subfamily of the Herpesviridae family [ 1 ]. Herpesvirus virions include a DNA molecule, an icosahedral capsid, a proteinaceous tegument, and an envelope …

  20. Open Access 13-09-2023 | Shingles | Report

    Varicella Zoster Virus-Specific Hyperimmunoglobulin in the Adjuvant Treatment of Immunocompromised Herpes Zoster Patients: A Case Series

    Herpes zoster (HZ) is a painful disease caused by reactivation of the varicella zoster virus (VZV) from latently infected ganglionic neurons [ 1 ]. Despite mainstay therapy with early systemic antiviral agents and analgesics, zoster patients are at …

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