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Obstetrics and Gynecology

Reassuring results for ART use in BRCA breast cancer survivors

The use of assisted reproductive technology to conceive after breast cancer in young BRCA1/2 carriers does not appear to worsen disease-free survival or pregnancy outcomes.

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Editor's Choice

Managing bone metastases in gynecologic malignancies

Bone metastases occur in 1–23% of gynecologic cancer patients. What are the available pharmacologic, surgical, and radiation treatments for palliation and the prevention of skeletal-related events in this population?

IL-6 shows promise as diagnostic biomarker for sepsis

Interleukin-6 shows promise as a biomarker to diagnose sepsis early in high-risk patient groups such as neonates, children, and pregnant women.

Menopause and migraine

How do fluctuations in female sex hormones contribute to migraine attacks during menopause and perimenopause, and how can you best help to manage them?

Half-dose apixaban for cancer patients at risk for recurrent VTE

Patients requiring extended thromboprophylaxis after a first episode of cancer-related venous thromboembolism can be given a low dose of the factor X inhibitor apixaban.

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Women’s health knowledge hub

Elevate your patient care with our comprehensive, evidence-based medical education on women's health. Designed to help you provide exceptional care for your female patients at every stage of life, we provide expert insights into topics such as reproductive health, menopause, breast cancer and sex-specific health risks and precision medicine.

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Case Studies

Complete androgen insensitivity syndrome in a twin girl

An 18-year-old girl who presented for primary amenorrhea treatment was found to have a 46, XY karyotype. CAIS was diagnosed and treated. Her twin brother had a 46, XY karyotype with male physical and ultrasound features.

Synchronous breast cancer and pleural mesothelioma

A woman who underwent mastectomy and chemotherapy for breast cancer subsequently developed chest pain and dyspnea. Would you have considered pleural mesothelioma as the cause?

Pregnancy-related aortic dissection mistaken for anxiety

Dyspnea, chest pain and palpitations were initially attributed to an anxiety disorder in a pregnant woman. A chest CT revealed signs of chronic type A aortic dissection.

At a glance: The DESTINY-Breast trials

The antibody–drug conjugate trastuzumab deruxtecan is being investigated in the DESTINY-Breast trials for the treatment of breast cancer.

Developed by: Springer Medicine
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Current Reviews

Scoping review on the embryonic developmental potential of tripronuclear zygotes and their use for clinical and research purposes

We reviewed the published literature on human 3PN zygotes, focusing on their developmental potential, genetic status, and possible correction, either spontaneous (autocorrection) or through micromanipulation. A total of 29 articles published …

Therapy of early breast cancer: current status and perspectives

Medical advancements in breast cancer are truly remarkable. Especially in recent years, numerous new therapeutics have been approved and surgical strategies have been de-escalated for specific patient groups. In the therapeutic setting, CDK4/6 …

Safety of laparoscopic surgery for ovarian tissue cryopreservation in pediatric patients

In recent years, fertility preservation (FP) has become more common worldwide, and the number of procedures being performed in Japan has also been increasing. Ovarian tissue cryopreservation (OTC) is one option for FP in children [ 1 ]. As of the …

Cardio-Oncology and Breast Cancer Therapies

Assessing cardiac risk prior to initiating breast cancer treatment, monitoring cardiac function during treatment, and implementing appropriate follow-up strategies are essential components of managing cardiotoxicity in breast cancer patients. A …

Episode 16: Sexual health in older age

Normalizing sexual wellbeing throughout adulthood

Roughly 50% of women over 50 experience sexual dysfunction, yet fewer than 20% report it to their doctor, thinking these changes are 'just part of aging'.

As doctors, we should be helping women lead sexually healthy and fulfilling lives as they age. Prof Holly Thomas tells us how.

Prof. Holly Thomas
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Podcast

CME & eLearning

Patient Cases

Take on interactive case studies with a focus on hematology. Each case has been prepared by renowned experts in the field and features knowledge-check questions with answers to help keep you and your practice up to date.

Developed by: Springer Medizin

Further Reading

Responsiveness and minimal important change of neck disability index and numeric pain rating scale for neck patients in the Norwegian neck and back register

Neck pain is one of the leading causes for seeking healthcare [ 1 ]. In the latest Lancet Global burden of disease, neck pain is ranked as the eight highest cause of years lived with disability among women, and twelfth for men [ 2 ], and with the …

Sexually Transmitted Infection (STI) Incidence and Risk Factors Among People with HIV (PWH): Insights from a 13-Year Cohort Study in South Carolina

The Ending the HIV Epidemic (EHE) initiative aims to reduce new HIV infections by 90% by 2030 in the United States (US). However, rising sexually transmitted infection (STI) rates exacerbate the bidirectional infection risk between HIV and STIs.

Distinct endometriosis involvement confers divergent oncologic outcomes in ovarian clear cell carcinoma

Endometriosis is a chronic, estrogen-dependent, inflammatory disorder characterized by ectopic endometrial glands and stroma, affecting approximately 10% of reproductive-aged women [ 1 ]. Despite its benign nature, the chronic inflammation and …

Comprehensive Analysis and Leveraging Online Innovations to Improve HIV and STI Prevention and Treatment Services in Major Cities of Thailand

Despite a 50% reduction in new HIV cases since 2010, HIV and sexually transmitted infections (STIs) remain pressing public health challenges in Thailand, particularly among marginalized and high-risk populations. This study examined 8,865 bookings …