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Diabetic Nephropathy 

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  1. Open Access 01-12-2024 | Diabetic Nephropathy | OriginalPaper

    Improvement effects of transplanting pancreatic islet that previously incubated with biomaterials on the diabetic nephropathy in STZ- diabetic rats

    Diabetic nephropathy (DN) is very common in both type 1 and type 2 diabetic patients [ 1 , 2 ] and can be noted from onset to the last stage of diabetes [ 3 ]. Pathophysiological changes in DN hallmarks include glomerular basement membrane GBM …

  2. 25-04-2024 | Diabetic Nephropathy | Online First

    Non-diabetic nephropathy in diabetic patients: incidence, HbA1c variability and other predictive factors, and implications

    Diabetes mellitus (DM) is a significant public health concern in both industrialized and developing nations. Based on data from 2019, it was reported that 9.3 percent of the population, or 463 million individuals, were diagnosed with diabetes [ 1 …

  3. Open Access 01-12-2024 | Diabetic Nephropathy | OriginalPaper

    Causal effect of gut microbiota and diabetic nephropathy: a Mendelian randomization study

    Diabetes mellitus (DM) is one of the most common and fastest growing chronic diseases worldwide and it is estimated that there will be 642 million people with DM in 2040 [ 1 ]. Diabetic nephropathy (DN), one of the microvascular complications of …

  4. Open Access 01-12-2024 | Diabetic Nephropathy | OriginalPaper

    Artificial intelligence assists identification and pathologic classification of glomerular lesions in patients with diabetic nephropathy

    Diabetic nephropathy (DN) is one of the main causes of chronic kidney disease worldwide [ 1 ]. Patients with DN are characterized by continuously progressive proteinuria and renal function decline, and most of them are diagnosed with clinical …

  5. 19-01-2024 | Diabetic Nephropathy | Letter

    Susceptibility to diabetic nephropathy

  6. Open Access 19-01-2024 | Diabetic Nephropathy | Letter

    Response to “Susceptibility to diabetic nephropathy

  7. 15-04-2024 | Diabetic Nephropathy | Online First

    Role of serum pentraxin-3 levels in patients with and without diabetic nephropathy

    The prevalence of diabetes is increasing worldwide, with the greatest increase seen in countries with low and middle socioeconomic status [ 1 ]. It has been estimated that by the year 2045, around 783.2 million people will be diagnosed with …

  8. 10-01-2024 | Diabetic Retinopathy | Letter

    Differences in effects of some newer-generation anti-diabetics on diabetic retinopathy versus nephropathy

  9. 23-04-2024 | Diabetic Nephropathy | Online First

    Astragalus polysaccharide attenuates diabetic nephropathy by reducing apoptosis and enhancing autophagy through activation of Sirt1/FoxO1 pathway

    Diabetic nephropathy (DN) is a common complication of type 2 diabetes [ 1 ]. The clinical manifestations in DN patients at an early stage are proteinuria and glomerular hyperfiltration [ 2 ]. Podocyte injury is a pathological feature of proteinuria …

  10. Open Access 01-12-2024 | Diabetic Nephropathy | OriginalPaper

    Navigating the future of diabetes: innovative nomogram models for predicting all-cause mortality risk in diabetic nephropathy

    Diabetes is a chronic, non-communicable, multisystemic disease characterized by elevated blood glucose levels due to the body’s inability to effectively produce or utilize insulin [ 1 , 2 ]. According to statistics, in 2021, approximately 529 …

  11. Open Access 01-12-2024 | Diabetic Nephropathy | OriginalPaper

    Depression of LncRNA DANCR alleviates tubular injury in diabetic nephropathy by regulating KLF5 through sponge miR-214-5p

    The global incidence of kidney disease-related deaths is on a concerning upward trajectory [ 1 ]. Diabetic nephropathy (DN) also named diabetic kidney disease (DKD), stands as the most prevalent microvascular complication associated with diabetes …

  12. 06-12-2023 | Diabetic Nephropathy | OriginalPaper

    Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy

    Diabetic nephropathy (DN) is a common diabetic complication. Studies show that mitophagy inhibition induced-ferroptosis plays a crucial role in DN progression. UHRF1 is associated with mitophagy and is highly expression in DN patients, however …

  13. 17-04-2024 | Amyloidosis | Online First

    ALECT2 amyloidosis with concurrent IgG4-related interstitial nephritis, membranous nephropathy and diabetic kidney disease: a case report and literature review

    Leukocyte chemotactic factor-2 amyloidosis (ALECT2) is a recently described subtype of amyloidosis. IgG4-related disease is a rare fibroinflammatory condition characterized by dense interstitial lymphoplasmacytic infiltrates and fibrosis.

  14. 23-03-2024 | Diabetic Nephropathy | Online First

    The causal effect of inflammatory proteins and immune cell populations on diabetic nephropathy: evidence from Mendelian randomization

    Diabetic nephropathy (DN), as one of the diabetic microvascular complications, is a major sequela of the epidemic of diabetes mellitus worldwide [ 1 ]. A cross-sectional study based on the National Health and Nutrition Examination Survey (NHANES) …

  15. Open Access 01-12-2024 | Diabetic Nephropathy | OriginalPaper

    ITGAM-mediated macrophages contribute to basement membrane damage in diabetic nephropathy and atherosclerosis

    Diabetic nephropathy (DN) represents a prevalent and serious complication of diabetes mellitus (DM), contributing to heightened mortality rates among individuals affected by diabetes [ 1 ]. Hyperglycemia is considered to be the most important risk …

  16. 29-10-2023 | Microalbuminuria | ReviewPaper

    Evaluation of N-acetyl-β-D-glucosaminidase as a prognostic marker for diabetic nephropathy in type 2 diabetics: systematic review and meta-analysis

    Diabetes mellitus (DM) continues to be a significant global public health concern, with an estimated 537 million individuals affected worldwide [ 1 ]. Type 2 diabetes mellitus (T2DM) accounts for 90–95% of these cases. T2DM is a chronic metabolic …

  17. 19-12-2023 | Diabetic Retinopathy | ReviewPaper

    Biomarkers and signaling pathways of diabetic nephropathy and peripheral neuropathy: possible therapeutic intervention of rutin and quercetin

    Diabetic nephropathy and peripheral neuropathy are the two main complications of chronic diabetes that contribute to high morbidity and mortality. These conditions are characterized by the dysregulation of multiple molecular signaling pathways and …

  18. 12-02-2024 | Diabetic Nephropathy | Online First

    Exosomal UMOD gene expression and urinary uromodulin level as early noninvasive diagnostic biomarkers for diabetic nephropathy in type 2 diabetic patients

    Diabetic nephropathy (DN) is one of the major microvascular complications of diabetes and most frequently results in end-stage renal disease (ESRD). DN is characterized pathophysiologically by an early phase of glomerular hypertrophy …

  19. 26-08-2023 | Diabetic Nephropathy | OriginalPaper

    Serum soluble α-Klotho levels in patients with diabetic nephropathy

    The Klotho gene has been identified as a gene that inhibits the aging process and promotes longevity when its expression is enhanced, but accelerates aging when it is disrupted [ 1 ]. This gene is primarily expressed as a transmembrane protein in …

  20. Open Access 01-12-2024 | Diabetic Nephropathy | OriginalPaper

    SGLT2i relieve proteinuria in diabetic nephropathy patients potentially by inhibiting renal oxidative stress rather than through AGEs pathway

    As one of the most frequent and severe complications of diabetes mellitus (DM), diabetic nephropathy (DN) is an important cause of end-stage renal disease and is recognized as a public health problem worldwide. On a global scale, the incidence and …

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