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Pre-Eclampsia 

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  1. Open Access 01-12-2024 | Pre-Eclampsia | OriginalPaper

    Assessing pre-eclampsia awareness among pregnant women in Syria: a cross-sectional study on knowledge and perceptions

    Preeclampsia (PE) is characterized by high blood pressure and proteinuria at 300 mg/day in pregnant women [ 1 ]. This condition is one of the primary causes of maternal and child mortality in low-income countries and is accompanied by symptoms …

  2. 26-03-2024 | Pre-Eclampsia | Online First

    Expression of long non-coding RNA GAS5 by first trimester screening predicts the occurrence of gestational hypertension and pre-eclampsia

    Hypertensive disorders of pregnancy (HDP) are multisystem disorders unique to human pregnancy, emerging after 20 weeks of gestation [ 1 ]. HDP is characterized by hypertension, albuminuria, edema, and multiple organ damage [ 2 ]. HDP seriously …

  3. Open Access 01-12-2024 | Pre-Eclampsia | OriginalPaper

    Effects of calcium supplementation on changes in the IL2, IL4, IL6, IL10 axes and oxidative stress in pregnant women at risk for pre-eclampsia

    Normal fetal development depends on maternal hemodynamics and on cardiovascular changes to meet the increasing oxygen and nutrient demands [ 1 ]. Alterations in these adaptive changes can develop gestational hypertensive disorders that affect from …

  4. 31-10-2023 | Pre-Eclampsia | OriginalPaper

    Mid-Trimester Spot Urinary Albumin/Creatinine Ratio as a Screening Tool in Prediction of Pre-eclampsia

    Preeclampsia (PE) is a pregnancy-specific disorder affecting all the organ systems. Research is going on for a cost-effective, rapid and convenient test to predict preeclampsia to prevent complications. ACOG Task Force on Hypertension in Pregnancy …

  5. 11-11-2023 | Pre-Eclampsia | OriginalPaper

    Correlation of Serum Cancer Antigen-125 (CA-125) Levels with Severity of Pre-eclampsia

    Pre-eclampsia is a pregnancy-associated multifactorial, multi-systemic progressive disease occurring mainly following 20 weeks of gestation. It is distinguished by the presence of new-onset hypertension with proteinuria or considerable end-organ …

  6. Open Access 01-12-2023 | Pre-Eclampsia | OriginalPaper

    Pre-eclampsia during pregnancy and risk of endometrial cancer: a systematic review and meta-analysis

    The incidence of endometrial cancer has increased rapidly in high-income countries [ 1 ], doubling in the UK over the last 30 years [ 2 ] and in the US, a 0.5% increase in age-adjusted rates has been observed year-on-year [ 3 ]. Rising incidence …

  7. Open Access 01-12-2023 | Pre-Eclampsia | OriginalPaper

    Alpha-2-macroglobulin is involved in the occurrence of early-onset pre-eclampsia via its negative impact on uterine spiral artery remodeling and placental angiogenesis

    As a multifactorial disorder, PE is a serious blood pressure condition associated with excessive proteinuria or organ dysfunction in pregnant women after the 20th week of pregnancy; its pathological mechanism is poorly understood to date [ 1 , 2 ].

  8. 21-07-2023 | Pre-Eclampsia | OriginalPaper

    Performance of HDP-Gestosis Score and Ophthalmic Artery Doppler in Prediction of Pre-eclampsia

    The incidence of Pre-eclampsia in India is 14% and is one of the leading cause of maternal mortality and morbidity in developing countries [ 1 ].

  9. Open Access 01-12-2023 | Pre-Eclampsia | OriginalPaper

    Integrated bioinformatic analysis reveals NOS2 as a novel ferroptosis-related biomarker for pre-eclampsia

    Pre-eclampsia (PE), characterized by organ damage and hypertension after 20 gestational weeks, has a prevalence of 2–8%. PE is associated with short-term complications such as cardiac, hepatic, pulmonary, renal, and neurological dysfunction, and …

  10. 28-09-2022 | Hypertension | OriginalPaper

    Urine Calcium–Creatinine Ratio in Prediction of Pre-eclampsia

    Hypertensive disorders of pregnancy are first identified during pregnancy (gestational hypertension, pre-eclampsia, eclampsia, and HELLP syndrome) or may present as a complication of previously existing disease (chronic hypertension, renal …

  11. Open Access 01-12-2022 | Pre-Eclampsia | ReviewPaper

    Diagnostic biomolecules and combination therapy for pre-eclampsia

    Pre-eclampsia (PE), associated with placental malperfusion, is the primary reason for maternal and perinatal mortality and morbidity that can cause vascular endothelial injury and multi-organ injury. Despite considerable research efforts, no …

  12. 18-04-2023 | Eclampsia | EditorialNotes

    Commentary: magnetic resonance spectroscopy and liquid chromatography-mass spectrometry metabolomics study may differentiate pre-eclampsia from gestational hypertension

  13. 15-06-2023 | Pre-Eclampsia | OriginalPaper

    Evaluating the characteristics of myocardial work by two-dimensional echocardiography during pre-eclampsia pregnancy

    This study aimed to analyze the changes in myocardial work (MyW) properties and the correlation of MyW with cardiovascular and clinical indices during the pre-eclampsia (PE) pregnancy. Standard two-dimensional and speckle-tracking echocardiography …

  14. 21-02-2023 | Magnetic Resonance Imaging | OriginalPaper

    Magnetic resonance spectroscopy and liquid chromatography-mass spectrometry metabolomics study may differentiate pre-eclampsia from gestational hypertension

    Hypertensive disorders of pregnancy (HDP) are a serious threat to maternal and infant health and are currently the leading causes of maternal mortality. HDP are classified into five subcategories [ 1 ]: (1) gestational hypertension (GH); (2) …

  15. Open Access 01-12-2022 | Eclampsia | OriginalPaper

    Association between gut microbiota and preeclampsia-eclampsia: a two-sample Mendelian randomization study

    Preeclampsia and eclampsia (PE) are serious complications of pregnancy that affect 3–8% of pregnancies worldwide [ 1 , 2 ] and are the leading causes of maternal and neonatal death [ 3 , 4 ]. PE increases the risk of adverse pregnancy outcomes …

  16. Open Access 01-12-2022 | Chloroquin | OriginalPaper

    Systematic evaluation of the pre-eclampsia drugs, dietary supplements and biologicals pipeline using target product profiles

    Pre-eclampsia and eclampsia, the most common hypertensive disorders of pregnancy, are a leading cause of maternal mortality, affecting approximately 4.6% of pregnant women [ 1 ] and resulting in approximately 14% of maternal deaths worldwide [ 2 …

  17. Open Access 01-12-2022 | Chronic Lymphocytic Leukemia | OriginalPaper

    A case report of pre-eclampsia-like endothelial injury in the kidney of an 85-year-old man treated with ibrutinib

    Chronic lymphocytic leukemia (CLL) is the most common chronic leukemia in adults in the United States and Europe [ 1 ]. Despite the relative frequency of CLL, renal complications of CLL are uncommon. Membranoproliferative glomerulonephritis (MPGN) …

  18. Open Access 01-12-2022 | Pre-Eclampsia | OriginalPaper

    Placental growth fActor Repeat sampling for Reduction of adverse perinatal Outcomes in women with suspecTed pre-eclampsia: study protocol for a randomised controlled trial (PARROT-2)

    Hypertension affects 10% of pregnant women, with pre-eclampsia affecting 2.8% of singleton pregnancies [ 1 ]. Forty per cent of all pre-eclampsia occurs preterm [ 2 ] and 12% before 34 weeks’ gestation [ 3 ], and preterm pre-eclampsia is more …

  19. Open Access 01-12-2021 | Thrombocytopenia | OriginalPaper

    Mild thrombocytopenia indicating maternal organ damage in preeclampsia: a cross‐sectional study

    Hypertensive disorders of pregnancy (HDP) can cause hypertension and maternal organ damage due to endothelial dysfunction [ 1 , 2 ]. Among patients with HDP, women who develop maternal organ damage in addition to hypertension are diagnosed with …

  20. Open Access 01-12-2023 | Eclampsia | OriginalPaper

    Advanced tubal pregnancy at 34 weeks with eclampsia and HELLP syndrome: a case report and literature re

    Tubal pregnancy, which accounts for 94% of all ectopic pregnancies [ 1 ], is always treated early for the typical clinical manifestations of amenorrhea, bleeding, and abdominal pain, as well as massive intraperitoneal hemorrhage. Almost 80% of them …

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