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Open Access Diabetes Review

Diabesity, stress, and cancer risk

Explore the relationship between emotional wellbeing, metabolic health, and the risk of developing cancer. Learn how stress may worsen the increased cancer risk in people with diabetes, obesity, or both.

Overlooked effect of angiotensin receptor–neprilysin inhibitor

Free for a limited time Medical Side Effect Case Study

Caution is needed when assessing insulin secretion capability and nephropathy in patients with diabetes who are being treated with an angiotensin receptor–neprilysin inhibitor.

Cardiorenal benefits of semaglutide in type 2 diabetes with CKD

05-06-2024 Type 2 Diabetes News

Semaglutide has renal and cardioprotective effects in people with type 2 diabetes and chronic kidney disease who are at high risk for complications. 

Measuring ketone bodies

Free for a limited time Ketoacidosis Review

Measurement of ketones is encouraged to aid the diagnosis and assessment of diabetic ketoacidosis, but which method should be used: urine analysis, blood testing, or measurement of breath acetone?

Near-lifelong benefits of early intensive glycemic control

30-05-2024 Type 2 Diabetes News

The benefits of early intensive glycemic control in people with newly diagnosed type 2 diabetes have persisted for up to 24 years since the UKPDS trial ended.

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Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Overlooked effect of angiotensin receptor–neprilysin inhibitor

Free for a limited time Medical Side Effect Case Study

Caution is needed when assessing insulin secretion capability and nephropathy in patients with diabetes who are being treated with an angiotensin receptor–neprilysin inhibitor.

DPP4 inhibitors a cause of IgG4-related kidney disease?

Free for a limited time Interstitial Nephritis Case Study

A man with type 2 diabetes and IgG4-related kidney disease developed bullous pemphigoid. DPP4 inhibitor treatment, which also correlated with changes in renal function, was discontinued.

Managing exogenous insulin antibody syndrome

Open Access Type 1 Diabetes Case Study

EIAS can cause hyperglycemia, hypoglycemia, and ketoacidosis in people with diabetes. This case in an older adult with type 1 diabetes shows how EIAS can be managed in an outpatient setting.

Using CGM to optimize type 2 diabetes management with non-intensive insulin treatment in primary care

With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report. 

Supported by: Abbott Diabetes Care

Prof. Samuel Seidu
Developed by: Adis

Current Reviews

GLP1-GIP receptor co-agonists: a promising evolution in the treatment of type 2 diabetes

Open Access Tirzepatide Review

Type 2 diabetes represents a growing challenge for global public health. Its prevalence is increasing worldwide, and, like obesity, it affects progressively younger populations compared to the past, with potentially greater impact on chronic …

Evidence-based definition of hypoprolactinemia in European men aged 40–86 years: the European male ageing study

Open Access Type 2 Diabetes

Empirical evidence for a low normal or reference interval for serum prolactin (PRL) is lacking for men, while the implications of very low PRL levels for human health have never been studied. A clinical state of “PRL deficiency” has not been …

GLP-1 Receptor Agonists and Cardiovascular Disease: What Do Clinicians Need to Know?

Cardiovascular diseases (CVDs), including ischemic heart disease, stroke, heart failure (HF) and peripheral arterial disease (PAD), remain one of the most important causes of increased global morbidity and mortality [ 1 ]. In the past decade, CVDs …

The insulin secretory granule is a hotspot for autoantigen formation in type 1 diabetes

Insulins Review

In type 1 diabetes, the insulin-producing beta cells of the pancreas are destroyed through the activity of autoreactive T cells. In addition to strong and well-documented HLA class II risk haplotypes, type 1 diabetes is associated with noncoding …

Episode 10: Disease-modifying therapy for type 1 diabetes

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu
Insulins Clinical Trial Summary

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.

Developed by: Springer Medicine

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Vodcasts | Case Scenarios (Link opens in a new window)

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

eLearning | Infographics (Link opens in a new window)

An independent educational program featuring simulated patient consultations. Make knowledge-based decisions on diagnosis and management of CKD with and without co-morbidities, and learn from experts Kevin Fernando and David Wheeler.

Supported by:
  • AstraZeneca
Developed by: Springer Healthcare IME

Further Reading

Safety and effectiveness of SGLT2 inhibitors in a UK population with type 2 diabetes and aged over 70 years: an instrumental variable approach

Open Access Infection of the Genital Organs Original Research

Current type 2 diabetes guidelines recommend an individualised approach to treatment that takes into account preferences, comorbidities, risks from polypharmacy, and the likelihood of long-term benefit from interventions [ 1 , 2 ], but clear …

Assessment of bone marrow edema on dual-energy CT scans in people with diabetes mellitus and suspected Charcot neuro-osteoarthropathy

Open Access Edema Scientific Article

Charcot neuro-osteoarthropathy (CN) is one of the most severe complications of diabetic peripheral polyneuropathy. CN is relatively uncommon with an incidence of 0.1–0.3% in the diabetic population and is therefore often not a diagnosis that …

Effectiveness of the flash glucose monitoring system in preventing severe hypoglycemic episodes and in improving glucose metrics and quality of life in subjects with type 1 diabetes at high risk of acute diabetes complications

Open Access Type 1 Diabetes Original Article

Type 1 diabetes (T1D) accounts for almost 10% of overall diabetes with a growing 3–5% annual incidence [ 1 ]. Intensive glucose management delays the onset and slows the progression of microvascular [ 2 ] and macrovascular long-term complications [ …3

Gestational Diabetes Risk and Low Birth Weight After Metabolic Bariatric Surgery: a Complex Interplay to be Balanced

Open Access Gestational Diabetes Original Contributions

In parallel to the rising prevalence of obesity in the general population, the prevalence of obesity in women during pregnancy is also increasing, which is estimated to range between 7 and 25% in Europe [ 1 , 2 ]. Women with obesity are at …

Related topics

Diabesity, stress, and cancer risk

Open Access Diabetes Review

Explore the relationship between emotional wellbeing, metabolic health, and the risk of developing cancer. Learn how stress may worsen the increased cancer risk in people with diabetes, obesity, or both.

Read more

Measuring ketone bodies

Free for a limited time Ketoacidosis Review

Measurement of ketones is encouraged to aid the diagnosis and assessment of diabetic ketoacidosis, but which method should be used: urine analysis, blood testing, or measurement of breath acetone?

Read more