Diabetology

Traditionally, adipose tissue was thought a passive energy storage depot simply, playing a fundamental role in energy homeostasis. In 1993, Hotamisligil et al. found the expression of TNF-α in adipose tissue, which was thought closely associated …

Adverse pregnancy outcomes (APOs), which include hypertensive disorders of pregnancy (HDP), gestational diabetes (GDM), preterm birth (PTB), low birthweight (LBW), along with peripartum cardiomyopathy (PPCM) are key risk factors for the …

Type two Diabetes Mellitus (T2DM) is a rising epidemic. Available therapeutic strategies have provided glycaemic control via HbA1c reduction but fail to provide clinically meaningful reduction in microvascular and macrovascular (cardiac, renal …

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus precipitated a new infectious diseases pandemic, with > 650 million cases and > 6.6 million deaths worldwide [ 1 ]. This new pandemic overlaps the current metabolic pandemics …

Diabetes is a complex chronic condition affecting 11.3% of the US population, amounting to 37.3 million people living with diabetes in 2019 [ 1 ]. With estimated total combined direct healthcare and lost productivity costs of $327 billion in 2017 …

Impaired myocardial mechano-energetics efficiency (MEE) was shown to predict incident heart failure, but pathophysiological mechanisms linking impaired MEE with heart failure have not been elucidated. Endothelial dysfunction is a plausible …

Changes in cardiovascular risk factors through the past decades have previously been studied, showing generally lower levels of major risk factors, such as smoking and hyperlipidemia, but increasing rates of obesity [ 1 – 4 ]. In a Swedish male …

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus precipitated a new infectious diseases pandemic, with > 650 million cases and > 6.6 million deaths worldwide [ 1 ]. This new pandemic overlaps the current metabolic pandemics …