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Disordered sleep and painful diabetic neuropathy

Pain symptoms from PDN can disrupt sleep, and disordered sleep can exacerbate pain. Learn about promising treatments for disordered sleep in people with PDN and the efficacy of treatments in improving pain and/or sleep quality.

Read more

Editor's Choice

YKL-40 linked to GI cancer risk in type 2 diabetes

Raised YKL-40 levels are associated with an increased risk for obesity-related and gastrointestinal cancers, particularly liver cancer, in people with type 2 diabetes.

Skin infection or lymphoma in a woman with type 2 diabetes?

Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.

The threat of childhood obesity

Childhood obesity is a growing global health concern, but how should obesity be defined and measured in children, and how does it impact health in the short and long term?

Clinical use of polygenic scores in type 2 diabetes

Explore the clinical potential of type 2 diabetes-related PGSs for risk prediction and screening of type 2 diabetes and its comorbidities and risk stratification, with attention to their global applicability.

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Keynote series | Spotlight on managing health in obesity

Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.

Prof. Eva L. Feldman
Prof. Jonette Keri
Developed by: Springer Medicine
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Video

Using CGM to optimize type 2 diabetes management with non-intensive insulin treatment in primary care

With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report. 

Supported by:
  • Abbott Diabetes Care
Prof. Samuel Seidu
Developed by: Adis
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Podcast

Case Studies

Skin infection or lymphoma in a woman with type 2 diabetes?

Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.

Colonic ischemia associated with a GLP-1 RA

Although it seems to be a rare complication, there should be a high index of suspicion for colonic ischemia in patients taking a GLP-1 receptor agonist who present with abdominal pain.

Non-islet cell tumor hypoglycemia and sarcoma

NICTH was diagnosed in a man with pelvic sarcoma. Severe hypoglycemia did not respond to standard treatments but had a partial response to rhGH and angioembolization of the tumor.

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
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Current Reviews

Managing diabetic cardiomyopathy without drugs

Treating cardiac dysfunction in diabetic cardiomyopathy remains challenging. Without useful drug therapies, are exercise and dietary strategies the best way to manage cardiac outcomes in DCM patients?

Dose-dependent effects of omega-3 polyunsaturated fatty acids on C-reactive protein concentrations in cardiometabolic disorders: a dose–response meta-analysis of randomized clinical trials

C-reactive protein (CRP) has been shown to be one of the top biomarkers for predicting future primary and secondary cardiovascular events and is one of the most studied biomarkers (Arroyo-Espliguero et al. 2021 ; van Holten et al. 2013 ). The …

Applications of generative adversarial networks in the diagnosis, prognosis, and treatment of ophthalmic diseases

The integration of artificial intelligence (AI) into ophthalmology has the potential to revolutionize ocular disease diagnosis, management, and treatment; to facilitate earlier, more effective interventions; and to enhance patient clinical …

Advancing toward a curative frontier: an updated narrative review on stem-cell therapy in pediatric type 1 diabetes

Type 1 diabetes (T1D) remains one of the most prevalent chronic illnesses diagnosed in childhood, and is an immune-mediated disease directed against pancreatic β-cells, resulting in severe endogenous insulin deficiency and subsequent hyperglycemia …

Episode 10: Disease-modifying therapy for type 1 diabetes

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu
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Podcast

CME & eLearning

Videos | Case Scenarios | Infographics (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)

Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Vodcasts | Case Scenarios (Link opens in a new window)

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

News | Expert Reviews | Cases (Link opens in a new window)

Treating children with hormone disorders is complex and requires tailored management. To help you provide the most effective care, we deliver resources covering adrenal, thyroid, pituitary, growth, and puberty disorders, obesity, and diabetes.

Supported by:
  • Merck Healthcare KGaA, Darmstadt, Germany
Developed by: Springer Healthcare IME

Further Reading

Hyperglycemia and kidney outcomes in critically ill children and young adults on continuous kidney replacement therapy

Hyperglycemia is common in critically ill children and adults [ 1 – 3 ] as is acute kidney injury (AKI) [ 4 ]. There is a bidirectional relationship between the pathogenesis of altered glucose metabolism and AKI, as aberrant glucose metabolism …

Metformin Prescription Orders among Patients with Prediabetes in a National Network of Federally Qualified Health Centers

Prediabetes represents a high-risk state for developing type 2 diabetes (hereafter called diabetes), which is defined by elevated glycemic values that are below the diagnostic threshold for diabetes. Ninety-eight million U.S. adults (38%) have …

Clustering of childhood acute leukemia in Finland: a nationwide register-based study

Acute leukemia is the most common malignancy in children, yet its etiology remains largely unknown. Several somatic changes are required for the development of leukemia, and according to a prevailing hypothesis, the first often occurs during fetal …

Severe hypoglycaemia is associated with increased risk of adverse cardiovascular complications in adults with type 1 diabetes: risk mitigation using intermittently scanned continuous glucose monitoring

Despite advances in glycaemic management, people with type 1 diabetes remain at higher risk of CVD and CVD-related mortality than people without diabetes [ 1 ]. Data from the Swedish National Diabetes Register (NDR) reveal that people with type 1 …

Related topics

Disordered sleep and painful diabetic neuropathy

Pain symptoms from PDN can disrupt sleep, and disordered sleep can exacerbate pain. Learn about promising treatments for disordered sleep in people with PDN and the efficacy of treatments in improving pain and/or sleep quality.

Read more

Disordered sleep and painful diabetic neuropathy

Pain symptoms from PDN can disrupt sleep, and disordered sleep can exacerbate pain. Learn about promising treatments for disordered sleep in people with PDN and the efficacy of treatments in improving pain and/or sleep quality.

Read more

Focus on insulin icodec

A thorough overview of the safety and efficacy of once-weekly basal insulin icodec in type 1 and 2 diabetes, covering pharmacology, pharmacokinetics, adverse effects, drug interactions, and dose recommendations.

Read more