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Open Access Community-Acquired Pneumonia Case Study

A challenging case of CAP

A woman presenting with community-acquired pneumonia developed several serious complications, likely due to co-existence of poorly controlled diabetes and a late diagnosis of thyroid cancer.

Diabesity, stress, and cancer risk

Open Access Diabetes Review

Explore the relationship between emotional wellbeing, metabolic health, and the risk of developing cancer. Learn how stress may worsen the increased cancer risk in people with diabetes, obesity, or both.

Overlooked effect of angiotensin receptor–neprilysin inhibitor

Free for a limited time Medical Side Effect Case Study

Caution is needed when assessing insulin secretion capability and nephropathy in patients with diabetes who are being treated with an angiotensin receptor–neprilysin inhibitor.

Cardiorenal benefits of semaglutide in type 2 diabetes with CKD

05-06-2024 Type 2 Diabetes News

Semaglutide has renal and cardioprotective effects in people with type 2 diabetes and chronic kidney disease who are at high risk for complications. 

Measuring ketone bodies

Free for a limited time Ketoacidosis Review

Measurement of ketones is encouraged to aid the diagnosis and assessment of diabetic ketoacidosis, but which method should be used: urine analysis, blood testing, or measurement of breath acetone?

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Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

A challenging case of CAP

Open Access Community-Acquired Pneumonia Case Study

A woman presenting with community-acquired pneumonia developed several serious complications, likely due to co-existence of poorly controlled diabetes and a late diagnosis of thyroid cancer.

Overlooked effect of angiotensin receptor–neprilysin inhibitor

Free for a limited time Medical Side Effect Case Study

Caution is needed when assessing insulin secretion capability and nephropathy in patients with diabetes who are being treated with an angiotensin receptor–neprilysin inhibitor.

DPP4 inhibitors a cause of IgG4-related kidney disease?

Free for a limited time Interstitial Nephritis Case Study

A man with type 2 diabetes and IgG4-related kidney disease developed bullous pemphigoid. DPP4 inhibitor treatment, which also correlated with changes in renal function, was discontinued.

Using CGM to optimize type 2 diabetes management with non-intensive insulin treatment in primary care

With the growing importance of primary care in diabetes, this podcast discusses the evidence on continuous glucose monitoring (CGM) use, the role of primary healthcare, and practical tips for interpreting the ambulatory glucose profile (AGP) report. 

Supported by: Abbott Diabetes Care

Prof. Samuel Seidu
Developed by: Adis

Current Reviews

Importance of unfolded protein response modulation on diabetes management: a systematic review

Insulins Review article

The endoplasmic reticulum (ER) play a critical role in folding, assembling, and transporting new-synthesized proteins to their purposed locations [ 1 ]. Protein secretion beyond the ER capacity is one of the causes of the ER stress (ERS) leads to …

The role of IGF/IGF-1R signaling in the regulation of cancer stem cells

Insulins Review Article

Cancer stem cells (CSCs) are a group of tumor cells with high tumorigenic ability and self-renewal potential similar to those of normal stem cells. CSCs are the key “seeds” for tumor development, metastasis, and recurrence. A better insight into …

Diabetic neuropathy: understanding the nexus of diabetic neuropathy, gut dysbiosis and cognitive impairment

Diabetic Neuropathy Review article

Diabetes mellitus is a heterogeneous metabolic disorder characterised by elevated levels of blood glucose for a prolonged period. The broad classification of diabetes mellitus is Type 1 diabetes mellitus (TIDM) and Type 2 diabetes mellitus(T2DM).

Review Article – Diabetes Technology in the Hospital: An Update

Insulins REVIEW

Tight glycemic control is of paramount importance to prevent acute and chronic complications in both type 1 diabetes (T1D) [ 1 ] and type 2 diabetes (T2D) [ 2 ]. People with diabetes are at higher risk for hospitalization and complications due to …

Episode 10: Disease-modifying therapy for type 1 diabetes

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu
Insulins Clinical Trial Summary

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.

Developed by: Springer Medicine

Videos | Case Scenarios | Infographics (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)

Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Vodcasts | Case Scenarios (Link opens in a new window)

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Further Reading

BRG1 Deficiency Promotes Cardiomyocyte Inflammation and Apoptosis by Activating the cGAS-STING Signaling in Diabetic Cardiomyopathy

Open Access Diabetic Cardiomyopathy RESEARCH

Brahma-related gene 1 (BRG1) has been implicated in the repair of DNA double-strand breaks (DSBs). Downregulation of BRG1 impairs DSBs repair leading to accumulation of double-stranded DNA (dsDNA). Currently, the role of BRG1 in diabetic …

Development and psychometric evaluation of the type 1 diabetes mellitus self-management scale for parents

Open Access Type 1 Diabetes RESEARCH

Type 1 Diabetes Mellitus (T1DM) is a chronic disease that presents with high blood sugar resulting from insufficient secretion of insulin due to the destruction of beta cells in the pancreas. It requires long-term care and causes changes in the …

Healthy dietary pattern is associated with lower glycemia independently of the genetic risk of type 2 diabetes: a cross-sectional study in Finnish men

Open Access Type 2 Diabetes Original Contribution

Type 2 diabetes (T2D) is increasing globally and is one of the leading causes of morbidity and mortality in the world [ 1 ]. It is preceded by worsening glycemia i.e. prediabetes, which itself is a health hazard [ 2 , 3 ]. Hyperglycemia …

Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans

Open Access Type 1 Diabetes Original Research

Autoimmune type 1 diabetes is characterised by the progressive loss of insulin-producing beta cell mass and, eventually, insufficient insulin to maintain blood glucose levels within normal ranges. This progressive loss of functional beta cells is …

Related topics

A challenging case of CAP

Open Access Community-Acquired Pneumonia Case Study

A woman presenting with community-acquired pneumonia developed several serious complications, likely due to co-existence of poorly controlled diabetes and a late diagnosis of thyroid cancer.

Read more

Measuring ketone bodies

Free for a limited time Ketoacidosis Review

Measurement of ketones is encouraged to aid the diagnosis and assessment of diabetic ketoacidosis, but which method should be used: urine analysis, blood testing, or measurement of breath acetone?

Read more