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Ulcerative Colitis 

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  1. 08-05-2024 | Ulcerative Colitis | Online First

    Ulcerative colitis and nephrotic syndrome: a two-sample Mendelian randomization study

    To investigate the potential causal relationship between ulcerative colitis and nephrotic syndrome. We obtained the whole-genome association study data of ulcerative colitis in the European population from the GWAS database. Relevant single …

  2. 02-05-2024 | Ulcerative Colitis | Online First

    Arginase 2 attenuates ulcerative colitis by antioxidant effects of spermidine

    Inflammatory bowel disease (IBD) is a chronic, idiopathic, inflammatory disease comprising ulcerative colitis (UC) and Crohn's disease (CD) [ 1 ]. The incidence of IBD exceeds 0.3%, and more than 5 million people are affected worldwide [ 2 ]. UC is …

  3. 04-05-2024 | Ulcerative Colitis | Online First

    Promising modality for severe ulcerative colitis: infliximab and plant-based diet as first-line (IPF) therapy

  4. Open Access 06-05-2024 | Ulcerative Colitis | Online First

    Fecal calprotectin and platelet count predict histologic disease activity in pediatric ulcerative colitis: results from a projection-predictive feature selection

    Especially for pediatric patients, proxies of mucosal inflammation are needed. The Pediatric Ulcerative Colitis Activity Index (PUCAI) has been established to predict clinical and endoscopic disease activity. However, histologic inflammation might …

  5. 29-04-2024 | Ulcerative Colitis | Online First

    Efficacy of upadacitinib in the achievement of clinical and endoscopic remission in hospitalized patients with ulcerative colitis

    Janus kinase (JAK) inhibitors have been developed and are clinically available for management of active UC patients although most studies have been conducted for the outpatients and few studies have demonstrated its efficacy in endoscopic and …

  6. Open Access 01-12-2024 | Ulcerative Colitis | OriginalPaper

    Blockade of PI3K/AKT signaling pathway by Astragaloside IV attenuates ulcerative colitis via improving the intestinal epithelial barrier

    Ulcerative colitis (UC) is a chronic non-specific inflammatory disease of the colorectum of unknown etiology, mostly located in the sigmoid colon and rectum, with lesions generally confined to the mucosal and submucosal layers. The occurrence of …

  7. 18-04-2024 | Autoimmune Pancreatitis | Online First

    A Response-able Diagnosis: Type 2 Autoimmune Pancreatitis in the Setting of Ulcerative Colitis

    A previously healthy 36-year-old male was evaluated in the emergency department with two weeks of left-sided abdominal pain and diarrhea. The pain radiated to his back and was associated with poor oral intake and a 25-pound weight loss. Bowel …

  8. 24-04-2024 | Ulcerative Colitis | Online First

    Exploring Pyroptosis-related Signature Genes and Potential Drugs in Ulcerative Colitis by Transcriptome Data and Animal Experimental Validation

    Ulcerative colitis (UC) is an idiopathic, relapsing inflammatory disorder of the colonic mucosa. Pyroptosis contributes significantly to UC. However, the molecular mechanisms of UC remain unexplained. Herein, using transcriptome data and animal …

  9. Open Access 05-03-2024 | Ulcerative Colitis | OriginalPaper

    Patient experiences in ulcerative colitis: conceptual model and review of patient-reported outcome measures

    Patients with ulcerative colitis (UC) experience symptoms that can be disabling. New treatment options are needed for patients with UC. Patient-reported outcome (PRO) measures are questionnaires that ask patients about disease-related symptoms and …

  10. 20-02-2024 | Ulcerative Colitis | Erratum

    Correction to: Patchouli Alcohol: A Natural Sesquiterpene Against Both Inflammation and Intestinal Barrier Damage of Ulcerative Colitis

  11. Open Access 15-04-2024 | Ulcerative Colitis | Online First

    Real-World Treatment Patterns and Healthcare Resource Use for Ulcerative Colitis and Crohn’s Disease in Italy

    Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn’s disease (CD), both of which are chronic, relapsing and debilitating conditions with a disease course that may range in severity and progression [ 1 – 3 ]. In Italy, the …

  12. 15-02-2024 | Proctitis | OriginalPaper

    Effectiveness of Tofacitinib in Ulcerative Proctitis Compared to Left Sided Colitis and Pancolitis

    Ulcerative colitis (UC) is a chronic inflammatory bowel disease which can involve the colon to a variable extent i.e. may be limited to the rectum (proctitis), involve the left sided colon distal to splenic flexure (left sided colitis, LSC) or …

  13. 20-02-2024 | Ulcerative Colitis | Report

    Concurrent Arterial and Venous Thromboses in Ulcerative Colitis: A Complex Case of Multiorgan Involvement

  14. Open Access 19-03-2024 | Ulcerative Colitis | Letter

    Experience of Tofacitinib Use in Pregnancy in Patients with Ulcerative Colitis

  15. Open Access 01-12-2024 | Ulcerative Colitis | OriginalPaper

    Constituents of stable commensal microbiota imply diverse colonic epithelial cell reactivity in patients with ulcerative colitis

    Ulcerative colitis (UC) is a complex, chronic inflammatory disorder, characterized by periods of relapse and remission, often leading to significant morbidity and reduced quality of life [ 1 ]. While the exact etiology of UC remains elusive …

  16. Open Access 01-12-2024 | Ulcerative Colitis | OriginalPaper

    Short-chain fatty acid-producing bacterial strains attenuate experimental ulcerative colitis by promoting M2 macrophage polarization via JAK/STAT3/FOXO3 axis inactivation

    Inflammatory bowel disease (IBD) presents in two clinical forms—ulcerative colitis (UC) and Crohn’s disease (CD)—and is characterized by chronic relapsing and remitting inflammation in the gastrointestinal tract. IBD is associated with gut barrier …

  17. 05-04-2024 | Crohn's Disease | Online First

    Correlation Between Serum and Fecal Biomarkers and Patient-Reported Outcomes in Patients with Crohn’s Disease and Ulcerative Colitis

    Inflammatory bowel disease (IBD) comprising of Crohn’s disease (CD) and ulcerative colitis (UC) results in chronic inflammation of the gastrointestinal tract with a relapsing and remitting disease course [ 1 ]. Current assessment of disease …

  18. 08-04-2024 | Ulcerative Colitis | Online First

    Consistent efficacy outcomes between phase 2 and phase 3 trials in Crohn’s disease or ulcerative colitis in adults: a meta-analysis

    A vast number of people throughout the world suffer from inflammatory bowel disease (IBD), a chronic disorder marked by inflammation of the gastrointestinal system [ 1 ]. Two main types of IBD are Crohn’s disease (CD) and ulcerative colitis (UC) [ …

  19. 16-03-2024 | Ulcerative Colitis | Online First

    Resveratrol ameliorates DSS-induced ulcerative colitis by acting on mouse gut microbiota

    Ulcerative colitis (UC), which is mainly involved in the disruption of colon mucosal integrity and dysfunction of the barrier, is a chronic inflammatory disease (Duan et al. 2020 ). The incidence of UC is increasing all over the world and its …

  20. 21-11-2023 | Ulcerative Colitis | OriginalPaper

    Long Non-Coding RNA ANRIL Regulates Inflammatory Factor Expression in Ulcerative Colitis Via the miR-191-5p/SATB1 Axis

    Ulcerative colitis, an inflammatory bowel disease, manifests with symptoms such as abdominal pain, diarrhea, and mucopurulent feces. The long non-coding RNA (lncRNA) ANRIL exhibits significantly reduced expression in UC, yet its specific mechanism …

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