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Radiotherapy 

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  1. Open Access 01-12-2024 | Radiotherapy | EditorialNotes

    Advances in personalized radiotherapy

    Radiotherapy is a mainstay of cancer treatment. The clinical response to radiotherapy is heterogeneous, from a complete response to early progression. Recent studies have explored the importance of patient characteristics in response to …

  2. Open Access 01-12-2024 | Systemic Therapy | OriginalPaper

    The therapeutic effect of radiotherapy combined with systemic therapy compared to radiotherapy alone in patients with simple brain metastasis after first-line treatment of limited-stage small cell lung cancer: a retrospective study

    Small cell lung cancer (SCLC) is a highly aggressive malignant tumor, accounting for approximately 15% of all lung cancers [ 1 ]. Although most SCLC patients have high sensitivity to initial chemotherapy (CT) and radiotherapy (RT), most patients …

  3. Open Access 01-12-2024 | Metastasis | OriginalPaper

    FLASH radiotherapy for the treatment of symptomatic bone metastases in the thorax (FAST-02): protocol for a prospective study of a novel radiotherapy approach

    FLASH therapy is an emerging form of radiation therapy (RT) in which radiation is delivered at ultra-high dose rates of at least 40 Gy/s. Compared to RT given at conventional dose rates, FLASH RT has been shown in multiple animal models to cause …

  4. Open Access 30-04-2024 | Hepatocellular Carcinoma | Online First

    Managing hepatocellular carcinoma across the stages: efficacy and outcomes of stereotactic body radiotherapy

    A retrospective study

    Liver cancer, ranking as the 6th most prevalent malignancy globally and standing as the third leading cause of cancer-related death, is a challenging malignancy and is surpassed only by lung and colorectal cancer [ 1 ]. Hepatocellular carcinoma …

  5. 08-04-2024 | Radiotherapy | Erratum

    Correction: Tumor progression in tympanojugular paragangliomas: the role of radiotherapy and wait and scan

  6. Open Access 01-12-2024 | Radiotherapy | OriginalPaper

    PErspective and current status of Radiotherapy Service in IRan (PERSIR)-1 study: assessment of current external beam radiotherapy facilities, staff and techniques compared to the international guidelines

    The number of new cancer cases was 19.3 million people worldwide in 2020, which is expected to reach 24.6 million in 2030, suggesting an increase of 27.5% [ 1 ]. Developing countries account for around 60% of all new cancer cases and 70% of all …

  7. Open Access 15-03-2024 | Brachytherapy | Online First

    Radiotherapy in localized prostate cancer: a multicenter analysis evaluating tumor control and late toxicity after brachytherapy and external beam radiotherapy in 1293 patients

    Prostate cancer is an age-related disease [ 1 ]. Being the most common cancer in men [ 1 ] in an aging society, more cases are to be expected and more resources for treatment are required. For localized prostate cancer, 3 different options for …

  8. Open Access 01-12-2024 | Hepatocellular Carcinoma | OriginalPaper

    Prognostic analysis of radiation-induced liver damage following carbon-ion radiotherapy for hepatocellular carcinoma

    External beam radiotherapy (EBRT) and stereotactic body radiotherapy (SBRT) are viable treatment options for patients with unresectable or inoperable hepatocellular carcinoma (HCC) [ 1 ]. Current guidelines suggest that SBRT is an advanced EBRT …

  9. Open Access 01-12-2024 | Erratum

    Correction to: Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer

  10. Open Access 20-03-2024 | Breast Cancer | OriginalPaper

    Omission of adjuvant radiotherapy in low-risk elderly males with breast cancer

    Breast cancer in men is a rare age-related disease making up 1% of all breast cancers [ 1 ]. Although the lifetime risk of breast cancer is 1:1000 for a man compared to 1:8 for a woman, both sexes share overlapping risk factors leading to …

  11. 09-04-2024 | Tinnitus | Letter

    Reply to “comments on tumor progression in tympanojugular paragangliomas: the role of radiotherapy and wait and scan”

  12. Open Access 01-05-2024 | Radiotherapy | OriginalPaper

    Effect of radiotherapy on the surface roughness and microhardness of contemporary bioactive restorative materials

    Tooth caries ranks among the most prevalent chronic ailments affecting people worldwide. This condition can affect individuals throughout their lives. While the primary cause is the intricate interplay of factors like oral hygiene, nutrition, and …

  13. Open Access 01-12-2024 | Radiotherapy | OriginalPaper

    Anti-PD-1 antibody in combination with radiotherapy as first-line therapy for unresectable intrahepatic cholangiocarcinoma

    Cholangiocarcinoma (CCA) is the second most common hepatic malignancy, and the incidence and mortality rates of CCA, especially the intrahepatic cholangiocarcinoma (iCCA) has increased over the last 10-20 years [ 1 – 3 ]. Surgery remains the …

  14. Open Access 05-05-2024 | Radiotherapy | Online First

    Simultaneous integrated boost intensity-modulated radiotherapy post breast-conserving surgery: clinical efficacy, adverse effects, and cosmetic outcomes in breast cancer patients

    Breast cancer has become the most prevalent cancer among women, accounting for 11.7% of all global cancer cases [ 1 ]. This increase emphasizes the necessity for effective and efficient treatment strategies. The evolution of diagnostic and …

  15. Open Access 01-12-2024 | Radiotherapy | OriginalPaper

    REPeated mAgnetic resonance Image-guided stereotactic body Radiotherapy (MRIg-reSBRT) for oligometastatic patients: REPAIR, a mono-institutional retrospective study

    The prognosis of oligometastatic disease (OMD) has improved in terms of overall survival (OS) and progression free survival (PFS) in recent years, mainly due to multi-integrated treatment approaches combining novel systemic and local therapies …

  16. 26-04-2024 | Online First

    ASO Visual Abstract: Adjuvant Chemotherapy with or Without Radiotherapy for Resected Pancreatic Cancer Following Multiagent Neoadjuvant Chemotherapy

  17. 19-03-2024 | Oropharyngeal Cancer | OriginalPaper

    Upfront surgery versus definitive radiotherapy: competing risk analyses for cancer-specific and noncancer mortality in oropharyngeal cancer

    Oropharyngeal cancer (OPC) arises from the epithelium of the oropharyngeal area, including tonsils, base of the tongue, soft palate, and posterior pharyngeal wall. Squamous cell carcinoma accounts for > 90% of OPCs [ 1 ]. Although tobacco smoking …

  18. Open Access 01-12-2024 | NSCLC | OriginalPaper

    Blocking the MIF-CD74 axis augments radiotherapy efficacy for brain metastasis in NSCLC via synergistically promoting microglia M1 polarization

    Lung cancer is one of the most common cancers and a prime cause of cancer-related deaths worldwide [ 1 ]. Brain metastases are present in 57% of lung cancer patients, with 20% of patients presenting with brain metastasis (BM) at initial diagnosis …

  19. Open Access 01-12-2024 | Radiotherapy | OriginalPaper

    CircCDYL2 bolsters radiotherapy resistance in nasopharyngeal carcinoma by promoting RAD51 translation initiation for enhanced homologous recombination repair

    Nasopharyngeal Carcinoma (NPC) is a malignant tumor originating from the nasopharyngeal epithelium [ 1 ]. Its incidence demonstrates distinct geographical variations, with Southeast Asia, South China, and North Africa being high-risk regions [ 2 …

  20. Open Access 28-02-2024 | Radiotherapy | Online First

    Re-irradiation spine stereotactic body radiotherapy following high-dose conventional radiotherapy for metastatic epidural spinal cord compression: a retrospective study

    Metastatic epidural spinal cord compression (MESCC) is a major concern but a clinical challenge for the management of advanced cancer patients, leading to significant morbidity, including pain, loss of neurologic function, and poor quality of …

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