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15018 search results for:

Cutaneous Squamous Cell Carcinoma 

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  1. Open Access 17-04-2024 | Salivary Gland Cancer | Online First

    Metastatic cutaneous squamous cell carcinoma accounts for nearly all squamous cell carcinomas of the parotid gland

    Primary squamous cell carcinoma of the parotid gland (pSCCP) has long been recognized as a separate entity and is included in the WHO classifications of salivary gland tumors. However, it is widely accepted among head and neck pathologists that …

  2. Open Access 01-07-2024 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    Long-term survival after anti-PD-1 discontinuation in advanced cutaneous squamous cell carcinoma (cSCC): a proof of concept of benefit of concomitant cemiplimab and radiotherapy

    Advanced cutaneous squamous cell carcinomas (locally advanced and metastatic cSCC) are infrequent and have a worse prognosis than common primary cSCC. For those who are not candidates for curative surgery or radiotherapy, treatment with anti-PD-1 …

  3. 01-07-2024 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    Sentinel lymph node biopsy versus observation in high risk cutaneous squamous cell carcinoma of head and neck: a propensity score matching analysis

    Sentinel lymph node biopsy (SLNB) has gained considerable attention in the management of head and neck cutaneous squamous cell carcinoma (HNcSCC). The aim of this study was to compare the oncologic outcomes between observation and SLNB in cN0 …

  4. Open Access 01-12-2024 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    Assessment of perineural spread in advanced cutaneous squamous cell carcinomas treated with immunotherapy

    Keratinocyte cancers, including cutaneous squamous cell carcinoma (CSCC), are the most common cancers in humans with 2–3 million occurrences per year worldwide. CSCC incidence has increased 310% between 1990 to 2017 and most frequently arises in …

  5. Open Access 01-12-2024 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma

    Cutaneous squamous cell carcinoma (cSCC) is the second most common skin tumor after basal cell carcinoma (excluding melanoma), accounting for 20-50% of skin tumors [ 1 ]. According to the statistics, approximately 200,000-400,000 new cases of cSCC …

  6. Open Access 01-03-2024 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    Improved survival over time with immunotherapy in locally advanced and metastatic cutaneous squamous cell carcinomas

    Skin carcinomas are the most common human cancers. Cutaneous squamous cell carcinoma (cSCC) is the second most common type after basal cell carcinoma, and its dissemination capacity causes significant morbidity, resulting in the majority of …

  7. Open Access 23-03-2024 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    Inconsistent Associations Between Risk Factor Profiles and Adjuvant Radiation Therapy (ART) Treatment in Patients with Cutaneous Squamous Cell Carcinoma and Utility of the 40-Gene Expression Profile to Refine ART Guidance

    National Comprehensive Cancer Network (NCCN) recommendations for follow-up surveillance of patients diagnosed with cutaneous squamous cell carcinoma (cSCC) are different but overlapping for the NCCN-defined Low Risk, High Risk, and Very High Risk …

  8. 12-04-2024 | Online First

    Quality of Life Assessment and Comparative Analysis of Anterolateral Thigh Flap and Pectoralis Major Myo-cutaneous Flap for Reconstruction of Post Excision Defects of Oral Squamous Cell Carcinoma

    Present study is a comparative evaluation of the financial impact on choice of flap, clinical results as well as post resection quality of life assessment of cancer patients reconstructed with anterolateral thigh(ALT) flap and pectoralis major …

  9. Open Access 06-03-2024 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    Real-World Experience of Immune-Checkpoint Inhibitors in Older Patients with Advanced Cutaneous Squamous Cell Carcinoma

    Cutaneous squamous cell carcinoma (CSCC) is one of the most common malignancies in Australia owing to high levels of ultraviolet-light (UV) exposure, an outdoors culture, and a large Caucasian population [ 1 ]. CSCC is reported to account for …

  10. Open Access 01-03-2024 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    Integrating the 40-Gene Expression Profile (40-GEP) Test Improves Metastatic Risk-Stratification Within Clinically Relevant Subgroups of High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) Patients

    Of the 1.8 million people in the US diagnosed with cutaneous squamous cell carcinoma (cSCC) each year [ 1 – 3 ], approximately 5–8% develop regional or distant metastasis, with annual mortality estimated to be higher than that for melanoma [ 4 – 6 …

  11. 01-01-2024 | Cutaneous Squamous Cell Carcinoma | Letter

    Survival analyses in cutaneous squamous cell carcinoma: accounting for both competing risks and repeated measures

  12. 26-10-2023 | Cutaneous Squamous Cell Carcinoma | News | Article
    ESMO 2023

    Neoadjuvant cemiplimab in cutaneous squamous cell carcinoma

    A recent phase II study shows encouraging results for the neoadjuvant treatment of cutaneous squamous cell carcinoma with the PD-1 inhibitor cemiplimab.

  13. Open Access 01-12-2023 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    Competing-risks analysis for evaluating the prognosis of patients with microinvasive cutaneous squamous cell carcinoma based on the SEER database

    Cutaneous squamous cell carcinoma (cSCC) is the second most common type of nonmelanoma skin cancer behind basal cell carcinoma [ 1 ]. It accounts for 20% of all skin cancers, with 1 million cases diagnosed each year in the United States and an …

  14. 24-10-2023 | Cutaneous Squamous Cell Carcinoma | Erratum

    Retraction Note: Long non-coding RNA PICSAR serves as a non-invasive biomarker for the diagnosis and prognosis of cutaneous squamous cell carcinoma

  15. Open Access 09-11-2023 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    Health-Related Quality of Life with Pembrolizumab in Patients with Locally Advanced or Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma: KEYNOTE-629

    Cutaneous squamous cell carcinoma (cSCC) is a common type of nonmelanoma skin cancer (NMSC) resulting from uncontrolled proliferation of epidermal keratinocytes [ 1 , 2 ]. While traditionally considered to account for 20% of cutaneous malignancies …

  16. Open Access 01-12-2023 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    Successful management of in-transit cutaneous squamous cell carcinoma with anti-PD-1 immunotherapy

    This report describes the case of a 70-year-old man with metastatic squamous cell carcinoma (SCC) of the right lower leg. Soon after definitive surgical management of the primary and nodal metastases with curative intent, he relapsed, developing …

  17. 09-08-2023 | Voriconazole | OriginalPaper

    Posaconazole and risk of cutaneous squamous cell carcinoma after lung transplantation: a single institution, retrospective cohort study

    The use of voriconazole as an antifungal prophylaxis after lung transplantation has shown positive outcomes [ 1 ]. However, it is also associated with an increased risk of post-transplant cutaneous squamous cell carcinoma (SCC). Posaconazole has …

  18. Open Access 01-12-2022 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    From Bowen disease to cutaneous squamous cell carcinoma: eight markers were verified from transcriptomic and proteomic analyses

    Cutaneous squamous cell carcinoma (CSCC) is one of the most common cutaneous carcinoma in the elderly. With the extension of life expectancy in human, the prevalence of CSCC keeps rasing, with an annual global incidence more than 1 million [ 1 ].

  19. Open Access 01-12-2022 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    A nomogram combining clinical factors and biomarkers for predicting the recurrence of high-risk cutaneous squamous cell carcinoma

    Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, and its incidence is increasing annually [ 1 , 2 ]. Complete surgical excision is the treatment of choice for cSCC, and further systemic treatment is not required for …

  20. 05-07-2023 | Cutaneous Squamous Cell Carcinoma | OriginalPaper

    CircIFFO1 suppresses tumor growth and metastasis of cutaneous squamous cell carcinoma by targeting the miR-424-5p/NFIB axis

    Cutaneous squamous cell carcinoma (CSCC) is a severe malignancy derived from the skin. Circular RNAs (circRNAs) play an important role in the pathological process of many malignant tumors. Moreover, circIFFO1 is reported to be down-regulated in …

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