Skip to main content

Appendectomy better at preventing ulcerative colitis relapse

Appendectomy plus maintenance medical therapy is better than standard medical therapy alone in maintaining remission in patients with ulcerative colitis, the ACCURE study reports.

Read more

Editor's Choice

The evolving treatment landscape of advanced prostate cancer

The advent of PSMA-targeted radioligand therapies and bispecific T-cell engagers has provided new hope for patients with metastatic castration-resistant prostate cancer. Explore the latest evidence.

Long-term benefits for islet transplantation in type 1 diabetes

Islet transplantation alone significantly reduces the long-term risk for death and islet-after-kidney transplantation significantly reduces the long-term risk for dialysis in people with type 1 diabetes.

Angiography-derived FFR comparable to IV ultrasound for guiding PCI

Angiography-derived fractional flow reserve is noninferior to intravascular ultrasound imaging for guiding PCI in patients with suspected CAD.

IL-17A inhibition in rheumatic and musculoskeletal diseases

Targeting the IL-17 pathway has already transformed the management of psoriatic arthritis and axial spondyloarthritis, and now IL-17A inhibitors are being explored in giant cell arteritis and polymyalgia rheumatica.

Our tailored content service will keep you up to date…

Receive newsletters curated for the busy specialist by our expert editorial team

Keynote series | Spotlight on managing health in obesity

Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.

Prof. Eva L. Feldman
Prof. Jonette Keri
Developed by: Springer Medicine
Watch now
Video

How can you integrate PET into your practice? (Link opens in a new window)

PET imaging is playing an increasingly critical role in managing AD. Our expert-led program will empower you with practical strategies and real-world case studies to effectively integrate it into clinical practice.

This content is intended for healthcare professionals outside of the UK.

Supported by:
  • Lilly
Developed by: Springer Healthcare IME
Register your interest

Case Studies

Novel association of chilblains with inflammatory arthritis

  • Free for a limited time
  • Arthritis
  • Case Study

Three patients with inflammatory arthritis had concomitant chilblains and bone marrow edema as revealed by MRI. Could this trifecta represent a new clinical phenotype of seronegative spondyloarthropathies?

An unusual cause of gastric outlet obstruction in infancy

A 2-month-old girl presented with repeated projectile nonbilious vomiting. What was the cause of her hugely dilated stomach, prepyloric stricture, and delayed gastric emptying?

Benign vs sinister causes of basal cistern subarachnoid hemorrhage

These six cases demonstrate a variety of causes for SAH in the basal cisterns, highlighting the contrasting clinical and imaging features, how to investigate when they are suspected, and significant differences in management.

Keynote webinar | Spotlight on advances in lupus

  • Live
  • Webinar | 27-05-2025 | 18:00 (CEST)

Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Join this session to learn more about novel biomarkers for diagnosis and monitoring and familiarise yourself with current and emerging targeted therapies.

Join us live: Tuesday 27th May, 18:00-19:15 (CEST)

Prof. Edward Vital
Prof. Ronald F. van Vollenhoven
Developed by: Springer Medicine
Register now
Webinar

Episode 18: The fight for children's eyesight

What can we do to reduce mounting myopia prevalence?

Global prevalence of myopia in children and adolescents is set to reach 40% by 2050, exceeding 740 million cases.

Reducing incidence and slowing progression is essential, as myopia is linked to sight-threatening complications like retinal detachment, myopic macular degeneration, and glaucoma. Dr. Annegret Dahlmann-Noor explores the reasons behind this increase and what we can do to halt the trend.

Dr. Annegret Dahlmann-Noor
Listen now
Podcast

CME & eLearning

Webinar

In this interactive webinar, experts discuss best pathological practices within NSCLC and thyroid cancer, as well as how genomic testing can improve outcomes in clinical practice, using patient case studies as illustrations. 

This content is intended only for US-based healthcare providers.

Supported by:
  • Illumina, Inc., and Eli Lilly and Company
Developed by: Springer Healthcare

Expert Interviews (Link opens in a new window)

PET imaging is playing an increasingly critical role in early diagnosis of AD, disease staging, and guiding treatment decisions. But how can you effectively integrate it into clinical practice? Our expert-led program will empower you with practical strategies and real-world case studies.

This content is intended for healthcare professionals outside of the UK.

Supported by:
  • Lilly
Developed by: Springer Healthcare IME

eLearning (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME

Keynote series | Spotlight on menopause

Menopause can have a significant impact on the body, with effects ranging beyond the endocrine and reproductive systems. Learn about the systemic effects of menopause, so you can help patients in your clinics through the transition.   

Prof. Martha Hickey
Dr. Claudia Barth
Dr. Samar El Khoudary
Developed by: Springer Medicine
Watch now
Video

Further Reading

Testosterone Therapy in Older Men: Present and Future Considerations

Testosterone is the classical male anabolic hormone, involved in sexual development, virilisation and regulation of body composition in adult men. Organic disease involving the hypothalamus, pituitary or testes may interfere with endogenous …

Effects of the ABC pathway on clinical outcomes in very elderly Chinese patients with atrial fibrillation. A report from the optimal thromboprophylaxis in elderly Chinese patients with atrial fibrillation (ChiOTEAF) registry

The current Atrial fibrillation Better Care (ABC) pathway for holistic or integrated management of AF is associated with improved clinical outcomes; however, data on the very elderly (aged ≥ 85 years) are sparse.To evaluate the impact of ABC …

Combined endoscopic-percutaneous approach for magnetic compression anastomosis in post-transplant anastomotic biliary strictures

Liver transplantation is a life-saving procedure for patients with end-stage liver disease, acute liver failure, and primary liver cancer [ 1 , 2 ]. Biliary complications account for the majority of morbidity and mortality following liver …

The Nutmeg Lung Pattern in a Fetus with Hypoplastic Left Heart Syndrome and Turner Syndrome

The “nutmeg lung pattern” on fetal magnetic resonance imaging (MRI) indicates pulmonary lymphangiectasia. This is associated with adverse outcomes, particularly in fetuses with congenital heart defects and impaired pulmonary venous return. Whereas …

Incorporating comprehensive genomic profiling into the standard-of-care for NSCLC and thyroid cancer

In this interactive webinar, experts Dr. Subbiah, Dr. Drilon, and Dr. Williams discuss best pathological practices within NSCLC and thyroid cancer, as well as how genomic testing can improve outcomes in clinical practice, using patient case studies as illustrations.

This content is intended only for US-based healthcare providers.

Supported by:
  • Illumina, Inc., and Eli Lilly and Company
Dr. Vivek Subbiah
Dr. Alexander Drilon
Dr. Michelle Williams
Developed by: Springer Healthcare
Watch now
Video

Episode 17: Challenges of developing DMOADs

Why are disease-modifying treatments for osteoarthritis such a difficult proposition?

Despite multiple attempts, no DMOAD is yet approved for clinical use. Prof. Ali Mobasheri takes us through the main challenges, the work being done to make these so-called utopia drugs a reality, and discusses other advances that offer hope in the meantime.

Prof. Ali Mobasheri
Listen now
Podcast

On-demand keynote webinars

Keynote webinar | Spotlight on modern management of frailty

Frailty has a significant impact on health and wellbeing, especially in older adults. Our experts explain the factors that contribute to the development of frailty and how you can manage the condition and reduce the risk of disability, dependency, and mortality in your patients.

Video

Keynote webinar | Spotlight on medication adherence

  • On-demand Webinar

Our experts explain the fundamentals of non-adherence, with a practical discussion of how to manage non-adherence in two common scenarios: hypertension and asthma control.

Video

Keynote webinar | Spotlight on sleep in brain health

  • On-demand Webinar

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.

Video

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

  • On-demand Webinar

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Video

Keynote webinar | Spotlight on diet and diabetes

  • On-demand Webinar

Uncertainty remains about the optimal dietary approaches to diabetes prevention and management, and how best to support patients. Recent EASD dietary guidelines underpin this discussion on weight management, including use of therapeutic diets, food types and processing, plus the psychological factors that influence patient success.

Video

Keynote webinar | Spotlight on cardio-oncology

  • On-demand Webinar

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Current Reviews

Potential Mechanisms for Immunotherapy Resistance in Adult Soft-Tissue Sarcoma

Soft-tissue sarcomas represent a diverse group of rare malignancies originating from mesenchymal tissue, accounting for less than 1% of adult cancers in the USA. With over 13,000 new cases and around 5350 deaths annually, patients with metastatic …

Emerging treatment approaches for VEXAS syndrome: a systematic review and meta-analysis

VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a monogenic autoinflammatory disorder with significant morbidity and mortality. Numerous treatment options including azacitidine, JAK inhibitors, IL-6 inhibitors …

Detection rates for prostate cancer using PI-RADS 2.1 upgrading rules in transition zone lesions align with risk assessment categories: a systematic review and meta-analysis

Magnetic resonance imaging (MRI) has become a widely utilized tool for the detection and risk stratification of prostate cancer (PCa). The Prostate Imaging Reporting and Data System version 2.1 (PI-RADS v2.1) has been established as a risk …

The Landmark Series: Organ Preservation in Rectal Cancer—The Watch and Wait Strategy

Radical treatment of rectal cancer has evolved quite significantly over the last few decades with the development of optimal local disease staging with magnetic resonance (MR), refined surgical techniques including total mesorectal excision (TME) …

Related topics

Long-term outcomes after giant cavernous sinus hemangioma

Cavernous sinus hemangiomas are rare vascular tumors characterized by significant intraoperative bleeding which makes management extremely difficult. This case reports the 15 year follow up, without neurological compromise, after successful ligation of the left internal carotid artery during resection. 

Read more

Long-term benefits for islet transplantation in type 1 diabetes

Islet transplantation alone significantly reduces the long-term risk for death and islet-after-kidney transplantation significantly reduces the long-term risk for dialysis in people with type 1 diabetes.

Read more

Long-term benefits for islet transplantation in type 1 diabetes

Islet transplantation alone significantly reduces the long-term risk for death and islet-after-kidney transplantation significantly reduces the long-term risk for dialysis in people with type 1 diabetes.

Read more

Non-celiac enteropathies

Identifying the cause of non-celiac enteropathy can be difficult, with common etiologies including immunodeficiency, infection, medication, and malignancy. Early nutrition support may minimize morbidity.

Read more

Disease-modifying therapies in lupus nephritis

Of the current treatments for lupus nephritis, how many can be classed as disease modifying according to recently proposed criteria? And what are the challenges and considerations for future studies?

Read more

Disordered sleep and painful diabetic neuropathy

Pain symptoms from PDN can disrupt sleep, and disordered sleep can exacerbate pain. Learn about promising treatments for disordered sleep in people with PDN and the efficacy of treatments in improving pain and/or sleep quality.

Read more

IL-17A inhibition in rheumatic and musculoskeletal diseases

Targeting the IL-17 pathway has already transformed the management of psoriatic arthritis and axial spondyloarthritis, and now IL-17A inhibitors are being explored in giant cell arteritis and polymyalgia rheumatica.

Read more