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25-04-2024 Pulmonary Hypertension News

MERIT-1 study continues to support macitentan for CTEPH

Macitentan significantly improves pulmonary vascular resistance in people with inoperable chronic thromboembolic pulmonary hypertension.

Pitfalls in the assessment of hypopituitarism

Open Access Hypopituitarism Review

Definitive diagnosis of pituitary insufficiency is largely based on laboratory tests, but these tests have limitations. Clinicians need to be alert to laboratory values that do not match the clinical picture.

Chronic stridor in a toddler caused by a discharged button battery

Ingested button batteries are usually charged and quickly cause severe symptoms, but ingesting a discharged battery is very rare. Unspecific symptoms can complicate and delay diagnosis, risking long-term complications.

Improving drug delivery in glioblastoma

Open Access Glioblastoma Review

Glioblastoma remains resistant to most conventional treatments. Emerging therapies aim to overcome the challenges posed by the blood–brain barrier and tumor microenvironment.

Fabry disease: the promise of personalized medicine

Open Access Fabry Disease Review

Learn about Fabry disease, a rare disease that can have renal, cardiovascular, neurological, cutaneous, and ophthalmic manifestations. Discover the ways in which it may be possible to personalize treatment.

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Live Webinar | 02-05-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on sleep in brain health

Live: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.

Dr. Rolf Fronczek
Dr. Sven Rupprecht
Dr. Renata Riha
Developed by: Springer Medicine

Chronic stridor in a toddler caused by a discharged button battery

Ingested button batteries are usually charged and quickly cause severe symptoms, but ingesting a discharged battery is very rare. Unspecific symptoms can complicate and delay diagnosis, risking long-term complications.

A CPR-induced subpleural hematoma

Open Access Hematoma Case Study

Development of a pulmonary hematoma in the subpleural area after bystander CPR. Surgical intervention was successful. 

Insulinoma misidentified as schizophrenia

Free for a limited time Insulinoma Case Study

Intermittently scanning CGM detected hypoglycemia in a woman previously diagnosed with schizophrenia and treated with antipsychotic medication. Insulinoma was diagnosed and resected, resolving her neuropsychiatric symptoms.

Live Webinar | 10-06-2024 | 16:30 (CEST)

Challenges in advanced CTCL – diagnosis and management

Live: Monday 10 June 2024, from 16:30 – 18:00 (CEST)

In this live interactive webinar, a multidisciplinary team of speakers will provide practical guidance on managing patients with cutaneous T-cell lymphoma. Learn about the key aspects of diagnosis and treatment via a series of patient cases.

Sponsored by: Kyowa Kirin

Developed by: Springer Healthcare

Current Reviews

Complications and visual outcomes following surgical resection of pediatric optic pathway/hypothalamic gliomas: a systematic review and meta-analysis

Glioma Review

Pediatric optic pathway/hypothalamic gliomas (OPHG) pose challenges in treatment due to their location and proximity to vital structures. Surgical resection plays a key role in the management of OPHG especially when the tumor exhibits mass effect …

Obesity and thyroid cancer: unraveling the connection through a systematic review and meta-analysis of cohort studies

Thyroid Cancer Review article

While thyroid cancer stands as the most common form of endocrine cancer, it is a comparatively uncommon malignancy, representing a mere 4% of global cancer cases according to GLOBOCAN 2018 statistics [ 1 ]. Furthermore, Asia is the region where 60% …

Sleep and Long COVID—A Review and Exploration of Sleep Disturbances in Post Acute Sequelae of SARS-COV-2 (PASC) and Therapeutic Possibilities

Post Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2), also known as PASC, also referred to as “long-haul COVID-19”, Post-COVID Syndrome, chronic COVID syndrome, long-COVID, or Post Acute Coronavirus Disease 2019 …

Current Progress, Challenges and Prospects in the Development of COVID-19 Vaccines

COVID-19 Vaccination Review Article

The COVID-19 pandemic has resulted in over 772 million confirmed cases, including nearly 7 million deaths, according to the World Health Organization (WHO). Leveraging rapid development, accelerated vaccine approval processes, and large-scale …

Alzheimer's Disease Independent Medical Education

Advances in Alzheimer's

Alzheimer's research and care is changing rapidly. Keep up with the latest developments from key international conferences, together with expert insights on how to integrate these advances into practice.

This content is intended for healthcare professionals outside of the UK.

Supported by: Lilly

Developed by: Springer Healthcare IME

Episode 10: Disease-modifying therapy for type 1 diabetes

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu

Springer Medicine webinars: on demand

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Webinar | 19-02-2024 | 17:30 (CET)

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Keynote webinar | Spotlight on diet and diabetes

Webinar | 08-11-2023 | 18:00 (CET)

An expert-led symposium exploring the prevention and management of type 2 diabetes through dietary interventions. Highlights include discussion of the recent EASD guidelines, therapeutic diets, food types and processing, plus psychological factors that influence patient success, and the drivers of healthy eating and diabetes control.

Keynote webinar | Spotlight on cardio-oncology

Webinar | 16-05-2023 | 17:30 (CEST)

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Webinar (Link opens in a new window)

1.25 AMA PRA Category 1 Credit(s)

A collaborative program highlighting the importance of molecular assessments and targeted treatment selection in people with biomarker-positive disease. Submit your questions for the experts now.

Supported by:
  • Roche and Illumina
Developed by: Springer Healthcare IME

Expert Interviews | Videos (Link opens in a new window)

With adolescent obesity at an all-time high, greater understanding of the individual cost and societal burden is crucial. Discover the unique challenges faced by adolescents with obesity, and learn effective strategies to help young people to overcome this disease.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Further Reading

Interactions between folate metabolism-related nutrients and polymorphisms on colorectal cancer risk: a case-control study in the Basque country

Open Access Colorectal Cancer Original Contribution

Folate-mediated one-carbon metabolism (FOCM) plays an important role in colorectal carcinogenesis. Previous studies have assessed the role of folate-mediated one-carbon metabolism (FOCM)-related gene-diet interaction in the aetiology of colorectal …

Radiographic findings in patients suspected of subacromial impingement syndrome: prevalence and reliability

Open Access Subacromiales Impingement Scientific Article

Subacromial impingement syndrome (SIS) or subacromial pain syndrome is a term used for a variety of shoulder disorders assumed to arise from subacromial pathologies [ 1 , 2 ]. From 2007 to 2011, around 60,000 working age patients were diagnosed …

Long-term recurrence of Dupuytren’s disease treated with clostridium histolitycum collagenase. Surgical treatment and anatomopathological study

Open Access Dupuytren Disease Orthopaedic Surgery

Dupuytren’s disease (DD) is a progressive fibroproliferative disorder characterized by the development of collagen nodules and cords at the superficial palmar aponeurosis level that causes progressive finger closure [ 1 ].

Predictors of significant distress in cervical cancer patients: a cross sectional study

Open Access Cervical Cancer Gynecologic Oncology

Cervical cancer is the fourth most common malignancy in women worldwide [ 1 ]. With the introduction of cervical cancer screening programs, a decrease in the incidence of cervical cancer since 1970 was achieved. Nonetheless 4575 women were newly …

Related topics

The delayed titration of guideline-directed drug therapy (GDMT) is complex and often results in poor prognosis for heart failure patients. Are you using GDMT in the most effective way?

Read more

Intermittently scanning CGM detected hypoglycemia in a woman previously diagnosed with schizophrenia and treated with antipsychotic medication. Insulinoma was diagnosed and resected, resolving her neuropsychiatric symptoms.

Read more

Definitive diagnosis of pituitary insufficiency is largely based on laboratory tests, but these tests have limitations. Clinicians need to be alert to laboratory values that do not match the clinical picture.

Read more

Intermittently scanning CGM detected hypoglycemia in a woman previously diagnosed with schizophrenia and treated with antipsychotic medication. Insulinoma was diagnosed and resected, resolving her neuropsychiatric symptoms.

Read more

Differentiating autoimmune pulmonary alveolar proteinosis (APAP) from a flare-up of interstitial pneumonia associated with dermatomyositis is challenging. This case highlights the need for early APAP scrutiny.

Read more