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Digital interventions and adherence in type 1 diabetes

Digital health interventions have gained prominence in the management of chronic diseases, but how do they impact clinical and patient-related outcomes and health behavior in people with type 1 diabetes?

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Editor's Choice

Obesity, pre-eclampsia, and diabetes increase liver disease risk in pregnancy

Obesity, pregestational diabetes, and pre-eclampsia increase the risk for steatosis and increased liver stiffness in the third trimester of pregnancy.

Rare forms of congenital adrenal hyperplasia

Update on the pathogenesis, clinical presentation, diagnosis, management, and treatment of rare forms of congenital adrenal hyperplasia, the most common cause of primary adrenal insufficiency in childhood.

Incretin-based therapies after bariatric surgery may protect against alcohol use disorder

Use of incretin-based therapies may reduce the risk for alcohol use disorder in people who undergo Roux-en-Y gastric bypass or sleeve gastrectomy.

CGM for the management and prevention of type 2 diabetes

Examine the evidence supporting the expanding role of CGM in type 2 diabetes, from active management of established disease to early identification of dysglycemia in individuals with prediabetes.

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Keynote webinar | Spotlight on the insulin toolkit for type 2 diabetes

  • Live
  • Webinar | 16-02-2026 | 18:00 (CET)

Insulin remains key to the management of type 2 diabetes, but its role continues to evolve with the arrival of once-weekly regimens presenting new opportunities and challenges. How can once-weekly insulin therapy be implemented to optimize patient care?

Watch it live: Monday 16 February 2026, 18:00-19:00 (CET)

Dr. Alice Cheng
Register now
Webinar

Raising the standard: ensuring patient safety through minimum requirements for CGM performance

Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.

Supported by:
  • Abbott Diabetes Care
Prof. Chantal Mathieu
Watch now
Video

Case Studies

Muscular dystrophy or congenital hypothyroidism?

Thyroxine replacement led to marked clinical improvement and regression of hypertrophy in a young man with symptoms mimicking muscular dystrophy but diagnosed with Kocher-Debré-Semelaigne/Hoffmann syndrome.

ICI-associated hypothyroidism, macular rash, and adrenal insufficiency

A complex case of hypothyroidism, macular rash, and adrenal insufficiency that developed in an older man several months after he received sintilimab for the treatment of esophageal carcinoma.

Effective treatment of pretibial myxedema with tofacitinib

A man with Graves disease and orbitopathy presented with bilateral pretibial myxedema. Oral tofacitinib was initiated after transient response to intralesional glucocorticoids‒edema and orbitopathy improved within 1 month.

Episode 24: Looking back at 2025

Advancing patient care

In this special edition of Medicine Matters, we're joined by Dr Gregory Lim, Claire Greenhill, and Sarah Onuora, Chief Editors of Nature Reviews Cardiology, Endocrinology, and Rheumatology, for a look back at the advances in their specialties in 2025.

Find out what caught their attention and why, and what they're looking forward to in 2026.

Gregory Lim
Claire Greenhill
Sarah Onuora
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Podcast

Current Reviews

Multimodal ultrasound assessment of ovarian reserve

Ovarian reserve represents the quantity and quality of a woman’s remaining oocytes and serves as a key indicator of reproductive potential. Accurate and non-invasive evaluation of ovarian reserve is essential for guiding fertility management …

ASCO 2025: key highlights in endometrial cancer

The 2025 ASCO Annual Meeting did not present immediately practice-changing results in endometrial cancer but showcased substantial progress across multiple therapeutic strategies. A phase II trial combining letrozole, abemaciclib, and metformin in …

Impact of probiotic, prebiotic, and synbiotic supplementation on the gut microbiome in older adults with sarcopenia, obesity, and sarcopenic obesity

Gut microbiome plays an important role in several metabolic, immune, and inflammatory pathways; however, there is limited evidence for its role in body composition and musculoskeletal health. Sarcopenia, defined as a loss of skeletal muscle mass …

PCSK9 and ANGPTL3 Inhibitors in Homozygous Familial Hypercholesterolemia: A Meta-analysis of Randomized Clinical Trials

Homozygous familial hypercholesterolemia (HoFH) is an autosomal semidominant disease characterized by markedly high levels of low-density lipoprotein cholesterol (LDL-C) leading to an increased risk for premature atherosclerotic cardiovascular …

Keynote webinar | Spotlight on addressing alcohol-associated liver disease

The global burden of ALD is growing and compounded by frequent late-stage diagnosis and undertreatment. Get the latest insights and advances in alcohol-associated liver disease, from patient risk and identification to treatment and management, plus the arrival of MetALD and what it means for patient care.

Prof. Helena Cortez-Pinto
Prof. Mark Thursz
Dr. Juan Pablo Arab
Learn more
Video

CME and eLearning

Integrating ketone and glucose monitoring for optimized diabetes management (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)

Familiarize yourself with current and emerging ketone monitoring systems and the most useful clinical scenarios in which to use them through our podcasts and e-learning modules. Lower the barriers to effective prevention of diabetic ketoacidosis.

Supported by:
  • Abbott
Developed by: Springer Health+ IME

Raising the standard: ensuring patient safety through minimum requirements for CGM performance

Prof. Chantal Mathieu highlights how the absence of rigorous performance standards for continuous glucose monitors in Europe contributes to wide variability in device accuracy, raising important concerns about patient safety.

Supported by:
  • Abbott Diabetes Care

Emerging biomarkers and comprehensive genomic profiling for NSCLC and thyroid cancer

  • NSCLC
  • On-demand Webinar

In this interactive webinar, experts discuss best pathological practices within NSCLC and thyroid cancer, as well as how genomic testing can improve outcomes in clinical practice, using patient case studies as illustrations. 

This content is intended only for US-based healthcare providers.

Supported by:
  • Illumina, Inc., and Eli Lilly and Company
Developed by: Springer Health+

Further Reading

Multimodal ultrasound assessment of ovarian reserve

Ovarian reserve represents the quantity and quality of a woman’s remaining oocytes and serves as a key indicator of reproductive potential. Accurate and non-invasive evaluation of ovarian reserve is essential for guiding fertility management …

Knowledge and practice of vitamin D supplementation in the German general population: results from a cross-sectional online survey

Vitamin D is a fat-soluble vitamin that plays an important role in bone metabolism (Holick 2007 ). In recent years, research has also focused on other, extra-skeletal effects of vitamin D. Observational studies have shown that low levels of …

Mortality and Causes of Death After Metabolic Bariatric Surgery in Older Patients

Obesity is a global health problem that currently affects 30–40% of adults in high-income countries [ 1 ]. Obesity is associated with several diseases, mainly diabetes, hypertension, cardiovascular diseases, cancer, and psychiatric disorders, as …

Epicardial Fat is Associated with Ventricular Dilation in Patients After the Fontan Operation

Epicardial and hepatic fat are suspected to play a role in cardiac remodeling. The primary objective of this study was to identify the cardiac MRI (CMR) parameters that are associated with indexed epicardial fat mass (EFMi) and hepatic steatosis …

Related topics

Rare forms of congenital adrenal hyperplasia

Update on the pathogenesis, clinical presentation, diagnosis, management, and treatment of rare forms of congenital adrenal hyperplasia, the most common cause of primary adrenal insufficiency in childhood.

Read more
Image Credits
Digital health concept image/© DSN_1 / stock.adobe.com, Woman at medical appointment/© Lacheev / iStock / Getty Images Plus, Model of adrenal gland and kidney/© Shidlovski / iStock / Getty Images Plus, Glasses of wine/© Giovanni Magdalinos / Getty Images / iStock, Woman checking CGM readings on a smartphone/© Javier Zayas Photography / Moment / Getty Images (symbolic image with model), Insulin injection needles / pens /© digicomphoto / iStock / Getty Images Plus, Statins in a blister pack/© Iryna Imago / Getty Images / iStock, Arrow pointing in the opposite direction/© tolgart / Getty Images / iStock, Close-up of a woman's face with hair above the upper lip/© Julia Cherkasova / iStock / Getty Images Plus (symbolic image with model), Man receiving injection/© InsideCreativeHouse / stock.adobe.com (symbolic image with models), Woman monitoring glucose level with sensor and an app on her phone while training at swimming pool/© (M) Goffkein, stock.adobe.com (symbolic image with model), Clinical images of hypertrophy/© (M) 2025, Subhajit Roy et al, Acta Neurol Belg, under exclusive licence to Belgian Neurological Society, ECG in a patient with hypothyroidism, macular rash, and adrenal crisis following ICI treatment/© 2025, Zhong-qing Mou et al, BMC Endocr Disord, Pretibial myxoedema before and after treatment with tofacitinib/© 2025, Chen-xi Zhao et al, Thyroid Res, Medicine Matters Podcast promo image/© Springer Medizin GmbH, Abstract low poly wireframe illustration of the liver/© (M) Yevhen Lahunov / iStock / Getty Images Plus, Integrating Ketone and Glucose Monitoring for Optimized Diabetes Management/© Springer Healthcare IME, Genetic code/© Springer Healthcare, Spirit level /© Martin Barraud / Stone / Getty Images, High blood pressure diagnostics concept/© sudok1 / Getty Images / iStock, 3D illustration of the pituitary gland/© Dr_Microbe / Stock.adobe.com, Resected left adrenal tumor/© (M) 2025, Shinnosuke Hata et al, BMC Endocr Disord, Arrowheads pointing down/© jayk7 / Moment/ Getty Images, 3D rendered human spermatozoa/© Vink Fan / stock.adobe.com, Bridge of books/© New Africa / stock.adobe.com, A scientist looking at a DNA sequence/© nicolas_ / Getty Images / iStock (symbolic image with models), Images of cryptorchidism in the inguinal region of a person with complete androgen insensitivity syndrome/© 2025, Kangji Liao et al, J Med Case Reports, Women's health concept image/© Kiattisak / Stock.adobe.com, Paradox image: walking in circles /© gremlin / getty, Doctor conducts a study on virtual screen/© Natali_Mis / iStock / Getty Images Plus, Being overlooked/overshadowed concept image/© Vlatko Gasparic / Moment / Getty Images, Question mark made of pills/© Nadzeya / stock.adobe.com, Ophthalmologist pointing to a model of eye anatomy/© Drazen Zigic / Getty Images / iStock (symbolic image with models), Imaging of ectopic lingual thyroid/© 2025, Pangmin Li et al, BMC Endocr Disord (CC-BY-NC-ND)