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Bruns–Garland syndrome as the initial manifestation of type 2 diabetes

Open Access Type 2 Diabetes Case Study

Diabetic radiculoplexus neuropathy, or Bruns–Garland syndrome, is a rare form of microvascular complication that more commonly affects the lumbosacral plexus and, very rarely, the cervical plexus.

Status of OCT angiography for diabetic retinopathy

Free for a limited time Diabetic Retinopathy Review

The applications of OCTA in diabetic retinopathy continue to grow. In particular, ultrawide field OCTA and AI based on OCTA images are making advances in terms of diagnostic accuracy.

Denosumab associated with lower risk for incident diabetes

28-02-2024 Type 2 Diabetes News

People with osteoporosis who continue with denosumab after their first dose are less likely to develop diabetes than those who discontinue therapy.

Update on menopausal HRT and type 2 diabetes

Open Access Type 2 Diabetes Review

Menopausal HRT may reduce the risk of type 2 diabetes developing and improve glycemic control. Individual risk factors must be considered when deciding a treatment plan.

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Bruns–Garland syndrome as the initial manifestation of type 2 diabetes

Open Access Type 2 Diabetes Case Study

Diabetic radiculoplexus neuropathy, or Bruns–Garland syndrome, is a rare form of microvascular complication that more commonly affects the lumbosacral plexus and, very rarely, the cervical plexus.

DVT: an unusual sign of pediatric scurvy

Open Access Metabolic Disease in Childhood Case Study

Signs of scurvy are non-specific and wide ranging, so vitamin C deficiency is often misdiagnosed. This is the first case of DVT caused by large pelvic subperiosteal hematomas in an autistic boy with severe dietary restriction.

HNF1A gene mutations and primary ovarian failure

Open Access Primary Ovarian Insufficiency Case Study

HNF1A mutations are responsible for maturity-onset diabetes of the young (MODY). Coexistence of POF and MODY 3 in an adolescent girl raised the idea that these mutations might also have a role in POF.

Current Reviews

Weight Gain in Midlife Women

Obesity Review

Midlife is the period of life between early adulthood and old age, typically between the ages of 40 and 65. This period is characterized by a variety of physical, psychological, and social changes, particularly in women as it coincides with the …

A review of type 3 Gaucher disease: unique neurological manifestations and advances in treatment

Gaucher Disease Review article

Gaucher disease (GD) is a rare lysosomal storage disease that is caused by mutations in the GBA gene. It is classified into three main phenotypes according to the patient’s clinical presentation. Of these, chronic neuronopathic GD (GD3) is …

Effects of Oral Iron Supplementation on Blood Iron Status in Athletes: A Systematic Review, Meta-Analysis and Meta-Regression of Randomized Controlled Trials

Open Access Iron Deficiency Systematic Review

The term ‘iron deficiency’ includes a plethora of physiological deficits induced by negative iron balance [ 1 ]. The early phase of iron deficiency is known as iron deficiency non-anaemia (IDNA) during which the haemoglobin concentration remains …

A systematic review of therapeutic enoxaparin dosing in obesity

Enoxaparin is a hydrophilic drug with obesity having little effect on its apparent volume of distribution, therefore patients with obesity receiving standard 1 mg/kg dosing may be at a higher risk of supratherapeutic dosing. Conversely, dose …

eLearning | Infographic (Link opens in a new window)

An independent educational program featuring simulated patient consultations. Make knowledge-based decisions on diagnosis and management of CKD with and without co-morbidities, and learn from experts Kevin Fernando and David Wheeler.

Supported by:
  • AstraZeneca
Developed by: Springer Healthcare IME

Webcast | Videos | Cases (Link opens in a new window)

Identifying molecular biomarkers is crucial in determining the best targeted treatment options for your patients with advanced thyroid cancer.

Join our expert-led multi-format educational program that explores the continuing discovery of new genomic targets and delivers the latest research in molecular testing and the application of targeted therapies for thyroid cancer.

Start by watching our webcast and short vodcasts.

Supported by:
  • Lilly
Developed by: Springer Healthcare IME

Webcast | Patient Cases (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)

Multiformat program improving awareness, diagnosis and management of patients with adult growth hormone deficiency.

Supported by:
  • Novo Nordisk Health Care AG
Developed by: Springer Healthcare IME

Further Reading

Trends in nutritional status and factors affecting prognostic nutritional index in ovarian cancer patients during chemotherapy: a prospective longitudinal study based on generalized estimating equations

Open Access Cytostatic Therapy Research

Ovarian cancer (OC) stands as one of the most prevalent gynecological malignancies, ranking as the fifth leading cause of cancer-related deaths among women in the USA [ 1 ]. Globally, 313,959 women were diagnosed, with 207,252 succumbing to OC in …

ACROMORFO study: gait analysis in a cohort of acromegalic patients

Open Access Acromegaly Original Article

Acromegaly is a rare disease characterized by growth hormone (GH) and insulin-like growth factor type I (IGF-I) hypersecretion, primarily due to somatotroph pituitary adenomas. Chronic exposure to high GH and IGF-I levels leads to the development …

Renal dysfunction caused by severe hypothyroidism diagnosed by renal biopsy: a case report

Open Access Hypothyroidism Case Report

There is a close relationship between thyroid dysfunction and renal dysfunction. However, thyroid dysfunction can unfortunately result in inaccurate measurements of serum creatinine and cystatin C levels. The chronic decrease in cardiac output due …

Preventing Stunting in South African Children Under 5: Evaluating the Combined Impacts of Maternal Characteristics and Low Socioeconomic Conditions

Open Access Malnutrition Original Research

More than 140 million children under five suffered from stunting in 2020. This highlights the ongoing challenge of addressing childhood malnutrition globally. We utilized data from a nationally representative sample of children under five years of …

Related topics

Open Access Primary Ovarian Insufficiency Case Study

HNF1A gene mutations and primary ovarian failure

HNF1A mutations are responsible for maturity-onset diabetes of the young (MODY). Coexistence of POF and MODY 3 in an adolescent girl raised the idea that these mutations might also have a role in POF.

Read more
Open Access Type 2 Diabetes Case Study

Bruns–Garland syndrome as the initial manifestation of type 2 diabetes

Diabetic radiculoplexus neuropathy, or Bruns–Garland syndrome, is a rare form of microvascular complication that more commonly affects the lumbosacral plexus and, very rarely, the cervical plexus.

Read more
Open Access Migraine Review

How do metabolic diseases affect migraine?

Migraine is associated with highly prevalent metabolic diseases, such as obesity, diabetes, and hypothyroidism. Understanding this relationship, and how metabolic diseases impact the efficacy of antimigraine drugs, is essential for optimal migraine treatment.

Read more