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Long-term benefits for islet transplantation in type 1 diabetes

Islet transplantation alone significantly reduces the long-term risk for death and islet-after-kidney transplantation significantly reduces the long-term risk for dialysis in people with type 1 diabetes.

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Editor's Choice

Disordered sleep and painful diabetic neuropathy

Pain symptoms from PDN can disrupt sleep, and disordered sleep can exacerbate pain. Learn about promising treatments for disordered sleep in people with PDN and the efficacy of treatments in improving pain and/or sleep quality.

Non-celiac enteropathies

Identifying the cause of non-celiac enteropathy can be difficult, with common etiologies including immunodeficiency, infection, medication, and malignancy. Early nutrition support may minimize morbidity.

YKL-40 linked to GI cancer risk in type 2 diabetes

Raised YKL-40 levels are associated with an increased risk for obesity-related and gastrointestinal cancers, particularly liver cancer, in people with type 2 diabetes.

Prolactinoma management: a complex path

This case highlights the challenges associated with managing an aggressive macroprolactinoma that's resistant to conventional treatments and explores the use of immunotherapy.

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Keynote series | Spotlight on managing health in obesity

Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.

Prof. Eva L. Feldman
Prof. Jonette Keri
Developed by: Springer Medicine
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Video

Incorporating comprehensive genomic profiling into the standard-of-care for NSCLC and thyroid cancer

In this interactive webinar, experts Dr. Subbiah, Dr. Drilon, and Dr. Williams discuss best pathological practices within NSCLC and thyroid cancer, as well as how genomic testing can improve outcomes in clinical practice, using patient case studies as illustrations.

This content is intended only for US-based healthcare providers.

Supported by:
  • Illumina, Inc., and Eli Lilly and Company
Dr. Vivek Subbiah
Dr. Alexander Drilon
Dr. Michelle Williams
Developed by: Springer Healthcare
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Video

Case Studies

Prolactinoma management: a complex path

This case highlights the challenges associated with managing an aggressive macroprolactinoma that's resistant to conventional treatments and explores the use of immunotherapy.

Skin infection or lymphoma in a woman with type 2 diabetes?

Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.

Colonic ischemia associated with a GLP-1 RA

Although it seems to be a rare complication, there should be a high index of suspicion for colonic ischemia in patients taking a GLP-1 receptor agonist who present with abdominal pain.

Keynote series | Spotlight on menopause

Menopause can have a significant impact on the body, with effects ranging beyond the endocrine and reproductive systems. Learn about the systemic effects of menopause, so you can help patients in your clinics through the transition.   

Prof. Martha Hickey
Dr. Claudia Barth
Dr. Samar El Khoudary
Developed by: Springer Medicine
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Video

Current Reviews

Vitamin B12 Deficiency in Children

Vitamin B12 deficiency poses significant health care challenges. Its deficiency is an important cause of nutritional anemia in children, next to iron deficiency. Though macrocytic/ megaloblastic anemia due to deficiency of vitamin B 12, is the …

Gastro-Oesophageal Reflux Disease Outcomes Following Roux-en-Y Gastric Bypass Surgery in Patients with Obesity: A Systematic Review and Meta-analysis

We aimed to investigate the effect of primary Roux-en-Y gastric bypass (RYGB) on gastro-oesophageal reflux disease (GORD) in patients with obesity. A systematic review was performed using MEDLINE, Embase, Emcare, and CINAHL databases for studies …

Advancing Cardiovascular, Kidney, and Metabolic Medicine: A Narrative Review of Insights and Innovations for the Future

Cardiovascular, kidney and metabolic (CKM) conditions are interrelated, significantly contributing to morbidity, mortality and healthcare burden. Despite therapeutic advances, traditional disease-specific approaches often fail to address their …

The Impact of Bias and Stigma on Patient Referral for Metabolic/Bariatric Surgery: An Algerian Experience

Obesity is a chronic disease causing a major public health challenge, particularly in Algeria, yet in patient referrals for metabolic/bariatric surgery (MBS), the most effective treatment remain low. This study aims to analyze the factors …

Episode 13: Advances in MASLD and MASH

Welcoming a new name and a new treatment

Metabolic dysfunction-associated liver disease is a significant healthcare concern and burden. Until recently there was no approved pharmacologic treatment for the more serious form of the disease, metabolic dysfunction-associated steatohepatitis. 

In this wide-ranging conversation, Prof. Vlad Ratziu explains the rationale behind the recently updated subclassification and nomenclature for steatotic liver disease, puts the therapeutic advance of resmetirom into context, and looks to the future for MASLD and MASH.

Prof. Vlad Ratziu
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Podcast

CME & eLearning

Webinar

In this interactive webinar, experts discuss best pathological practices within NSCLC and thyroid cancer, as well as how genomic testing can improve outcomes in clinical practice, using patient case studies as illustrations. 

This content is intended only for US-based healthcare providers.

Supported by:
  • Illumina, Inc., and Eli Lilly and Company
Developed by: Springer Healthcare

Webcast | eLearning (Link opens in a new window)

1.0 Interprofessional Continuing Education (IPCE) credit, 1.0 AAPA Category 1 CME credits

Advances in patient-centered care and treatment for cardiopulmonary dysfunction are helping to increase life expectancy in DMD. This program equips multidisciplinary teams, including pediatric neurologists, pediatricians, pulmonologists, cardiologists, and endocrinologists, with key knowledge and skills to enhance care throughout the patient journey.

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME

Videos | Case Scenarios | Infographics (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)

Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Further Reading

Testosterone Therapy in Older Men: Present and Future Considerations

Testosterone is the classical male anabolic hormone, involved in sexual development, virilisation and regulation of body composition in adult men. Organic disease involving the hypothalamus, pituitary or testes may interfere with endogenous …

The Nutmeg Lung Pattern in a Fetus with Hypoplastic Left Heart Syndrome and Turner Syndrome

The “nutmeg lung pattern” on fetal magnetic resonance imaging (MRI) indicates pulmonary lymphangiectasia. This is associated with adverse outcomes, particularly in fetuses with congenital heart defects and impaired pulmonary venous return. Whereas …

Differential Effects of Endocrine Therapy Type on Quality of Life in Older (≥70 Years) Women with Early-Stage Breast Cancer

The REQUITE group study ( www.requite.eu ) is a multicenter prospective study conducted across 26 countries in Europe and North America. 23 The study was designed to identify and validate predictive genetic markers that predict risk of late …

Evaluation of autoimmune and inflammatory markers in bilateral sudden hearing loss

Sudden Hearing Loss (SHL) is a sensorineural hearing loss that develops within 72 h, resulting in a loss greater than 30 dB across at least three consecutive frequencies [ 1 ]. SHL is considered an otologic emergency, with an incidence of 5–20 per …

Related topics

Adrenal cortex senescence: an aging-related pathology?

Adrenal cortex senescence is characterized by an altered output of adrenal cortical hormones, which may be implicated in adverse clinical outcomes, but should it be considered an aging-related pathology?

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Non-celiac enteropathies

Identifying the cause of non-celiac enteropathy can be difficult, with common etiologies including immunodeficiency, infection, medication, and malignancy. Early nutrition support may minimize morbidity.

Read more

Acromegaly and cancer

The incidence of secondary neoplasia in patients with acromegaly has increased in recent years. What are the risk factors for cancer in these patients, which cancers are most common, and how should screening be approached?

Read more