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Internal Medicine Infectious Disease

Infectious Disease

18-04-2024 Tuberculosis News

Shortened rifampicin regimen promising as a tuberculosis preventive treatment

A 2-month regimen of daily rifampicin at 20 mg/kg has a comparable safety profile to the standard 4-month regimen of 10 mg/kg, but an inexplicably lower completion rate.

Bacterial ventriculitis in a patient with severe periodontitis

Open Access Inflammatory Brain Disease Case Study

Poor dental health can lead to life-threatening CNS infections, even in a healthy individual. This is the first case of ventriculitis caused by an oral pathogen.

CAP misdiagnoses increase unnecessary antibiotic use

One in eight hospitalized patients, particularly those with dementia, are inappropriately diagnosed with community-acquired pneumonia.

Bacterial endocarditis caused by contact lens use

Open Access Endocarditis Case Study

A 17-year-old female presented with high fever, general fatigue, and dim eyesight. She had used colored contact lenses 3 weeks previously. Traumatic injury of the eye vessels led to systemic hematogenous infection and subsequent endocarditis. 

Viruses and hematologic malignancies

A thorough understanding of the relationship between viruses and hematologic cancers can help clinicians to deliver precise therapies and monitor potential complications.

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Bacterial ventriculitis in a patient with severe periodontitis

Open Access Inflammatory Brain Disease Case Study

Poor dental health can lead to life-threatening CNS infections, even in a healthy individual. This is the first case of ventriculitis caused by an oral pathogen.

Bacterial endocarditis caused by contact lens use

Open Access Endocarditis Case Study

A 17-year-old female presented with high fever, general fatigue, and dim eyesight. She had used colored contact lenses 3 weeks previously. Traumatic injury of the eye vessels led to systemic hematogenous infection and subsequent endocarditis. 

An uncommon presentation of CRC

Open Access Colorectal Cancer Case Study

Sciatica due to Streptococcus gallolyticus infection of the spinal epidural space led to a diagnosis of colorectal cancer in a person with none of the usual signs and symptoms.

Current Reviews

Family Planning Counseling for Women Living with HIV in Low- and Middle-Income Countries: A Systematic Review of the Impact on Contraceptive Uptake, Intention to Use Contraception and Pregnancy Incidence, 2011 to 2022

Open Access Human Immunodeficiency Virus Substantive Review

Women’s ability to control their fertility and have the number of children they want when they want them is an internationally recognized human right. This right has been the driving force behind family planning programs in low- and middle-income …

Perforated Appendicitis in Children: Management, Microbiology, and Antibiotic Stewardship

Although appendicitis has been described for more than 300 years, its optimal management remains a topic of active investigation. Acute appendicitis is the most common cause of peritonitis in children, and rates of perforated appendicitis are much …

Sleep and Long COVID—A Review and Exploration of Sleep Disturbances in Post Acute Sequelae of SARS-COV-2 (PASC) and Therapeutic Possibilities

Post Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2), also known as PASC, also referred to as “long-haul COVID-19”, Post-COVID Syndrome, chronic COVID syndrome, long-COVID, or Post Acute Coronavirus Disease 2019 …

Current Progress, Challenges and Prospects in the Development of COVID-19 Vaccines

COVID-19 Vaccination Review Article

The COVID-19 pandemic has resulted in over 772 million confirmed cases, including nearly 7 million deaths, according to the World Health Organization (WHO). Leveraging rapid development, accelerated vaccine approval processes, and large-scale …

Further Reading

Modelling COVID-19 Vaccination in the UK: Impact of the Autumn 2022 and Spring 2023 Booster Campaigns

Open Access Vaccination Original Research

Current evidence suggests that the rapid development and implementation of the COVID-19 vaccination program in the UK in December 2020 achieved a substantial reduction in the number of clinically significant cases [ 1 ], the number of serious …

Clinical-based phenotypes in children with pediatric post-COVID-19 condition

Open Access Post-COVID Syndrome Original Article

In March 2020, the World Health Organization (WHO) declared the coronavirus disease 2019 (COVID-19) outbreak a global pandemic [ 1 ], affecting millions of people worldwide. COVID-19 is caused by severe acute respiratory syndrome coronavirus-2 …

Family Planning Counseling for Women Living with HIV in Low- and Middle-Income Countries: A Systematic Review of the Impact on Contraceptive Uptake, Intention to Use Contraception and Pregnancy Incidence, 2011 to 2022

Open Access Human Immunodeficiency Virus Substantive Review

Women’s ability to control their fertility and have the number of children they want when they want them is an internationally recognized human right. This right has been the driving force behind family planning programs in low- and middle-income …

The Impact of Telemedicine on Human Immunodeficiency Virus (HIV)-Related Clinical Outcomes During the COVID-19 Pandemic

Open Access Telemedicine Original Paper

The coronavirus disease of 2019 (COVID-19) pandemic exacerbated barriers to care for people living with human immunodeficiency virus (HIV) (PLWH). The quick uptake of telemedicine in the outpatient setting provided promise for care continuity. In …