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Internal Medicine Infectious Disease

Infectious Disease

18-04-2024 Tuberculosis News

Shortened rifampicin regimen promising as a tuberculosis preventive treatment

A 2-month regimen of daily rifampicin at 20 mg/kg has a comparable safety profile to the standard 4-month regimen of 10 mg/kg, but an inexplicably lower completion rate.

Bacterial ventriculitis in a patient with severe periodontitis

Open Access Inflammatory Brain Disease Case Study

Poor dental health can lead to life-threatening CNS infections, even in a healthy individual. This is the first case of ventriculitis caused by an oral pathogen.

CAP misdiagnoses increase unnecessary antibiotic use

One in eight hospitalized patients, particularly those with dementia, are inappropriately diagnosed with community-acquired pneumonia.

Bacterial endocarditis caused by contact lens use

Open Access Endocarditis Case Study

A 17-year-old female presented with high fever, general fatigue, and dim eyesight. She had used colored contact lenses 3 weeks previously. Traumatic injury of the eye vessels led to systemic hematogenous infection and subsequent endocarditis. 

Viruses and hematologic malignancies

Free for a limited time Hematologic Cancer Review

A thorough understanding of the relationship between viruses and hematologic cancers can help clinicians to deliver precise therapies and monitor potential complications.

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Bacterial ventriculitis in a patient with severe periodontitis

Open Access Inflammatory Brain Disease Case Study

Poor dental health can lead to life-threatening CNS infections, even in a healthy individual. This is the first case of ventriculitis caused by an oral pathogen.

Bacterial endocarditis caused by contact lens use

Open Access Endocarditis Case Study

A 17-year-old female presented with high fever, general fatigue, and dim eyesight. She had used colored contact lenses 3 weeks previously. Traumatic injury of the eye vessels led to systemic hematogenous infection and subsequent endocarditis. 

An uncommon presentation of CRC

Open Access Colorectal Cancer Case Study

Sciatica due to Streptococcus gallolyticus infection of the spinal epidural space led to a diagnosis of colorectal cancer in a person with none of the usual signs and symptoms.

Current Reviews

COVID-19 Vaccine Hesitancy Among People Living with HIV: A Systematic Review and Meta-Analysis

COVID-19 Vaccination Substantive Review

Vaccine hesitancy is one of the top 10 threats to global health, which affects the prevalence and fatality of vaccine-preventable diseases over the world. During the COVID-19 pandemic, people living with HIV (PLWH) may have higher risks of …

Special Education Law: How the COVID-19 Pandemic Has Impacted FAPE, Child Find, and FERPA Laws

COVID-19 Review

The current article provides insight into special education law within the United States before, during, and following the COVID-19 pandemic. The article aims to update pediatric neuropsychologists on the important trends and perceptions of …

Ritonavir: 25 Years’ Experience of Concomitant Medication Management. A Narrative Review

Open Access Ritonavir Review

Ritonavir is a potent inhibitor of the cytochrome P450 3A4 enzyme and is commonly used as a pharmacokinetic (PK) enhancer in antiviral therapies because it increases bioavailability of concomitantly administered antivirals. Decades of experience …

The Impact of Cannabis Use on Cognition in People with HIV: Evidence of Function-Dependent Effects and Mechanisms from Clinical and Preclinical Studies

Approximately 38.4 million people live with human immunodeficiency virus (HIV) worldwide (UNAIDS, 2021). While advances in combination-antiretroviral therapy (cART) have reduced HIV progression, secondary effects of long-term infection arise …

Further Reading

COVID-19 severity in patients with chronic lymphocytic leukemia treated with venetoclax: a single-center observational cohort study

Open Access Chronic Lymphocytic Leukemia Research

Patients with chronic lymphocytic leukemia (CLL) are at high risk of developing severe COVID-19. The present study was undertaken to elucidate COVID-19 related morbidity and mortality in CLL patients treated with venetoclax. We present a …

The relationship between benevolence and attitudes towards preventive behaviour during the COVID-19 pandemic in Sweden

Open Access COVID-19 Original Article

The global outbreak of SARS-CoV-2 causing COVID-19 disease emerged in December 2019, leading to a great need for collective actions and accountability. Measures to mitigate the spread of infection such as physical distancing, wearing face masks …

Wide use of broad-spectrum antibiotics in very low birth weight infants with spontaneous focal intestinal perforation—is it really justified?

Open Access Carbapenem Antibiotic Research

Very low birth weight (VLBW) infants are at increased risk of spontaneous focal intestinal perforation (FIP). FIP is characterized by a localized intestinal perforation with no or minimal tissue inflammation. Unlike necrotizing enterocolitis …

Significance of colonization by antibiotic-resistant organisms prior to congenital heart disease surgery in children from low- to middle-income countries sent by non-governmental organizations to Switzerland

Open Access Antibiotic Research

Antibiotic-resistant microorganisms (AMROs) colonization rate in patients from low- to middle-income countries (LMIC) has been reported to be high, reaching 50% or more depending on the bacterial species [ 1 ]. Among such patients, children from …