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Circulatory Disease Hypertension

Hypertension

Open Access Circulatory Disease Review

How neuroimmunology affects the heart

What is the brain’s involvement in cardiovascular disease pathology? Evidence suggests that neuroimmune mechanisms may play a key role. 

Editor's Choice

Treating comorbid heart failure and hypertension

Open Access Heart Failure Review

Managing patients with acute or chronic HFpEF and concurrent hypertension is difficult. Make sure you're confident prescribing the optimal drug combination. 

What role does our diet play in hypertension?

Open Access Hypertension Review

Healthy, plant-based diets can be useful in preventing and treating hypertension. Incorporating evidence-based nutritional education into clinical care and society more broadly would help hypertension control. 

How can we better manage high blood pressure in children?

Diagnosing pediatric hypertension is difficult, and adherence to treatment guidelines is poor. What approaches and interventions can help treat these patients and reduce ensuing cardiovascular events in adulthood?

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Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

Episode 3: Unravelling resistant hypertension

Why is it so difficult to diagnose and manage?

Resistant hypertension is a difficult to treat and often misunderstood phenomenon that continues to frustrate cardiologists. 

In this episode, Professors Morris Brown and Bryan Williams debate the causes of resistant hypertension and explore novel treatment options.

Prof. Morris Brown
Prof. Bryan Williams

Case Studies

Unique presentation of memantine overdose

Open Access Medical Side Effect Case Study

Hypertensive urgency and echolalia were the most striking symptoms of memantine overdose in an elderly man with mild dementia and hypertension. Early medication review with caregivers of people with dementia is key.

Hypertension, proteinuria, and hypercalciuria in a previously healthy 3-year-old

Open Access Hypertension Case Study

A panel of experts examine the differential diagnosis for secondary hypertension in a young child, and the eventual diagnosis and management of generalized arterial calcification in infants.

Aortic isthmus massive calcifications causing secondary hypertension

Open Access Hypertension Case Study

A 63-year-old woman presented with multiple, short-succession hospital admissions for heart failure and sustained hypertension despite intensive therapy. A diagnosis of a secondary hyperaldosteronism was made, resulting from renal hypoperfusion due to narrowing of the thoracic aorta by a huge calcified plaque, mimicking an aortic coarctation.

Current Reviews

Renin-angiotensin system inhibitor use and risk of Parkinson’s disease: a meta-analysis

Open Access Parkinson's Disease Review article

Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder characterized by symptoms such as tremor, muscle rigidity, bradykinesia, and postural instability [ 1 ]. It is the predominant movement disorder among the elderly …

Management of Cardiovascular Diseases by Short-Chain Fatty Acid Postbiotics

The International Scientific Association of Probiotics and Prebiotics (ISAPP) defines “probiotics” as “microorganisms that, when consumed in adequate doses or concentrations, can benefit the consumer’s health” and comprise both bacteria (e.g. …

Evolving Applications of Echocardiography in the Evaluation of Left Atrial and Right Ventricular Strain

Open Access Echocardiography Echocardiography (JM Gardin and AH Waller, Section Editors)

Left ventricular (LV) strain is widely used in the detection of subclinical LV dysfunction (e.g., cancer treatment-related cardiac dysfunction), heart failure with preserved ejection fraction (HFpEF), the assessment of LV diastolic dysfunction …

Systematic Review Article: New Drug Strategies for Treating Resistant Hypertension—the Importance of a Mechanistic, Personalized Approach

Open Access Hypertension Review article

Resistant hypertension (RHT) is characterized by persistently high blood pressure (BP) levels above the widely recommended therapeutic targets of less than 140/90 mmHg office BP, despite life-style measures and optimal medical therapies, including …

Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
Developed by: Springer Medicine

Further Reading

Improvement in clinical features of hypercortisolism during osilodrostat treatment: findings from the Phase III LINC 3 trial in Cushing's disease

Open Access Hypertension Original Article

Cushing’s disease, the most common form of endogenous Cushing’s syndrome, is a rare and debilitating condition caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary tumour, resulting in excessive secretion of cortisol from the …

Adverse Events as Potential Predictive Factors of Activity in Patients with Advanced HCC Treated with Atezolizumab Plus Bevacizumab

Open Access Hepatocellular Carcinoma Original Research

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and accounts for approximately 90% of cases [ 1 ]. Recently, the therapeutic armamentarium available for the systemic treatment of this disease has expanded. Sorafenib …

Renin-angiotensin system inhibitor use and risk of Parkinson’s disease: a meta-analysis

Open Access Parkinson's Disease Review article

Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder characterized by symptoms such as tremor, muscle rigidity, bradykinesia, and postural instability [ 1 ]. It is the predominant movement disorder among the elderly …

Evolving Applications of Echocardiography in the Evaluation of Left Atrial and Right Ventricular Strain

Open Access Echocardiography Echocardiography (JM Gardin and AH Waller, Section Editors)

Left ventricular (LV) strain is widely used in the detection of subclinical LV dysfunction (e.g., cancer treatment-related cardiac dysfunction), heart failure with preserved ejection fraction (HFpEF), the assessment of LV diastolic dysfunction …