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Hematology

Liquid biopsy may help predict cancer-associated VTE

Liquid biopsies could help to identify patients with cancer who have an increased risk for venous thromboembolism.

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Editor's Choice

Eosinophilic cystitis in an infant

Free for a limited time Cystitis Case Study

Eosinophilic cystitis is a rare, easily treatable, and important differential of bladder mass in children, which may present with an atypical obstructive uropathy.

Managing toxicities of CAR T-cell therapy

Open Access CAR T-Cell Therapy Review

A practical guide to the diagnosis, management, and treatment of complications associated with CAR T cell-therapy, ranging from cytokine release syndrome to neurotoxicity.

Liberal vs restrictive transfusion strategy for TBI

A liberal transfusion strategy does not reduce the risk for an unfavorable neurological outcome after traumatic brain injury compared with a restrictive strategy.

Thrombocytopenia in patients with sepsis: a practical approach

Open Access Thrombocytopenia Review

What are the possible causes of thrombocytopenia in patients with sepsis? Learn more in this review and discover a novel practical approach to diagnosis and treatment.

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Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe
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SPONSORED

Challenges in advanced Cutaneous T-cell Lymphoma (CTCL) – diagnosis and management

Webinar | 10-06-2024 | 16:30 (CEST)

A multidisciplinary team of speakers provide practical guidance on managing patients with cutaneous T-cell lymphoma. 

Learn about the key aspects of diagnosis and treatment via a series of patient cases.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare
Watch now to earn CME points

Case Studies

Eosinophilic cystitis in an infant

Free for a limited time Cystitis Case Study

Eosinophilic cystitis is a rare, easily treatable, and important differential of bladder mass in children, which may present with an atypical obstructive uropathy.

Severe cobalamin C deficiency

Open Access Metabolic Disease in Childhood Case Study

Nephrotic syndrome is usually caused by primary renal disorders, but you should consider metabolic diseases in atypical cases. This 7-month-old presented with nephrotic syndrome, malignant hypertension, and hemolytic anemia.

Hodgkin lymphoma masquerading as ocular inflammation

Open Access Hodgkin Lymphoma Case Study

A 17-year-old presented with non-necrotizing scleritis, anterior uveitis, vitritis, yellowish chorioretinal lesions, papillitis, and vasculitis. Would you consider Hodgkin lymphoma in the differential diagnosis?

Case-based insights: Oncology and hematology (Link opens in a new window)


Refresh your knowledge in oncology and hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now

Current Reviews

Three cases of relapsed eosinophilic sinusitis without eosinophilia during mepolizumab maintenance therapy for eosinophilic granulomatosis with polyangiitis

Mepolizumab CASE BASED REVIEW

We present three cases of eosinophilic granulomatosis with polyangiitis (EGPA) where patients experienced relapse of eosinophilic sinusitis without peripheral eosinophilia while on remission maintenance therapy with mepolizumab (MPZ), an …

Clinical characteristics and management of paroxysmal nocturnal haemoglobinuria in Latin America: a narrative review

Open Access Eculizumab Review

Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, complement-associated, haematological disorder. The level of knowledge about the disease and its management varies around the world. This narrative review provides an overview of available …

Understanding, assessing and treating immune, endothelial and haemostasis dysfunctions in bacterial sepsis

Septicemia Narrative Review

The interplay between the immune system, coagulation, and endothelium is critical in regulating the host response to infection. However, in sepsis and other critical illnesses, a dysregulated immune response can lead to excessive alterations in …

Maintenance treatment with oral anticancer agents after first-line chemotherapy in patients with recurrent or metastatic nasopharyngeal carcinoma: a systematic review and meta-analysis

Maintenance Therapy Review Article

The latest evaluation by GLOBOCAN 2020 indicates that approximately 133,354 new cases and 80,008 new deaths of nasopharyngeal carcinoma (NPC) have been recorded, making up 0.7% and 0.8% of total cancer, respectively. More men than women were …

CME & eLearning

SPONSORED

Webinar

1.5 European CME credits (ECMEC®s)

A series of patient cases underpin this interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare

Symposium (Link opens in a new window)

An independent symposium at the 10th COMy World Congress focusing on BCMA-targeting strategies for the treatment of multiple myeloma. Gain insights into the latest clinical data and the implications for clinical practice.

Supported by:
  • GlaxoSmithKline
Developed by: Springer Healthcare IME
SPONSORED

Webinar

In this live webinar, Professor Martin Dreyling and an esteemed international panel of CAR T-cell therapy experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK. 

Sponsored by:
  • Novartis Pharma AG
Developed by: Springer Healthcare

Further Reading

Renal vascular lesions in childhood-onset lupus nephritis

Open Access Lupus Nephritis Original Article

Kidney involvement is common in childhood-onset systemic lupus erythematosus (cSLE), occurring in around 50–80% of patients [ 1 , 2 ]. Around 4% of cSLE develop advanced chronic kidney disease (CKD) [ 2 , 3 ]. Up to 15% of patients with …

Clinical characteristics and management of paroxysmal nocturnal haemoglobinuria in Latin America: a narrative review

Open Access Eculizumab Review

Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, complement-associated, haematological disorder. The level of knowledge about the disease and its management varies around the world. This narrative review provides an overview of available …

Trilaciclib use in extensive-stage small cell lung cancer (ES-SCLC): are clinical benefits seen in the real-world setting?

Open Access SCLC Research

Extensive-stage small cell lung cancer (ES-SCLC) represents a therapeutic challenge due to the aggressive nature of tumor growth, early metastatic spread, and the lack of targetable mutations [ 1 ]. Nonetheless, platinum-based cytotoxic …

Mucositis-associated bloodstream infections in adult haematology patients with fever during neutropenia: risk factors and the impact of mucositis severity

Open Access Neutropenia Research

Patients receiving myelotoxic treatment for haematological malignancies are at high risk for bloodstream infections (BSI) and sepsis, which brings about a significant risk of intensive care admission and treatment-related mortality [ 1 ]. Many …