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Hematology

Open Access Cancer Therapy Review

ADCs in cancer: key data for currently approved agents

Delve into the efficacy and safety data for the antibody–drug conjugates currently approved by the US FDA across tumor types such as hematologic, genitourinary, and gynecologic cancers.

Viruses and hematologic malignancies

Free for a limited time Hematologic Cancer Review

A thorough understanding of the relationship between viruses and hematologic cancers can help clinicians to deliver precise therapies and monitor potential complications.

Novel therapeutic targets in AML

Open Access Acute Myeloid Leukemia Review

Many more targeted therapies are now available for people with AML, in both the newly diagnosed and relapsed/refractory settings. Learn about the genetic and protein targets, and their associated therapeutics, in this review.

Doxorubicin use may increase breast cancer risk in adult Hodgkin’s lymphoma survivors

20-03-2024 Hodgkin Lymphoma News

Adolescent and adult survivors of Hodgkin’s lymphoma have a higher risk for developing breast cancer if they receive doxorubicin than if they do not.

Severe megaloblastic anemia related to erlotinib

Open Access NSCLC Case Study

The first case of severe megaloblastic anemia in a patient treated with erlotinib for advanced NSCLC. It highlights the need for close clinical and blood monitoring in people receiving long-term TKI therapy.

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Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe

Case Studies

Severe megaloblastic anemia related to erlotinib

Open Access NSCLC Case Study

The first case of severe megaloblastic anemia in a patient treated with erlotinib for advanced NSCLC. It highlights the need for close clinical and blood monitoring in people receiving long-term TKI therapy.

Primary thyroid lymphoma: a case series

Open Access Thyroid Cancer Case Study

Although rare, primary thyroid lymphoma should be considered in cases of rapidly growing goiters. Timely needle biopsy can avoid unnecessary surgery.

Successful management of ATO-induced acute pericarditis

A patient receiving arsenic trioxide for acute promyelocytic leukemia developed drug-induced acute pericarditis that was successfully treated with colchicine.

Live Webinar | 10-06-2024 | 16:30 (CEST)

Challenges in advanced CTCL – diagnosis and management

Live: Monday 10 June 2024, from 16:30 – 18:00 (CEST)

In this live interactive webinar, a multidisciplinary team of speakers will provide practical guidance on managing patients with cutaneous T-cell lymphoma. Learn about the key aspects of diagnosis and treatment via a series of patient cases.

Sponsored by: Kyowa Kirin

Developed by: Springer Healthcare

Current Reviews

Venous Thrombosis in Acute Pancreatitis: What to and Not to Do?

Acute Pancreatitis Invited Reviews

Acute pancreatitis is an acute inflammatory condition of the pancreas that has not only local but systemic effects as well. Venous thrombosis is one such complication which can give rise to thrombosis of the peripheral vasculature in the form of …

Narrative Review on the Use of Cladribine Tablets as Exit Therapy for Stable Elderly Patients with Multiple Sclerosis

Open Access Cladribine Review

The number of ageing people with relapsing multiple sclerosis (RMS) is increasing. The efficacy of disease-modifying therapies (DMTs) for RMS declines with age. Also, older persons with MS may be more susceptible to infections, hospitalisations …

Clinical guidelines for prevention and treatment of CAT in Japan and other countries

Direct Oral Anticoagulant Progress in Hematology

Cancer-associated thrombosis (CAT) is an important prognostic factor for an increasing number of cancer patients. Understanding of CAT among cancer care providers has grown in recent years, and guidelines for the prevention and treatment of CAT …

Hereditary TTP/Upshaw–Schulman syndrome: the ductus arteriosus controls newborn survival

Hereditary TTP (hTTP), termed Upshaw–Schulman syndrome, is an ultra-rare disorder caused by a severe deficiency of plasma ADAMTS13 activity that allows circulation of ultra-large von Willebrand factor (UL-VWF) multimers. The greatest risk for hTTP …

Case-Based Insights: Oncology and Hematology (Link opens in a new window)


Refresh your knowledge in Oncology and Hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now
SPONSORED

Webinar

A series of patient cases underpin this live interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare

eLearning | Interviews (Link opens in a new window)

This independent educational program aims to highlight advances in the diagnosis, treatment, and management of patients with hemophilia that have the potential to improve patients’ outcomes and quality of life.

Supported by:
  • Sanofi
Developed by: Springer Healthcare IME

Cases

Take on interactive case studies with a focus on hematology. Each case has been prepared by renowned experts in the field and features knowledge-check questions with answers to help keep you and your practice up to date.

Developed by: Springer Medizin

Further Reading

Intramyocardial abscess and endoventricular thrombosis: a complex case

Open Access Endocarditis Case Report

Infective endocarditis (IE) is today a public health problem, as the recent ESC Guidelines have also recalled. Abscesses can be complications of IE and their presence means that the infection is not controlled. We describe the complex case of a …

High-risk coronary plaque of sudden cardiac death victims: postmortem CT angiographic features and histopathologic findings

Open Access Sudden Cardiac Death Original Article

High-risk coronary plaques (HRP) are characterized in clinical radiological imaging by the presence of low plaque attenuation, a napkin-ring sign (NRS), spotty calcifications (SC) and a positive remodeling index (RI). To evaluate if these signs …

Outcome 10 years after Shiga toxin-producing E. coli (STEC)-associated hemolytic uremic syndrome: importance of long-term follow-up

Open Access Hemolytic Uremic Syndrome Original Article

Hemolytic uremic syndrome (HUS) is defined by the triad of hemolytic anemia, thrombocytopenia, and acute kidney injury (AKI). Infections with enterohemorrhagic Escherichia coli (EHEC) and subsequent translocation of Shiga toxin from the gut into …