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What are the clinical and pathological features of immune thrombocytopenia secondary to systemic lupus erythematosus and Sjögren syndrome? And how can current and emerging therapeutic strategies improve outcomes?
Updated guideline from the German Society for Hematology and Medical Oncology on the prevention, diagnosis, and management of community-acquired respiratory virus infections in people with cancer.
Long-term monitoring for portal hypertension is important – even after resolution of acute sinusoidal obstruction syndrome and achievement of leukemia remission – to optimize outcomes in inotuzumab ozogamicin-treated patients.
Glucocorticoids are cornerstone agents in oncology due to their potent anti-inflammatory, immunosuppressive, and antitumor properties. But it is crucial to strike a balance between therapeutic benefit and harm.
Among people with cancer, the presence of fatigue before starting treatment is associated with an increased risk for severe, life-threatening, or fatal adverse events.
Learn more about the importance of adapting treatment approaches for special patient populations (eg, elderly or pregnant patients) in this third module of our interactive e-Learning program on diagnosing and treating aplastic anemia.
Are you up to date on targeted therapies for relapsed/refractory AML?
Join Prof. Amer Zeidan and his expert guests to hear about innovations in molecular testing, emerging therapies, and IDH-targeted treatments, and get practical advice for improving your patient care.
Supported by: independent educational grant from Rigel
This podcast summarises updated European Renal Best Practice and UK Kidney Association guidelines on treating anemia in CKD. With a focus on hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) as an alternative to erythropoiesis‐stimulating agents, and key considerations for clinical practice.
Long-term monitoring for portal hypertension is important – even after resolution of acute sinusoidal obstruction syndrome and achievement of leukemia remission – to optimize outcomes in inotuzumab ozogamicin-treated patients.
Common infections can trigger macrophage activation syndrome. This case of a 10-year-old girl developing MAS during the convalescence period after varicella highlights the complexities of MAS diagnosis.
A case illustrating a rare but important association between Behçet disease and Hodgkin lymphoma, possibly mediated by immune dysregulation and chronic immunosuppression.
Marking a major milestone in chronic myeloid leukemia treatment
Tyrosine kinase inhibitors have transformed the treatment of chronic myeloid leukemia, a condition that had limited therapeutic options before.
In this 25th year since the first phase 2 trials of the first TKI, we speak to a researcher and clinician who has been involved since the early days. Dr. Jorge Cortes shares his experience and talks about the impact of these drugs, not only in the treatment of CML but also more widely.
Chemotherapy remains a mainstay in managing advanced and metastatic solid tumors, but its hematologic toxicity may restrict its application [ 1 ]. Chemotherapy-induced myelosuppression (CIM) is one of the common side effects of systemic …
Several similarities and differences have been reported in the epidemiology and clinical characteristics of adult eosinophilic esophagitis (EoE) between Japan and Western countries. To review the similarities and differences in adult EoE between …
Inflammatory rheumatic diseases (IRDs) compromise vascular integrity through systemic inflammation and (auto) immune reactions, which are associated with an increased risk of vascular complications. Venous stasis, endothelial dysfunction, and …
Endothelial dysfunction, inflammation, atherosclerosis, thrombosis, and extracellular matrix remodeling represent the key pathophysiological processes underlying cardiovascular diseases. Heparanase, the sole mammalian endo-β-D-glucuronidase that …
Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Learn more about novel biomarkers for diagnosis and monitoring, and familiarize yourself with current and emerging targeted therapies.
Professor Joy Ho and a panel of Asia-Pacific-based experts will examine real-life patient cases in this Masterclass, exchanging insights into their clinical experiences of using CAR T-cell therapy to treat patients with R/R DLBCL or R/R FL.
This educational activity is not intended for healthcare professionals based in the UK, US, or off-label Asia-Pacific countries.
This hub presents a curated selection of educational materials focused on the latest clinically relevant topics related to the use of chimeric antigen receptor (CAR) T‑cell therapy for the treatment of relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) and R/R follicular lymphoma (FL).
This content has been developed in collaboration with and funded by the sponsor Novartis Pharma AG and is not intended for healthcare professionals based in the UK and US.
Hear directly from experts in acute myeloid leukemia about innovations in molecular testing, emerging therapies, and targeted treatments, and get practical advice for improving the care of your patients with relapsed or refractory disease.
Mechanisms of bioprosthetic heart valve (BHV) dysfunction include structural deterioration, non-structural valve dysfunction, endocarditis, and thrombosis. Amongst these, thrombosis and leaflet fibrosis (as a component of structural valve …
Discussion remains concerning the safety and tolerability of anti-thymocyte globulin (ATG)-based immunosuppressive therapy (IST) in older patients with aplastic anaemia (AA). Using data of 127 consecutive patients from the Dutch adult AA registry …
Glanzmann Thrombasthenia (GT) is a congenital platelet disorder characterized by a life-long bleeding tendency, historically considered protective against thrombosis. This report describes a rare case of pulmonary embolism (PE) in a patient with …
The outcomes of children with aplastic anemia receiving cyclosporine monotherapy vary significantly in terms of mortality risk; therefore, a prognostic model for predicting mortality risk was constructed to optimize risk-stratified treatment …
Updated guideline from the German Society for Hematology and Medical Oncology on the prevention, diagnosis, and management of community-acquired respiratory virus infections in people with cancer.