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Clinical Collections
Women’s Health Knowledge Hub Advances in Alzheimer’s

Navigating neuroimaging in Alzheimer disease care

PET imaging is playing an increasingly critical role in managing AD, but how can you effectively integrate it into clinical practice? Our expert-led program will empower you with practical strategies and real-world case studies.

This content is intended for healthcare professionals outside of the UK.
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Hematology

AML secondary to CAR T-cell therapy

A patient who received CAR T-cell therapy for refractory/relapsed multiple myeloma developed acute myeloid leukemia, highlighting the need for long-term and close monitoring after such treatment.

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Editor's Choice

Surprise passenger as cause of severe anemia

  • Open Access
  • Anemia
  • Case Study

Blood-tinged saliva, light-headedness, difficulty speaking and a foreign body sensation in the throat were all reported by a 65-year-old man with severe anemia. The cause? Oropharyngeal leech infestation.

Managing septic shock in a pediatric AML patient

A 10-year-old boy exhibited persistent pancytopenia following treatment for mucormycosis, with further diagnosis revealing AML. Septic shock soon followed, but was successfully managed with combined CRRT and CytoSorb therapy.

Half-dose apixaban for cancer patients at risk for recurrent VTE

Patients requiring extended thromboprophylaxis after a first episode of cancer-related venous thromboembolism can be given a low dose of the factor X inhibitor apixaban.

Epigenetic drugs in cancer therapy

Epigenetic modifications are dysregulated in several cancers, making them therapeutic targets. Delve into the current and future use of epigenetic drugs for the treatment of solid and hematologic malignancies.

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Keynote webinar | Spotlight on advances in lupus

  • Live
  • Webinar | 27-05-2025 | 18:00 (CEST)

Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Join this session to learn more about novel biomarkers for diagnosis and monitoring and familiarise yourself with current and emerging targeted therapies.

Join us live: Tuesday 27th May, 18:00-19:15 (CEST)

Prof. Edward Vital
Prof. Ronald F. van Vollenhoven
Developed by: Springer Medicine
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Webinar

Latest News

Half-dose apixaban for cancer patients at risk for recurrent VTE

Diabetes risk increased with hemochromatosis variant regardless of transferrin and ferritin

Promising response to loncastuximab tesirine in lymphoma

Transplantation can be omitted for certain MCL patients

inMIND supports tafasitamab addition in follicular lymphoma

AI quantification of sickle cell morphology as an objective disease marker of SCD

SPONSORED

Recent advances in the use of CAR T-cell therapies in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma

In this webinar, Professor Martin Dreyling and an esteemed international panel of CAR T-cell therapy experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK.

Sponsored by:
  • Novartis Pharma AG
Chaired by: Prof. Martin Dreyling
Developed by: Springer Healthcare
Watch now
Video

Case Studies

AML secondary to CAR T-cell therapy

A patient who received CAR T-cell therapy for refractory/relapsed multiple myeloma developed acute myeloid leukemia, highlighting the need for long-term and close monitoring after such treatment.

Surprise passenger as cause of severe anemia

  • Open Access
  • Anemia
  • Case Study

Blood-tinged saliva, light-headedness, difficulty speaking and a foreign body sensation in the throat were all reported by a 65-year-old man with severe anemia. The cause? Oropharyngeal leech infestation.

Managing septic shock in a pediatric AML patient

A 10-year-old boy exhibited persistent pancytopenia following treatment for mucormycosis, with further diagnosis revealing AML. Septic shock soon followed, but was successfully managed with combined CRRT and CytoSorb therapy.

Elevate your expertise in aplastic anemia (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME
Learn more

Current Reviews

Advancements in research on the thrombo-inflammation mechanisms mediated by factor XII in ischemic stroke

Ischemic stroke (IS) is a major cause of mortality and disability, with thrombo-inflammation constituting a core pathophysiological mechanism. This process is closely linked to coagulation cascade activation, endothelial injury, immune cell …

Vitamin B12 Deficiency in Children

Vitamin B12 deficiency poses significant health care challenges. Its deficiency is an important cause of nutritional anemia in children, next to iron deficiency. Though macrocytic/ megaloblastic anemia due to deficiency of vitamin B 12, is the …

Safety and effectiveness of diroximel fumarate in relapsing forms of multiple sclerosis: a systematic review and meta-analysis

Multiple sclerosis (MS) is a chronic, immune-mediated disease characterized by inflammation of the central nervous system (CNS), demyelination, and axonal degeneration. It is estimated to affect more than 2.9 million people worldwide. The major …

Left atrial appendage occlusion in patients with cancer

Atrial fibrillation (AF) and malignancy share a complex relationship, significantly complicating patient management. Patients with cancer, particularly those with lung, gastrointestinal, genitourinary, and hematologic malignancies, are at …

Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe
Listen now
Podcast

CME & eLearning

eLearning (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME
SPONSORED

Webinar

1.5 European CME credits (ECMEC®s)

A series of patient cases underpin this interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare

Symposium (Link opens in a new window)

An independent symposium at the 10th COMy World Congress focusing on BCMA-targeting strategies for the treatment of multiple myeloma. Gain insights into the latest clinical data and the implications for clinical practice.

Supported by:
  • GlaxoSmithKline
Developed by: Springer Healthcare IME

Further Reading

Clinical Performance of the Brain4care System for Noninvasive Detection of Intracranial Hypertension

Intracranial pressure (ICP) monitoring is an important parameter in neurocritical care for managing conditions such as traumatic brain injury (TBI), hydrocephalus, and intracranial hemorrhage. Traditionally, ICP is measured using invasive …

Molecular predictors of venous and arterial thrombotic events in patients with myelofibrosis

While patients with myelofibrosis (MF) face an elevated risk of thrombosis, no validated scoring system currently exists to effectively assess this specific risk. This study aimed to explore distinct molecular risk factors for arterial (ATE) and …

Short-term outcomes of triplet therapy in metastatic hormone-sensitive prostate cancer in older adults: a retrospective, single-center real-world cohort study

Metastatic hormone-sensitive prostate cancer (mHSPC) is a clinically and biologically diverse disease with a wide range of tumor characteristics and disease progression patterns [ 1 ]. Despite significant advancements in treatment strategies …

Decoding HbF reactivation by hydroxyurea in hemoglobinopathy patients through microRNA signatures

Hydroxyurea promotes HbF elevation in b-thalassemia and sickle cell anemia patients however, its mechanism is not completely elucidated. Previous studies have associated microRNAs with the regulation of HBG2, prompting this study to investigate …

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