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Atopic Dermatitis 

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  1. Open Access 09-05-2024 | Online First

    Treatment Preference Research in Atopic Dermatitis: A Systematic Review of Quantitative Studies

    The development and availability of therapies for skin conditions that fulfill patients’ needs is of utmost importance, as these disorders negatively affect patients’ physical and mental well-being [ 1 – 5 ]. Atopic dermatitis (AD) is a chronic …

  2. 01-07-2024 | Atopic Dermatitis | Letter

    Metabolic effects of upadacitinib in patients with psoriasis and atopic dermatitis

    Upadacitinib, a selective JAK-1 inhibitor, is FDA-approved for treating psoriatic arthritis (PsA) and atopic dermatitis (AD) [ 1 – 3 ]. Although found to be effective and safe in clinical trials, it has been associated with metabolic abnormalities …

  3. Open Access 18-04-2024 | Dupilumab | ReviewPaper

    Comparison of Old and New Systemic Treatments for Moderate to Severe Atopic Dermatitis

    Atopic Dermatitis (AD) is a chronic inflammatory skin disorder that affects 7% of adults and up to 20% of children across the world [ 1 ]. It often presents in childhood and can persist into adulthood. The presentation commonly involves skin …

  4. Open Access 01-07-2024 | Atopic Dermatitis | ReviewPaper

    Effectiveness of atopic dermatitis patient education programs – a systematic review and meta-analysis

    Patient education in atopic dermatitis (AD) has worked in parallel to the gold standard of pharmacological treatment as a foundational component of therapeutic regimens. In addition to improving patient education, past investigations of …

  5. Open Access 04-05-2024 | Atopic Dermatitis | Online First

    Real-World Clinical, Psychosocial, and Economic Burden of Atopic Dermatitis: Results From the ESSENTIAL AD Multicountry Study

    Atopic dermatitis (AD) is a common inflammatory skin disease characterized by the development of highly pruritic eczematous lesions and considerable quality of life and socioeconomic impact on patients and their families [ 1 , 2 ]. The optimal …

  6. 06-04-2024 | Atopic Dermatitis | Online First

    Atopic dermatitis: treatment and innovations in immunotherapy

    Atopic dermatitis (AD) is a common inflammatory skin disease characterized by itching and skin barrier dysfunction. Moderate to severe AD is often refractory to first-line topical treatments, and systemic immunosuppressants have been shown to be …

  7. Open Access 18-01-2024 | Atopic Dermatitis | ReviewPaper

    OX40 in the Pathogenesis of Atopic Dermatitis—A New Therapeutic Target

    Atopic dermatitis (AD) is a chronic, heterogeneous, inflammatory disease characterized by skin lesions, pruritus, and pain [ 1 , 2 ]. It is the most common inflammatory skin disease that affects nearly 20% of children, 15% of adolescents, and 10% …

  8. Open Access 10-02-2024 | Atopic Dermatitis | Erratum

    Correction to: OX40 in the Pathogenesis of Atopic Dermatitis—A New Therapeutic Target

  9. 29-01-2024 | Atopic Dermatitis | ReviewPaper

    Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis?

    Food allergy in atopic dermatitis is mediated by complex immune interactions between genetics, diet, environment, and the microbiome. When contact between inflamed skin and food antigens occurs, contact hypersensitivity can develop. Consequently …

  10. Open Access 23-04-2024 | Atopic Dermatitis | Online First

    Economic Burden of Itch-Related Sleep Loss in Moderate-to-Severe Atopic Dermatitis in the United Kingdom

    Atopic dermatitis (AD) is a chronic skin condition characterized by erythema, intense itching and dry, cracked, scaly skin in the folds of joints, back of the hands or scalp [ 1 ]. The condition usually begins in early infancy, with a prevalence of …

  11. Open Access 02-05-2024 | Atopic Dermatitis | Online First

    Upadacitinib Rapidly Improves Patient-Reported Outcomes in Atopic Dermatitis: 16-Week Results from Phase 3 Clinical Trials (Measure Up 1 and 2)

    Atopic dermatitis (AD) is a chronic, inflammatory skin condition characterized by pruritus and skin lesions with typical eczematous morphology that affects approximately 2.7% of the global population and up to 20% of children [ 1 , 2 ]. Patients …

  12. Open Access 02-05-2024 | Ruxolitinib | Online First

    Efficacy, Safety, and Long-Term Disease Control of Ruxolitinib Cream Among Adolescents with Atopic Dermatitis: Pooled Results from Two Randomized Phase 3 Studies

    Atopic dermatitis (AD) is a highly pruritic, inflammatory skin disease [ 1 ] that typically begins in childhood. Globally, the prevalence of AD is approximately 7% in adolescents from 12 to < 18 years old, although reported rates vary [ 2 – 4 ]. AD …

  13. 05-04-2024 | Atopic Dermatitis | Online First

    Secondary Bacterial Infections in Patients with Atopic Dermatitis or Other Common Dermatoses

    Secondary bacterial infections of common dermatoses such as atopic dermatitis, ectoparasitosis, and varicella zoster virus infections are frequent, with Staphylococcus aureus and Streptococcus pyogenes being the bacteria most involved. There are …

  14. Open Access 02-05-2024 | Dupilumab | Online First

    Correction to: Efficacy and Safety of Dupilumab Treatment with Concomitant Topical Corticosteroids in Children Aged 6 Months to 5 Years with Severe Atopic Dermatitis

  15. Open Access 28-03-2024 | Atopic Dermatitis | OriginalPaper

    Maintenance of Investigator’s Static Global Assessment Response with Once-Daily Crisaborole in Participants with Mild to Moderate Atopic Dermatitis

    Atopic dermatitis (AD) is a complex chronic immuno-inflammatory skin disease characterized by dry skin, intense pruritus, and recurrent eczematous lesions [ 1 – 3 ]. Topical corticosteroids (TCSs) are traditionally considered the mainstay …

  16. Open Access 24-02-2024 | Atopic Dermatitis | OriginalPaper

    Atopic dermatitis in early life and pain at 10 years of age: An exploratory study

    Pain is a distinctive burden in atopic dermatitis and recognized as an important and highly prevalent symptom. It is unknown if the presence of atopic disease may sensitize children to adverse pain profiles in the long term. We aimed to assess the …

  17. Open Access 27-12-2023 | Atopic Dermatitis | OriginalPaper

    Characterization of Different Inflammatory Skin Conditions in a Mouse Model of DNCB-Induced Atopic Dermatitis

    The mouse model of 2,4-dinitrochlorbenzene (DNCB)-induced human-like atopic dermatitis (hlAD) has been widely used to test novel treatment strategies and compounds. However, the study designs and methods are highly diverse, presenting different …

  18. Open Access 03-05-2024 | Atopic Dermatitis | Online First

    Lebrikizumab Provides Rapid Clinical Responses Across All Eczema Area and Severity Index Body Regions and Clinical Signs in Adolescents and Adults with Moderate-to-Severe Atopic Dermatitis

    This article is published with digital features, including an animation, to facilitate understanding of the article. To view digital features for this article go to https://doi.org/10.6084/m9.figshare.25533682 …

  19. Open Access 13-04-2024 | Dupilumab | OriginalPaper

    Matching-Adjusted Indirect Comparison of the Efficacy at Week 32 of Tralokinumab and Dupilumab in the Treatment of Moderate-to-Severe Atopic Dermatitis

    Atopic dermatitis (AD) is a chronic, relapsing–remitting, inflammatory skin condition characterised by pruritus and eczematous lesions [ 1 , 2 ]. For adults with moderate-to-severe AD, the effect on health-related quality of life can be …

  20. Open Access 21-03-2024 | Atopic Dermatitis | OriginalPaper

    Management of Patients Affected by Moderate-to-Severe Atopic Dermatitis with JAK Inhibitors in Real-World Clinical Practice: An Italian Delphi Consensus

    Atopic dermatitis (AD) is one of the most common inflammatory skin diseases worldwide [ 1 ]. AD usually presents with eczematous patches and intense itch that can significantly impair patients’ quality of life and productivity [ 1 ]. For decades …

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