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Progesterone 

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  1. Open Access 23-04-2024 | Progesterone | Review

    Diagnostic and therapeutic use of oral micronized progesterone in endocrinology

    Micronized progesterone can be used for the diagnosis and therapy of various endocrine conditions, from amenorrhea to premenstrual syndrome, PCOS, perimenopause, and menopause.

  2. 19-02-2024 | Dydrogesterone | OriginalPaper

    The combination of dydrogesterone and micronized vaginal progesterone can render serum progesterone level measurements on the day of embryo transfer and rescue attempts unnecessary in an HRT FET cycle

    Recent years have seen a distinct shift in the embryo transfer (ET) strategies in assisted reproductive technology (ART) treatments from fresh to frozen ET (FET) [ 1 , 2 ]. Despite the increase in FET cycles, there is no consensus on the “optimal” …

  3. Open Access 01-12-2024 | Progesterone | OriginalPaper

    Progesterone-induced progesterone receptor membrane component 1 rise-to-decline changes are essential for decidualization

    Human endometrium tissue is highly dynamic going through proliferative, secretory, and menses phases during a regular menstrual cycle [ 1 – 3 ]. Correspondingly, its functional layer exhibits steroid hormone-dependent proliferation …

  4. 27-04-2024 | Dydrogesterone | Online First

    Impact of dydrogesterone use in cycles with low progesterone levels on the day of frozen embryo transfer

    Both the number of IVF/ICSI cycles and frozen embryo transfers (FET) have increased in the last few years. In 2017, more than 270,000 cycles were reported in Europe [ 1 ], with pregnancy rates ranging between 30.2% (autologous oocytes) and 41.1% …

  5. Open Access 01-12-2024 | Progesterone | OriginalPaper

    Progesterone therapy for prevention of recurrent spontaneous preterm birth in a minority patient population: a retrospective study

    Preterm birth (PTB) is a significant challenge to human health worldwide and remains a leading cause of infant mortality in the United States [ 1 – 3 ]. Prematurity increases the risk of death from other causes and is associated with significant …

  6. 01-02-2024 | Progesterone | News

    Progesterone

    Dermatitis
  7. 19-03-2024 | Dydrogesterone | OriginalPaper

    Comparison between oral dydrogesterone versus micronized vaginal progesterone gel in clinical outcome within the first HRT-FET cycle: a retrospective analysis

    Since 1983, frozen-thawed embryo transfers (FET) have been widely performed around the world [ 1 ]. After years of development, embryo freezing technology has become very mature leading to a higher accumulated pregnancy rate. Compared to fresh …

  8. Open Access 03-04-2024 | Progesterone | Online First

    Can serum progesterone concentration direct a fresh or freeze-all transfer strategy in the first in vitro fertilisation cycle?

    Historically, most fertility clinics worldwide have practiced fresh embryo transfer, with frozen transfer of surplus embryos. Fresh embryo transfer is associated with increased chances ovarian hyperstimulation and studies suggest that there are …

  9. 01-02-2024 | Progesterone | News

    Progesterone

    Foreign body granuloma following exposure during first trimester of pregnancy
  10. Open Access 16-02-2024 | Progesterone | OriginalPaper

    Mature oocyte dysmorphisms may be associated with progesterone levels, mitochondrial DNA content, and vitality in luteal granulosa cells

    The clinical pregnancy rates following intracytoplasmic sperm injection (ICSI) continue to be around 30%, indicating that there is still room for advancement in this area [ 1 , 2 ]. Several systematic reviews and meta-analyses indicated that the …

  11. Open Access 01-12-2024 | Progesterone | OriginalPaper

    Corpus luteum presence in the bovine ovary increase intrafollicular progesterone concentration: consequences in follicular cells gene expression and follicular fluid small extracellular vesicles miRNA contents

    Follicular development requires a synchronized regulation between cellular communication and endocrine factors, to generate a viable oocyte [ 1 ]. The antral follicle contains follicular fluid (FF), which is an ultrafiltrate from blood plasma and …

  12. 29-02-2024 | Progesterone | OriginalPaper

    Comparison of progesterone protocol versus gonadotropin-releasing hormone antagonist protocol in terms of preventing premature LH surge and assisted reproductive technology outcome in infertile women: a randomized controlled trial

    The controlled ovarian stimulation (COS) protocol represents a significant advancement in assisted reproductive technology (ART) [ 1 ]. In order to enhance the effectiveness of COS, it is imperative to primarily prevent the premature surge of …

  13. Open Access 01-12-2024 | Progesterone | OriginalPaper

    Progesterone receptor distribution in the human hypothalamus and its association with suicide

    The human hypothalamus modulates mental health by balancing interactions between hormonal fluctuations and stress responses. Stress-induced progesterone release activates progesterone receptors (PR) in the human brain and triggers alterations in …

  14. Open Access 01-12-2024 | Progesterone | OriginalPaper

    Can single progesterone concentration predict miscarriage in early pregnant women with threatened miscarriage: a systematic review and meta-analysis

    About 25% of pregnant women experience bleeding in the early stage, and half of them eventually progress to pregnancy loss. Currently, neither effective treatment nor prevention strategy is available to manage this condition [ 1 – 3 ]. Despite some …

  15. 01-12-2023 | Progesterone | News

    Progesterone/withania-somnifera

    Acute liver failure: case report
  16. 19-02-2024 | Progesterone | Online First

    Cytokines and Pentraxin 3 Levels in Unexplained Recurrent Pregnancy Loss: Role of Oral Micronized Progesterone Therapy as Immunomodulator on Their Levels and Pregnancy Outcome, a Prospective Comparative Study

    Recurrent pregnancy loss (RPL) remains unexplained in one-third cases [ 1 ]; hence, specific treatment cannot be offered, and this subset of RPL is treated only empirically. The immunobiological role of cytokines in human pregnancy is the focus of …

  17. 22-04-2023 | Progesterone | OriginalPaper

    Decreased serum allopregnanolone and progesterone levels in male patients with bipolar disorder and their effects on cognitive functions

    The progression of bipolar disorder (BD) is characterized by recurrent episodes of depression, mania, and hypomania, thus affecting the daily functionality of individuals. Previous studies have shown that a large proportion of patients diagnosed …

  18. Open Access 01-12-2023 | Progesterone | OriginalPaper

    A molecular toolbox to study progesterone receptor signaling

    Progesterone receptor (PR) signaling is required for mammary gland development and homeostasis. A major bottleneck in studying PR signaling is the lack of sensitive assays to measure and visualize PR pathway activity both quantitatively and …

  19. 01-08-2023 | Miscarriage | News

    Progesterone

    Foreign body granuloma at the injection site: case report
  20. 01-10-2023 | Meningioma | News

    Progesterone congeners may increase risk of meningioma

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