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ESC Congress 2023

Optical coherence tomography may be a good option for guiding PCI

Optical coherence tomography appears to be superior to angiography and noninferior to intravascular ultrasound for guiding PCI.

Mavacamten shows long-term efficacy in obstructive hypertrophic cardiomyopathy

11-09-2023 Cardiomyopathy News

Long-term mavacamten helps patients with symptomatic obstructive hypertrophic cardiomyopathy avoid septal reduction therapy, but may be linked to left ventricular systolic dysfunction.

Sick sinus syndrome: sparing the atrium does not pay off

07-09-2023 Cardiac Arrhythmia News

Is too much atrial pacing associated with atrial fibrillation? The DANPACE II study argues it isn't.

Is personalized diuresis useful in acute heart failure

07-09-2023 Acute Heart Failure News

Should loop diuretics be dosed in acute heart failure based on urinary sodium levels? The PUSH-AHF study has investigated this and provides interesting results.

Local hospital care for non-ST-elevation out-of-hospital cardiac arrest

05-09-2023 Circulatory Arrest News

Randomized trial findings show no survival advantage for expedited transfer to a specialist cardiac center for non-ST elevation out-of-hospital cardiac arrest.

Expert Interviews

Expert commentary on the management of cardiovascular disease in patients with diabetes

Professor Nikolaus Marx discusses the new ESC guidelines on screening and stratification of patients with diabetes, and the importance of person-centred therapeutic strategies to reduce patients' cardiovascular risk.

Expert commentary on the management of cardiomyopathies

Cardiomyopathy Expert Interview

Professor Johann Bauersachs discusses the new ESC guidelines on cardiomyopathy, which for the first time cover the broad range of cardiomyopathies. He highlights some red flags for diagnosis, and the importance of patient involvement in disease management. 

Expert commenary on iron supplementation therapy and heart failure

Heart Failure Expert Interview

Professor Michael Böhm explains the importance of treating iron deficiency in heart failure patients, considering the results of the HEART-FID trial and pooled individual patient data from three RCTs.

Unlock your free access to coverage of the ESC Congress 2023

Acoramidis proves promising in ATTR amyloidosis

06-09-2023 Cardiac Amyloidosis News

Treatment with acoramidis in people with transthyretin-mediated amyloidosis yielded a significant reduction in all-cause mortality, cardiovascular hospitalizations, and an improvement in NT-proBNP.

Little exercise in early years leads to heart damage

Those with low levels of physical activity during childhood and adolescence may be creating an environment susceptible to heart attack and stroke later in life. 

Food insecurity leads to higher BMI in patients with congestive heart failure

05-09-2023 Heart Failure News

Patients with congestive heart failure who face food insecurity in daily life have been found to have a higher mean BMI and lower albumin levels than those who are food secure.

Significant reduction in MACE with icosapent-ethyl in ASCVD and elevated triglycerides

05-09-2023 Circulatory Disease News

Icosapent-ethyl lowers the number of major adverse cardiovascular events in patients with atherosclerotic cardiovascular disease and elevated triglyceride levels.

Selected Presentations from the ESC Congress 2023

New guidelines for the management of cardiomyopathies

Watch the official ESC video recording of the presentation of the first international guideline covering all subtypes of cardiomyopathies, except HCM.

Guidelines for the management of cardiovascular disease in patients with diabetes

Watch the official ESC video recording of the presentation of the international guideline for prevention and management of CVD in patients with diabetes.

Guidelines for the management of endocarditis

Watch the official ESC video recording of the presentation of updated international guidelines for the diagnosis and management of patients with infective endocarditis.

Alirocumab effective and safe in children with familial hypercholesterolemia

05-09-2023 Hypercholesterolemia News

Alirocumab every 2 or 4 weeks is a safe and effective treatment in children and adolescents with heterozygous familial hypercholesterolemia inadequately controlled with statins.

Higher MACE risk with immune checkpoint inhibitors

04-09-2023 Cancer Immunotherapy News

Cancer patients treated with immune checkpoint inhibitors have an increased risk of major adverse cardiovascular events if they have a history of atherosclerotic cardiovascular disease or hypertension.

Consumption of ultra-processed foods confers high risk CV events

04-09-2023 Circulatory Disease News

A comprehensive analysis shows that people who consume the most ultra-processed foods have a 24% higher risk of heart attack or stroke.

Extended anticoagulation for cancer patients with isolated distal DVTs

31-08-2023 Venous Thrombosis News

The ONCO DVT trial supports extended anticoagulation with edoxaban for cancer patients with isolated distal deep vein thrombosis.

25-08-2023 Heart Failure News

Semaglutide beneficial for patients with HFpEF and obesity

STEP-HFpEF trial results point to benefit of semaglutide in patients with heart failure with preserved ejection fraction and obesity.

Lp(a) risk factor for bioprosthetic aortic valve degeneration

Serum lipoprotein (a) concentrations appear to be a risk factor for bioprosthetic aortic valve degeneration. The next step in investigating the role of lipoprotein (a) would be whether lowering it could delay bioprosthetic valve degradation.

Focused update of heart failure guidelines

30-08-2023 Heart Failure News

A focused update of the ESC's heart failure guidelines will embed the results of major new studies into current practice.

PCSK9 inhibitor rarely started within 1 year of MI

30-08-2023 Myocardial Infarction News

In the Netherlands, only a very small proportion of patients start a PCSK9 inhibitor within 365 days of myocardial infarction. 

Awareness about CTEPH after acute pulmonary embolism still low

30-08-2023 Pulmonary Hypertension News

The low incidence of chronic thromboembolic pulmonary hypertension (CTEPH) after acute pulmonary embolism, in a German real-world cohort, suggests that there is low awareness around this syndrome. There also seems to be a lack of protocols for systematic follow-up for people who have had an acute PE.

26-08-2023 Myocardial Infarction News

FIRE trial supports complete revascularization for older MI patients

Physiology-guided complete revascularization can be considered for older patients with myocardial infarction and multivessel disease.

Noninferiority of immediate vs staged multivessel PCI shown in STEMI patients

28-08-2023 Myocardial Infarction News

Immediate multivessel PCI is noninferior to a staged approach in patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease.

Catheter ablation shows promise in end-stage heart failure with AF

27-08-2023 Heart Failure News

Results of a single-center trial suggest that patients with end-stage heart failure and symptomatic atrial fibrillation could benefit from catheter ablation.

No reduction in mortality with ECLS for infarct-related cardiogenic shock

27-08-2023 Myocardial Infarction News

The use of extracorporeal life support alongside medical therapy does not mitigate the risk for 30-day mortality in patients with acute myocardial infarction complicated by cardiogenic shock.

Oral anticoagulation not recommended for people with atrial high-rate episodes

26-08-2023 Cardiac Arrhythmia News

Anticoagulation with edoxaban does not reduce the risk for stroke and increases the incidence of bleeding in individuals with atrial high-rate episodes.

26-08-2023 Cardiac Arrhythmia News

Colchicine for reducing complications after major thoracic surgery

Treatment with colchicine did not significantly reduce the incidence of clinically important AF or myocardial injury after noncardiac thoracic surgery in the COP-AF study.

Stay up to date with more from Springer Medicine

Episode 3: Unravelling resistant hypertension

Why is it so difficult to diagnose and manage?

Resistant hypertension is a difficult to treat and often misunderstood phenomenon that continues to frustrate cardiologists. 

In this episode, Professors Morris Brown and Bryan Williams debate the causes of resistant hypertension and explore novel treatment options.

Prof. Morris Brown
Prof. Bryan Williams

Keynote webinar | Spotlight on cardio-oncology

Webinar | 16-05-2023 | 17:30 (CEST)

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
Developed by: Springer Medicine

Understanding obesity and atrial fibrillation

Open Access Obesity Review

Update on the epidemiology of obesity and atrial fibrillation, the mechanisms by which obesity triggers atrial fibrillation, and how the prognosis of atrial fibrillation can be improved by weight loss and risk factor control.

Further Reading

Assessment of atherosclerotic plaque burden: comparison of AI-QCT versus SIS, CAC, visual and CAD-RADS stenosis categories

Open Access Arterial Occlusive Disease Original Paper

This study assesses the agreement of Artificial Intelligence-Quantitative Computed Tomography (AI-QCT) with qualitative approaches to atherosclerotic disease burden codified in the multisociety 2022 CAD-RADS 2.0 Expert Consensus. 105 patients who …

Pressure waveform analysis for occlusion assessment significantly reduces contrast medium use in cryoballoon pulmonary vein isolation

Open Access Atrial Fibrillation ORIGINAL RESEARCH

Pulmonary vein isolation (PVI) represents the cornerstone of atrial fibrillation (AF) ablation today [ 1 ]. Cryoballoon-guided PVI (CB-PVI) has emerged a well-established ablation approach for safe and successful AF ablation and has been shown to …

Intravascular Imaging-Guided Versus Coronary Angiography-Guided Complex PCI: A Meta-analysis of Randomized Controlled Trials

Open Access Angiography Original Research

Despite evolutions in the development of drug-eluting stents (DES) and technical advances in equipment, percutaneous coronary intervention (PCI) for complex coronary anatomy continues to pose a significant challenge. According to the American …

PLD2 deletion ameliorates sepsis-induced cardiomyopathy by suppressing cardiomyocyte pyroptosis via the NLRP3/caspase 1/GSDMD pathway

Open Access Septicemia Original Research Paper

Despite improvements in critical care, sepsis affects more than 50 million individuals and accounts for 11 million deaths annually, making it a leading causes of death worldwide [ 1 , 2 ]. Most patients with sepsis have abnormal cardiac function …