ESC Congress 2023

Long-term mavacamten helps patients with symptomatic obstructive hypertrophic cardiomyopathy avoid septal reduction therapy, but may be linked to left ventricular systolic dysfunction.

Is too much atrial pacing associated with atrial fibrillation? The DANPACE II study argues it isn't.

Should loop diuretics be dosed in acute heart failure based on urinary sodium levels? The PUSH-AHF study has investigated this and provides interesting results.

Randomized trial findings show no survival advantage for expedited transfer to a specialist cardiac center for non-ST elevation out-of-hospital cardiac arrest.

Those with low levels of physical activity during childhood and adolescence may be creating an environment susceptible to heart attack and stroke later in life. 

Treatment with acoramidis in people with transthyretin-mediated amyloidosis yielded a significant reduction in all-cause mortality, cardiovascular hospitalizations, and an improvement in NT-proBNP.

Patients with congestive heart failure who face food insecurity in daily life have been found to have a higher mean BMI and lower albumin levels than those who are food secure.

Alirocumab every 2 or 4 weeks is a safe and effective treatment in children and adolescents with heterozygous familial hypercholesterolemia inadequately controlled with statins.

Icosapent-ethyl lowers the number of major adverse cardiovascular events in patients with atherosclerotic cardiovascular disease and elevated triglyceride levels.

Cancer patients treated with immune checkpoint inhibitors have an increased risk of major adverse cardiovascular events if they have a history of atherosclerotic cardiovascular disease or hypertension.

A comprehensive analysis shows that people who consume the most ultra-processed foods have a 24% higher risk of heart attack or stroke.

The ONCO DVT trial supports extended anticoagulation with edoxaban for cancer patients with isolated distal deep vein thrombosis.

A focused update of the ESC's heart failure guidelines will embed the results of major new studies into current practice.

Serum lipoprotein (a) concentrations appear to be a risk factor for bioprosthetic aortic valve degeneration. The next step in investigating the role of lipoprotein (a) would be whether lowering it could delay bioprosthetic valve degradation.

In the Netherlands, only a very small proportion of patients start a PCSK9 inhibitor within 365 days of myocardial infarction. 

The low incidence of chronic thromboembolic pulmonary hypertension (CTEPH) after acute pulmonary embolism, in a German real-world cohort, suggests that there is low awareness around this syndrome. There also seems to be a lack of protocols for systematic follow-up for people who have had an acute PE.

Immediate multivessel PCI is noninferior to a staged approach in patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease.

Results of a single-center trial suggest that patients with end-stage heart failure and symptomatic atrial fibrillation could benefit from catheter ablation.

The use of extracorporeal life support alongside medical therapy does not mitigate the risk for 30-day mortality in patients with acute myocardial infarction complicated by cardiogenic shock.

Anticoagulation with edoxaban does not reduce the risk for stroke and increases the incidence of bleeding in individuals with atrial high-rate episodes.

An increasingly large proportion of patients presenting with non-ST-elevation myocardial infarction (NSTEMI) are elderly. According to the European Society of Cardiology (ESC) guidelines on the management of acute coronary syndromes (ACS) in …

Evidence suggests that chronic venous disease (CVD) may be a cardiovascular disorder, as patients with CVD are prone to developing arterial (atherosclerosis) and venous (thromboembolism) diseases. This may be partly explained by shared risk …

To investigate the correlation the correlation between residual cholesterol (RC) and increased carotid intima-media thickness(cIMT) in non-diabetic individuals. This study included 1786 non-diabetic individuals who underwent carotid ultrasound. RC …

Acute coronary syndrome (ACS), a thrombotic, dramatic, and life-threatening complication of atherosclerosis, remains one of the leading causes of death [ 1 ], although substantial progress has been made in the diagnosis and treatment of this …