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Long-COVID Syndrome 

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  1. Open Access 16-04-2024 | Long-COVID Syndrome | Online First

    Cluster analysis of long COVID symptoms for deciphering a syndrome and its long-term consequence

    The long-term symptoms of COVID-19 are the subject of public and scientific discussions. Understanding how those long COVID symptoms co-occur in clusters of syndromes may indicate the pathogenic mechanisms of long COVID. Our study objective was to …

  2. Open Access 19-02-2024 | Echocardiography | OriginalPaper

    Longitudinal Cardiac Evaluation of Children with Multisystem Inflammatory Syndrome (MIS-C) Following COVID-19 by Conventional and Speckle-Tracking Echocardiography

    Multisystem inflammatory syndrome in children (MIS-C), is a rare but severe, hyperinflammatory complication of COVID-19, in which cardiovascular abnormalities are frequently detected. In this prospective study, we describe the echocardiographic …

  3. Open Access 01-12-2024 | Post-COVID Syndrome | OriginalPaper

    Longitudinal course and predictors of health-related quality of life, mental health, and fatigue, in non-hospitalized individuals with or without post COVID-19 syndrome

    A considerable proportion of patients infected with the coronavirus SARS-CoV-2 reports persisting symptoms such as fatigue, dyspnea, and cognitive problems, for weeks or months after the acute coronavirus disease 2019 (COVID-19) [ 1 – 4 ]. This …

  4. 22-03-2024 | SARS-CoV-2 | Online First

    Should we be afraid of long-term cardiac consequences in children with multisystem inflammatory syndrome? Experience from subsequent waves of COVID-19

    The purpose of the study was to assess and compare short- and long-term cardiac complications of the multisystem inflammatory syndrome in children (MIS-C) by predominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants …

  5. Open Access 01-12-2024 | OriginalPaper

    The global prevalence of depression, anxiety, and sleep disorder among patients coping with Post COVID-19 syndrome (long COVID): a systematic review and meta-analysis

    The ongoing COVID-19 pandemic has precipitated a worldwide health catastrophe, impacting not only the physical health of those infected but also their emotional stability [ 1 ]. Post-COVID-19 syndrome, which pertains to the persistence of symptoms …

  6. Open Access 01-12-2024 | Long-COVID Syndrome | OriginalPaper

    The demographic, laboratory and genetic factors associated with long Covid-19 syndrome: a case–control study

    Long Covid-19 syndrome (LCS) manifests with a wide range of clinical symptoms, yet the factors associated with LCS remain poorly understood. The current study aimed to investigate the relationships that demographic characteristics, clinical …

  7. Open Access 29-02-2024 | COVID-19 | Online First

    Health-Related Quality of Life for Patients with Post-Acute COVID-19 Syndrome: Identification of Symptom Clusters and Predictors of Long-Term Outcomes

    Following COVID-19 infection, as many as a third to a half of patients are left with long-term symptoms, known as post-acute sequelae of SARS-CoV-2 infection (PASC). 1 – 4 PASC has been defined as a condition where symptoms continue for more than …

  8. Open Access 03-01-2024 | Long-COVID Syndrome | Online First

    Conceptual foundations of acetylcarnitine supplementation in neuropsychiatric long COVID syndrome: a narrative review

    Post-acute sequelae of COVID-19 can present as multi-organ pathology, with neuropsychiatric symptoms being the most common symptom complex, characterizing long COVID as a syndrome with a significant disease burden for affected individuals. Several …

  9. 10-11-2023 | Long-COVID Syndrome | ReviewPaper

    Autonomic Manifestations of Long-COVID Syndrome

    The COVID-19 pandemic has had a devastating impact on the health and economy of individuals all over the world. As of October 2023, there have been >770 million cases and almost 7 million deaths due to the novel coronavirus [ 1 ]. While the deaths …

  10. 20-01-2024 | COVID-19 | Online First

    Long-Term Outcomes of Survivors of COVID-19 with Moderate to Severe Infection and Children with Multisystem Inflammatory Syndrome or MIS-C

    The study aims to evaluate the long-term outcomes − functional, pulmonary and non-pulmonary (other organs) − in children hospitalized with COVID-19 infection or with Multisystem inflammatory syndrome (MIS-C) after 1–2 y of discharge. All children …

  11. Open Access 16-04-2023 | Long-COVID Syndrome | Letter

    Unique immune and inflammatory cytokine profiles may define long COVID syndrome

    After initial SARS-CoV-2 infection, an estimated 5–10% of individuals develop persistent symptoms [ 1 ]. The World Health Organization defines “long COVID” as symptoms lasting for at least 2 months, at least 3 months after the onset of COVID-19 …

  12. Open Access 01-12-2023 | Long-COVID Syndrome | ReviewPaper

    A scoping review of ‘Pacing’ for management of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): lessons learned for the long COVID pandemic

  13. Open Access 03-02-2023 | Long-COVID Syndrome | OriginalPaper

    Not myopathic, but autonomic changes in patients with long-COVID syndrome: a case series

    It is well known that SARS-CoV-2 leads to several neurological manifestations, including large-vessel strokes, seizures at onset, muscle pain, and para-infectious neuropathies. The neurological involvement is due to different mechanisms of action …

  14. Open Access 17-07-2023 | Long-COVID Syndrome | ReviewPaper

    Multisystem inflammatory syndrome in children (MIS-C): Implications for long COVID

    The COVID-19 pandemic caused by the coronavirus 2 of the severe acute respiratory syndrome (SARS-CoV-2) has significantly affected people around the world, leading to substantial morbidity and mortality. Although the pandemic has affected people …

  15. Open Access 01-12-2023 | COVID-19 | OriginalPaper

    Association of adiposity and its changes over time with COVID-19 risk in older adults with overweight/obesity and metabolic syndrome: a longitudinal evaluation in the PREDIMED-Plus cohort

    Coronavirus disease-2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) infection, which emerged as a global pandemic towards the end of 2019 [ 1 , 2 ]. SARS-CoV2 had a pandemic potential, unlike the …

  16. 01-12-2022 | Sufentanil

    Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndrome

    The coronavirus disease 2019 (COVID-19) pandemic has incepted a surge of mechanically ventilated patients suffering from acute respiratory distress syndrome (ARDS), who have demonstrated to be characteristically complex to sedate and require high …

  17. Open Access 01-12-2022 | Insomnia | OriginalPaper

    Central hypersomnia and chronic insomnia: expanding the spectrum of sleep disorders in long COVID syndrome - a prospective cohort study

    The new coronavirus SARS-CoV-2 rapidly spread around the world, turning into a pandemic [ 1 , 2 ]. SARS-CoV-2 enters cells through interaction with angiotensin converting enzyme-2 (ACE2) receptors present in many cell types, including nasal mucosa …

  18. Open Access 01-12-2022 | Long-COVID Syndrome | OriginalPaper

    Trigger point injections and dry needling can be effective in treating long COVID syndrome-related myalgia: a case report

    Myofascial pain (MP) is a complex health condition that affects many patients, and is thought to occur from muscle overuse, trauma, and psychological stress [ 1 ]. The loci of the pain are termed “trigger points,” which are tender spots in a taut …

  19. Open Access 12-05-2022 | Long-COVID Syndrome | OriginalPaper

    Hypoechogenicity of brainstem raphe in long-COVID syndrome–less common but independently associated with depressive symptoms: a cross-sectional study

    Being initially reported as a pure respiratory infection, it became quickly apparent that Coronavirus disease 2019 (COVID-19) is a multi-organ disease, giving rise to cardiovascular, renal, gastrointestinal, hepatic, hematological, metabolic, and …

  20. Open Access 14-02-2023 | Long-COVID Syndrome | OriginalPaper

    Left atrial longitudinal strain analysis in long Covid-19 syndrome

    It is known that during the active course of Coronavirus disease 2019 (COVID-19), myocardial injury has an established pathological base, while its myocardial injury post-recovery is still obscured.The aim of this study was to evaluate the …

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