Learn about Fabry disease, a rare disease that can have renal, cardiovascular, neurological, cutaneous, and ophthalmic manifestations. Discover the ways in which it may be possible to personalize treatment.
The risks of ischemic and hemorrhagicstroke and poor neurological outcomes after stroke are increased in people with type 2 diabetes. Explore how to manage the hyperacute stroke stage and CV disease prevention.
Guidelines from the Pediatric Renal Nutrition Taskforce advise on assessing and managing vitamin deficiency or excess in children with CKD stages 2–5, on dialysis and post-transplantation.
New computerized clinical decision support system could help primary care physicians improve hypertension control in people with chronic kidney disease.
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Kidney injury is a known side-effect of using adalimumab to treat inflammatory bowel diseases, but has rarely been seen in children. Timely withdrawal can significantly reduce kidney damage but it is irreversible in some cases.
Changing to a ciclosporin-based regimen resolved the signs and symptoms of hepatitis in a patient who presented with icterus, weakness, and lethargy two weeks after kidney transplantation and initiation of tacrolimus.
A case of treatment-resistant hyperparathyroidism with severe complications in a long-term kidney dialysis patient, who presented with an atypically located adenoma that required comprehensive surgical intervention.
The retroperitoneum, a confined complex intra-abdominal space with defined anatomic fascial layers, can host a variety of pathologic processes. Certain pathologies originate in the retroperitoneum, while for others, it serves as a route for …
Children with chronic kidney disease (CKD) can have an inherent vulnerability to dehydration. Younger children are unable to freely access water, and CKD aetiology and stage can associate with reduced kidney concentrating capacity, which can also …
Familial primary hyperparathyroidism (PHPT) represents approximately 10–15% of all cases of PHPT [ 1 ]. The most common heritable syndromic form is the multiple endocrine neoplasia (MEN) type 1 (MEN1) syndrome, which affects 2% to 4% of patients …
Inflammation plays a crucial role in the pathophysiology of various kidney diseases. Kidney perivascular cells (pericytes/fibroblasts) are responsible for producing proinflammatory molecules, promoting immune cell infiltration, and enhancing …
Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.
This program is not available to users in the UK and US.
An independent educational program featuring simulated patient consultations. Make knowledge-based decisions on diagnosis and management of CKD with and without co-morbidities, and learn from experts Kevin Fernando and David Wheeler.
Membranoproliferative glomerulonephritis (MPGN) is a glomerular injury characterized by pathological findings of mesangial interposition and double contours of the capillary wall [ 1 ]. Historically, MPGN was morphologically classified into three …
The gold standard for diagnosing vesicoureteral reflux (VUR) is voiding cystourethrography (VCUG). This imaging technique allows an accurate VUR grading and detection of urethral abnormalities in male patients [ 1 ]. However, VCUG exposes children …
Chronic kidney disease (CKD) is a disease for which continuous multidisciplinary care, including nephrologists, nurses, pharmacists, and dietitians, is important. Multidisciplinary care for CKD has been reported to prevent deterioration of renal …
Chronic kidney disease (CKD) represents a substantial clinical and public health challenge due to its escalating incidence and prevalence rates. It stands as a prominent contributor to both morbidity and mortality associated with end-stage renal …
