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Internal Medicine Nephrology

Nephrology

28-03-2024 Chronic Kidney Disease News

Computerized alerts improve BP management in CKD

New computerized clinical decision support system could help primary care physicians improve hypertension control in people with chronic kidney disease.

High risk of adverse kidney events in young people on CKRT

25-03-2024 Pediatric Nephrology News

Major adverse kidney events occur within 90 days in nearly two thirds of children, adolescents, and young adults after initiation of continuous kidney replacement therapy.

Adalimumab causes kidney injury in pediatric Crohn’s disease

Kidney injury is a known side-effect of using adalimumab to treat inflammatory bowel diseases, but has rarely been seen in children. Timely withdrawal can significantly reduce kidney damage but it is irreversible in some cases.

Potential new treatment for complicated UTIs

Cefepime–taniborbactam combination treatment might be a better option than meropenem for complicated urinary tract infections and acute pyelonephritis.

Nephroprotective effects of incretin-based therapies

Open Access Diabetic Nephropathy Review

Cardiovascular outcome trials indicate that incretin-based therapies have renal benefits beyond their glucose-lowering efficacy. But what is the evidence regarding the nephroprotective effects of these anti-diabetes compounds?

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Adalimumab causes kidney injury in pediatric Crohn’s disease

Kidney injury is a known side-effect of using adalimumab to treat inflammatory bowel diseases, but has rarely been seen in children. Timely withdrawal can significantly reduce kidney damage but it is irreversible in some cases.

Cholestatic hepatotoxicity after kidney transplantation

Open Access Toxic Hepatitis Case Study

Changing to a ciclosporin-based regimen resolved the signs and symptoms of hepatitis in a patient who presented with icterus, weakness, and lethargy two weeks after kidney transplantation and initiation of tacrolimus.

Refractory secondary hyperparathyroidism presenting with retro-orbital brown tumor

Open Access Hyperparathyroidism Case Study

A case of treatment-resistant hyperparathyroidism with severe complications in a long-term kidney dialysis patient, who presented with an atypically located adenoma that required comprehensive surgical intervention.

Current Reviews

Targeting inflammation in perivascular cells and neuroimmune interactions for treating kidney disease

Open Access Vagus Nerve Stimulation Invited review article

Inflammation plays a crucial role in the pathophysiology of various kidney diseases. Kidney perivascular cells (pericytes/fibroblasts) are responsible for producing proinflammatory molecules, promoting immune cell infiltration, and enhancing …

Functional magnetic resonance imaging for staging chronic kidney disease: a systematic review and meta-analysis

Chronic Kidney Disease Nephrology - Review

Chronic kidney disease (CKD) is a prevalent condition worldwide. It seriously threatens human health because of the high morbidity and mortality rates and a rapidly increasing incidence of early symptoms that may not be obvious until the condition …

Ablation of Kidney Tumors in Patients with Substantial Kidney Impairment: Current Status

Current guidelines advocate surgical intervention, notably partial nephrectomy (PN), as the standard therapy for small and localized renal cell carcinoma (RCC) [ 1 – 6 ]. However, patients with such RCC are not always surgical candidates because of …

Vodcasts | Case Scenarios (Link opens in a new window)

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

eLearning | Infographics (Link opens in a new window)

An independent educational program featuring simulated patient consultations. Make knowledge-based decisions on diagnosis and management of CKD with and without co-morbidities, and learn from experts Kevin Fernando and David Wheeler.

Supported by:
  • AstraZeneca
Developed by: Springer Healthcare IME

Further Reading

Targeting inflammation in perivascular cells and neuroimmune interactions for treating kidney disease

Open Access Vagus Nerve Stimulation Invited review article

Inflammation plays a crucial role in the pathophysiology of various kidney diseases. Kidney perivascular cells (pericytes/fibroblasts) are responsible for producing proinflammatory molecules, promoting immune cell infiltration, and enhancing …

Hypertension and diabetes, but not leptin and adiponectin, mediate the relationship between body fat and chronic kidney disease

Open Access Chronic Kidney Disease Original Article

Globally, the prevalence of obesity (body mass index (BMI) ≥ 30 kg/m 2 ) has tripled since 1975 [ 1 , 2 ]. Approximately 604 million adults suffered from obesity worldwide in 2015 [ 3 ]. Obesity is related with an increased risk of hypertension and …

Early diagnosis of solitary functioning kidney: comparing the prognosis of kidney agenesis and multicystic dysplastic kidney

Open Access Vesicorenal Reflux Original Article

In children, 30–50% of chronic renal failure cases are caused by congenital anomalies of the kidneys and urinary tract (CAKUT) [ 1 , 2 ]. The risk of kidney damage is mainly present in children with bilateral kidney anomalies or solitary …

Diagnostic magnetic resonance imaging characteristics of congenital mesoblastic nephroma: a retrospective multi-center International Society of Pediatric Oncology-Renal Tumor Study Group (SIOP-RTSG) radiology panel study

Open Access Magnetic Resonance Imaging Original Article

Congenital mesoblastic nephroma accounts for only 2–5% of all pediatric renal tumors, whereas it is the most common solid renal tumor in neonates [ 1 – 5 ]. Approximately 75% of all cases are diagnosed in the first 6 months of life [ 5 ].