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Antiepileptic strategies for patients with brain tumors

Epilepsy due to primary or metastatic brain tumors accounts for 6–10% of all cases of epilepsy. Levetiracetam monotherapy is the initial treatment of choice, but other pharmacologic and nonpharmacologic options are also available.

Corticosteroids for hydrocephalus in neurosarcoidosis

Open Access Hydrocephalus Case Study

Hydrocephalus is a rare complication of neurosarcoidosis, usually requiring prompt high-dose IV corticosteroids and neurosurgical treatment. Neurosurgery can have severe complications, but select cases may be eligible for drug treatment only.

Rescue therapies for seizure clusters

Open Access Epilepsy Review

Benzodiazepines are effective rescue therapies for seizure clusters in patients with epilepsy, but are underused. Intranasal sprays now offer more practical alternatives to rectal diazepam gel.

Endovascular thrombectomy shows long-term benefits for large ischemic stroke

26-02-2024 Ischemic Stroke News

SELECT2 trial finds that adding EVT to best medical care improves functional outcomes at 1 year in patients with large ischemic stroke. 

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Corticosteroids for hydrocephalus in neurosarcoidosis

Open Access Hydrocephalus Case Study

Hydrocephalus is a rare complication of neurosarcoidosis, usually requiring prompt high-dose IV corticosteroids and neurosurgical treatment. Neurosurgery can have severe complications, but select cases may be eligible for drug treatment only.

Cerebral air embolism following necrotizing pneumonia

Open Access Cerebral Air Embolism Case Study

In abrupt onset of cognitive impairment, seizures, or focal neurological deficits, particularly cases with underlying lesions or following procedures carrying a risk of air induction, cerebral air embolism could be the culprit.

Huge osteoma in the frontoparietal bone

Open Access osteoma Case Study

Osteomas are benign tumors containing cortical and cancellous bone tissues. 18 years after a head trauma, a huge osteoma was discovered following a month of headaches, syncope episodes, and blurred vision.

Current Reviews

Eplontersen: First Approval

Polyneuropathy AdisInsight Report

Eplontersen (Wainua™) is a ligand-conjugated antisense oligonucleotide directed to TTR, which is being developed by Ionis Pharmaceuticals and AstraZeneca for the treatment of TTR-mediated amyloidosis (ATTR). Eplontersen, which is targeted to the …

Male sexual and reproductive health in multiple sclerosis: a scoping review

Open Access Multiple Sclerosis Review

Multiple sclerosis (MS) is a chronic neuroinflammatory disease that adversely affects physical and mental health and can lead to social dissatisfaction [ 1 , 2 ]. There are 2.8 million people living with MS worldwide [ 3 ]. Newer high-efficacy …

The Impact of Aging on Multiple Sclerosis

Multiple sclerosis (MS) is a chronic, immune-mediated demyelinating disorder of the central nervous system. Disease presentation and clinical course are variable and significantly influenced by an individual’s age. The average age of onset is …

Recent Advances in Clinical Trials in Multiple System Atrophy

Multiple system atrophy (MSA) is a rare neurodegenerative disease characterized by parkinsonism, cerebellar symptoms, and autonomic dysfunction to various extents [ 1 ]. The neuropathological hallmark is the accumulation of alpha-synuclein (aSyn) …

Webcast | eLearning | Infographic (Link opens in a new window)

PET biomarkers are fast becoming critical in the new era of disease modification for Alzheimer’s disease. Techniques around amyloid and tau require the expertise of nuclear medicine and radiology physicians to investigate and interpret PET scans in clinical settings. This program examines current and emerging biomarkers and assists in identifying patterns from different PET tracers in an interactive perceptual learning environment.

Supported by:
  • Lilly
Developed by: Springer Healthcare IME

eLearning | Infographic (Link opens in a new window)

Animated, interactive expert-led website focusing on  neuroinflammation and its role in the development of Alzheimer’s disease.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk Health Care AG
Developed by: Springer Healthcare IME

Webcast | Patient Cases (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)

Multiformat program improving awareness, diagnosis and management of patients with adult growth hormone deficiency.

Supported by:
  • Novo Nordisk Health Care AG
Developed by: Springer Healthcare IME

Further Reading

Vocabulary knowledge as a reliable proxy of cognitive reserve in multiple sclerosis: a validation study

Open Access Multiple Sclerosis Original Article

Cognitive changes in multiple sclerosis (MS) are estimated to affect 40-70% of patients because of chronic and multifocal MS-related central nervous system (CNS) damage [ 1 ]. Cognitive impairment is one of the most disabling manifestations in …

Real-World Retrospective Analysis of Alemtuzumab Outcomes in Relapsing-Remitting Multiple Sclerosis: The LEMCAM Study

Open Access Alemtuzumab Original Research

The current landscape of new disease-modifying therapies (DMTs) has improved the course of patients with multiple sclerosis (MS) by reducing relapses and disability progression and improving health-related quality of life. These advances enable …

Comparison between the 0- and 30-s balloon dilation time in percutaneous transluminal angioplasty for restenosed arteriovenous fistula among hemodialysis patients: a multicenter, prospective, randomized trial (CARP study)

Open Access Arteriovenous Fistula Original article

Chronic kidney disease (CKD) is a well-recognized global health concern, affecting roughly 800 million individuals worldwide [ 1 ]. As CKD progresses, renal function declines, and many patients eventually develop end-stage kidney disease [ 2 ] …

Anatomical correlates of apathy and impulsivity co-occurrence in early Parkinson’s disease

Open Access Parkinson's Disease Original Research

Neuropsychiatric manifestations of Parkinson’s disease (PD) include a variety of hyperactive and hypoactive behaviors [ 1 ]. One of the most prevalent hyper-active behaviors in PD is impulse control disorders (ICDs), characterized by the inability …

Related topics

26-02-2024 Ischemic Stroke News

Endovascular thrombectomy shows long-term benefits for large ischemic stroke

SELECT2 trial finds that adding EVT to best medical care improves functional outcomes at 1 year in patients with large ischemic stroke. 

Read more
Open Access Medical Side Effect Case Study

Unique presentation of memantine overdose

Hypertensive urgency and echolalia were the most striking symptoms of memantine overdose in an elderly man with mild dementia and hypertension. Early medication review with caregivers of people with dementia is key.

Read more

Antiepileptic strategies for patients with brain tumors

Epilepsy due to primary or metastatic brain tumors accounts for 6–10% of all cases of epilepsy. Levetiracetam monotherapy is the initial treatment of choice, but other pharmacologic and nonpharmacologic options are also available.

Read more
Open Access Trigeminal Neuralgia Review

Managing trigeminal postherpetic neuralgia

Trigeminal postherpetic neuralgia is a persistent and debilitating neuropathic pain condition, caused by reactivation of varicella zoster virus. This review explores its clinical characteristics, pathophysiological underpinnings, and existing and potential therapies.

Read more

Antiepileptic strategies for patients with brain tumors

Epilepsy due to primary or metastatic brain tumors accounts for 6–10% of all cases of epilepsy. Levetiracetam monotherapy is the initial treatment of choice, but other pharmacologic and nonpharmacologic options are also available.

Read more

The gut microbiota, gut–brain axis, and type 2 diabetes

The gut microbiota and host communicate bidirectionally along the gut–brain axis to regulate glucose homeostasis, and evidence supports a role for dysbiosis of the gut microbiota in the development of type 2 diabetes.

Read more