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An overview of validated screening tools to systematically characterize symptoms and identify comorbidities in children and adolescents with autonomic dysfunction and orthostatic intolerance.

Dabrafenib plus trametinib is superior to standard chemotherapy in untreated pediatric patients with low-grade glioma carrying BRAF V600 mutations.

The Optimal-BP trial results show that early, intensive blood pressure lowering should be avoided following endovascular thrombectomy for acute ischemic stroke.

Primary bilateral macronodular adrenal hyperplasia with cryptococcal meningitis that developed after laparoscopic left adrenalectomy. Outcomes may be improved by treating cryptococcus infection before removing the adrenals.

Current Reviews

Episode 5: Next-generation sequencing

Emerging biomarkers in thyroid and non-small cell lung cancers

Next-generation sequencing is a powerful tool that can identify mutations or fusions in a wide range of cancers, enabling physicians to provide targeted therapy to patients and improve outcomes. In this podcast, Professor Andrew Beggs discusses practical aspects of this technique from the clinical viewpoint.

This content is intended only for healthcare providers and was made possible by educational funding provided by Illumina, Inc., and Eli Lilly and Company.

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Clinical course and autopsy findings from two patients treated with aducanumab for Alzheimer's disease, shedding light on the time course of amyloid lowering and the potential impact of co-pathology on clinical response.

Primary bilateral macronodular adrenal hyperplasia with cryptococcal meningitis that developed after laparoscopic left adrenalectomy. Outcomes may be improved by treating cryptococcus infection before removing the adrenals.

Intracranial GCTs developed occult extracranial malignancy with negative tumor markers, indicating that tumor marker monitoring may need to be combined with regular follow-up abdominal imaging for early detection.

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PET biomarkers are fast becoming critical in the new era of disease modification for Alzheimer’s disease. Techniques around amyloid and tau require the expertise of nuclear medicine and radiology physicians to investigate and interpret PET scans in clinical settings. This program examines current and emerging biomarkers and assists in identifying patterns from different PET tracers in an interactive perceptual learning environment.

Neuroinflammation affects the risk, onset, and progression of Alzheimer’s disease. 

Improve your understanding of the role of neuroinflammation in the development of AD in a new animated website, which takes you through the complex mechanisms of pathology, including the genetic, exposome, and microbiome risk factors that contribute to a neuroinflammatory response. 

Supplemented by expert commentary from Michael Heneka.

This program is not available to users in the UK and US.

Multiformat program improving awareness, diagnosis and management of patients with adult growth hormone deficiency.

CME: 1.5 AMA PRA Category 1 Credit(s)™

Further Reading

Related topics

Rapid genome sequencing in infants with new-onset epilepsy is effective for early genetic diagnoses and prompt initiation of targeted treatments.

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Primary bilateral macronodular adrenal hyperplasia with cryptococcal meningitis that developed after laparoscopic left adrenalectomy. Outcomes may be improved by treating cryptococcus infection before removing the adrenals.

Read more

An overview of validated screening tools to systematically characterize symptoms and identify comorbidities in children and adolescents with autonomic dysfunction and orthostatic intolerance.

Read more