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Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on adolescent vaping

Growing numbers of young people are using e-cigarettes, despite warnings of respiratory effects and addiction. How can doctors tackle the epidemic, and what health effects should you prepare to manage in your clinics?

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Neurology

Two different drug classes promising for myasthenia gravis

Nipocalimab, a neonatal Fc receptor inhibitor, and satralizumab, a monoclonal antibody targeting IL-6, have each shown positive clinical outcomes in treating myasthenia gravis.

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Editor's Choice

How to diagnose rheumatoid meningitis

RM is a rare cause of chronic meningitis. Diagnosis is challenging due to its varied clinical manifestations and the absence of recognized criteria. This case illustrates what you need to look for.

Vaccines for neurological disease

How far off are vaccine-based approaches to prevent and modify the progression of diseases such as Alzheimer’s, Parkinson’s, multiple sclerosis, Huntington’s, ALS, and CJD?

Neuroblastoma mimicking Bell’s palsy

A high degree of suspicion is required to identify neuroblastoma presenting in an atypical manner. Here the child initially exhibited just left-sided facial paralysis, mimicking Bell’s palsy.

Trigeminal neuralgia: will surgery help?

TN is highly heterogeneous with a wide choice of successful treatment options, but predicting which patients will respond to different treatments remains challenging.

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Episode 14: Diagnostic criteria for AD

Can we define Alzheimer's disease as a purely biological entity?

Blood-based biomarkers are set to make biological assessment of Alzheimer's disease much quicker and more accessible than has been possible with imaging and CSF biomarkers. Does this mean the disease now be defined as a purely biological entity? 

Dr. Nicolas Villain outlines why it is still so important to consider both clinical symptoms and biological findings when making a diagnosis. 

Dr. Nicolas Villain
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Latest News

Two different drug classes promising for myasthenia gravis

Apixaban may prevent covert infarcts after cryptogenic ischemic stroke

Small reduction in apathy with intranasal oxytocin in FTD

Apixaban benefit over aspirin greater in atrial fibrillation patients with stroke history

Limited intracranial response to ICIs after anti-PD-1 therapy

MS increases mental illness risk in perinatal period

Case Studies

How to diagnose rheumatoid meningitis

RM is a rare cause of chronic meningitis. Diagnosis is challenging due to its varied clinical manifestations and the absence of recognized criteria. This case illustrates what you need to look for.

Neuroblastoma mimicking Bell’s palsy

A high degree of suspicion is required to identify neuroblastoma presenting in an atypical manner. Here the child initially exhibited just left-sided facial paralysis, mimicking Bell’s palsy.

Gouty lumbar spinal stenosis

  • Open Access
  • Gout
  • Case Study

An unusual case of lumbar spinal stenosis caused by gouty tophi in a 26-year-old man. Physicians should be alert to the possibility of spinal gout in patients who present with back pain.

Keynote series | Spotlight on menopause

Menopause can have a significant impact on the body, with effects ranging beyond the endocrine and reproductive systems. Learn about the systemic effects of menopause, so you can help patients in your clinics through the transition.   

Prof. Martha Hickey
Dr. Claudia Barth
Dr. Samar El Khoudary
Developed by: Springer Medicine
Watch now

Current Reviews

Pharmaceutical considerations in treating neuropathic pain in athletes

Neuropathic pain is a complex and challenging condition that arises from abnormal processing of somatosensory information, often following nerve injury or dysfunction. Its diagnosis involves a detailed clinical history, sensory examination, and …

Pain and fatigue in Parkinson’s disease: advances in diagnosis and management

Non-motor symptoms affect over 90% of people with Parkinson’s disease at all stages, with pain and fatigue being among the most prevalent yet often neglected in clinical practice. Despite their significant impact, these symptoms are frequently …

Protein misfolding: understanding biology to classify and treat synucleinopathies

  • Open Access
  • Parkinson Disease
  • Neurology and Preclinical Neurological Studies - Review Article

Protein misfolding and aggregation is a major pathological hallmark in a variety of human conditions, including cancer, diabetes, and neurodegeneration. However, we still do not fully understand the role of protein accumulation in disease.

Exploring the interplay of glucose metabolism, insulin resistance, and neurodegenerative pathologies: insights from streptozotocin and hypoglycaemic in vitro models

  • Open Access
  • Alzheimer's Disease
  • Neurology and Preclinical Neurological Studies - Review Article

Neurodegenerative diseases raise public health concerns. Recent evidence indicates that Alzheimer’s disease (AD) sufferers will triple by 2050. The rising incidence of dementia diagnoses raises concerns about the socio-economical and emotional …

Keynote webinar | Spotlight on modern management of frailty

Frailty has a significant impact on health and wellbeing, especially in older adults. Our experts explain the factors that contribute to the development of frailty and how you can manage the condition and reduce the risk of disability, dependency, and mortality in your patients.

Prof. Alfonso Cruz-Jentoft
Prof. Barbara C. van Munster
Prof. Mirko Petrovic
Developed by: Springer Medicine
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CME & eLearning

Webcast (Link opens in a new window)

1.0 Interprofessional Continuing Education (IPCE) credit, 1.0 AAPA Category 1 CME credits

DMD remains a progressive incurable disease, but advances in patient-centered care and treatment for cardiopulmonary dysfunction have helped to increase life expectancy. This program equips multidisciplinary teams, including pediatric neurologists, pediatricians, pulmonologists, cardiologists, and endocrinologists, with key knowledge and skills to enhance care throughout the patient journey.

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME

Panel Discussions | Vodcasts | News (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)™

Emerging biomarkers and disease-modifying therapies for Alzheimer’s disease promise significant changes in how the condition is diagnosed and managed. Guide yourself through this transition with our education program, led by world renowned experts and covering the biggest international conferences.

This content is intended for healthcare professionals outside of the UK.

Supported by:
  • Lilly
Developed by: Springer Healthcare IME

Webinar (Link opens in a new window)

Interact with experts from established amyloidosis centers who can offer you specialized guidance to support your mission to set up a local center. Network with other HCPs in your locality to discuss region-specific challenges in establishing amyloidosis centers. 

Supported by:
  • AstraZeneca and Alexion
Developed by: Springer Healthcare IME

Most Viewed in Neurology

Cardiac rehabilitation in patients with frailty

SGLT2 inhibitor triggers metabolic encephalopathy

An Update on Emerging Regenerative Medicine Applications: The Use of Extracellular Vesicles and Exosomes for the Management of Chronic Pain

  • Osteoarthrosis
  • Alternative Treatments for Pain Medicine (C Robinson, Section Editor)

Does Long-Term Selection for Reactions to Humans Affect Decision-Making during Learning in Foxes?

  • Physiological Mechanisms of Behavior in Animals: Perception of External Stimuli, Motor Activity, and Learning and Memory

Autoimmune cerebellar ataxia associated with anti-SEZ6L2 antibody: report of three cases

Treatment Preferences of Physicians Treating Adult Patients with Attention-Deficit/Hyperactivity Disorder in the United States and Canada: A Discrete Choice Experiment

Neurology journals

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Further Reading

Radiomics for differentiating radiation-induced brain injury from recurrence in gliomas: systematic review, meta-analysis, and methodological quality evaluation using METRICS and RQS

  • Open Access
  • Glioma
  • Imaging Informatics and Artificial Intelligence

Gliomas encompass a broad spectrum of central nervous system tumors, classified by the World Health Organization (WHO) into grades 1 to 4 [ 1 , 2 ]. While high-grade gliomas (grades 3 and 4) are typically malignant and associated with high …

Pharmaceutical considerations in treating neuropathic pain in athletes

Neuropathic pain is a complex and challenging condition that arises from abnormal processing of somatosensory information, often following nerve injury or dysfunction. Its diagnosis involves a detailed clinical history, sensory examination, and …

The Effect of the Maxillary Sinus Volume on the Morphology and Angulation of the Infraorbital Canal in Relation to Age and Gender

Knowledge of the variable morphology and morphometric characteristics of the infraorbital canal (IOC) is essential for progress in planning of various midface, orbital, and periocular procedures including filler injections, fat grafting, lower …

Multi-parametric [18F]PI-2620 tau PET/MRI for the phenotyping of different Alzheimer’s disease variants

Alzheimer’s disease (AD) is a gradually progressive neurodegenerative disorder which is biologically characterized by the toxic accumulation of misfolded amyloid-β (amyloid plaques) and tau (neurofibrillary tangles) in cortical brain tissue …

Related topics

Noninvasive retinal imaging shows potential for evaluating stroke risk

Detailed analysis of retinal blood vessels using fundus photography may significantly improve stroke risk prediction.

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Doubt over efficacy of adjunctive thrombolytic for ischemic stroke

Cholesterol crystal embolization following alteplase for stroke

Recurrent strokes after TAVR in patient with BAV

Impact of DOACs on thrombolysis and thrombectomy in stroke

RCVS linked to methylphenidate

Vaccines for neurological disease

How far off are vaccine-based approaches to prevent and modify the progression of diseases such as Alzheimer’s, Parkinson’s, multiple sclerosis, Huntington’s, ALS, and CJD?

Read more

Small reduction in apathy with intranasal oxytocin in FTD

TAK-071 fails to improve gait variability in PD

Brain health, glycemic homeostasis, and type 2 diabetes

Taxi and ambulance drivers least likely to die from AD

What is the future for dementia with Lewy bodies?

Lead encephalopathy from chipped paint

Public health measures mean severe lead toxicity is rare, making its recognition and management challenging. This 4-year-old presented with refractory status epilepticus and severe microcytic anemia. How would you diagnose and treat her?

Read more

Advances in treating drug-resistant epilepsy

Bright future for vagus nerve stimulation

Evolving disease: viral to autoimmune encephalitis to MS

Cenobamate use before epilepsy surgery

Reducing risk of SUDEP

Neuromodulation for headache in pregnancy

Managing headache disorders during pregnancy is challenging due to a known risk of teratogenicity or unknown risks of drug therapies. Can neuromodulatory devices offer a safe and effective alternative?

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Migraine in men

Empty sella syndrome: an update

RCVS linked to methylphenidate

Combining treatments for migraine prophylaxis

Therapies for cluster headache

How to diagnose rheumatoid meningitis

RM is a rare cause of chronic meningitis. Diagnosis is challenging due to its varied clinical manifestations and the absence of recognized criteria. This case illustrates what you need to look for.

Read more

Can efgartigimod help treat anti-NMDAR encephalitis?

Neurological complications of long COVID

Immune response in TBI

Infective endocarditis with septic embolization in the brain

How do autoimmune neurological diseases affect sleep?

Empty sella syndrome: an update

Empty sella is generally an incidental radiological finding, but when endocrine, neurological, ophthalmological, or psychiatric symptoms occur empty sella syndrome must be promptly diagnosed.

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Primary vitreoretinal lymphoma mimics fungal endophthalmitis

Intracranial pressure crisis

Emerging therapies for brain metastases

Advances in primary CNS lymphoma

Updated guidelines for chemotherapy in glioma

Neuroblastoma mimicking Bell’s palsy

A high degree of suspicion is required to identify neuroblastoma presenting in an atypical manner. Here the child initially exhibited just left-sided facial paralysis, mimicking Bell’s palsy.

Read more

Trigeminal neuralgia: will surgery help?

Rapid progression of Guillain-Barré syndrome

Efgartigimod PH20 reduces risk for CIPD relapse

Peripheral nerve stimulation for neuropathic pain

Refsum disease revealed by dilated cardiomyopathy

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