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Dementia 

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  1. Open Access 01-12-2024 | Dementia | OriginalPaper

    Addition of inflammation-related biomarkers to the CAIDE model for risk prediction of all-cause dementia, Alzheimer’s disease and vascular dementia in a prospective study

    The number of dementia cases worldwide is continuously rising and is projected to double nearly every 20 years [ 1 ]. With the approval of Aduhelm , Leqembi, and Donanemab as the first effective treatments against Alzheimer’s disease (AD) by the …

  2. 01-04-2024 | News

    Methotrexate may reduce risk of dementia

  3. Open Access 01-12-2024 | Dementia | OriginalPaper

    Considering inequities in national dementia strategies: breadth, depth, and scope

    The World Health Organisation (WHO) has designated dementia as a public health priority that requires urgent public health advocacy and global policies to mitigate its massive burden on the individual, community, economy, and healthcare system [ 1 …

  4. Open Access 01-12-2024 | Dementia | OriginalPaper

    A qualitative study of informal caregiver perceptions of the benefits of an early dementia diagnosis

    It is estimated that there are 944,000 people with dementia in the United Kingdom (UK) [ 1 ] however, only two-thirds have received a formal diagnosis [ 2 ]. Previous and current dementia policies in the UK recommend not only increasing diagnosis …

  5. Open Access 01-12-2024 | Alzheimer's Disease | OriginalPaper

    Alteration of medial temporal lobe metabolism related to Alzheimer’s disease and dementia with lewy bodies

    Alzheimer’s disease (AD) and Lewy body disease (LBD) are the two most common neurodegenerative and pathological causes of dementia. Although mixed pathologies of AD and LBD are common in cognitively impaired patients on autopsy; [ 1 , 2 ] precise …

  6. Open Access 01-12-2024 | Dementia | OriginalPaper

    Determinants of hospital readmissions in older people with dementia: a narrative review

    Dementia is a known public health priority due to the increasing amount of people living with the condition worldwide and the subsequent demands placed on health and social care systems, the economy and society [ 1 ]. The World Alzheimer’s Report …

  7. Open Access 01-12-2024 | Dementia | OriginalPaper

    Association of midlife body-weight variability and cycles with earlier dementia onset: a nationwide cohort study

    Body weight (BW) varies throughout an individual’s life. With increased health awareness, people have tried to modify their lifestyles to prevent several diseases. Repeated attempts at lifestyle modification lead people to experience BW …

  8. 06-04-2024 | Benzodiazepine | Online First

    Hypnotics and Incident Dementia: A Risk Assessment

  9. Open Access 01-12-2024 | Dementia | ReviewPaper

    Equine-assisted services for people living with dementia: a systematic review

    Dementia is an umbrella term for a collection of conditions that affect cognitive function [ 1 , 2 ]. Types of dementia include vascular dementia, Lewy body disease, and frontotemporal dementia. Alzheimer’s disease, accounts for approximately 70% …

  10. Open Access 24-01-2024 | Frontotemporal Dementia | OriginalPaper

    Longitudinal volumetric changes in amygdala subregions in frontotemporal dementia

    Amygdala atrophy has been found in frontotemporal dementia (FTD), yet the specific changes of its subregions across different FTD phenotypes remain unclear. The aim of this study was to investigate the volumetric alterations of the amygdala …

  11. Open Access 01-12-2024 | Dementia | OriginalPaper

    Characteristics, outcomes, facilitators and barriers for psychosocial interventions on inpatient mental health dementia wards: a systematic review

    The already high prevalence of dementia and the significant predicted increase in those diagnosed with the condition in the coming decades has been widely documented [ 1 ]. Behavioural and psychological symptoms of dementia, which can include …

  12. 06-04-2024 | Parkinson's Disease | Online First

    Peripheral immune profile in drug-naïve dementia with Lewy bodies

    Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia after Alzheimer’s disease (AD). DLB shares clinically and pathologically common features with Parkinson’s disease (PD) and PD with dementia, and they form Lewy …

  13. Open Access 21-04-2024 | Frontotemporal Dementia | Online First

    Age-specific prevalence of the different clinical presentations of AD and FTD in young-onset dementia

    The prevalence of all-cause dementia increases exponentially from ages 65 to 85, doubling every 5 years [ 1 , 2 ], and continues to increase even after the age of 90 [ 3 ]. In a recent epidemiological study conducted in the province of Modena …

  14. Open Access 01-12-2024 | Alzheimer's Disease | OriginalPaper

    Development of a smartphone screening test for preclinical Alzheimer’s disease and validation across the dementia continuum

    Dementia has been described by the Lancet 2017 Commission as “the greatest global challenge for health” [ 1 ]. There are huge personal costs for people living with dementia and their families and huge economic costs for social and healthcare …

  15. Open Access 13-04-2024 | Dementia | Online First

    Criminal behavior in alcohol-related dementia and Wernicke–Korsakoff syndrome: a Nationwide Register Study

    Criminal behavior is known to peak in people in their 20s and to decline later in life [ 1 ]. However, arrest rates in older age groups are increasing [ 1 ], and the number and proportion of older prisoners have escalated globally over the past …

  16. Open Access 09-04-2024 | Methotrexate | Online First

    Methotrexate and the Risk of Dementia: A Two-Sample Mendelian Randomization Study

    Methotrexate, the most common disease-modifying antirheumatic drug, is the cornerstone of therapy for many autoimmune diseases and is commonly used in the treatment of rheumatoid arthritis (RA), osteoarthritis, and psoriasis [ 1 – 3 ]. Several …

  17. Open Access 01-12-2024 | Dementia | OriginalPaper

    Potentially inappropriate prescribing for people with dementia in ambulatory care: a cross-sectional observational study

    Dementia is a progressive syndrome caused by underlying neurodegenerative processes and characterised by a decline from a previously attained cognitive level that affects memory, thinking, behaviour and activities of daily living [ 1 ]. The …

  18. Open Access 01-12-2024 | Dementia | OriginalPaper

    Factors influencing the commissioning and implementation of health and social care interventions for people with dementia: commissioner and stakeholder perspectives

    Dementia is a progressive, neurodegenerative, life limiting condition associated with a range of symptoms including memory loss, declining executive function, and associated changes in behaviour and mood [ 5 ]. Over 55 million people live with …

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