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Systemic Lupus Erythematosus 

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  1. 27-04-2024 | Systemic Lupus Erythematosus | Online First

    Prediction model for developing neuropsychiatric systemic lupus erythematosus in lupus patients

    Systemic lupus erythematosus (SLE) is an autoimmune disease, of which neuropsychiatric systemic lupus erythematosus (NPSLE) is a severe manifestation. NPSLE mainly involves the central nervous system (CNS) and peripheral nervous system (PNS) …

  2. 01-12-2024 | Systemic Lupus Erythematosus | OriginalPaper

    A case of choroidal neovascularization as a first manifestaion of systemic lupus erythematosus

    Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder that is responsible for multiple manifestations affecting the dermatologic, neurological, hematological and renal systems [ 1 ]. Frequent manifestations of SLE are fatigue …

  3. 30-04-2024 | Systemic Lupus Erythematosus | Online First

    Belimumab corticosteroid-sparing treatment in systemic lupus erythematosus: a real-life observational study (BESST study)

    Data about the impact of Belimumab on corticosteroid sparing in real life are scarce. To assess the corticosteroid-sparing effect among patients with systemic lupus erythematosus (SLE) treated with Belimumab in real-life settings. Multicentric …

  4. 01-05-2024 | Systemic Lupus Erythematosus | Online First

    SIT1 identifies circulating hypoactive T cells with elevated cytotoxic molecule secretion in systemic lupus erythematosus patients

    This study aims to elucidate the expression and functionality of SIT1 in circulating CD8/CD4 + T cells in humans and to delineate its significance in systemic lupus erythematosus (SLE) patients. We employed multiparametric flow cytometry to …

  5. Open Access 01-12-2024 | Wilson's Disease | OriginalPaper

    Systemic lupus erythematosus combined with Wilson’s disease: a case report and literature review

    Wilson’s disease (WD) is a rare autosomal-recessive disorder characterized by defective biliary excretion of copper, with a reported prevalence of 1:30,000–50,000 [ 1 ]. This defect leads to the progressive accumulation of copper in various organs …

  6. 23-04-2024 | Systemic Lupus Erythematosus | Online First

    Two-dimensional speckle-tracking echocardiography in left ventricular systolic function in patients with systemic lupus erythematosus

    Systemic lupus erythematosus (SLE) is an autoimmune inflammatory connective tissue disease characterized by the production of autoantibodies and the formation of immune complexes, involving multiple organs and systems. The cardiovascular system is …

  7. 02-04-2024 | Systemic Lupus Erythematosus | OriginalPaper

    A predictive model for premature atherosclerosis in systemic lupus erythematosus based on clinical characteristics

    Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by an overactive immune system, with presence of pro-inflammatory cytokines and autoantibodies, manifests with systemic and organ-specific clinical symptoms [ 1 ].

  8. 25-01-2024 | Systemic Lupus Erythematosus | OriginalPaper

    Patients’ Preferences for Systemic Lupus Erythematosus Treatments—A Discrete Choice Experiment

    Systemic lupus erythematosus (SLE) is a chronic autoimmune disease resulting in tissue damage across multiple organ systems, the course of which is often unpredictable and can feature flares and periods of remission [ 1 ]. Patients with SLE are …

  9. 05-04-2024 | Systemic Lupus Erythematosus | OriginalPaper

    Non-thyroidal disease syndrome in patients with systemic lupus erythematosus: relation to disease inflammatory activity

    Systemic lupus erythematosus (SLE) is a multisystem chronic autoimmune disease of connective tissue characterized by the production of autoantibodies and chronic inflammation of organs and tissues. The global prevalence ranges from 13 to 7713.5 …

  10. Open Access 01-12-2024 | Systemic Lupus Erythematosus | OriginalPaper

    Musculoskeletal symptoms in systemic lupus erythematosus patients and their impact on health-related quality of life

    Systemic lupus erythematosus (SLE) is a heterogenous autoimmune disease with a variable clinical course and prognosis [ 1 ]. This heterogeneity poses enormous challenges to diagnostic, medical, and therapeutic progress [ 2 ]. SLE has a remarkable …

  11. 20-03-2024 | Epstein-Barr Virus | OriginalPaper

    A retrospective cohort study of Epstein-Barr virus infection status and systemic lupus erythematosus

    Systemic lupus erythematosus (SLE) is a devastating systemic autoimmune disease caused by immune dysregulation and characterized by the production of a large number of autoantibodies leading to multiple organ involvement. Signs and symptoms of SLE …

  12. 23-03-2024 | Systemic Lupus Erythematosus | Erratum

    Correction to: Neurofilament light in plasma is a potential biomarker of central nervous system involvement in systemic lupus erythematosus

  13. 26-04-2024 | Systemic Lupus Erythematosus | Online First

    No clear influence of treatment escalation on flare prevention in serologically active clinically quiescent patients with systemic lupus erythematosus: a retrospective cohort study

    This study aimed to clarify the efficacy and safety of treatment escalation by initiating therapeutic agents in serologically active clinically quiescent (SACQ) patients with systemic lupus erythematosus (SLE). We retrospectively evaluated SACQ …

  14. 06-04-2024 | Systemic Lupus Erythematosus | Online First

    Hormone and reproductive factors and risk of systemic lupus erythematosus: a Mendelian randomized study

    Systemic lupus erythematosus (SLE) is an autoimmune and inflammatory disease with a risk associated with hormonal and reproductive factors. However, the potential causal effects between these factors and SLE remain unclear. A two-sample Mendelian …

  15. 05-04-2024 | Hydroxychloroquine | Online First

    Factors associated with early hydroxychloroquine-induced retinal toxicity in patients with systemic lupus erythematosus

    Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by the formation of autoantibodies and deposition of immune complexes that cause tissue damage in multiple organs [ 1 ]. Treatment of SLE includes the use of antimalarial …

  16. 15-04-2024 | Systemic Lupus Erythematosus | Online First

    A more detailed description of study methods could be needed: Comments on “Clinico-serological associations of urinary activated leukocyte cell adhesion molecule in systemic lupus erythematosus and lupus nephritis”

  17. Open Access 01-12-2024 | Positron Emission Tomography | OriginalPaper

    Brain 18 F-FDG PET reveals cortico-subcortical hypermetabolic dysfunction in juvenile neuropsychiatric systemic lupus erythematosus

    Juvenile systemic lupus erythematosus (j-SLE) is a rare pediatric chronic auto-immune disease (prevalence rate: 3.76/100 000 in France in 2010) affecting multiple organs including brain leading to possible neuropsychiatric (NP) features [ 1 ].

  18. Open Access 02-04-2024 | Systemic Lupus Erythematosus | Online First

    Pregnancies in patients with systemic lupus erythematosus during 2000–2018 in Finland: a case–control study

    The onset of systemic lupus erythematosus (SLE) is often during patients’ reproductive years, and pregnancies in female SLE patients are common. Therefore, many potential threats exist regarding family planning. Of particular concern is active …

  19. 21-03-2024 | Systemic Lupus Erythematosus | ReviewPaper

    Pancytopenia with aplastic anemia in systemic lupus erythematosus: case series and literature review

    Aplastic anemia (AA) is a rare, potentially catastrophic hematopoiesis failure manifested by pancytopenia and bone marrow aplasia. AA occurrence in Systemic Lupus Erythematosus (SLE) patients is extremely rare. The diagnosis may be delayed due to …

  20. 23-02-2024 | Systemic Lupus Erythematosus | OriginalPaper

    Glucocorticoid use and varying doses on the long-term outcomes of offspring born to patients with systemic lupus erythematosus

    This study aims to assess the impact of non-fluorinated glucocorticoid use and varying doses on the long-term physical, neurological, and social-emotional development outcomes of offspring born to patients with systemic lupus erythematosus (SLE).

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