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Cardiology Coronary Heart Disease

Coronary Heart Disease

23-04-2024 Circulatory Disease News

Triglyceride levels reduced by olezarsen

Olezarsen administered monthly for 6 months reduces triglyceride levels in patients with severe hypertriglyceridemia who are at increased CV risk.

Editor's Choice

Incentivised to exercise

Employing strategies that earn points or a small amount of money motivates people at high risk of heart disease or stroke to walk  more each day than they would otherwise.

What causes premature coronary artery disease?

Understanding the genetic and non-genetic causes underlying premature coronary artery disease is vital, given the rising incidence of the disease.

Statin therapy linked to moderately increased risk for diabetes

09-04-2024 Statins News

Statin therapy leads to small increases in glycemia that translates into a moderate increase in diabetes diagnoses versus placebo.

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Episode 3: Unravelling resistant hypertension

Why is it so difficult to diagnose and manage?

Resistant hypertension is a difficult to treat and often misunderstood phenomenon that continues to frustrate cardiologists. 

In this episode, Professors Morris Brown and Bryan Williams debate the causes of resistant hypertension and explore novel treatment options.

Prof. Morris Brown
Prof. Bryan Williams

Case Studies

Syncope due to coronary artery spasm

Open Access Cardiac Syncope Case Study

Ischemia without obstructive coronary artery disease can be difficult to identify. In this case, the patient presented with recurrent syncope which was caused by coronary artery spasm microvascular dysfunction and effectively treated.

How to diagnose mediastinal angiosarcoma

Open Access Hemangiosarcoma Case Study

A mediastinal angiosarcoma presented mimicking signs of constrictive pericarditis, aortic dissection, and coronary artery disease. The correct diagnosis only was made measurement of hyaluronic acid concentration in the pleural fluid.

Aslanger’s pattern on an ECG

Open Access Myocardial Infarction Case Study

The case of acute coronary syndrome presenting with an ECG displaying Aslanger’s pattern. Severe stenosis of the distal left main coronary artery and the proximal segment of the left anterior descending artery was observed via coronary angiography.

Current Reviews

Chinese Herbal Medicines for Coronary Heart Disease: Clinical Evidence, Pharmacological Mechanisms, and the Interaction with Gut Microbiota

Coronary heart disease (CHD) is a common type of cardiovascular disease (CVD) that has been on the rise in terms of both incidence and mortality worldwide, presenting a significant threat to human health. An increasing body of studies has shown …

Cardiac disease in Cushing’s syndrome. Emphasis on the role of cardiovascular magnetic resonance imaging

Cushing’s Syndrome (CS) is clinically defined as the symptoms and signs associated with long-term glucocorticoid (GC) excess of either endogenous or exogenous origin. Exogenous CS is caused by intake of oral, parenteral, inhaled or topical …

Intensified glycemic control by HbA1c for patients with coronary heart disease and Type 2 diabetes: a review of findings and conclusions

Open Access Coronary Heart Disease Review

The occurrence and development of coronary heart disease (CHD) are closely linked to fluctuations in blood glucose levels. While the efficacy of intensified treatment guided by HbA1c levels remains uncertain for individuals with diabetes and CHD …

Efficacy and safety of oral Chinese patent medicines in the treatment of coronary heart disease combined with hyperlipidemia: a systematic review and network meta-analysis of 78 trials

Open Access Coronary Heart Disease Review

According to the World Health Organization (WHO), approximately 17.9 million people die from cardiovascular disease each year worldwide. This disease is the biggest threat to human health, with over 500 million patients globally. Coronary heart …

Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
Developed by: Springer Medicine

Further Reading

The Use of Precision Epigenetic Methods for the Diagnosis and Care of Stable Coronary Heart Disease Reduces Healthcare Costs

Open Access Coronary Heart Disease Original Research

Coronary heart disease (CHD) is the leading cause of death in both the USA and the world [ 1 ]. According to the American Heart Association, by 2035, nearly 45% of the American population will have some form of heart disease [ 2 ]. The prevalence …

The value of lipid accumulation products in predicting type 2 diabetes mellitus: a cross-sectional study on elderlies over 65 in Shanghai

Open Access Type 2 Diabetes Research article

Type 2 diabetes mellitus (T2DM), one of the leading non-communicable diseases in the middle-aged population worldwide, is largely attributed to recent changes in diets and lifestyles [ 1 , 2 ]. As estimated by the International Diabetes Federation …

The overall fractions of coronary heart diseases and depression attributable to multiple dependent psychosocial work factors in Europe

Open Access Coronary Heart Disease Original Article

Psychosocial work factors were found to be associated with various health outcomes and especially with mental health and cardiovascular outcomes (Niedhammer et al. 2021 ). Although the etiological effects of these factors have been explored …

Role of inflammatory signaling pathways involving the CD40–CD40L–TRAF cascade in diabetes and hypertension—insights from animal and human studies

Open Access Coronary Heart Disease Original Contribution

CD40L–CD40–TRAF signaling plays a role in atherosclerosis progression and affects the pathogenesis of coronary heart disease (CHD). We tested the hypothesis that CD40L–CD40–TRAF signaling is a potential therapeutic target in hyperlipidemia …