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14-06-2024 Dyslipidemia News

Plozasiran shows promise for mixed hyperlipidemia

Plozasiran shown to significantly reduce triglyceride levels in patients with mixed hyperlipidemia in the phase 2b MUIR trial. 

Dual defibrillator pads needed in patients with obesity

12-06-2024 Atrial Fibrillation News

In people with obesity and atrial fibrillation, dual direct-current cardioversion is more effective than single DCCV in restoring sinus rhythm.

BRASH syndrome with digoxin toxicity

Open Access Bradyarrhythmia Case Study

BRASH syndrome (bradycardia, renal failure, atrioventricular node blocking, shock, and hyperkalemia) in this case by triggered extreme dehydration, was complicated by concomitant digoxin.

PGD in heart transplantation: the challenge to survive

Open Access Heart Transplantation Review

Primary graft dysfunction is a life-threatening condition with a high mortality rate. Despite efforts, the definition, diagnosis and best treatment approaches remain controversial.

HF from a cutaneous hemangioma

Free for a limited time Hemangioma Case Study

Large cutaneous hemangiomas can be hemodynamically significant, resulting in high-output heart failure and pulmonary hypertension. Embolization and resection is effective and well-tolerated.

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Episode 11: Cardiac rehabilitation in patients with frailty

The essentials of individualised rehab programmes for elderly patients with CVD and frailty

Nearly half of adults over the age of 65 have some degree of frailty, and over two-thirds have cardiac disease.

Dr. Eduard Shantsila discusses the importance of individualised rehabilitation programmes in these patients, to reduce morbidity and mortality, and improve quality of life.

Dr. Eduard Shantsila

BRASH syndrome with digoxin toxicity

Open Access Bradyarrhythmia Case Study

BRASH syndrome (bradycardia, renal failure, atrioventricular node blocking, shock, and hyperkalemia) in this case by triggered extreme dehydration, was complicated by concomitant digoxin.

HF from a cutaneous hemangioma

Free for a limited time Hemangioma Case Study

Large cutaneous hemangiomas can be hemodynamically significant, resulting in high-output heart failure and pulmonary hypertension. Embolization and resection is effective and well-tolerated.

Overlooked effect of angiotensin receptor–neprilysin inhibitor

Free for a limited time Medical Side Effect Case Study

Caution is needed when assessing insulin secretion capability and nephropathy in patients with diabetes who are being treated with an angiotensin receptor–neprilysin inhibitor.

Current Reviews

Special considerations for hypertension in women

Open Access Hypertension Review

Guidelines for the treatment of high blood pressure are similar for both sexes, with little consideration for sex-specific factors. Tailored considerations are needed for women, especially around gestational or post-menopausal hypertension.

Evaluation of the Safety and Effectiveness of Oral Minoxidil in Children: A Systematic Review

Open Access Minoxidil Review

The minimal adverse-effect profile and positive clinical response of low-dose oral minoxidil (LDOM) have recently caused the drug to gain popularity for the treatment of hair disorders in adults. However, in the pediatric population, hesitancy …

Sex and Gender-related Disparities in Clinical Characteristics and Outcomes in Heart Transplantation

Heart transplant (HT) constitutes the gold standard of treatment for patients with advanced heart failure (AHF) in the absence of significant comorbidities [ 1 ].

Towards the Fifth Pillar for the Treatment of Heart Failure with Reduced Ejection Fraction: Vericiguat in Older and Complex Patients

Open Access Heart Failure Review Article

Heart failure with reduced ejection fraction (HFrEF) represents an emerging epidemic, particularly affecting frail, older, and multimorbid patients. Current therapy for the management of HFrEF includes four different classes of disease-modifying …

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Webinar | 08-11-2023 | 18:00 (CET)

Keynote webinar | Spotlight on diet and diabetes

An expert-led symposium exploring the prevention and management of type 2 diabetes through dietary interventions. Highlights include discussion of the recent EASD guidelines, therapeutic diets, food types and processing, plus psychological factors that influence patient success, and the drivers of healthy eating and diabetes control.

Prof. Mike Lean
Prof. Falko Sniehotta
Developed by: Springer Medicine

Vodcasts | Case Scenarios (Link opens in a new window)

Expert guidance on the multidisciplinary approach to identifying and managing chronic kidney disease in patients with type 2 diabetes, plus patient scenarios to assist your decision-making and put the latest clinical guidelines into context.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Webinar (Link opens in a new window)

Interact with experts from established amyloidosis centers who can offer you specialized guidance to support your mission to set up a local center. Network with other HCPs in your locality to discuss region-specific challenges in establishing amyloidosis centers. 

Supported by:
  • AstraZeneca and Alexion
Developed by: Springer Healthcare IME

Further Reading

German Cardiac Arrest Registry (G-CAR)—results of the pilot phase

Open Access Cardiopulmonary Resuscitation Original Paper

In Europe, more than 300,000 patients suffer from out-of-hospital cardiac arrest (OHCA) every year [ 1 ]. Despite medical progress leading to a trend towards decreased mortality rates of OHCA patients [ 2 , 3 ], reported survival rates with good …

Dietary and genetic determinants of non-alcoholic fatty liver disease in coronary heart disease patients

Open Access Non-Alcoholic Fatty Liver Disease Original Contribution

Non-alcoholic fatty liver disease (NAFLD) is considered as the hepatic manifestation of cardiometabolic disorders [ 1 ] and has been associated with an increased risk of cardiovascular diseases events in the general population [ 2 ] and with an …

Comparative analysis of the addition of empagliflozin versus doubling the furosemide dose in decompensated heart failure

Open Access Empagliflozin Original Article

Heart failure represents not a disease in itself but rather a syndrome characterized by a combination of signs and symptoms stemming from the heart’s inability to effectively pump blood to support the circulatory system, whether at rest or during …

Special considerations for hypertension in women

Open Access Hypertension Review

Guidelines for the treatment of high blood pressure are similar for both sexes, with little consideration for sex-specific factors. Tailored considerations are needed for women, especially around gestational or post-menopausal hypertension.

Related topics

HF from a cutaneous hemangioma

Free for a limited time Hemangioma Case Study

Large cutaneous hemangiomas can be hemodynamically significant, resulting in high-output heart failure and pulmonary hypertension. Embolization and resection is effective and well-tolerated.

Read more

Role of hypertension in CV outcomes in children with CKD

Open Access Chronic Kidney Disease Review

Cardiovascular health is critical to the long-term outcomes of children with chronic kidney disease. Recognizing and treating hypertension is vital for improving outcomes in these young patients. 

Read more