EASD 2023

Weekly insulin icodec is noninferior to once-daily insulin degludec in people with type 1 diabetes, indicate findings from the ONWARDS 6 trial.

SURMOUNT-3 results indicate tirzepatide can enhance the weight loss achieved following an intensive lifestyle intervention.

The insulin analog faster aspart is a viable alternative to insulin aspart as a treatment for pregnant and breastfeeding women with type 1 and type 2 diabetes.

The SURPASS-6 findings support the addition of tirzepatide to basal insulin for people with poorly controlled type 2 diabetes, demonstrating significant improvements in mean glycated hemoglobin and other benefits compared with use of adjunct insulin lispro.

Diabetes increases the risk of development of depressive symptoms, with this study finding a significant linear relationship between diabetes severity and risk of depression.

A new phase 2 study shows that the insulin-producing function of beta cells is preserved for longer periods of time in people with newly diagnosed type 1 diabetes who are treated with antivirals pleconaril and ribavirin.

Real-world data from 23,442 patients taking weekly semaglutide injections shows improvement in weight and HbA_1c levels over a 3-year period, with more pronounced results in patients with greater adherence to treatment.

Low muscle mass increases risk of all-cause mortality in people with diabetes, with double the risk for cardiovascular-disease-related deaths compared to those with normal muscle mass.

Women who have experienced gestational diabetes have a higher risk of developing chronic kidney disease, with an increased risk of 92% compared to women without GDM.

Both SGLT2 inhibitors and GLP-1 receptor agonists have been shown to lower the risk of microvascular complications over a 5-year period in people with type 2 diabetes, according to a large retrospective cohort analysis.

In the past 15 years, mortality rates after a first heart attack have dropped significantly for people with type 2 diabetes but this is not the case for people with type 1 diabetes.

Adolescents and young adults with type 2 diabetes have a higher risk of myocardial infarction and heart failure compared to their peers with type 1 diabetes.

New evidence-based European guidelines provide strengthened and expanded recommendations on dietary management of type 2 diabetes, including dietary patterns, environmental sustainability, food processing, and patient support.

Exercise provides health benefits for individuals with type 1 diabetes, through reducing CVD, improving skeletal muscle health and increasing fitness [ 1 , 2 ]. Despite the benefits of exercise, barriers to its use as a diabetes therapy remain.

Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common liver disease worldwide. The risk of developing MAFLD varies among individuals, due to a combination of environmental inherited and acquired genetic factors.

Exercise improves metabolic control in part by increasing muscle glucose uptake during muscle contractions by insulin independent mechanisms and by increasing skeletal muscle insulin sensitivity following exercise [ 1 – 5 ]. Indeed, skeletal muscle …