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Ankylosing Spondylitis 

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  1. Open Access 01-12-2024 | Ankylosing Spondylitis | OriginalPaper

    Identification and bioinformatics analysis of lncRNAs in serum of patients with ankylosing spondylitis

    Ankylosing spondylitis (AS) is a common chronic inflammatory disease with an autoimmune etiology [ 1 ]. AS often affects the axial joints, including the sacroiliac joint and spine, and induces new bone formation and ultimately ankylosis [ 2 , 3 ].

  2. 10-04-2024 | Multiple Sclerosis | Online First

    Multiple sclerosis associated with adalimumab use in ankylosing spondylitis

    Multiple sclerosis (MS) is a chronic inflammatory central nervous system (CNS) demyelinating disease. Balo-like lesion is a specific MRI manifestation with alternating layers of demyelination and myelination; it has been found in a variety of CNS …

  3. Open Access 02-05-2024 | Psoriatic Arthritis | Online First

    Risk Stratification of Patients with Psoriatic Arthritis and Ankylosing Spondylitis for Treatment with Tofacitinib: A Review of Current Clinical Data

    In this commentary, we review clinical data which helps inform individualized benefit–risk assessment for tofacitinib in patients with psoriatic arthritis (PsA) and ankylosing spondylitis (AS). ORAL Surveillance, a safety trial of patients ≥ 50 …

  4. Open Access 25-04-2024 | Opioids | Online First

    Opioid use surrounding diagnosis and follow-up in patients with ankylosing spondylitis, psoriatic arthritis, and rheumatoid arthritis: Results from US claims databases

    Ankylosing spondylitis (AS), psoriatic arthritis (PsA), and rheumatoid arthritis (RA) These diseases are commonly reported in order of prevalence, however, in this manuscript they are presented alphabetically. are chronic inflammatory diseases that …

  5. Open Access 29-04-2024 | Psoriatic Arthritis | Online First

    Safety Profile of Upadacitinib up to 5 Years in Psoriatic Arthritis, Ankylosing Spondylitis, and Non-radiographic Axial Spondyloarthritis: An Integrated Analysis of Clinical Trials

    Psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA), encompassing non-radiographic axial spondyloarthritis (nr-axSpA) and ankylosing spondylitis (AS), are inflammatory rheumatic diseases defined as spondyloarthritis (SpA) [ 1 ]. While …

  6. Open Access 01-12-2024 | Ankylosing Spondylitis | Erratum

    Retraction Note: Reduced immunomodulation potential of bone marrow-derived mesenchymal stem cells induced CCR4+CCR6+ Th/Treg cell subset imbalance in ankylosing spondylitis

  7. Open Access 07-05-2024 | Ankylosing Spondylitis | Online First

    Genetic variability of three common NK and γδ T cell receptor genes (FCγ3R, NCR3, and DNAM-1) and their role in Polish patients with rheumatoid arthritis and ankylosing spondylitis

    Various lymphocyte subpopulations, including NK cells as well as γδ T cells, have been considered an important element in the pathogenesis of autoimmune, inflammatory, rheumatic diseases, such as rheumatoid arthritis (RA) and ankylosing

  8. 08-01-2024 | Ankylosing Spondylitis | Letter

    Comment on: Bone density and fracture risk factors in ankylosing spondylitis: a meta-analysis

  9. 22-03-2024 | Ankylosing Spondylitis | Online First

    The Role of H3K27me3-Mediated Th17 Differentiation in Ankylosing Spondylitis

    Ankylosing spondylitis (AS) is a common chronic progressive inflammatory autoimmune disease. T helper 17 (Th17) cells are the major effector cells mediating AS inflammation. Histone 3 Lys 27 trimethylation (H3K27me3) is an inhibitory histone …

  10. Open Access 18-04-2024 | Ixekizumab | Online First

    Exploring the Effects of Ixekizumab on Pain in Patients with Ankylosing Spondylitis Based on Objective Measures of Inflammation: Post Hoc Analysis from a Large Randomized Clinical Trial

    Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that affects approximately 1% of adults [ 1 ]. AxSpA is characterized by back pain due to inflammation of the spine and sacroiliac joints, peripheral joint involvement, and …

  11. 13-02-2024 | Ankylosing Spondylitis | OriginalPaper

    Progression of subclinical atherosclerosis in ankylosing spondylitis: a 10-year prospective study

    Chronic systemic inflammation contributes to increased CVD burden in Ankylosing Spondylitis (AS). Since long-term follow-up data on subclinical atherosclerosis acceleration are lacking, we examined its progression in contemporary AS patients …

  12. Open Access 01-12-2024 | Ankylosing Spondylitis | OriginalPaper

    The causal relationship between immune cells and ankylosing spondylitis: a bidirectional Mendelian randomization study

    Ankylosing spondylitis (AS) is a kind of spine arthritis that mostly affects the spine, sacroiliac joints, spinal attachment sites, and other axial bones, causing chronic inflammatory damage and loss of joint function [ 1 ]. AS is a chronic …

  13. 31-01-2024 | TNF-Inhibitors | Online First

    “Long-term MRI findings in Ankylosing spondylitis patients treated with TNF inhibitors for a decade”

    Ankylosing spondylitis (AS) is an inflammatory rheumatic disease that predominantly impacts the axial skeleton, including the sacroiliac joints (SIJ) and the spine [ 1 ]. The disease is more frequently found in populations with a higher prevalence …

  14. Open Access 01-12-2024 | Ankylosing Spondylitis | OriginalPaper

    A new mathematical model for evaluating surface changes in the mid-abdominal sagittal plane after two-level pedicle reduction osteotomy in patients with ankylosing spondylitis

    Ankylosing spondylitis (AS) is a chronic systemic rheumatic disease that mainly affects the sacroiliac joints and axial skeleton and can lead to severe thoracolumbar kyphosis in the late stage [ 1 ]. Corrective spinal osteotomy can effectively …

  15. Open Access 01-12-2024 | Ankylosing Spondylitis | OriginalPaper

    Decreased expression of NAT10 in peripheral blood mononuclear cells from new-onset ankylosing spondylitis and its clinical significance

    Ankylosing spondylitis (AS) is a type of rheumatic disease that leads to systemic inflammation and osteogenesis, and is a highly disabling and destructive type of arthritis [ 1 ]. AS attack mostly young people and affect 0.09%-0.3% of the global …

  16. Open Access 29-11-2023 | Ankylosing Spondylitis | Erratum

    Correction: Clinical and Economic Benefit of Advanced Therapies for the Treatment of Active Ankylosing Spondylitis

  17. 16-12-2023 | Ankylosing Spondylitis | OriginalPaper

    Cost Effectiveness of Tofacitinib for the Treatment of Active Ankylosing Spondylitis in Greece

    Ankylosing spondylitis (AS) is a chronic, progressive, inflammatory, multidimensional, musculoskeletal disease primarily involving the axial skeleton [ 1 ]. Similarly, to other chronic diseases, AS is associated with increased morbidity and …

  18. 15-09-2023 | Ankylosing Spondylitis | OriginalPaper

    A lower frequency of inflammatory back pain in male patients with ankylosing spondylitis compared with female patients

    In routine rheumatology practice, we noticed that a significant number of male ankylosing spondylitis (AS) patients did not experience inflammatory back pain (IBP). Based on this observation, we aimed to investigate the prevalence of IBP in male …

  19. 14-12-2023 | Ankylosing Spondylitis | Letter

    Rebuttal letter on “Association of radiological severity of hip involvement with clinical characteristics and sagittal spinopelvic balance in patients with ankylosing spondylitis

  20. 09-10-2023 | Ankylosing Spondylitis | ReviewPaper

    Bone density and fracture risk factors in ankylosing spondylitis: a meta-analysis

    Ankylosing spondylitis (AS) is a chronic and progressive inflammatory disease that primarily affects the spine and sacroiliac joints [ 1 ]. Its prevalence varies globally due to regional and ethnic differences. According to a study [ 2 ], the …

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