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18-04-2024 Tuberculosis News

Shortened rifampicin regimen promising as a tuberculosis preventive treatment

A 2-month regimen of daily rifampicin at 20 mg/kg has a comparable safety profile to the standard 4-month regimen of 10 mg/kg, but an inexplicably lower completion rate.

A case of relapsing bronchopneumonia

Open Access Pneumonia Case Study

A patient with bronchopneumonia due to community-associated methicillin-resistant Staphylococcus aureus had an unusual course, which involved repeated relapses and needed extended antibiotic treatment.

Are surveillance biopsies after lung transplantation necessary?

Free for a limited time Lung Transplantation Review

In people undergoing lung transplantation, graft function can be monitored via routinely scheduled surveillance biopsies or via noninvasive assessments. But which approach is best?

Delayed diagnosis of APAP in patient with dermatomyositis

Open Access Respiratory Medicine Case Study

Differentiating autoimmune pulmonary alveolar proteinosis (APAP) from a flare-up of interstitial pneumonia associated with dermatomyositis is challenging. This case highlights the need for early APAP scrutiny.

CAP misdiagnoses increase unnecessary antibiotic use

One in eight hospitalized patients, particularly those with dementia, are inappropriately diagnosed with community-acquired pneumonia.

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Live Webinar | 02-05-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on sleep in brain health

Live: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.

Dr. Rolf Fronczek
Dr. Sven Rupprecht
Dr. Renata Riha
Developed by: Springer Medicine

A case of relapsing bronchopneumonia

Open Access Pneumonia Case Study

A patient with bronchopneumonia due to community-associated methicillin-resistant Staphylococcus aureus had an unusual course, which involved repeated relapses and needed extended antibiotic treatment.

Delayed diagnosis of APAP in patient with dermatomyositis

Open Access Respiratory Medicine Case Study

Differentiating autoimmune pulmonary alveolar proteinosis (APAP) from a flare-up of interstitial pneumonia associated with dermatomyositis is challenging. This case highlights the need for early APAP scrutiny.

Anti-synthetase syndrome with pneumomediastinum in a child

Open Access Respiratory Medicine Case Study

Anti-synthetase syndrome (ASS) is an autoimmune disorder primarily affecting adult women, but this report describes the first case of ASS complicated with pneumomediastinum in a child.

Next-generation sequencing

Next-generation sequencing is a powerful tool that can identify mutations or fusions in a wide range of cancers, enabling physicians to provide targeted therapy to patients and improve outcomes. 

In this vodcast, Professor Andrew Beggs discusses practical aspects of this technique from the clinical viewpoint. 

Supported by: Illumina, Inc., and Eli Lilly and Company

Prof. Andrew Beggs
Developed by: Springer Healthcare

Current Reviews

Challenges in the treatment of pediatric Mycoplasma pneumoniae pneumonia

Mycoplasma pneumoniae (MP) is an important cause of community-acquired pneumonia in children and young adolescents. Despite macrolide antibiotics effectiveness as a first-line therapy, persistence of fever and/or clinical deterioration sometimes …

Research progress on intestinal microbiota regulating cognitive function through the gut-brain axis

The intestinal microbiota community is a fundamental component of the human body and plays a significant regulatory role in maintaining overall health and in the management disease states.The intestinal microbiota-gut-brain axis represents a vital …

Sirtuins and Cellular Senescence in Patients with Idiopathic Pulmonary Fibrosis and Systemic Autoimmune Disorders

Open Access Idiopathic Pulmonary Fibrosis Leading Article

The sirtuin family is a heterogeneous group of proteins that play a critical role in many cellular activities. Several degenerative diseases have recently been linked to aberrant sirtuin expression and activity because of the involvement of …

Targeting KRASG12C in Non-Small-Cell Lung Cancer: Current Standards and Developments

NSCLC Review Article

Among the most common molecular alterations detected in non-small-cell lung cancer (NSCLC) are mutations in Kristen Rat Sarcoma viral oncogene homolog (KRAS). KRAS mutant NSCLC is a heterogenous group of diseases, different from other …

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine

Webinar (Link opens in a new window)

1.25 AMA PRA Category 1 Credit(s)

A collaborative program highlighting the importance of molecular assessments and targeted treatment selection in people with biomarker-positive disease. Submit your questions for the experts now.

Supported by:
  • Roche and Illumina
Developed by: Springer Healthcare IME

Infographic

This expert-led infographic explains how to recognize and manage COPD exacerbations and explores the impact of these exacerbations at the patient and physician level.

Supported by:
  • Sanofi and Regeneron
Developed by: Springer Healthcare

eLearning | Interviews | Digital Treatment Map (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)

Expert-led, multiformat program which will address the individualized management of NSCLC, through education on the detection of NTRK gene fusions, current evidence-based guidelines, and new and emerging therapies. Will also include guidance on integrating shared decision making into your clinical practice, drawing on insights from a patient on how best to communicate.

Supported by:
  • Bayer HealthCare Pharmaceuticals Inc.
Developed by: Springer Healthcare IME
NSCLC Podcast

Episode 7: A deep dive into ADAURA

The ADAURA trial has, as of this year, demonstrated an overall survival benefit with the adjuvant use of osimertinib in people with resectable NSCLC. 

We take an in-depth look at the study with Dr. Luis Paz-Ares, who outlines the study findings, discusses the clinical implications, and addresses the pertinent questions raised by the trial.

Dr. Luis Paz-Ares

Editor's Choice | Respiratory Medicine Journals

Further Reading

Clinical effectiveness of cefiderocol for the treatment of bloodstream infections due to carbapenem-resistant Acinetobacter baumannii during the COVID-19 era: a single center, observational study

Open Access Nosocomial Pneumonia Original Article

Antibiotic resistance is a major global health concern impacting both medical costs and mortality rates [ 1 ]. In particular, resistance to carbapenems in Acinetobacter baumannii exceeds 70% in Southern and Eastern European regions, including Italy …

Endobronchial Ultrasound Guided Transbronchial Needle Aspiration and PD-L1 Yields

Open Access NSCLC INTERVENTIONAL PULMONOLOGY

Lung cancer represents one of the leading causes of cancer-related deaths, but substantial advances have been made in enhancing the ways in which lung cancers are histologically identified and molecularly profiled. As a result, several targeted …

Clinical characteristics, imaging findings, management, and outcomes of patients with scimitar syndrome at a tertiary referral healthcare center in Colombia

Open Access Computed Tomography Original Paper

Scimitar Syndrome is part of a complex spectrum of congenital cardiovascular anomalies related to anomalous pulmonary venous return. Depending on the extent of involvement, treatment can be either expectant or surgical. Prognosis and survival have …

Incidence of pleural effusion with dasatinib and the effect of switching therapy to a different TKI in patients with chronic phase CML

Open Access Pleural Effusion Research

Dasatinib is one of the second generation tyrosine kinase inhibitors (TKI) which is approved for the treatment of patients with chronic phase CML (CP-CML) both in the front line and in the second line setting. Pleural effusion (PE) is a unique …

Related topics

The first case of severe megaloblastic anemia in a patient treated with erlotinib for advanced NSCLC. It highlights the need for close clinical and blood monitoring in people receiving long-term TKI therapy.

Read more