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Surgery

Giant RCA aneurysm mistaken for mediastinal mass

Coronary aneurysms may present with nonspecific symptoms, delaying appropriate management. A suspected cardiac tumor in this patient was revealed to be a giant right coronary artery aneurysm, which was successfully managed with aneurysmectomy and CABG.

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Editor's Choice

Monozygotic twins with discordant thyroid cancers

Familial thyroid cancers are well documented, but in this rare report one monozygotic twin sister had metastatic poorly differentiated thyroid carcinoma and the other recurrent papillary thyroid carcinoma.

Understanding chronic abdominal pain after bariatric surgery

Chronic abdominal pain after bariatric surgery is common, multifactorial, underrecognized, and associated with significant morbidity. Systemic multidisciplinary diagnosis and treatment is essential to optimize outcomes.

Percutaneous closing of an aortopulmonary window

Echocardiography revealed a 3 mm type I aortopulmonary window with minor hypertension in a 3-year-old girl. Transcatheter coil occlusion was successful in closing the defect, highlighting its role as an alternative to surgical repair.

Rethinking surgery in intracerebral hemorrhage

The ENRICH and SWITCH trials challenge longstanding nihilism in ICH. Early minimally invasive surgery appears beneficial in lobar ICH, while decompressive craniectomy may reduce mortality in severe deep ICH.

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Episode 19: GLP-1 medicines - past, present, and future

From diabetes to obesity and beyond

In 2005 the US FDA approved the first GLP-1 medicine for type 2 diabetes, marking the start of a remarkable journey that goes beyond the stimulation of insulin secretion.

Prof. Daniel Drucker gives us a fascinating insight into the early work on GLP-1 and discusses how these medicines are impacting the lives of people with diabetes and obesity. He covers what's known about how they work, treatment duration, side effects, and the role of bariatric surgery, plus what's in the pipeline in terms of drug development and the indications that GLP-1 medicines may be used to treat in the future.

Prof. Daniel Drucker
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Podcast
SPONSORED

Mastering chronic pancreatitis pain: A multidisciplinary approach and practical solutions

Severe pain is the most common symptom of chronic pancreatitis. In this webinar, experts share the latest insights in pain management for chronic pancreatitis patients. Experts from a range of disciplines discuss pertinent cases and provide practical suggestions for use within clinical practice.

Sponsored by:
  • Viatris
Developed by: Springer Health+
Watch now
Video

Case Studies

Giant RCA aneurysm mistaken for mediastinal mass

Coronary aneurysms may present with nonspecific symptoms, delaying appropriate management. A suspected cardiac tumor in this patient was revealed to be a giant right coronary artery aneurysm, which was successfully managed with aneurysmectomy and CABG.

Monozygotic twins with discordant thyroid cancers

Familial thyroid cancers are well documented, but in this rare report one monozygotic twin sister had metastatic poorly differentiated thyroid carcinoma and the other recurrent papillary thyroid carcinoma.

Percutaneous closing of an aortopulmonary window

Echocardiography revealed a 3 mm type I aortopulmonary window with minor hypertension in a 3-year-old girl. Transcatheter coil occlusion was successful in closing the defect, highlighting its role as an alternative to surgical repair.

A quick guide to ECGs

Improve your ECG interpretation skills with this comprehensive, rapid, interactive course. Expert advice provides detailed feedback as you work through 50 ECGs covering the most common cardiac presentations to ensure your practice stays up to date. 

PD Dr. Carsten W. Israel
Developed by: Springer Medizin
Start the cases

Current Reviews

Updated evaluation of additional surgery versus non-gastrectomy treatment for early gastric cancer after noncurative endoscopic resection: a meta-analysis

In general, supplemental surgery with lymph node dissection is primarily suggested for patients who have undergone noncurative resection because of the likelihood of local and further LNM [ 5 , 6 ]. However, some patients firmly refuse additional …

Optimizing Safety and Outcomes in Metabolic/Bariatric Surgery: A Conceptual Framework for Staged Minimally Invasive Treatment

One- and two-step metabolic/bariatric surgery (MBS) procedures have become much safer; yet, some cases may still require revisional surgery. Conventional noninvasive medical management is significantly less effective and durable than MBS, and …

Comparing Cardiovascular Outcomes of GLP-1 Receptor Agonists Versus Metabolic Bariatric Surgery: A Systematic Review and Meta-Analysis

Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, responsible for approximately 17.9 million deaths annually [ 1 ]. Among all the factors contributing to CVD, Obesity plays a dominant role by promoting CVD risk …

Disease activity and maternal–fetal outcomes in pregnant women with cushing’s syndrome: a systematic review and meta‑analysis

Pregnancy in women with Cushing’s syndrome (CS) is uncommon due to the detrimental effects of hypercortisolism on fertility and is associated with an increased risk of maternal and fetal complications. This systematic review evaluated the natural …

CME & eLearning

Case-based insights: ECGs

Improve your ECG interpretation skills with this comprehensive, rapid, interactive course. Expert advice provides detailed feedback as you work through 50 ECGs covering the most common cardiac presentations to ensure your practice stays up to date. 

Developed by: Springer Medizin
SPONSORED

Chronic pancreatitis pain: A multidisciplinary approach and practical solutions

1.5 European CME credits (ECMEC®s)

Severe pain is the most common symptom of chronic pancreatitis. In this live webinar, experts shared the latest insights in pain management for chronic pancreatitis patients. Experts from a range of disciplines discussed pertinent cases and provided practical suggestions for use within clinical practice.

Sponsored by:
  • Viatris
Developed by: Springer Health+

Further Reading

Use of transoral outlet reduction endoscopy (TORE) in the management of resistant dumping syndrome

Luton and Dunstable Hospital (Bedfordshire Hospitals NHS Foundation Trust) is a high-volume tertiary referral bariatric unit in the UK providing obesity care services encompassing a population of 11 million. We maintain a database of all patients …

Updated evaluation of additional surgery versus non-gastrectomy treatment for early gastric cancer after noncurative endoscopic resection: a meta-analysis

In general, supplemental surgery with lymph node dissection is primarily suggested for patients who have undergone noncurative resection because of the likelihood of local and further LNM [ 5 , 6 ]. However, some patients firmly refuse additional …

Neurocognition and health-related quality of life in patients randomized to surgical or transcatheter aortic-valve replacement

Symptomatic aortic stenosis is associated with an adverse prognosis [ 1 ]. Historically, the standard treatment has been surgical aortic valve replacement (SAVR) [ 2 ], whereas in the past two decades, transcatheter aortic valve implantation (TAVI) …

Selective cytotoxicity of solamargine via oxidative stress and caspase-independent mechanisms in human glioblastoma cells

IDH-wild-type glioblastoma (IDH-wildtype GB) is an aggressive and genetically heterogeneous tumor characterized by intrinsic resistance to radiotherapy and chemotherapy, while surgical resection remains inherently limited by its diffuse …

Image Credits
Intraoperative image of giant RCA/© 2026, Paula L. Torres Gómez et al, J Cardiothorac Surg, Poorly differentiated thyroid carcinoma with local invasion and distant metastases/© 2026, Amal El Masri et al, Thyroid Res, Man with stomach / abdominal pain/© urbazon / Getty Images / iStock (symbolic image with model), Fluoroscopic image showing coil placement in APW/© 2025, Hojjat Mortezaeian et al, Cardiothorac Surg, Surgeon gowning up/© Science Photo Library / Getty Images (symbolic image with model), Medicine Matters Podcast promo image/© Springer Medizin GmbH, Papercut liver cradled by hands of child and adult/© happy_lark / iStock / Getty Images Plus, Glasses of wine/© Giovanni Magdalinos / Getty Images / iStock, Artificial heart valve being prepared for surgery, Chronic pancreatitis 3D concept image/© Rasi Bhadramani, Case-Based Insights teaser image/© Eva Künzel