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Albuminuria 

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  1. Open Access 01-04-2024 | Albuminuria | Online First

    Association of visceral adipose tissue with albuminuria and interaction between visceral adiposity and diabetes on albuminuria

    As one of the common chronic diseases, diabetes is a global public health problem, which brings great challenges to human health. Diabetic nephropathy, one of the chronic microvascular complications of diabetes, causes a great impact on the …

  2. 08-04-2024 | Diabetic Nephropathy | Online First

    Ability of NAD and Sirt1 to epigenetically suppress albuminuria

    The time for diabetic nephropathy (DN) to progress from mild to severe is long. Thus, methods to continuously repress DN are required to exert long-lasting effects mediated through epigenetic regulation. In this study, we demonstrated the ability …

  3. 19-01-2024 | Chronic Kidney Disease | OriginalPaper

    Early impact of albuminuria on cardiac function in patients with chronic kidney disease: a prospective study

    Cardiovascular disease (CVD) is the leading cause of end-stage mortality in chronic kidney disease (CKD) patients. However, CVD and CKD are inextricably linked, as microalbuminuria is an independent risk factor for CVD. Herein, we investigated …

  4. Open Access 01-12-2024 | Albuminuria | OriginalPaper

    Association of domain-specific physical activity with albuminuria among prediabetes and diabetes: a large cross-sectional study

    Diabetes mellitus (DM), a common and chronic metabolic disease, is characterized by prolonged elevated blood glucose and insulin resistance (IR), accompanied by complicated clinical complications [ 1 ]. Meanwhile, DM usually affects multiple organs …

  5. Open Access 01-12-2024 | Chronic Kidney Disease | OriginalPaper

    Increased serum methylmalonic acid levels were associated with the presence of cognitive dysfunction in older chronic kidney disease patients with albuminuria

    Chronic kidney disease (CKD) is one of the most common global causes of morbidity and mortality [ 1 ]. Cognitive impairment is commonly found in patients with CKD. A recent systematic review yielded the prevalence of cognitive decline is more …

  6. 10-02-2024 | Albuminuria | Online First

    Impaired sensitivity to thyroid hormones is associated with albuminuria in the euthyroid population: results from NHANES

    Chronic kidney disease (CKD) is a progressive condition that has emerged as a significant cause of mortality and morbidity in the twenty-first century, impacting over 10% of the global population [ 1 ]. Albuminuria, which refers to the excessive …

  7. Open Access 19-01-2024 | Dapagliflozin | OriginalPaper

    Dapagliflozin Utilization in Chronic Kidney Disease and Its Real-World Effectiveness Among Patients with Lower Levels of Albuminuria in the USA and Japan

    This article is published with digital features, including a Graphical Abstract and a Video Abstract, to facilitate understanding of the article. To view digital features for this article, go to https://doi.org/10.6084/m9.figshare.24808380 .

  8. Open Access 01-12-2024 | Albuminuria | OriginalPaper

    Plasma proenkephalin A and incident chronic kidney disease and albuminuria in the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort

    Chronic kidney disease (CKD) is common, costly, and associated with cardiovascular disease and mortality [ 1 – 3 ]. Current screening methods are suboptimal because serum creatinine is insensitive to early reductions in GFR [ 4 ], and nearly 75 …

  9. 13-12-2023 | Diabetes | News | Article

    SGLT2 inhibitors benefit adults with diabetes and non-severe albuminuria

    The renal benefits of SGLT2 inhibitors in adults with diabetes are not limited to those with severe albuminuria, shows a study including patients with predominantly mild to no albuminuria.

  10. 04-12-2023 | Chronic Kidney Disease | News | Article

    Low-dose zibotentan and dapagliflozin reduce albuminuria in chronic kidney disease

    The combination of low-dose zibotentan and dapagliflozin significantly reduces albuminuria in patients with chronic kidney disease with an acceptable safety profile, indicate findings from the ZENITH-CKD trial.

  11. Open Access 01-12-2023 | Hypertensive Retinopathy | OriginalPaper

    Positive correlation between hypertensive retinopathy and albuminuria in hypertensive adults

    Approximately one-third of people in China suffer from hypertension [ 1 ]. Chronic kidney disease (CKD), which is both a cause and complication of hypertension, affects approximately 119.5 million people in China and has become a serious public …

  12. Open Access 26-10-2023 | Albuminuria | OriginalPaper

    Albuminuria and Serum Tumor Necrosis Factor Receptor Levels in Patients with Type 2 Diabetes on SGLT2 Inhibitors: A Prospective Study

    The general goal of diabetes treatment is to reduce mortality and maintain a quality of life comparable to that of healthy individuals; therefore, it is essential to prevent the onset and progression of diabetic complications. Adverse renal events …

  13. Open Access 01-12-2023 | Albuminuria | OriginalPaper

    Differential correlation between time in range and eGFR or albuminuria in type 2 diabetes

    According to the Diabetes Control and Complications Trial (DCCT) and the UK Prospective Diabetes Study (UKPDS) [ 1 , 2 ], hemoglobin A1C is the gold standard for assessing glycaemic control for decades and is strongly associated with the risk of …

  14. Open Access 01-12-2023 | Obesity | OriginalPaper

    Comparison of insulin resistance indices in predicting albuminuria among patients with type 2 diabetes

    Diabetes is the most common metabolic disorder with numerous micro- and macrovascular complications, including, diabetic nephropathy [ 1 , 2 ]. Albuminuria, defined as the presence of albumin in the urine (albumin excretion rate > 30 mg/d), has …

  15. Open Access 01-12-2023 | Albuminuria | OriginalPaper

    Association between elevated serum transaminase and moderately increased albuminuria: a cross-sectional study in western Tokushima, Japan

    Patients with chronic kidney disease (CKD) mainly present with reduced glomerular filtration rates (GFR; < 60 mg/g creatinine [Cr)) and/or symptoms of albuminuria [ 1 ]. Those whose CKD has progressed to end-stage renal disease undergo renal …

  16. 01-11-2023 | Albuminuria | News | Article

    Low eGFR and albuminuria increase risk for multiple adverse outcomes

    Patients with low estimated glomerular filtration rate and albuminuria have an increased risk for multiple adverse outcomes, indicates an individual participant data meta-analysis of more than 27 million adults.

  17. 30-08-2023 | Albuminuria | OriginalPaper

    Association of albuminuria with kidney function and hemodynamic disturbance in pre-school children who undergo congenital heart disease surgery

    With advances in therapeutic strategies for congenital heart disease (CHD), children undergoing complex cardiac surgery are surviving more frequently, and we need to improve their quality of life while being aware of the complications. Given the …

  18. Open Access 01-12-2023 | Macroalbuminuria | OriginalPaper

    Kidney function loss and albuminuria progression with GLP-1 receptor agonists versus basal insulin in patients with type 2 diabetes: real-world evidence

    Around 20–40% of patients with type 2 diabetes have chronic kidney disease (CKD), defined by either reduced kidney function, the presence of albuminuria, or other evidence of kidney damage [ 1 – 4 ]. CKD is associated with an increased risk of …

  19. Open Access 01-12-2023 | Albuminuria | OriginalPaper

    Influence of time factor and albuminuria on characteristics of patients with type 2 diabetes Mellitus before, during and 1 year after COVID-19 recovery

    Human beings have been afflicted by a catastrophic pandemic of coronavirus disease (COVID-19). COVID-19 has enigmatic clinical features and complications from mild respiratory tract infection to critical illness with multiple organ failure [ 1 ].

  20. 11-07-2023 | Albuminuria | OriginalPaper

    Trajectories of eGFR and risk of albuminuria in youth with type 2 diabetes: results from the TODAY cohort study

    Diabetic kidney disease remains the leading cause of kidney failure and is a major cause of morbidity and mortality in type 2 diabetes [ 1 ]. Early diabetic kidney disease, including elevated albuminuria, is frequently present at diagnosis of type …

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