Pediatrics

Methotrexate (MTX) is a folate antagonist with anti-inflammatory, immunomodulatory and anti-proliferative capacities. In low doses, MTX has been established as a first-line effective, safe and inexpensive treatment in immune-mediated inflammatory …

Once thought to be a sterile environment, it is now established that lungs are populated by various microorganisms that participate in maintaining lung function and play an important role in shaping lung immune surveillance. Although our …

The field of nuclear medicine is entering a new era of gamma-camera technology. Solid-state SPECT/CT systems will gradually replace the thallium-activated sodium-iodide NaI(Tl) systems. This digital technology allows drastic improvements in image …

Irritable bowel syndrome (IBS) affects up to 10% of people worldwide and reduces quality of life. The underlying cause of IBS can vary, so finding an effective treatment may require trialling different options. Altering the gut microbiome is an …

Methotrexate (MTX) is a folate antagonist with anti-inflammatory, immunomodulatory and anti-proliferative capacities. In low doses, MTX has been established as a first-line effective, safe and inexpensive treatment in immune-mediated inflammatory …

This article is published with digital features, including a graphical abstract, to facilitate understanding of the article. To view digital features for this article, go to https://doi.org/10.6084/m9.figshare.23932341 .

Celiac Disease (CD) is an autoimmune disease, characterized by an inflammatory reaction in the small intestine, which occurs in genetically susceptible individuals with a chronic gluten intolerance (Rivera et al. 2013 ). Gluten is an …

We investigated whether T cell-recruiting bispecific anti-CD3/GD2 antibody NG-CU might be an alternative to therapeutic anti-GD2 monoclonal antibody (mAb) ch14.18, mediating complement-dependent cytotoxicity (CDC) and antibody-dependent …