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Congress Coverage
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Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on modern management of frailty

LIVE: Thursday 17th October 2024, 18:00-19:30 (CEST)

Frailty has a significant impact on health and wellbeing, especially in older adults. Join our experts to understand the factors that contribute to the development of frailty and find out how to manage the condition and reduce the risk of disability, dependency, and mortality.
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Pediatrics

Transitioning adolescents with dyslipidemia: best practice methods

Young adults with dyslipidemia are at increased risk of premature cardiovascular events due to conflicting age-appropriate advice and no guidelines on best transition practice. Discover the unique needs of these adolescents and young adults. 

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Editor's Choice

ART linked to increased risk for congenital heart defects

Children born after assisted reproductive technology are at increased risk for congenital heart defects versus those born after spontaneous conception.

CAR T-cell therapy for CML in blast phase

A 16-year-old with repeatedly relapsing chronic myeloid leukemia in blast phase achieved a durable response to CAR T-cell therapy when multiple previous treatments had led only to short-term molecular remissions.

Key tests for diagnosing pLGG

Detailed pathological diagnosis – based on a combination of histology, methylation profiling, and sequencing – provides the optimal basis for deciding how to treat pediatric low-grade gliomas.

What caused this child's recurrent abdominal pain?

Intestinal duplication cyst is a rare congenital malformation that is often misdiagnosed because of nonspecific clinical symptoms. Colonoscopy confirmed a cyst involving the colon, appendix, and ileum in this 4-year-old.

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2024 ESMO Congress

Add-on Ra223 could be a new first-line option in mCRPC

Adding radium-223 to first-line enzalutamide significantly improves the survival of patients with bone metastatic castration-resistant prostate cancer.

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AI model can predict tumor mutations

No OS benefit of adding preoperative CRT in gastric cancer

T-DXd supported for breast cancer with brain metastases

» View more highlights on the ESMO 2024 hub page

Latest News

ART linked to increased risk for congenital heart defects

Precocious puberty associated with hidradenitis suppurativa

Multiple metabolic markers may signal SIDS risk for newborns

Lifelong follow-up needed for children undergoing HCT for NMDs

Four brain injury biomarkers linked to concussion in teens

Liraglutide reduces BMI for young children with obesity

Case Studies

CAR T-cell therapy for CML in blast phase

A 16-year-old with repeatedly relapsing chronic myeloid leukemia in blast phase achieved a durable response to CAR T-cell therapy when multiple previous treatments had led only to short-term molecular remissions.

What caused this child's recurrent abdominal pain?

Intestinal duplication cyst is a rare congenital malformation that is often misdiagnosed because of nonspecific clinical symptoms. Colonoscopy confirmed a cyst involving the colon, appendix, and ileum in this 4-year-old.

Recognizing postoperative stress cardiomyopathy

A case of severe stress cardiomyopathy, identified during the postoperative wake-up period, in a patient with scoliosis and pectus excavatum who underwent spinal corrective surgery.

A quick guide to ECGs

Improve your ECG interpretation skills with this comprehensive, rapid, interactive course. Expert advice provides detailed feedback as you work through 50 ECGs covering the most common cardiac presentations to ensure your practice stays up to date. 

PD Dr. Carsten W. Israel
Developed by: Springer Medizin
Start the cases

Current Reviews

Particularities of spasticity in myelomeningocele patients

Myelomeningocele (MMC) is a severe form of spina bifida, a congenital neural tube defect, which is a frequent developmental anomaly of the central nervous system (CNS) [ 1 – 5 ]. MMC is caused by incomplete fusion of the neural folds during the …

Developing CAR T-Cell Therapies for Pediatric Solid Tumors

Chimeric antigen receptor (CAR) T cells have revolutionized the treatment of hematological malignancies, inducing notable and durable clinical responses. However, for solid tumors, including but not limited to pediatric tumors, several peculiar …

Individual child factors affecting the diagnosis of attention deficit hyperactivity disorder (ADHD) in children and adolescents: a systematic review

Attention deficit hyperactivity disorder (ADHD) is a prevalent condition characterised by patterns of inattention, hyperactivity, and impulsivity. This systematic literature review aims to identify the child clinical and sociodemographic factors …

Central venous access device adverse events in pediatric patients with cancer: a systematic review and meta-analysis

Globally, an estimated 400,000 children and adolescents (0–19 years) are diagnosed with cancer annually [ 1 ]. Central venous access devices (CVADs) are essential in facilitating anti-cancer and supportive therapies. CVAD type and timing of …

CME & eLearning

Webcast (Link opens in a new window)

1.0 Interprofessional Continuing Education (IPCE) credit, 1.0 AAPA Category 1 CME credits

DMD remains a progressive incurable disease, but advances in patient-centered care and treatment for cardiopulmonary dysfunction have helped to increase life expectancy. This program equips multidisciplinary teams, including pediatric neurologists, pediatricians, pulmonologists, cardiologists, and endocrinologists, with key knowledge and skills to enhance care throughout the patient journey.

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME

Patient Cases

Improve your ECG interpretation skills with this comprehensive, rapid, interactive course. Expert advice provides detailed feedback as you work through 50 ECGs covering the most common cardiac presentations to ensure your practice stays up to date. 

Developed by: Springer Medizin

Videos | Case Scenarios | Infographics (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)™

Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Pediatrics journals

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Further Reading

Survival Outcomes in US Medicare Patients with Non-Cystic Fibrosis Bronchiectasis by Rate of Baseline Exacerbations

Non-cystic fibrosis bronchiectasis (NCFBE) is a chronic respiratory condition characterized by permanent bronchial dilation, persistent cough and sputum production, and recurrent respiratory infections [ 1 , 2 ]. Recurrent exacerbations, which are …

Predictors of Substantiation in Child Sexual Abuse Investigations in the United States

The present study uses the National Child Abuse and Neglect Data System (NCANDS): Child File. The NCANDS is a national data collection and analysis program that was established by the U.S. Department of Health and Human Services to track the …

Assessment of Biventricular Systolic and Diastolic Function Using Conventional and Strain Echocardiography in Children with Sickle Cell Disease Surviving 1-year After Hematopoietic Stem Cell Transplant

Hematopoietic stem cell transplant (HSCT) is a potentially curative therapy for children with sickle cell disease (SCD). The effects of HSCT on ventricular function are not well characterized in children with SCD. Echocardiograms from children …

Modernizing Newborn Screening in the Genomic Era: Importance of Health-Related Quality of Life

Since their establishment in the 1960s, state-based newborn screening programs in the US have expanded the number of screened conditions alongside technological advances. For example, the development of tandem mass spectrometry has allowed for …

Related topics

Precocious puberty associated with hidradenitis suppurativa

Precocious puberty is more common in young people with the skin condition hidradenitis suppurativa than in those without.

Read more

Rett syndrome: emerging treatment strategies

How can you establish trust with children?

Friedreich ataxia: a bright future?

Vitamin D-dependent rickets complicated with RSV infection

Imaging of sports injuries in adolescents

Multiple metabolic markers may signal SIDS risk for newborns

Multiple metabolic markers that are routinely measured during newborn screening programs are linked to SIDS and may be useful for identifying children at risk soon after they are born.

Read more

Inositols and female reproductive disorders

Recurrent neonatal sepsis linked to increased ROP risk

Improving newborn identification of high-risk CHD cases

Caring for ultra-low birthweight infants

Aciclovir extravasation in a newborn

Transitioning adolescents with dyslipidemia: best practice methods

Young adults with dyslipidemia are at increased risk of premature cardiovascular events due to conflicting age-appropriate advice and no guidelines on best transition practice. Discover the unique needs of these adolescents and young adults. 

Read more

ART linked to increased risk for congenital heart defects

Recognizing postoperative stress cardiomyopathy

Paternal HBV infection status linked to CHD risk

Familial screening for cardiomyopathies and arrhythmias

How can you establish trust with children?

Precocious puberty associated with hidradenitis suppurativa

Precocious puberty is more common in young people with the skin condition hidradenitis suppurativa than in those without.

Read more

Unusual cause of growth arrest, primary amenorrhea, and metabolic syndrome

How can you establish trust with children?

Managing pediatric andrological disorders

An unusual course of diabetes

Lipid abnormalities in youth

CAR T-cell therapy for CML in blast phase

A 16-year-old with repeatedly relapsing chronic myeloid leukemia in blast phase achieved a durable response to CAR T-cell therapy when multiple previous treatments had led only to short-term molecular remissions.

Read more

Key tests for diagnosing pLGG

Managing stroke in sickle cell anemia

Unusual presentation of ALL

Lifelong follow-up needed for children undergoing HCT for NMDs

Gut microbiota and leukemia: a causal relationship?

How can you establish trust with children?

Establishing trust is a foundational skill for healthcare providers who work with children, but there’s no formal training on how to do it well. Now there’s a framework to help you.

Read more

Vitamin D-dependent rickets complicated with RSV infection

Recurrent neonatal sepsis linked to increased ROP risk

COVID-19 accelerates childhood type 1 diabetes progression

Nirsevimab effective against RSV-associated hospitalization

Neurological impact of SARS-CoV-2 or MIS-C in children

CFTR modulator use could be expanded

Many people with cystic fibrosis who do not have genetic variants approved for treatment still respond to treatment with elexacaftor–tezacaftor–ivacaftor.

Read more

Unusual cause of pediatric plastic bronchitis

How can you establish trust with children?

Pediatric hemoptysis: diagnostic and interventional challenges

Vitamin D-dependent rickets complicated with RSV infection

Dislodged PICC tip causing acute respiratory failure

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