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Internal Medicine Rheumatology

Rheumatology

Managing the VTE risk in patients with CTD-ILD

People with connective tissue disease-related interstitial lung disease have an increased risk for developing venous thromboembolisms. What risk factors do clinicians need to be aware of?

Delayed diagnosis of APAP in patient with dermatomyositis

Open Access Respiratory Medicine Case Study

Differentiating autoimmune pulmonary alveolar proteinosis (APAP) from a flare-up of interstitial pneumonia associated with dermatomyositis is challenging. This case highlights the need for early APAP scrutiny.

Decoding statin-associated muscle symptoms

SAMS are the main reason statins are discontinued, but they range in severity and persistence. Learn about self-limited and autoimmune statin myopathy, the factors that impact them, and available treatment strategies.

Approaching bone health in patients with hypopituitarism

Hypopituitarism has a negative impact on bone health throughout life. Patients should be assessed for the presence of bone disorders as early treatment may prevent bone complications from developing.

Treating multisystem inflammatory syndrome in children

MIS-C is a relatively uncommon but severe pediatric complication associated with COVID-19, requiring rapid and intensive treatment. What are the most effective treatment strategies?

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Case Studies

Delayed diagnosis of APAP in patient with dermatomyositis

Open Access Respiratory Medicine Case Study

Differentiating autoimmune pulmonary alveolar proteinosis (APAP) from a flare-up of interstitial pneumonia associated with dermatomyositis is challenging. This case highlights the need for early APAP scrutiny.

Corticosteroids for hydrocephalus in neurosarcoidosis

Open Access Hydrocephalus Case Study

Hydrocephalus is a rare complication of neurosarcoidosis, usually requiring prompt high-dose IV corticosteroids and neurosurgical treatment. Neurosurgery can have severe complications, but select cases may be eligible for drug treatment only.

How to recognise rare Kawasaki disease in neonates

Open Access Kawasaki Disease Case Study

When newborns present with clinical signs such as rash, distal extremity desquamation, and cervical lymph adenitis, and simultaneous increases in peripheral blood leukocyte count and platelets, clinicians should be highly alert to KD even without fever.

Current Reviews

Sleep and Long COVID—A Review and Exploration of Sleep Disturbances in Post Acute Sequelae of SARS-COV-2 (PASC) and Therapeutic Possibilities

Post Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2), also known as PASC, also referred to as “long-haul COVID-19”, Post-COVID Syndrome, chronic COVID syndrome, long-COVID, or Post Acute Coronavirus Disease 2019 …

Quercetin in Osteoporosis Treatment: A Comprehensive Review of Its Mechanisms and Therapeutic Potential

Osteoporosis (OP) is a widespread skeletal disorder globally, chiefly characterized by reduced bone mass and deterioration of bone microarchitecture, contributing to heightened bone fragility and an increased propensity for fractures [ 1 ]. The …

Secondary fracture prevention in primary care: a narrative review

Open Access Osteoporosis Review

The global burden of osteoporosis continues to rise with an ageing population. Untreated osteoporotic fractures not only heighten the risk of subsequent fractures but are associated with excess mortality. Although primary care guidelines …

Proteomics in Patients with Fibromyalgia Syndrome: A Systematic Review of Observational Studies

Open Access Fibromyalgia Neuropathic Pain (A Abd-Elsayed, Section Editor)

Fibromyalgia syndrome (FMS) is a rheumatic disease (ICD-10 M79.7) of unknown etiology, characterized by chronic widespread pain accompanied by potential neuroinflammation [ 1 ], fatigue, stress [ 2 ], memory loss, sleep disturbance, and multiple …

Further Reading

Treatment patterns in women with postmenopausal osteoporosis using abaloparatide: a real-world observational study

Open Access Osteoporosis Original Article

Osteoporosis (OP) is a systemic skeletal disease associated with low bone mineral density (BMD), microarchitectural deterioration, and an increased risk of fracture [ 1 ]. The estimated prevalence of OP in the US is 10.2 million with an additional …

Systematic Literature Review on the Incidence of Herpes Zoster in Populations at Increased Risk of Disease in the EU/EEA, Switzerland, and the UK

Open Access Shingles Original Research

Primary infection by the varicella-zoster virus leads to childhood varicella (chickenpox) in the majority of the population. The virus remains dormant in the dorsal root ganglia, and can be reactivated later in life, causing herpes zoster (HZ) [ 1 …

Rituximab in non-systemic vasculitic neuropathy: a single-center experience

Open Access Rituximab Original Research

Several new treatment options with improved side effect profiles compared to conventional chemotherapeutics for neurological autoimmune disorders, such as multiple sclerosis, but also for rare neuromuscular disorders, such as myasthenia gravis …

Role of triglyceride-glucose index in metabolic assessment of sarcoidosis patients

Open Access Sarcoidosis IM - ORIGINAL

Sarcoidosis is a rare granulomatous disease that can affect any organ. It leads to an increased risk of metabolic syndrome and insulin resistance, due to biochemical pathways involved in low-grade inflammation in both diseases. The aim of our …