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Internal Medicine Rheumatology

Rheumatology

Open Access Respiratory Medicine Case Study

Delayed diagnosis of APAP in patient with dermatomyositis

Differentiating autoimmune pulmonary alveolar proteinosis (APAP) from a flare-up of interstitial pneumonia associated with dermatomyositis is challenging. This case highlights the need for early APAP scrutiny.

Decoding statin-associated muscle symptoms

Free for a limited time Rheumatology Review

SAMS are the main reason statins are discontinued, but they range in severity and persistence. Learn about self-limited and autoimmune statin myopathy, the factors that impact them, and available treatment strategies.

Approaching bone health in patients with hypopituitarism

Free for a limited time Hypopituitarism Review

Hypopituitarism has a negative impact on bone health throughout life. Patients should be assessed for the presence of bone disorders as early treatment may prevent bone complications from developing.

Treating multisystem inflammatory syndrome in children

MIS-C is a relatively uncommon but severe pediatric complication associated with COVID-19, requiring rapid and intensive treatment. What are the most effective treatment strategies?

Abatacept shows promise for arthritis prevention

06-03-2024 Rheumatoid Arthritis News

APIPPRA trial suggests abatacept may reduce the risk of developing rheumatoid arthritis in high-risk individuals.

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Case Studies

Delayed diagnosis of APAP in patient with dermatomyositis

Open Access Respiratory Medicine Case Study

Differentiating autoimmune pulmonary alveolar proteinosis (APAP) from a flare-up of interstitial pneumonia associated with dermatomyositis is challenging. This case highlights the need for early APAP scrutiny.

Corticosteroids for hydrocephalus in neurosarcoidosis

Open Access Hydrocephalus Case Study

Hydrocephalus is a rare complication of neurosarcoidosis, usually requiring prompt high-dose IV corticosteroids and neurosurgical treatment. Neurosurgery can have severe complications, but select cases may be eligible for drug treatment only.

How to recognise rare Kawasaki disease in neonates

Open Access Kawasaki Disease Case Study

When newborns present with clinical signs such as rash, distal extremity desquamation, and cervical lymph adenitis, and simultaneous increases in peripheral blood leukocyte count and platelets, clinicians should be highly alert to KD even without fever.

Current Reviews

Durable Effects of Acupuncture for Knee Osteoarthritis: A Systematic Review and Meta-analysis

Open Access Acupuncture Alternative Treatments for Pain Medicine (C Robinson, Section Editor)

Knee osteoarthritis (KOA) is a degenerative joint disease that results from wear and tear and progressive loss of articular cartilage [ 1 ]. This condition causes chronic pain and locomotor disability, leading to significant impact on mobility …

Management of granulomatosis with polyangiitis complicated by intestinal perforation and pancytopenia: a case report and literature review

Granulomatosis with polyangiitis is a systemic vasculitis. While the classic triad typically comprises otorhinolaryngologic, pulmonary, and renal manifestations, it is essential to recognize that granulomatosis with polyangiitis can affect any …

Whole-body cryotherapy in orthopaedics: current concepts

Cryotherapy General Review

The use of whole-body cryotherapy (WBC) for musculoskeletal ailments is growing. WBC, involving brief exposure to extremely low temperatures, is increasingly used for its analgesic, anti-inflammatory, and antioxidant effects. The paper examines …

Sirtuins and Cellular Senescence in Patients with Idiopathic Pulmonary Fibrosis and Systemic Autoimmune Disorders

Open Access Idiopathic Pulmonary Fibrosis Leading Article

The sirtuin family is a heterogeneous group of proteins that play a critical role in many cellular activities. Several degenerative diseases have recently been linked to aberrant sirtuin expression and activity because of the involvement of …

Further Reading

Optimising patient outcomes: temporal trends in remission rates of rheumatoid arthritis patients in the Australian OPAL dataset between 2009 and 2022

Open Access Rheumatoid Arthritis ORIGINAL ARTICLE

Despite therapeutic advances and focussed management protocols such as treat-to-target (T2T), not all rheumatoid arthritis (RA) patients achieve remission or optimal disease control. There remains a need to investigate whether remission rates have …

Durable Effects of Acupuncture for Knee Osteoarthritis: A Systematic Review and Meta-analysis

Open Access Acupuncture Alternative Treatments for Pain Medicine (C Robinson, Section Editor)

Knee osteoarthritis (KOA) is a degenerative joint disease that results from wear and tear and progressive loss of articular cartilage [ 1 ]. This condition causes chronic pain and locomotor disability, leading to significant impact on mobility …

A Machine Learning Approach for Prediction of CDAI Remission with TNF Inhibitors: A Concept of Precision Medicine from the FIRST Registry

Open Access Rheumatoid Arthritis Original Research

Advances in molecularly targeted anti-rheumatic therapies have revolutionized the management of rheumatoid arthritis (RA) over the past decades. The development of biologic disease-modifying anti-rheumatic drugs (bDMARDs) and targeted synthetic …

Exploring the Effects of Ixekizumab on Pain in Patients with Ankylosing Spondylitis Based on Objective Measures of Inflammation: Post Hoc Analysis from a Large Randomized Clinical Trial

Open Access Ixekizumab Original Research

Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that affects approximately 1% of adults [ 1 ]. AxSpA is characterized by back pain due to inflammation of the spine and sacroiliac joints, peripheral joint involvement, and …