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Photodynamic Therapy 

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  1. Open Access 01-12-2024 | Photodynamic Therapy | OriginalPaper

    Efficacy of adjunctive photodynamic therapy to conventional mechanical debridement for peri-implant mucositis

    Peri-implant mucositis (p-iM) denotes inflammatory changes in the mucosal tissues surrounding dental implants, characterized by inflammation occurring in the absence of any loss of underlying bone support. This condition is often attributed to …

  2. 01-12-2024 | Photodynamic Therapy | ReviewPaper

    Applications of photodynamic therapy in keratitis

    Keratitis is corneal inflammatory disease which may be caused by several reason such as an injury, allergy, as well as a microbial infection. Besides these, overexposure to ultraviolet light and unhygienic practice of contact lenses are also …

  3. 01-12-2024 | Radiotherapy | OriginalPaper

    Association of photobiomodulation and antimicrobial photodynamic therapy in healing after multiple extraction in head and neck post-radiotherapy- a case report and literature review

    Head and neck cancer is the sixth most common cancer, with more than 500,000 cases reported annually worldwide [ 1 ]. Among the treatment options available for this disease, radiotherapy (RT) plays a fundamental role in antineoplastic therapy

  4. Open Access 01-12-2024 | Photodynamic Therapy | OriginalPaper

    Photodynamic therapy upregulates expression of HIF-1α and PD-L1 in related pathways and its clinical relevance in non-small-cell lung cancer

    As a first-line treatment, immune checkpoint inhibitors (ICIs) can induce substantial therapeutic responses in advanced non-small cell lung cancer (NSCLC) [ 1 ]. It is possible, however, that patients may not respond to ICIs or may develop drug …

  5. Open Access 01-12-2024 | Photodynamic Therapy | OriginalPaper

    Synergistic effect of mesoporous silica nanocarrier-assisted photodynamic therapy and anticancer agent activity on lung cancer cells

    Investigating combined treatment methodologies is crucial for addressing the complex nature of cancer. As an emerging strategy, nano-biotechnology encourages the design of unique nanocarriers possessing simultaneous therapeutic application …

  6. Open Access 01-12-2024 | Photodynamic Therapy | OriginalPaper

    Periodontal ligament stem cell-derived exosome-loaded Emodin mediated antimicrobial photodynamic therapy against cariogenic bacteria

    Dental caries, commonly known as tooth decay, is a multifactorial disease that results from the interaction between various environmental, behavioral, and biological factors [ 1 ]. One of the most important biological factors contributing to dental …

  7. 16-03-2024 | OriginalPaper

    Quantitative Changes in Pro-Oncogenic and Tumor-Suppressing MicroRNA in the Regional Lymph Node during Photodynamic Therapy of Experimental Breast Cancer

    We studied quantitative changes in microRNAs in the axillary lymph node (regional lymph node of the mammary gland) and in the breast tumor tissue. The quantity of pro-oncogenic microRNAs (miR-21 and miR-221) in the regional lymph node decreased in …

  8. 06-03-2024 | Photodynamic Therapy | Online First

    Role of Photodynamic Therapy in Osteonecrosis and Osteoradionecrosis of the Jaws: A Systematic Review

    The term "osteonecrosis" is referred to devitalized bone and aetiology ascribed to various reasons. Osteoradionecrosis (ORN) is a condition where patients present with exposed bone due to a non-healing wound more than 3 to 6 months, with a history …

  9. 01-12-2024 | Aspergillus Fumigatus | OriginalPaper

    Variations in irradiation energy and rose bengal concentration for photodynamic antimicrobial therapy of fungal keratitis isolates

    The purpose is to assess the efficacy of rose bengal photodynamic antimicrobial therapy (PDAT) using different irradiation energy levels and photosensitizer concentrations for the inhibition of fungal keratitis isolates. Seven different fungi …

  10. Open Access 01-12-2024 | Prostate Cancer | OriginalPaper

    Follow-up of vascular-targeted photodynamic therapy in a real-world setting

    Nowadays, prostate cancer (PCa) diagnosis is preponed due to widespread PSA testing and improved PCa detection [ 1 – 3 ]. Moreover, due to the use of multiparametric magnetic resonance imaging (mpMRI) and targeted prostate biopsy, PCa can be …

  11. Open Access 01-12-2024 | Photodynamic Therapy | OriginalPaper

    Evaluation of chlorophyll-loaded mesoporous silica nanoparticles for photodynamic therapy on cancer cell lines

    Chlorophyll (Chl) is a promising natural photosensitizer (PS) in photodynamic treatment (PDT). Mesoporous silica nanoparticles (MSNs) were chosen to increase the effectiveness of PDT. This study aimed to evaluate the synergistic efficacy of …

  12. Open Access 01-12-2024 | Photodynamic Therapy | OriginalPaper

    Effect of photodynamic therapy mediated by hematoporphyrin derivatives on small cell lung cancer H446 cells and bronchial epithelial BEAS-2B cells

    To investigate the effects of photodynamic therapy (PDT) mediated by hematoporphyrin derivatives (HPD) on the proliferation of small cell lung cancer H446 cells and bronchial epithelial BEAS-2B cells. H446 cells and BEAS-2B cells were cultured in …

  13. Open Access 01-12-2024 | Laser | OriginalPaper

    Half-dose photodynamic therapy versus 577 nm subthreshold pulse laser therapy in treatment-naive patients with central serous chorioretinopathy

    Central serous chorioretinopathy (CSC) is a posterior segment disease affecting the neurosensory retina. It causes an accumulation of subretinal fluid (SRF) and alteration in the retinal pigment epithelium (RPE) due to choroidal disturbances [ 1 ].

  14. 01-12-2024 | Lichen Sclerosus Et Atrophicus | ReviewPaper

    Topical 5-aminolevulinic acid (ALA)-photodynamic therapy (PDT) for lichen sclerosus of face: case report and literature review

    Lichen sclerosus (LS) is a chronic inflammatory dermatosis typical of the genital region, with rare involvement of extragenital areas and particularly the face. LS therapeutic management is challenging, and common therapies including topical and …

  15. 01-12-2024 | Laser | OriginalPaper

    Association of Papacarie Duo® and low-level laser in antimicrobial photodynamic therapy (aPDT)

    Dental caries is a multifactorial, non-communicable disease. Effective treatment options for minimally invasive removal of carious tissue include Papacarie Duo® gel and antimicrobial photodynamic therapy (aPDT). aPDT involves a combination of a …

  16. Open Access 01-12-2024 | Photodynamic Therapy | OriginalPaper

    Sonic-assisted antibacterial photodynamic therapy: a strategy for enhancing lateral canal disinfection

    The presence and effects of microorganisms and their byproducts play pivotal roles in the development and advancement of endodontic and periapical diseases [ 1 , 2 ]. Recent studies indicate that the enhanced rates of recuperation in the periapical …

  17. Open Access 01-12-2024 | Photodynamic Therapy | OriginalPaper

    Clinical evaluation of photodynamic therapy for oral leukoplakia: a retrospective study of 50 patients

    Owing to the increased risk of developing cancer in or near the lesion area, as well as in other parts of the oral cavity or head and neck region, oral leukoplakia (OLK) is listed as one of the oral potentially malignant disorders (OPMDs) [ 1 ]. A …

  18. Open Access 01-12-2024 | Photodynamic Therapy | OriginalPaper

    Efficacy of photodynamic therapy on candida colonization and clinical symptoms in denture stomatitis: a systematic review and meta-analysis

    Denture stomatitis (DS) is a very common oral inflammatory condition affecting 15% to 70% of removable denture wearers [ 1 – 4 ]. A considerable portion of DS cases are asymptomatic and discovered incidentally during dental examination as an …

  19. Open Access 31-01-2024 | Photodynamic Therapy | Online First

    Intravitreal anti-vascular endothelial growth factor and combined photodynamic therapy for pachychoroid neovasculopathy: long-term treatment outcomes

    Recently, a condition known as pachychoroid neovasculopathy (PNV) has been reported, characterized by maculopathy with macular neovascularization (MNV) and exudative changes [ 1 , 2 ]. PNV shares anatomic features with other pachychoroid diseases …

  20. Open Access 31-01-2024 | Photodynamic Therapy | Online First

    EPR Monitoring of Oxygenation Levels in Tumors After Chlorophyllide-Based Photodynamic Therapy May Allow for Early Prediction of Treatment Outcome

    The tumor microenvironment (TME) is a complex and dynamic system which interacts with tumor cells and defines the effects on tumor development and progression. TME differs significantly from healthy tissue microenvironment and, among others, is …

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