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Internal Medicine Gastroenterology

Gastroenterology

Gut microbiota and leukemia: a causal relationship?

Open Access Leukemia Review

Explore the intricate relationship between the gut microbiota and leukemia, including potentially causal associations that could open new avenues for prevention and treatment.

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Editor's Choice

A dietary cause of bronchiectasis

Open Access Bronchiectasis Case Study

Would you consider gluten as the cause of a persistent cough and sputum production? This case explores the link between celiac disease and bronchiectasis with chronic rhinosinusitis.

ICI-induced encephalitis in a patient with HCC

Only the third reported case of encephalitis in a patient receiving atezolizumab plus bevacizumab for advanced hepatocellular carcinoma. The neurological symptoms quickly improved once steroid pulse therapy was started.

How does hepatic encephalopathy develop?

Open Access Hepatic Encephalopathy Review

Liver injury can trigger neurocognitive abnormalities ranging from subtle impairments to coma. The interplay of infection and inflammation with ammonia is fundamental in the pathogenesis of hepatic encephalopathy.

Comparable success for difficult bile duct cannulation with EUS-RV and precut sphincterotomy

05-09-2024 Biliary Tract Diseases News

Endoscopic ultrasound-guided rendezvous technique is not superior to precut sphincterotomy when used as a salvage technique for difficult biliary cannulation in benign biliary disease.

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Episode 13: Advances in MASLD and MASH

Welcoming a new name and a new treatment

Metabolic dysfunction-associated liver disease is a significant healthcare concern and burden. Until recently there was no approved pharmacologic treatment for the more serious form of the disease, metabolic dysfunction-associated steatohepatitis. 

In this wide-ranging conversation, Prof. Vlad Ratziu explains the rationale behind the recently updated subclassification and nomenclature for steatotic liver disease, puts the therapeutic advance of resmetirom into context, and looks to the future for MASLD and MASH.

Prof. Vlad Ratziu
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SPONSORED

Mastering chronic pancreatitis pain: A multidisciplinary approach and practical solutions

Webinar | 06-02-2024 | 20:00 (CET)

Severe pain is the most common symptom of chronic pancreatitis. In this webinar, experts share the latest insights in pain management for chronic pancreatitis patients. Experts from a range of disciplines discuss pertinent cases and provide practical suggestions for use within clinical practice.

Sponsored by:
  • Viatris
Developed by: Springer Healthcare
Watch now

Case Studies

A dietary cause of bronchiectasis

Open Access Bronchiectasis Case Study

Would you consider gluten as the cause of a persistent cough and sputum production? This case explores the link between celiac disease and bronchiectasis with chronic rhinosinusitis.

ICI-induced encephalitis in a patient with HCC

Only the third reported case of encephalitis in a patient receiving atezolizumab plus bevacizumab for advanced hepatocellular carcinoma. The neurological symptoms quickly improved once steroid pulse therapy was started.

Excellent response to immunotherapy in rare pancreatic cancer

Open Access Pancreatic Cancer Case Study

A patient with pancreatic acinar cell carcinoma responded well to treatment with pembrolizumab and was able to undergo surgery. He remains disease-free 6 months after surgery.

Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe
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Current Reviews

Role of mTOR Inhibitors in Pediatric Liver Transplant Recipients: A Systematic Review

mTOR-Inhibitors Systematic Review

Liver transplantation (LT) is a life-saving procedure for children with end-stage liver disease, acute liver failure, liver tumors, or certain metabolic and genetic disorders [ 1 ] . Significant progress in pre- and post-transplantation care and …

Roles of LncRNA ARSR in tumor proliferation, drug resistance, and lipid and cholesterol metabolism

Renal Cancer REVIEW ARTICLE

Cancer is one of the most serious diseases that threaten human life and health. Among all kinds of diseases, the mortality rate of malignant tumors is the second highest, second only to cardio-cerebrovascular diseases. Cancer treatment typically …

Comparison of the diagnostic accuracy of shear wave elastography with transient elastography in adult nonalcoholic fatty liver disease: a systematic review and network meta-analysis of diagnostic test accuracy

Open Access Steatotic Liver Disease Review

Nonalcoholic fatty liver disease (NAFLD) is common worldwide. The estimated global prevalence of NAFLD was 25.2% in 2018 [ 1 ], and it was reported that 30% of NAFLD patients go on to develop nonalcoholic steatohepatitis (NASH) [ 2 ]. NAFLD is …

Impact of Visceral and Hepatic Fat on Cardiometabolic Health

Open Access Obesity Cardiometabolic Disease (DM and CV) (CJ Lavie, Section Editor)

Obesity is a known risk factor for cardiometabolic disease. Although body mass index (BMI) is an inexpensive and easily accessible metric to define and characterize obesity at a population level, it fails to account for differences in individual …

CME & eLearning

Vodcasts | News | Expert Interviews (Link opens in a new window)

Enhance your evaluation of treatment response in patients with primary biliary cholangitis. Learn how to make informed decisions on management strategies, and discover advances in the treatment landscape. With news, analysis, and updates from EASL Congress 2024.

Supported by:
  • Ipsen
Developed by: Springer Healthcare IME

Webinar (Link opens in a new window)

Interact with experts from established amyloidosis centers who can offer you specialized guidance to support your mission to set up a local center. Network with other HCPs in your locality to discuss region-specific challenges in establishing amyloidosis centers. 

Supported by:
  • AstraZeneca and Alexion
Developed by: Springer Healthcare IME
SPONSORED

Webinar

1.5 European CME credits (ECMEC®s)

Severe pain is the most common symptom of chronic pancreatitis. In this live webinar, experts shared the latest insights in pain management for chronic pancreatitis patients. Experts from a range of disciplines discussed pertinent cases and provided practical suggestions for use within clinical practice.

Sponsored by:
  • Viatris
Developed by: Springer Healthcare

Further Reading

Evaluation of Aluminum and Magnesium Absorption Following the Oral Administration of an Antacid Suspension Containing Magaldrate in Healthy Women Under Fed Conditions

Open Access Magaldrate Original Research

Gastroesophageal reflux disease (GERD) is a common pathology that affects both sexes and all age groups [ 1 ]. The prevalence of GERD and associated digestive symptoms in adults is 10–20% in Western countries, where pregnant women are a special …

Real-world analysis on the use of gamma-hydroxybutyric acid for alcohol withdrawal syndrome in hospitalized patients with diagnosis of cirrhosis

Open Access Liver Cirrhosis IM - ORIGINAL

The present real-world analysis aimed to evaluate and describe the use of gamma-hydroxybutyric acid (GHB) for alcohol withdrawal syndrome (AWS) in hospitalized patients with diagnosis of liver cirrhosis. An 11-year observational retrospective …

Using a modified Delphi procedure to select a PRO-CTCAE-based subset for patient-reported symptomatic toxicity monitoring in rectal cancer patients

Open Access Rectal Cancer

Rectal cancer treatment can result in a wide variety of symptoms that have impact on the health-related quality-of-life of patients. Monitoring treatment-related symptoms experienced by patients using a short, standardized questionnaire which …