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Internal Medicine Gastroenterology and Hepatology

Gastroenterology and Hepatology

Diagnosing perianal fistulizing Crohn’s disease

An update on the diagnosis of pfCD, from clinical examination and assessment tools to current imaging practices, innovations in imaging and biomarkers, and diagnosis of isolated perianal Crohn’s disease.

Read more

Editor's Choice

An unusual cause of gastric outlet obstruction in infancy

A 2-month-old girl presented with repeated projectile nonbilious vomiting. What was the cause of her hugely dilated stomach, prepyloric stricture, and delayed gastric emptying?

Non-celiac enteropathies

Identifying the cause of non-celiac enteropathy can be difficult, with common etiologies including immunodeficiency, infection, medication, and malignancy. Early nutrition support may minimize morbidity.

A-RT promising for high-risk patients with pancreatic cancer

Ablative radiation therapy can be an alternative option to surgery for the treatment of localized, resectable pancreatic ductal adenocarcinoma, particularly in cases of high surgical risk.

YKL-40 linked to GI cancer risk in type 2 diabetes

Raised YKL-40 levels are associated with an increased risk for obesity-related and gastrointestinal cancers, particularly liver cancer, in people with type 2 diabetes.

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Keynote series | Spotlight on managing health in obesity

Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.

Prof. Eva L. Feldman
Prof. Jonette Keri
Developed by: Springer Medicine
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Video
SPONSORED

Mastering chronic pancreatitis pain: A multidisciplinary approach and practical solutions

Severe pain is the most common symptom of chronic pancreatitis. In this webinar, experts share the latest insights in pain management for chronic pancreatitis patients. Experts from a range of disciplines discuss pertinent cases and provide practical suggestions for use within clinical practice.

Sponsored by:
  • Viatris
Developed by: Springer Healthcare
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Video

Case Studies

An unusual cause of gastric outlet obstruction in infancy

A 2-month-old girl presented with repeated projectile nonbilious vomiting. What was the cause of her hugely dilated stomach, prepyloric stricture, and delayed gastric emptying?

Zolbetuximab-related gastritis

Although gastrointestinal adverse events were not uncommon in trials of the novel agent zolbetuximab, they tended to be transient. This is the first report of delayed-onset and persistent gastritis linked to its use.

Colonic ischemia associated with a GLP-1 RA

Although it seems to be a rare complication, there should be a high index of suspicion for colonic ischemia in patients taking a GLP-1 receptor agonist who present with abdominal pain.

Episode 13: Advances in MASLD and MASH

Welcoming a new name and a new treatment

Metabolic dysfunction-associated liver disease is a significant healthcare concern and burden. Until recently there was no approved pharmacologic treatment for the more serious form of the disease, metabolic dysfunction-associated steatohepatitis. 

In this wide-ranging conversation, Prof. Vlad Ratziu explains the rationale behind the recently updated subclassification and nomenclature for steatotic liver disease, puts the therapeutic advance of resmetirom into context, and looks to the future for MASLD and MASH.

Prof. Vlad Ratziu
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Podcast

Current Reviews

The Landmark Series: Organ Preservation in Rectal Cancer—The Watch and Wait Strategy

Radical treatment of rectal cancer has evolved quite significantly over the last few decades with the development of optimal local disease staging with magnetic resonance (MR), refined surgical techniques including total mesorectal excision (TME) …

Endoscopic Therapy for Anastomotic Bleeding in Inflammatory Bowel Disease

Lower gastrointestinal (GI) anastomotic bleeding in patients with inflammatory bowel disease (IBD) is rare but can be detrimental. Time and effective management is critical to prevent morbidity. Endoscopy has emerged as a minimally invasive and …

Advancing Cardiovascular, Kidney, and Metabolic Medicine: A Narrative Review of Insights and Innovations for the Future

Cardiovascular, kidney and metabolic (CKM) conditions are interrelated, significantly contributing to morbidity, mortality and healthcare burden. Despite therapeutic advances, traditional disease-specific approaches often fail to address their …

Switching from Adalimumab Reference Product to and Among Adalimumab Biosimilars Outside the USA: Insights for US Clinicians

Ten adalimumab biosimilars have been introduced in the United States (USA) since 2023, while adalimumab biosimilars have been available for several years in other countries. These experiences of biosimilar uptake outside the USA can inform …

Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe
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Podcast

CME and eLearning

Videos | News (Link opens in a new window)

Update your awareness of the phenotypes and clinical presentations of late-onset genetic cholestasis, learn how to integrate consensus recommendations and diagnostic tools for accurate diagnosis, and discover treatment advances.

Supported by:
  • Ipsen
Developed by: Springer Healthcare IME

Vodcasts | News | Expert Interviews (Link opens in a new window)

Enhance your evaluation of treatment response in patients with primary biliary cholangitis. Learn how to make informed decisions on management strategies, and discover advances in the treatment landscape. With news, analysis, and updates from EASL Congress 2024.

Supported by:
  • Ipsen
Developed by: Springer Healthcare IME

Webinar (Link opens in a new window)

Interact with experts from established amyloidosis centers who can offer you specialized guidance to support your mission to set up a local center. Network with other HCPs in your locality to discuss region-specific challenges in establishing amyloidosis centers. 

Supported by:
  • AstraZeneca and Alexion
Developed by: Springer Healthcare IME

Further Reading

Function-preserving gastrectomy based on the sentinel node concept prevents osteosarcopenia in patients with gastric cancer

Gastric cancer is the fifth most common malignancy worldwide and the third leading cause of cancer-related mortality [ 1 ]. According to Japanese treatment guidelines for gastric cancer, early gastric cancer (EGC) that is not eligible for …

Combined endoscopic-percutaneous approach for magnetic compression anastomosis in post-transplant anastomotic biliary strictures

Liver transplantation is a life-saving procedure for patients with end-stage liver disease, acute liver failure, and primary liver cancer [ 1 , 2 ]. Biliary complications account for the majority of morbidity and mortality following liver …

GLP- 1R status using validated monoclonal antibody in 689 cases of neuroendocrine neoplasm and its correlation with somatostatin receptor scintigraphy, insulin production, and histological grades

Radiolabeled glucagon-like peptide 1 (GLP- 1) analog scintigraphy is a new, high-sensitivity imaging method for detecting small insulinomas. Somatostatin receptor scintigraphy (SRS) is an established method for detecting gastroenteropancreatic …

ESGAR consensus statement on MR imaging in primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is an idiopathic, heterogeneous, cholestatic liver disease characterized by progressive biliary inflammation and fibrosis that leads to complications including cholestasis and liver failure [ 1 ]. “Sclerosing” …

Related topics

Diagnosing perianal fistulizing Crohn’s disease

An update on the diagnosis of pfCD, from clinical examination and assessment tools to current imaging practices, innovations in imaging and biomarkers, and diagnosis of isolated perianal Crohn’s disease.

Read more