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Internal Medicine Gastroenterology

Gastroenterology
Open Access
Epiglottitis
Case Study

Vaping-induced acute epiglottitis

Read more

The second report, and the first in an adult, of acute epiglottitis directly associated with e-cigarettes with no evidence of infection, indicating the need to consider noninfectious primary causes in the differential diagnosis of epiglottitis.

Editor's Choice

22-09-2023
Hepatitis C
News

Mortality rates high after hepatitis C, despite modern antivirals

Hepatitis C mortality rates following successful treatment are still higher compared with the general population.
Open Access
Gastroesophageal Reflux Disease in Pediatrics
Review

Diagnostic tools for gastrointestinal tract disorders

Gastroesophageal reflux and constipation in infants are common reasons for seeking medical support. This review sets out a staged approach to using functional and imaging tools in the diagnostic workup.
20-09-2023
Pancreatic Cancer
News

NALIRIFOX boosts metastatic pancreatic cancer survival

Previously untreated patients with metastatic pancreatic ductal adenocarcinoma derive a significant survival benefit from the use of NALIRIFOX rather than nab-paclitaxel plus gemcitabine.

Case-Based Insights: Oncology and Hematology


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Latest News

25-09-2023
Gastrointestinal Microbiota
News

Effect of the infant microbiome on wheezing at preschool age

22-09-2023
Hepatitis C
News

Mortality rates high after hepatitis C, despite modern antivirals

22-09-2023
Targeted Therapy
News

Novel KRAS inhibitor elicits ‘durable responses’

20-09-2023
Pancreatic Cancer
News

NALIRIFOX boosts metastatic pancreatic cancer survival

15-09-2023
Public Health
News

Cancer screening may not extend life

13-09-2023
Food Allergy
News

Food allergy in infancy linked to respiratory impairment in childhood

Current Reviews

Fatty Liver
Review Article

How non-alcoholic fatty liver disease and cirrhosis affect the heart

Liver diseases affect the heart and the vascular system. Cardiovascular complications appear to be a leading cause of death in patients with non-alcoholic fatty liver disease (NAFLD) and cirrhosis. The predominant histological changes in the liver …
Solid Tumor
Review Article

Long non-coding RNAs: controversial roles in drug resistance of solid tumors mediated by autophagy

Current genome-wide studies have indicated that a great number of long non-coding RNAs (lncRNAs) are transcribed from the human genome and appeared as crucial regulators in a variety of cellular processes. Many studies have displayed a significant …
Fatty Liver

Screening, Diagnosis, and Staging of Non-Alcoholic Fatty Liver Disease (NAFLD): Application of Society Guidelines to Clinical Practice

Metabolic dysfunction-associated steatotic liver disease (MASLD) [ 1 ••], formerly nonalcoholic fatty liver disease (NAFLD) with consideration of cardiometabolic criteria, is a leading cause of chronic liver disease, affecting at least 30% of the …
Open Access
Methotrexate

Oral Versus Subcutaneous Methotrexate in Immune-Mediated Inflammatory Disorders: an Update of the Current Literature

Methotrexate (MTX) is a folate antagonist with anti-inflammatory, immunomodulatory and anti-proliferative capacities. In low doses, MTX has been established as a first-line effective, safe and inexpensive treatment in immune-mediated inflammatory …

Episode 5: Next-generation sequencing

Emerging biomarkers in thyroid and non-small cell lung cancers

Next-generation sequencing is a powerful tool that can identify mutations or fusions in a wide range of cancers, enabling physicians to provide targeted therapy to patients and improve outcomes. In this podcast, Professor Andrew Beggs discusses practical aspects of this technique from the clinical viewpoint.

This content is intended only for healthcare providers and was made possible by educational funding provided by Illumina, Inc., and Eli Lilly and Company.

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Case Studies

Open Access
Epiglottitis
Case Study

Vaping-induced acute epiglottitis

The second report, and the first in an adult, of acute epiglottitis directly associated with e-cigarettes with no evidence of infection, indicating the need to consider noninfectious primary causes in the differential diagnosis of epiglottitis.
Open Access
Liver Transplantation
Case Study

Gastrointestinal complications of post-transplant lymphoproliferative disease

A case series of pediatric patients points to the need for both endoscopy and colonoscopy in those presenting with nonspecific GI symptoms after transplantation for early diagnosis of post-transplant lymphoproliferative disorder.
Free for a limited time
Type 1 Diabetes
Case Study

Delayed-onset type 1 diabetes after immune checkpoint inhibitor monotherapy

DKA occurred after almost 5 years’ nivolumab monotherapy and ICI-induced type 1 diabetes was diagnosed. Patients should be monitored for the development of diabetes whatever the duration of ICI therapy.

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Further Reading

Open Access
Methotrexate

Oral Versus Subcutaneous Methotrexate in Immune-Mediated Inflammatory Disorders: an Update of the Current Literature

Methotrexate (MTX) is a folate antagonist with anti-inflammatory, immunomodulatory and anti-proliferative capacities. In low doses, MTX has been established as a first-line effective, safe and inexpensive treatment in immune-mediated inflammatory …
Open Access
Eosinophilic Esophagitis
Original Research

Emotional Journey of Patients with Eosinophilic Esophagitis

Eosinophilic esophagitis (EoE) is a chronic and progressive type 2 inflammatory disease associated with esophageal dysfunction and eosinophilic infiltration [ 1 ]. The incidence and prevalence of EoE have increased dramatically over time. EoE has a …
Open Access
Hepatitis D
Original Research

Real-World Epidemiology, Treatment Patterns, and Disease Burden of Chronic Hepatitis B and HDV Co-Infection in South Korea

Viral hepatitis is an infection that causes liver inflammation and damage. Several different viruses cause hepatitis, including hepatitis A, B, C, D, and E. While hepatitis C virus (HCV) infection frequently leads to chronic liver disease, recent …
Open Access
Acute Coronary Syndrome

Impacts of Non-alcoholic Fatty Liver Disease on Acute Coronary Syndrome: Evidence and Controversies

Acute coronary syndrome (ACS), a thrombotic, dramatic, and life-threatening complication of atherosclerosis, remains one of the leading causes of death [ 1 ], although substantial progress has been made in the diagnosis and treatment of this …
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