Gastroenterology and Hepatology

Radical treatment of rectal cancer has evolved quite significantly over the last few decades with the development of optimal local disease staging with magnetic resonance (MR), refined surgical techniques including total mesorectal excision (TME) …

Lower gastrointestinal (GI) anastomotic bleeding in patients with inflammatory bowel disease (IBD) is rare but can be detrimental. Time and effective management is critical to prevent morbidity. Endoscopy has emerged as a minimally invasive and …

Cardiovascular, kidney and metabolic (CKM) conditions are interrelated, significantly contributing to morbidity, mortality and healthcare burden. Despite therapeutic advances, traditional disease-specific approaches often fail to address their …

Ten adalimumab biosimilars have been introduced in the United States (USA) since 2023, while adalimumab biosimilars have been available for several years in other countries. These experiences of biosimilar uptake outside the USA can inform …

Gastric cancer is the fifth most common malignancy worldwide and the third leading cause of cancer-related mortality [ 1 ]. According to Japanese treatment guidelines for gastric cancer, early gastric cancer (EGC) that is not eligible for …

Liver transplantation is a life-saving procedure for patients with end-stage liver disease, acute liver failure, and primary liver cancer [ 1 , 2 ]. Biliary complications account for the majority of morbidity and mortality following liver …

Radiolabeled glucagon-like peptide 1 (GLP- 1) analog scintigraphy is a new, high-sensitivity imaging method for detecting small insulinomas. Somatostatin receptor scintigraphy (SRS) is an established method for detecting gastroenteropancreatic …

Primary sclerosing cholangitis (PSC) is an idiopathic, heterogeneous, cholestatic liver disease characterized by progressive biliary inflammation and fibrosis that leads to complications including cholestasis and liver failure [ 1 ]. “Sclerosing” …