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Internal Medicine Gastroenterology


Unmasking mast cell activation syndrome

Free for a limited time Mastocytosis Review

A comprehensive overview of mast cell activation syndrome, with a focus on the prominent gastrointestinal manifestations, some of which can mimic irritable bowel syndrome.

Pulmonary complications of the liver

Free for a limited time Portal Hypertension Review

Pulmonary complications are common in patients with portal hypertension. Learn how to diagnose and treat the most common complications - hepatic hydrothorax, hepatopulmonary syndrome, and portopulmonary hypertension.

Resmetirom shows promise for NASH and liver fibrosis

16-02-2024 Fatty Liver News

Daily resmetirom achieved significantly greater histologic improvement of both nonalcoholic steatohepatitis and liver fibrosis than placebo in the MAESTRO-NASH phase 3 trial.

Current Reviews

Immunogenic cell death in colorectal cancer: a review of mechanisms and clinical utility

Open Access Colorectal Cancer Review

Colorectal cancer (CRC) is a major cause of cancer-related morbidity and mortality worldwide. Despite several clinical advances the survival of patients with advanced colorectal cancer remains limited, demanding newer approaches. The immune system …

Clinical practice guidelines for the nutrition of colorectal cancer patients: a systematic review

Cancer is an ongoing global public health challenge, and its burden is increasing globally [ 1 ]. Among all cancers, colorectal cancer has the third highest incidence and mortality rate in men and the second highest incidence and the third highest …

Insights into lenvatinib resistance: mechanisms, potential biomarkers, and strategies to enhance sensitivity

Lenvatinib Review Article

Lenvatinib is a multitargeted tyrosine kinase inhibitor capable of promoting apoptosis, suppressing angiogenesis, inhibiting tumor cell proliferation, and modulating the immune response. In multiple cancer types, lenvatinib has presented …

Diagnostic performance of blue laser imaging for early detection of gastric cancer: A systematic review and meta-analysis

Gastric Cancer Systematic review with meta-analysis

Gastric cancer (GC) is the third leading cause for cancer-related deaths globally, with over one million new cases and 0.8 million deaths reported in 2020 alone [ 1 ]. Unfortunately, most cases are detected at an advanced stage, resulting in a …

Case Studies

Remission of eosinophilic esophagitis in an elderly patient treated with benralizumab

Open Access Eosinophilic Esophagitis Case Study

A case of EoE complicated by bronchial asthma in an elderly patient. The EoE did not respond to conventional therapy, but improved rapidly after benralizumab was introduced and did not recur after it was discontinued.

Left-sided appendicitis managed laparoscopically

Open Access Appendicitis Case Study

Appendicitis remains the most common abdominal-related emergency that needs urgent surgery. Left-sided appendicitis has rarely been reported, but awareness of this atypical presentation can help avoid delay in diagnosis and management.

Chronic abdominal pain and constipation diagnosed as glycogen storage disease type IX

Open Access Metabolic Disease and Nutrition Case Study

A diagnosis of glycogen storage disease type IX is easy to overlook, but it should be considered in children presenting with unexplained hepatomegaly and elevated transaminase levels. Genetic analysis is vital for accurate diagnosis.

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2.0 NVMDL CME points

Severe pain is the most common symptom of chronic pancreatitis. In this live webinar, experts shared the latest insights in pain management for chronic pancreatitis patients. Experts from a range of disciplines discussed pertinent cases and provided practical suggestions for use within clinical practice

Supported by:
  • Viatris
Developed by: Springer Healthcare

News | Articles | Videos (Link opens in a new window)

Expert insights, latest news and cutting-edge data reported from The Liver Meeting, Boston covering PBC treatment to arm HCPs with the latest information to optimize patients’ outcomes.

Supported by:
  • Ipsen
Developed by: Springer Healthcare IME

Further Reading

Exploring predictors of dysphagia in survivors of head and neck cancer: A cross-sectional study

Open Access Dysphagia Research

Dysphagia, defined as limited swallowing function, affects more than half (54.9%) of survivors of head and neck cancer (sHNC) [ 1 ]. Beyond the physical limitations of swallowing, dysphagia poses a substantial risk of complications that can …

Targeting myeloperoxidase limits myeloid cell immunosuppression enhancing immune checkpoint therapy for pancreatic cancer

Open Access Pancreatic Cancer Research

Pancreatic ductal adenocarcinoma is a devastating disease characterized by an extreme resistance to current therapies, including immune checkpoint therapy. The limited success of immunotherapies can be attributed to a highly immunosuppressive …

Chemokine CCL21 determines immunotherapy response in hepatocellular carcinoma by affecting neutrophil polarization

Open Access Hepatocellular Carcinoma Research

Liver cancer is one of the leading causes of tumor-related deaths worldwide, with the sixth highest incidence and third highest mortality rate currently [ 1 ]. Over 90% cases of primary liver cancers are hepatocellular carcinomas (HCC), and life …

Induction immunotherapy plus chemotherapy followed by definitive chemoradiation therapy in locally advanced esophageal squamous cell carcinoma: a propensity-score matched study

Open Access Cytostatic Therapy Research

Esophageal cancer (EC) ranks as the sixth leading cause of cancer-related death worldwide, resulting in approximately 5.4 million deaths annually [ 1 , 2 ]. Substantial variations exist in the incidence, mortality, and histopathology of esophageal …