Skip to main content
17673 search results for:

Hypercholesterolemia 

sort by |
"newest" sorts results by publication date. "most relevant" also considers factors like how often the search phrase is in the result.
  1. 07-05-2024 | Hypercholesterolemia | Online First

    Evaluating the Effectiveness and Safety of Evinacumab in Treating Hypercholesterolemia and Hypertriglyceridemia: A Systematic Review and Meta-analysis of Randomized Controlled Trials

    Cardiovascular disease is the primary cause of death worldwide and a major cause of disability [ 1 ]. Extensive evidence from epidemiological, genetic, and randomized interventional clinical studies has consistently established a correlation …

  2. Open Access 18-03-2024 | Hypercholesterolemia | Online First

    Gene Editing for the Treatment of Hypercholesterolemia

    Atherosclerotic cardiovascular disease is characterized by the narrowing of the vessel lumen due to the accumulation of cholesterol and inflammatory cells within the arterial wall. The progression of this disease puts human subjects at risk of …

  3. 03-02-2024 | PCSK9 Inhibitor | BriefCommunication

    Measuring Costs of Cardiovascular Disease Prevention for Patients with Familial Hypercholesterolemia in Administrative Claims Data

    Familial hypercholesterolemia (FH) is a hereditary genetic condition affecting the body’s ability to clear low-density lipoprotein cholesterol and increasing one’s risk of cardiovascular disease and events [ 1 ]. Approximately 1 in every 250 people …

  4. Open Access 01-12-2024 | Hypercholesterolemia | OriginalPaper

    Family cascade screening for equitable identification of familial hypercholesterolemia: study protocol for a hybrid effectiveness-implementation type III randomized controlled trial

    This trial will test the comparative effectiveness of two patient-facing implementation strategies that promote family cascade screening for familial hypercholesterolemia: an automated health system-delivered strategy versus a strategy delivered …

  5. Open Access 22-03-2024 | Hypercholesterolemia | Online First

    Costs attributable to hypercholesterolemia in a single period and over the life cycle

    Hypercholesterolemia is a major risk factor for atherosclerotic cardiovascular disease leading to reduced (healthy) life years. The aim of this study is to quantify the societal costs associated with hypercholesterolemia. We use epidemiologic data …

  6. Open Access 13-03-2024 | PCSK9 Inhibitor | Erratum

    Correction to: The Effect of PCSK9 Inhibitors on LDL-C Target Achievement in Patients with Homozygous Familial Hypercholesterolemia: A Retrospective Cohort Analysis

  7. Open Access 08-03-2024 | Hypercholesterolemia | Online First

    Peripheral artery disease: an underdiagnosed condition in familial hypercholesterolemia? A systematic review

    Familial hypercholesterolemia (FH) is one of the most common autosomal dominant genetic diseases, characterized by an increased exposure to elevated low-density lipoprotein cholesterol (LDL-C) levels that result in a propensity for early …

  8. 12-02-2024 | Coronary Heart Disease | News | Article

    Familial hypercholesterolemia: the key to CHD risk?

    medwireNews : Individuals who carry a familial hypercholesterolemia (FH) genetic variant are almost three times more likely to develop coronary heart disease (CHD) than noncarriers, even when their low-density lipoprotein cholesterol (LDL-C) level is only moderately elevated, US researchers report.

  9. Open Access 01-12-2024 | Acute Coronary Syndrome | OriginalPaper

    Prevalence, clinical features and prognosis of familial hypercholesterolemia in Chinese Han patients with acute coronary syndrome after a coronary event: a retrospective observational study

    Familial hypercholesterolemia (FH) is an autosomal semi-dominant disease, characterized by markedly elevated levels of low-density lipoprotein cholesterol (LDL-c) from conception and accelerated atherosclerotic cardiovascular disease, often …

  10. Should newborns be screened for familial hypercholesterolemia?

    Familial hypercholesterolaemia (FH) is an autosomal dominant monogenic condition, resulting in elevated LDL cholesterol from birth and premature cardiovascular disease. Review the evidence for including FH in the UK’s whole-genome sequencing programme.

  11. Open Access 02-01-2024 | Hypercholesterolemia | Report

    The Effect of PCSK9 Inhibitors on LDL-C Target Achievement in Patients with Homozygous Familial Hypercholesterolemia: A Retrospective Cohort Analysis

    Homozygous familial hypercholesterolemia (HoFH) is characterized by substantially elevated LDL-cholesterol (LDL-C) from birth. Patients typically develop cardiovascular disease (CVD) in their second decade as aortic and supra-aortic stenosis [ 1 – …

  12. 03-11-2023 | Hypercholesterolemia | ReviewPaper

    Stratification in Heterozygous Familial Hypercholesterolemia: Imaging, Biomarkers, and Genetic Testing

    Heterozygous familial hypercholesterolemia (HeFH) is the most common monogenic autosomal dominant disorder characterized by high levels of low-density lipoprotein cholesterol (LDL) cholesterol (LDL-C) from birth, enhanced atherogenesis, and early …

  13. 03-01-2024 | Hypercholesterolemia | Online First

    Validation of the self-reported diagnosis of diabetes mellitus, hypercholesterolemia, and hypertension in Iran; STEPS 2016

    The scheme for causes of mortality has changed dramatically with the advent of effective therapies for infectious disease [ 1 ], so that more than half (54%) of all Disability-Adjusted Life Years (DALY) was attributed to Non-Communicable Diseases …

  14. Open Access 01-12-2023 | Hypercholesterolemia | OriginalPaper

    Maternal hypercholesterolemia would increase the incidence of embryo aneuploidy in couples with recurrent implantation failure

    In recent years, more and more infertile couples have had the chance to deliver babies after treatment with vitro fertilization and embryo transfer [ 10 ]. However, 50–60% of couples are still unable to achieve a clinical pregnancy owing to …

  15. Open Access 10-10-2023 | Hypercholesterolemia | ReviewPaper

    Sex Differences in Familial Hypercholesterolemia

    Familial hypercholesterolemia (FH) is an autosomal dominant disease, causing elevated plasma levels of low-density lipoprotein cholesterol (LDL-C) from childhood onward [ 1 ]. LDL-C is a causal risk factor for atherosclerotic cardiovascular disease …

  16. Open Access 01-12-2023 | Hypercholesterolemia | OriginalPaper

    Different clinical phenotypes of a pair of siblings with familial hypercholesterolemia: a case report and literature review

    Familial hypercholesterolemia (FH) is a common, inherited disorder of cholesterol metabolism that leads to high plasma low-density lipoprotein cholesterol (LDL-C) levels and early cardiovascular morbidity and mortality [ 1 ]. The prevalence of …

  17. Open Access 01-12-2023 | Hypercholesterolemia | OriginalPaper

    Metabolic systems approaches update molecular insights of clinical phenotypes and cardiovascular risk in patients with homozygous familial hypercholesterolemia

    Familial hypercholesterolemia (FH) is an inborn errors of metabolism disorder caused by mutations in the gene-encoding low-density lipoprotein receptor (LDLR). Rare mutations in apolipoprotein B (APOB) and proprotein convertase subtilisin/kexin …

  18. Open Access 01-12-2023 | Hypercholesterolemia | OriginalPaper

    Comparing self-reported health interview survey and pharmacy billing data in determining the prevalence of diabetes, hypertension, and hypercholesterolemia in Belgium

    Non-communicable diseases (NCDs), including type 2 diabetes and cardiovascular diseases, are the leading causes of mortality and morbidity globally, particularly in affluent regions like Europe where they are responsible for over 90% of all deaths …

  19. Open Access 01-12-2023 | Obesity | OriginalPaper

    Using random-forest multiple imputation to address bias of self-reported anthropometric measures, hypertension and hypercholesterolemia in the Belgian health interview survey

    Worldwide, 63% of deaths are caused by non-communicable diseases (NCDs). A high proportion of NCDs are preventable by addressing their main physiological risk factors, such as high blood pressure, obesity and hypercholesterolemia [ 1 ]. Accurate …

  20. Open Access 01-12-2023 | Hypercholesterolemia | OriginalPaper

    Efficacy and safety of tafolecimab in Chinese patients with heterozygous familial hypercholesterolemia: a randomized, double-blind, placebo-controlled phase 3 trial (CREDIT-2)

    Heterozygous familial hypercholesterolemia (HeFH) is one of the most common inherited metabolic disorders in humans, with an estimated prevalence of 1:311 worldwide and 1:500 to 1:200 in China in the general population [ 1 – 3 ]. HeFH is primarily …

Filter search results

Search Operators:

„ ... ... “ Finds documents with exactly this word group, in exactly this word order and spelling (e.g., "employer branding").
AND Finds documents with both search terms (e.g., sales AND bonus).
OR Finds documents with one or the other search term (e.g., porsche OR volkswagen).
Blank Space Finds documents with all search terms. Blank space is understood as AND (e.g., man robot production).
NOT Finds documents with no appearance of the word behind NOT (e.g., ford NOT "harrison ford").
COUNT(...)>n Finds documents where the search term is mentioned at least "n" times."n" may be any number (e.g., COUNT(gear)>8).
NEAR(..., ..., ) Finds documents with both search terms in any word order, permitting "n" words as a maximum distance between them. Best choose between 15 and 30 (e.g., NEAR(recruit, professionals, 20)).
* Finds documents with the search term in word versions or composites. The star * marks whether you wish them BEFORE, BEHIND, or BEFORE and BEHIND the search term (e.g., lightweight*, *lightweight, *lightweight*).
? Finds documents with the search termn in different spellings."?" allows only one character (e.g., organi?ation).
& + - Special characters are understood as AND (e.g., Miller Bros. & Sons).

You can use operators in your search query to narrow down your results even more.

Tap the operator, or hover the mouse pointer over it, to read more about how it works.