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At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
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Lifestyle Modifications 

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  1. 12-04-2024 | Prediabetes | Online First

    Construct validity of the 12-item Short Form Health Survey (SF-12) version 2 and the impact of lifestyle modifications on the health-related quality of life among Indian adults with prediabetes: results from the D-CLIP trial

    India has an estimated 101 million adults with type 2 diabetes (T2DM) [ 1 , 2 ]. Disease status alone is insufficient to understand and address the challenges faced by individuals with T2DM or comprehensively assess and monitor the impact of T2DM …

    Author:
    Euisun Pyo, Mary Beth Weber, Jayalakshmi Sivaram, Lisa R. Staimez, Viswanathan Mohan, Ranjit Mohan Anjana, Regine Haardörfer, Harish Ranjani
    Published in:
    Quality of Life Research
  2. 22-08-2023 | Nutrition | ReviewPaper

    Lifestyle modifications for preventing and managing cardiovascular diseases

    Cardiovascular diseases (CVDs) are a prominent cause of death and disability across the globe, and this article provides a comprehensive review of the many risk factors for their onset and progression. It investigates how changes in food and …

    Author:
    Princess Oghenekeno Samuel, Great Iruoghene Edo, Oghenerume Lucky Emakpor, Gift Onyinyechi Oloni, Gracious Okeoghene Ezekiel, Arthur Efeoghene Athan Essaghah, Endurance Agoh, Joy Johnson Agbo
    Published in:
    Sport Sciences for Health > Issue: 1 / 2024
  3. 29-08-2023 | ReviewPaper

    Kidney stones: natural remedies and lifestyle modifications to alleviate their burden

    Kidney stones (KSs) are also known as “nephrolithiasis” or “urolithiasis”, which are derived from the Greek terms “nephros”, which means “kidney”, “uro-”, which means “urinary”, as well as “lithos”, which means “stone”. This disorder is not a …

    Author:
    Rahma Mowaffaq Jebir, Yasser Fakri Mustafa
    Published in:
    International Urology and Nephrology > Issue: 3 / 2024
  4. Open Access 01-12-2023 | Alzheimer's Disease | OriginalPaper

    Memory support training and lifestyle modifications to promote healthy aging in persons at risk for Alzheimer's disease: a digital application supported intervention (Brain Boosters)
    Author:
    S. Tomaszewski Farias, J. Fox, H. Dulaney, M. Chan, S. Namboodiri, D. J. Harvey, A. Weakley, S. Rahman, C. Luna, B. F. Beech, L. Campbell, M. Schmitter-Edgecombe
    Published in:
    BMC Geriatrics > Issue: 1 / 2023
  5. Open Access 22-06-2023 | Hypertension | OriginalPaper

    Association between lifestyle modifications and improvement of early cardiac damage in children and adolescents with excess weight and/or high blood pressure

    Evidence is available that left ventricular hypertrophy (LVH) is independently related to mortality and morbidity from cardiovascular diseases in adults and that arterial hypertension is the most important cause of LVH [ 1 , 2 ]. In adult …

    Author:
    Simonetta Genovesi, Elena Tassistro, Marco Giussani, Laura Antolini, Giulia Lieti, Antonina Orlando, Massimo Montemerlo, Ilenia Patti, Gianfranco Parati
    Published in:
    Pediatric Nephrology > Issue: 12 / 2023
  6. 01-04-2022 | Acne Inversa | OriginalPaper

    Lifestyle modifications associated with symptom improvement in hidradenitis suppurativa patients

    Hidradenitis suppurativa (HS) is a chronic, inflammatory skin condition that affects 0.1% of the United States of America’s population [ 1 ]. The chronic pain, scarring, recurring nature, involvement of intimate areas, and lack of curative …

    Author:
    Paul C. Macklis, Kelly Tyler, Jessica Kaffenberger, Shawn Kwatra, Benjamin H. Kaffenberger
    Published in:
    Archives of Dermatological Research > Issue: 3 / 2022
  7. Open Access 01-12-2021 | Nutrition | OriginalPaper

    Lifestyle modifications after the diagnosis of gynecological cancer

    There is an increasing body of literature regarding the influence of lifestyle factors such as nutrition, the consumption of nicotine and alcohol as well as exercise on the development of different types of tumors and lifestyle is playing an …

    Author:
    Daniela Paepke, Clea Wiedeck, Alexander Hapfelmeier, Marion Kiechle, Christine Brambs
    Published in:
    BMC Women's Health > Issue: 1 / 2021
  8. 20-07-2022 | Insulins | OriginalPaper

    Efficacy of multi-strain probiotic along with dietary and lifestyle modifications on polycystic ovary syndrome: a randomised, double-blind placebo-controlled study

    Polycystic ovary syndrome (PCOS) is a complex hormonal condition affecting the metabolic, reproductive, and psychological functioning of the body [ 1 , 2 ]. Besides, it is associated with heterogeneous signs and symptoms, viz . irregular menstrual …

    Author:
    Ishwarpreet Kaur, Vanita Suri, Naresh Sachdeva, Satya Vati Rana, Bikas Medhi, Nancy Sahni, Jayesh Ahire, Amarjeet Singh
    Published in:
    European Journal of Nutrition > Issue: 8 / 2022
  9. Open Access 01-12-2021 | Care | OriginalPaper

    Healthcare professional-led interventions on lifestyle modifications for hypertensive patients – a systematic review and meta-analysis

    Cardiovascular diseases (CVDs) remain the most common cause of death worldwide, causing 17.3 million (31.5%) deaths globally [ 1 ]. One of the most important risk factors to develop CVDs is hypertension [ 1 ]. Globally WHO reports suggest that 1in …

    Author:
    Indre Treciokiene, Maarten Postma, Thang Nguyen, Tanja Fens, Jurgis Petkevicius, Raimondas Kubilius, Jolanta Gulbinovic, Katja Taxis
    Published in:
    BMC Primary Care > Issue: 1 / 2021
  10. 01-03-2021 | Glibenclamide | OriginalPaper

    Characterization of women with gestational diabetes who failed to achieve glycemic control by lifestyle modifications

    Gestational diabetes mellitus (GDM) is one of the most common medical complications of pregnancy, with a reported incidence of 6–14% of all pregnancies [ 1 , 2 ].

    Author:
    Eyal Krispin, Adi Ashkenazi Katz, Elyasaf Shmuel, Yoel Toledano, Eran Hadar
    Published in:
    Archives of Gynecology and Obstetrics > Issue: 3 / 2021
  11. Open Access 01-12-2020 | Polycystic Ovary Syndrome | OriginalPaper

    Effect of lifestyle modifications on anthropometric, clinical, and biochemical parameters in adolescent girls with polycystic ovary syndrome: a systematic review and meta-analysis

    Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of childbearing age [ 1 ]. Although the precise prevalence of PCOS in adolescent girls is still unknown, a recent meta-analysis conducted on this age group estimated it …

    Author:
    Somayeh Abdolahian, Fahimeh Ramezani Tehrani, Mina Amiri, Delaram Ghodsi, Razieh Bidhendi Yarandi, Mahdi Jafari, Hamid Alavi Majd, Fatemeh Nahidi
    Published in:
    BMC Endocrine Disorders > Issue: 1 / 2020
  12. Open Access 01-12-2019 | Hypertension | ReviewPaper

    Gene and environmental interactions according to the components of lifestyle modifications in hypertension guidelines

    Risk factors for hypertension consist of lifestyle and genetic factors. Family history and twin studies have yielded heritability estimates of BP in the range of 34–67%. The most recent paper of BP GWAS has explained about 20% of the population …

    Author:
    Yoshihiro Kokubo, Sandosh Padmanabhan, Yoshio Iwashima, Kazumasa Yamagishi, Atsushi Goto
    Published in:
    Environmental Health and Preventive Medicine > Issue: 1 / 2019
  13. Open Access 01-12-2021 | OriginalPaper

    A novel approach to educate hospitalized cardiovascular disease patients about lifestyle and behavior modifications

    Cardiovascular diseases (CVDs) are a major cause of death and disability in men and women globally [ 1 ]. Individuals may be born with a cardiovascular condition or acquire it due to unhealthy patterns of behavior and other factors including …

    Author:
    Atiyeh Saboktakin, Mohammad Mehdi Sepehri, Roghaye Khasha
    Published in:
    BMC Medical Informatics and Decision Making > Issue: 1 / 2021
  14. 01-07-2008 | Abstract

    11.4 Lifestyle Modifications in Hypertensives: Who Does it Matter?

    Introduction. Patients are often asked to modify lifestyle and adopt healthier behaviour for prevention and long-term disease management. It is difficult because it means deep and wide life change. But how patients can modify lifestyle if health …

    Author:
    D. Scala, S. Cozzolino, A. Mancini, M. D’avino, G. Caruso, R. Muschera’, G. Colucciello, V. Luciani, D. Caruso
    Published in:
    High Blood Pressure & Cardiovascular Prevention > Issue: 3 / 2008
  15. 01-07-2008 | Abstract

    11.7 Lifestyle Modifications: a Very Good Weapon Against Hypertension

    Introduction. Although all the international guidelines suggest modifications in lifestyle in association with pharmacological therapy to obtain a better control on blood pressure (BP) and limit organ damage, and though advantage is obtained even …

    Author:
    A. Di Patria, A. Lerro, M. Pietrosante, V. Del Villano
    Published in:
    High Blood Pressure & Cardiovascular Prevention > Issue: 3 / 2008
  16. Open Access 01-12-2018 | OriginalPaper

    Lifestyle modifications as therapy for medication refractory post-traumatic headache (PTHA) in the military population of Okinawa

    Traumatic brain injury (TBI) affects 1.7 million Americans and results in 275,000 hospitalizations per year. Among this population, chronic pain has a prevalence of nearly 40%, the majority due to headaches [ 1 – 4 ]. The International …

    Author:
    Virginia B. Baker, Kathryn M. Eliasen, Nawaz K. Hack
    Published in:
    The Journal of Headache and Pain > Issue: 1 / 2018
  17. 01-01-2006 | News

    Pharmacotherapy for the treatment of obesity has only modest benefits and should be used in combination with lifestyle modifications

    The first steps in the treatment of obesity include diet, exercise and behavioural therapy.[ 1 ] Pharmacotherapy should only be considered when such measures have failed to achieve adequate weight loss; UK guidelines stipulate at least a 3-month …

    Published in:
    Drugs & Therapy Perspectives > Issue: 1 / 2006
  18. 01-07-2016 | ReviewPaper

    How Well Can We Control Dyslipidemias Through Lifestyle Modifications?

    The role for lifestyle modifications to correct dyslipidemia(s) is reviewed. Dietary composition is crucial. Replacing saturated fat with MUFA or n-6 PUFA lowers plasma low-density lipoproteins (LDL) cholesterol and ameliorates the LDL/HDL ratio.

    Author:
    Gabriele Riccardi, Olga Vaccaro, Giuseppina Costabile, Angela A. Rivellese
    Published in:
    Current Cardiology Reports > Issue: 7 / 2016
  19. Open Access 01-03-2014 | ReviewPaper

    Lifestyle Modifications and Colorectal Cancer

    Many studies suggest that Western lifestyle and dietary factors may be responsible for the high incidence of colorectal cancer in industrialized countries. Consumption of high amounts of red and processed meat and low intake of fiber and multiple …

    Author:
    Lukasz Durko, Ewa Malecka-Panas
    Published in:
    Current Colorectal Cancer Reports > Issue: 1 / 2014

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