Reactions Weekly 1/2021

Whooping Cough Clinical study

Potential signal for pentavalent vaccine-related febrile seizures

Myocarditis News item

PRAC meeting highlights July 2021: Zynteglo and COVID-19 vaccines

News item

Recall of varenicline lots due to N-nitroso-varenicline impurity

Antiepileptic Drugs News item

Signal for levetiracetam-associated hypokalaemia

Acute Pancreatitis News item

Signal for remdesivir-associated pancreatitis

Lymphoma News item

Tofacitinib increases risk of MI, lung cancer and lymphoma

Guillain-Barré Syndrome Media release

Warning for Janssen COVID-19 vaccine: risk of Guillain-Barré syndrome

Paracetamol Clinical study

Dipyrone increases risk of liver injury versus paracetamol

Budesonide Review

Glucocorticoid-induced adrenal insufficiency: review of the literature

Morphine Clinical study

Morphine use in AHF increases ventilator use and 30-day mortality

Antidepressant Drugs Clinical study

Most antidepressants and antipsychotics may cause hyponatraemia

Levofloxacin Clinical study

Risk of delirium with ampicillin/sulbactam and other antibacterials

Pravastatin Clinical study

Statin use for primary prevention of CVD associated with low risk of AEs

Famotidine News item

Other adverse reaction research

ß-Blockers Case report

β-blockers/verapamil

Guillain-Barré Syndrome Case report

17DD-yellow-fever-vaccine

Thrombocytopenia Case report

225-actinium-PSMA

Rectal Cancer Case report

5-Fluorouracil

Lamivudine Case report

Abacavir/dolutegravir/lamivudine

Dabigatran Case report

Acenocoumarol/dabigatran etexilate/edoxaban

Metabolic Acidosis Case report

Acetazolamide

Tympanotomy Case report

Acetazolamide/apraclonidine/hyaluronidase

Methotrexate Case report

Acitretin/methotrexate

Crohn's Disease Case report

Adalimumab

Adalimumab Case report

Adalimumab

Cataract Case report

Aflibercept

Albendazole Case report

Albendazole

Cough Case report

Albendazole

Multiple Myeloma Case report

Albendazole/dexamethasone/ivermectin

Alemtuzumab Case report

Alemtuzumab

Bullous Pemphigoid Case report

Alogliptin

Nausea Case report

Alpelisib/ipilimumab/nivolumab

Pruritus Case report

Alprostadil/cilostazol/sodium chloride

Alteplase Case report

Alteplase/enalapril

Ciprofloxacin Case report

Amikacin/gentamicin

Bisoprolol Case report

Amiodarone/bisoprolol

Digoxin Case report

Amiodarone/digoxin

Pantoprazole Case report

Amiodarone/pantoprazole

Aortic Valve Replacement Case report

Amiodarone/sotalol

Amnesia Case report

Amlodipine overdose

Bosentan Case report

Amlodipine/bosentan/sildenafil

Leishmania Case report

Amphotericin-B-liposomal

Amphotericin B Case report

Amphotericin-b/dapsone

Ampicillin Case report

Ampicillin

Ampicillin Case report

Ampicillin/ceftriaxone

Anakinra Case report

Anakinra

Autopsy Case report

Antibacterials/dexamethasone/methylprednisolone

Voriconazole Case report

Antibacterials/voriconazole

Antidepressant Drugs Case report

Antidepressants/levodopa/methylprednisolone

Antiepileptic Drugs Case report

Antiepileptic drugs

Antiepileptic Drugs Case report

Antiepileptic drugs

Patent Ductus Arteriosus Case report

Antiepileptic drugs

Antiepileptic Drugs Case report

Antiepileptic drugs/desloratadine

Amphotericin B Case report

Antifungals

Mastitis Case report

Antineoplastics

Case report

Antineoplastics

Medulloblastoma Case report

Antineoplastics

Case report

Antineoplastics

Maintenance Therapy Case report

Antineoplastics

Helicobacter Pylori Case report

Antineoplastics

Rituximab Case report

Antineoplastics

Neutropenia Case report

Antineoplastics

Ruxolitinib Case report

Antineoplastics

Rituximab Case report

Antineoplastics

Dysphonia Case report

Antineoplastics

Warfarin Case report

Antineoplastics/heparin/warfarin

Acute Myeloid Leukemia Case report

Antineoplastics/valsartan/sacubitril

Schizophrenia Case report

Antipsychotics

Epstein-Barr Virus Case report

Antithymocyte-globulin/busulfan/cyclophosphamide

Endoscopy Case report

Antithymocyte-globulin/prednisolone/tacrolimus

Isoniazid Case report

Antituberculars

Isoniazid Case report

Antituberculars

Isoniazid Case report

Antituberculars/pyridoxine

Ribavirin Case report

Antivirals

Adenovirus Case report

Antivirals/antithymocyte globulin/methylprednisolone

Azathioprine Case report

Apremilast/dapsone/immunosuppressants

Anticoagulant Case report

Argatroban

Hypotension Case report

Aripiprazole

Electroconvulsive Therapy Case report

Aripiprazole/methylphenidate/quetiapine

Portal Vein Thrombosis Case report

Aspirin

Thrombocytopenia Case report

Aspirin/AZD-1222

Anticoagulant Case report

Aspirin/heparin

Tricuspid Valve Replacement Case report

Aspirin/phenprocoumon

Folic Acid Case report

Atezolizumab

Encephalitis Case report

Atezolizumab/bevacizumab

Chronic Lymphocytic Leukemia Case report

Atezolizumab/methylprednisolone

Tocilizumab Case report

Atezolizumab/pembrolizumab

Atorvastatin Case report

Atorvastatin

Atracurium Case report

Atracurium besilate/rocuronium bromide/vecuronium bromide

Intoxication Case report

Atropine

Parkinson's Disease Case report

Atropine

Atropine Case report

Atropine/epinephrine

Shock Case report

Atropine/norepinephrine

Merkel Cell Carcinoma Case report

Avelumab/ruxolitinib interaction

Lymphoma Case report

Azathioprine

Infliximab Case report

Azathioprine

Myasthenia Gravis Case report

Azathioprine

Myasthenia Gravis Case report

Azathioprine/immune-globulin/steroids

Itraconazole Case report

Azathioprine/prednisolone

Portal Vein Thrombosis Case report

AZD-1222

Stroke Case report

AZD-1222

Cerebral Sinus Venous Thrombosis Case report

AZD-1222

Thrombocytopenia Case report

Azd-1222/fondaparinux-sodium/heparin

Omalizumab Case report

Azithromycin/favipiravir/hydroxychloroquine

Infliximab Case report

Balsalazide/infliximab/prednisone

Panniculitis Case report

Baricitinib/tofacitinib

Cryotherapy Case report

BCG

Tuberculosis Case report

Bedaquiline

Budesonide Case report

Bee-venom-allergy-immunotherapy

Glucocorticoid Case report

Betamethasone/dexamethasone

Bevacizumab Case report

Bevacizumab

Tooth Extraction Case report

Bevacizumab

Subarachnoid Hemorrhage Case report

Bevacizumab

Hemoptysis Case report

Bevacizumab/cabozantinib/sunitinib

Ovarian Cancer Case report

Bevacizumab/pemetrexed

Tenofovir Case report

Bictegravir/emtricitabine/tenofovir alafenamide

Case report

Biotin

Seminoma Case report

Bleomycin/cisplatin

Neutropenia Case report

Bleomycin/cisplatin/etoposide

Seminoma Case report

Bleomycin/cisplatin/etoposide

Sarcoidosis Case report

Bleomycin/etoposide/platinum-complexes

Prolactinoma Case report

Bromocriptine/cabergoline

Urinary Incontinence Case report

Bupivacaine

Propranolol Case report

Buspirone/escitalopram/lithium

Peripheral Arterial Disease Case report

Calcitriol/warfarin

Myelodysplastic Syndrome Case report

Carboplatin/cisplatin/etoposide

Cystitis Case report

Carboplatin/gemcitabine

Neutropenia Case report

Carboplatin/pemetrexed/pralsetinib

Propranolol Case report

Carvedilol/digoxin/propranolol

Cephalexin Case report

Cefalexin/phenytoin

Ceftriaxone Case report

Ceftriaxone

Azithromycin Case report

Ceftriaxone/vancomycin

Celecoxib Case report

Celecoxib/cloxacillin/durvalumab

Tarsorrhaphy Case report

Cenegermin

Cetuximab Case report

Cetuximab

Chloroquin Case report

Chloroquine/dalteparin sodium/hydroxycarbamide

Dihydralazine Case report

Ciclosporin/prednisolone/tacrolimus

Adenovirus Case report

Cidofovir

Paraneoplastic Cerebellar Degeneration Case report

Cisplatin

Lymphoma Case report

Cisplatin

Multiple Sclerosis Case report

Cladribine

Glaucoma Case report

Clobetasol

Suicide Case report

Clonazepam/pregabalin/sertraline

Clopidogrel Case report

Clopidogrel

Esophagitis Case report

Clozapine

Nausea Case report

Clozapine

Schizophrenia Case report

Clozapine

Cushing's Syndrome Case report

Cobicistat/glucocorticoids interaction

Case report

Colecalciferol overdose

Constipation Case report

Colesevelam

Meropenem Case report

Colistin

Isoniazid Case report

Colistin

Atorvastatin Case report

Convalescent-anti-SARS-CoV-2-plasma

Hypotension Case report

Cotrimoxazole

Case report

Cotrimoxazole

Amphotericin B Case report

Cotrimoxazole/meropenem

Vaccination Case report

COVID-19-Vaccine-Pfizer-BioNTech

Human Alphaherpesvirus 3 Case report

Covid-19-vaccine-pfizer-biontech

Rituximab Case report

Cyclophosphamide/rituximab

Endarterectomy Case report

Dabigatran-etexilate/omeprazole interaction

Case report

Dactinomycin overdose

Dasatinib Case report

Dasatinib

Lymphoma Case report

Dexamethasone

Hyperglycemia Case report

Dexamethasone

Amphotericin B Case report

Dexamethasone

Peritonitis Case report

Dexamethasone

COVID-19 Case report

Dexamethasone/methylprednisolone/prednisolone

Hyperaldosteronism Case report

Dexamethasone/mitotane/spironolactone

Epilepsy Case report

Diazepam/sodium valproate/topiramate interaction

Insulinoma Case report

Diazoxide

Patent Ductus Arteriosus Case report

Diclofenac/paracetamol interaction

Influenza Virus Case report

Diphtheria-vaccine/influenza-virus-vaccine/pneumococcal-vaccine

Metamizole Case report

Dipyrone abuse and dependence

Metamizole Case report

Dipyrone/interferon-β-1b interactions

Rituximab Case report

Disease modifying antirheumatics/mycophenolate

Prostate Cancer Case report

Docetaxel/prednisone

Leuprolide Case report

Docetaxel/sipuleucel-T

Lymphoma Case report

Doxorubicin

Myocarditis Case report

Durvalumab

Gonococcus Case report

Eculizumab

Ritonavir Case report

Efavirenz/lamivudine/tenofovir-disoproxil-fumarate

Gastrointestinal Bleeding Case report

Enbucrilate

Prostate Cancer Case report

Enzalutamide

Insomnia Case report

Ephedrine abuse

Spinal Anesthesia Case report

Ephedrine/pethidine

Nerve Injury Case report

Epinephrine/lidocaine

Migraine Case report

Escitalopram

Etanercept Case report

Etanercept

Expectoration Case report

Ethambutol

Hypoxemia Case report

Etoposide

Aneurysm Case report

Fentanyl

Iron Deficiency Case report

Ferric carboxymaltose

Erectile Dysfunction Case report

Finasteride

Bisoprolol Case report

Flecainide/vernakalant

Candidiasis Case report

Fludrocortisone/hydrocortisone/prasterone

Left Bundle Branch Block Case report

Fluorouracil/oxaliplatin

Bronchial Asthma Case report

Fluticasone propionate

Allergic Rhinitis Case report

Fluticasone-propionate

Esophagus Resection Case report

Furosemide

Acute Myeloid Leukemia Case report

Gemtuzumab ozogamicin

Fenofibrate Case report

Gimeracil/oteracil/tegafur

Multiple Sclerosis Case report

Glatiramer-acetate

Haloperidol Case report

Haloperidol

Pediatric Intensive Care Case report

Haloperidol/quetiapine

Heparin Case report

Heparin

ANCA-Associated Vasculitis Case report

Hydralazine

Tracheostomy Case report

Hydrocortisone

Oseltamivir Case report

Hydroxychloroquine

Systemic Lupus Erythematosus Case report

Hydroxychloroquine

Systemic Lupus Erythematosus Case report

Hydroxychloroquine/immunosuppressants/isotretinoin

Noscapine Case report

Hydroxychloroquine/mycophenolate-mofetil/tacrolimus

Hydroxychloroquine Case report

Hydroxychloroquine/pentosan polysulfate

Systemic Lupus Erythematosus Case report

Hydroxychloroquine/prednisone

Meningitis Case report

Ibrutinib

Stevens-Johnson Syndrome Case report

Ibuprofen

Strabismus Case report

Ifosfamide

Imatinib Case report

Imatinib

Acute Pancreatitis Case report

Imatinib/gefitinib interaction

Meningitis Case report

Immune globulin

Nystagmus Case report

Immune globulin/methylprednisolone/prednisone

Myasthenia Gravis Case report

Immune globulin/pembrolizumab

Craniotomy Case report

Immune-globulin/levetiracetam/methylprednisolone

Anakinra Case report

Immune-globulin/methylprednisolone/tocilizumab

Dysphonia Case report

Immune-globulin/prednisolone/pyridostigmine

Itraconazole Case report

Immunosuppressants

Kidney Transplantation Case report

Immunosuppressants

Methotrexate Case report

Immunosuppressants

Mycophenolate Mofetil Case report

Immunosuppressants

Dengue Virus Case report

Immunosuppressants

SARS-CoV-2 Case report

Immunosuppressants

Vaginal Cancer Case report

Immunosuppressants

Magnetic Resonance Cholangio Pancreatography Case report

Immunosuppressants/nivolumab

Infliximab Case report

Infliximab

Infliximab Case report

Infliximab/methylprednisolone

Insulins Case report

Insulin

Intensive Care Therapy Case report

Iohexol

Tocilizumab Case report

Ipilimumab/methylprednisolone

Melanoma Case report

Ipilimumab/nivolumab

Ileostomy Case report

Ipilimumab/nivolumab

Infliximab Case report

Ipilimumab/nivolumab

Acute Kidney Injury Case report

Ipilimumab/nivolumab

Metastasis Case report

Ipilimumab/nivolumab

Glucocorticoid Case report

Ipilimumab/nivolumab

Melanoma Case report

Ipilimumab/nivolumab/pembrolizumab

Melanoma Case report

Ipilimumab/nivolumab/pembrolizumab

Melanoma Case report

Ipilimumab/nivolumab/prednisolone

Vomiting Case report

Isotretinoin

Sudden Cardiac Death Case report

Itraconazole/osimertinib/tj-48

Ketamine Case report

Ketamine

Anaphylaxis Case report

Ketamine

Status Epilepticus Case report

Ketamine/midazolam

Telbivudin Case report

Lamivudine/telbivudine

Naloxone Case report

Lamotrigine

Cholecystitis Case report

Lenvatinib

Hypertensive Crisis Case report

Lenvatinib

Fertility Case report

Letrozole

Facial Palsy Case report

Levetiracetam

Epilepsy Case report

Levetiracetam

Spinal Anesthesia Case report

Levobupivacaine

Polyneuropathy Case report

Levodopa

Gastrostomy Case report

Levodopa/carbidopa/entacapone

Crizotinib Case report

Lorlatinib

Case report

Magnesium aspartate/potassium aspartate/potassium chloride

Tremor Case report

Magnesium valproate/venlafaxine interaction

Dementia Case report

Memantine

Tachyarrythmia Case report

Metamfetamine

Autopsy Case report

Methadone overdose/abuse

Polio Virus Case report

Methotrexate

Folic Acid Case report

Methotrexate

Laparoscopy Case report

Methotrexate

Methotrexate Case report

Methotrexate/prednisone

Methotrexate Case report

Methotrexate/valproic-acid

Wernicke's Encephalopathy Case report

Methylprednisolone

Tonsillectomy Case report

Methylprednisolone/prednisolone

Vasectomy Case report

Methylprednisolone/prednisone

Insulins Case report

Methylprednisolone/tagraxofusp

Moderate Disorder of Intellectual Development Case report

Miglustat

Metoprolol Case report

Multiple drug interaction/misuse

Losartan Case report

Multiple drugs

Stem Cell Transplantion Case report

Multiple drugs

Acute Lymphoblastic Leukemia Case report

Multiple drugs

Nutrition Case report

Multiple drugs

Azathioprine Case report

Multiple drugs

Colchicine Case report

Multiple drugs

Ampicillin Case report

Multiple drugs

Omeprazole Case report

Multiple drugs

Tarry Feces Case report

Multiple drugs

Erythropoietin Case report

Multiple drugs

Biguanide Case report

Multiple drugs

Etanercept Case report

Multiple drugs

Pravastatin Case report

Multiple drugs

Pulmonary-Function Tests Case report

Multiple drugs

Bronchoscopy Case report

Multiple drugs

Itraconazole Case report

Multiple drugs

Systemic Lupus Erythematosus Case report

Multiple drugs

Budesonide Case report

Multiple drugs

Timolol Case report

Multiple drugs

Verapamil Case report

Multiple drugs

Phototherapy Case report

Multiple drugs

Melanoma Case report

Multiple drugs

Nausea Case report

Multiple drugs

Anakinra Case report

Multiple drugs

Alteplase Case report

Multiple drugs

COVID-19 Case report

Multiple drugs

Evoked Potential Case report

Multiple drugs

Hypotension Case report

Multiple drugs

Azathioprine Case report

Multiple drugs

Adenovirus Case report

Multiple drugs

Spinal Anesthesia Case report

Multiple drugs

Glimepiride Case report

Multiple drugs

Fosinopril Case report

Multiple drugs

Morphine Case report

Multiple drugs

Isoniazid Case report

Multiple drugs

Amphotericin B Case report

Multiple drugs

Mononucleosis Case report

Multiple drugs

Propranolol Case report

Multiple drugs

Rituximab Case report

Multiple drugs

Vomiting Case report

Multiple drugs

Wound Debridement Case report

Multiple drugs

Epstein-Barr Virus Case report

Multiple drugs

Rituximab Case report

Multiple drugs

Myasthenia Gravis Case report

Multiple drugs

Chronic Inflammatory Bowel Disease Case report

Mycophenolate mofetil

Metastasis Case report

Mycophenolate-mofetil/prednisolone/tacrolimus

Tacrolimus Case report

Mycophenolate-mofetil/tacrolimus

Human Papillomavirus Case report

Mycophenolate/prednisone

Cephalexin Case report

Nafcillin/rifampicin

Multiple Sclerosis Case report

Natalizumab

Case report

Nicotine/varenicline

Ovarian Cancer Case report

Niraparib

Kidney Cancer Case report

Nivolumab

Rectoscopy Case report

Nivolumab

Melanoma Case report

Nivolumab

ß-Blockers Case report

Nivolumab

Vasculitis Case report

Nivolumab

Pleural Effusion Case report

Nivolumab/albumin-human

Diarrhea Case report

Nivolumab/pembrolizumab

Acute Pancreatitis Case report

Nivolumab/sorafenib

Tarry Feces Case report

Norepinephrine

Spinal Muscular Atrophy Case report

Nusinersen

Case report

Octreotide

Systemic Lupus Erythematosus Case report

Ofatumumab/rituximab

Angioedema Case report

Olanzapine

Metastasis Case report

Osimertinib

Rectal Cancer Case report

Oxaliplatin

Myotonia Case report

Oxaliplatin

Hemolytic Uremic Syndrome Case report

Paclitaxel

Neutropenia Case report

Paclitaxel/gemcitabine

Suicide Case report

Paracetamol overdose

Polytrauma Case report

Parenteral nutrition supplements

NSCLC Case report

Pembrolizumab

NSCLC Case report

Pembrolizumab

NSCLC Case report

Pembrolizumab

Dysphonia Case report

Pembrolizumab

Magnetic Resonance Cholangio Pancreatography Case report

Pembrolizumab

Pulmonary Nodule Case report

Pembrolizumab

Nystatin Case report

Pembrolizumab/prednisone

Wilson's Disease Case report

Penicillamine

Thrush Case report

Pirbuterol/salmeterol/fluticasone-propionate

Tachyarrythmia Case report

Pixantrone

Cabozantinib Case report

Pralsetinib/selpercatinib

Pravastatin Case report

Pravastatin

Liver Transplantation Case report

Prednisolone

Prednisolone Case report

Prednisolone

Amphotericin B Case report

Prednisolone

Intravascular Ultrasound Case report

Prednisone

Granulomatosis with Polyangiitis Case report

Prednisone/rituximab

Tetraparesis Case report

Propofol

Schizophrenia Case report

Risperidone

Disorders of Intellectual Development Case report

Risperidone

Schizophrenia Case report

Risperidone

Thrombocytopenia Case report

Risperidone

Paracetamol Case report

Rituximab

Rituximab Case report

Rituximab

Lymphoma Case report

Rituximab

Shingles Case report

Rituximab

Spinal Anesthesia Case report

Ropivacaine/unspecified spinal anaesthetic

Roxithromycin Case report

Roxithromycin

Myalgie Case report

Selexipag

Dystonia Case report

Sertraline

Sertraline Case report

Sertraline

Metoprolol Case report

Sertraline/ampicillin/sulbactam

Sildenafil Case report

Sildenafil

Spironolactone Case report

Silybum-marianum

Metastasis Case report

Sintilimab

Acute Kidney Injury Case report

Sirolimus/tacrolimus

Bisoprolol Case report

Sodium valproate

Splenectomy Case report

Somatostatin

Hepatocellular Carcinoma Case report

Sorafenib

Ascites Case report

Tacrolimus

Chronic Pancreatitis Case report

Teduglutide

Glioblastoma Case report

Temozolomide

Vulvovaginal Candidiasis Case report

Terconazole

Lupus Erythematosus Case report

Thalidomide

Liver Transplantation Case report

Thrombin

Tinnitus Case report

Tobramycin

Tocilizumab Case report

Tocilizumab

Tocilizumab Case report

Tocilizumab/warfarin

Cataract Case report

Tozinameran

Cataract Case report

Trypan-blue

Pneumococcus Case report

Vancomycin

Lorazepam Case report

Vilazodone overdose

Itraconazole Case report

Voriconazole

Autopsy Case report

Yohimbine

Liver Transplantation Case report

Yttrium-90

Osteonecrosis Case report

Zoledronic acid

Kidney Cancer Case report

Zoledronic-acid

Glimepiride News item

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Reactions Weekly

Content (408 Articles)