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Migraine 

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  1. Open Access 01-12-2024 | Migraine | OriginalPaper

    Photophobia is associated with lower sleep quality in individuals with migraine: results from the American Registry for Migraine Research (ARMR)

    A migraine attack consists of moderate-to-severe intensity throbbing headache accompanied by a combination of sensory hypersensitivities (e.g., photosensitivity, phonosensitivity, olfactory hypersensitivity, cutaneous allodynia), nausea, and …

  2. Open Access 16-04-2024 | Migraine | Online First

    Acute Treatment Patterns, Migraine Burden, and Healthcare Resource Use in People With Migraine: Results From the OVERCOME (EU) Observational Study

    Migraine is a debilitating neurological condition with an overall prevalence of approximately 15% in Europe [ 1 ], and 1-year prevalences of 12.6% in Spain [ 2 ] and 16.6% in Germany [ 3 ]. Reported prevalence estimates vary between studies …

  3. 25-03-2024 | Migraine | Online First

    Migraine and gasdermin D: a new perspective on the inflammatory basis of migraine

    Migraine is a common and disabling primary headache disorder and inflammation is a proposed factor in the complex ethiology of the disease. Gasdermin D (GSDMD) is a membrane pore-forming protein acting through the caspase system. End result is …

  4. Open Access 01-12-2024 | Migraine | ReviewPaper

    Female-selective mechanisms promoting migraine

    Sexual dimorphism has been revealed for many neurological disorders including chronic pain. Prelicinal studies and post-mortem analyses from male and female human donors reveal sexual dimorphism of nociceptors at transcript, protein and functional …

  5. 26-04-2024 | Migraine | News | Article

    APPRAIS(ing) the use of erenumab in migraine prevention

    People with episodic migraine who have failed previous preventive treatments are more likely to complete a year of treatment and experience a reduction in monthly migraine days with erenumab.

  6. Open Access 01-12-2024 | Migraine | OriginalPaper

    Specific cognitive and psychological alterations are more strongly linked to increased migraine disability than chronic migraine diagnosis

    It is evident in the clinic that migraine affects some individuals more severely than others. To identify this subgroup of more severely affected patients, the International Classification of Headache Disorders (ICHD-3) defines a somewhat …

  7. 18-04-2024 | Vestibular Migraine | Online First

    Focused Update on Migraine and Vertigo Comorbidity

    Over the past three decades, research has established a link between migraine and vestibular symptoms beyond coincidence. As a distinct clinical entity, vestibular migraine is now considered as one of the most common causes of migraine-associated …

  8. Open Access 01-12-2024 | Migraine | ReviewPaper

    CGRP-targeted medication in chronic migraine - systematic review

    Chronic migraine (CM) is a disabling primary headache that affects 3–4% of people with migraine [ 1 ]. CM is the most prevalent type of headache in a tertiary headache center [ 2 ]. The management of CM is challenging due to several associated …

  9. 18-04-2024 | CADASIL | Online First

    The imaging findings of migraine with visual aura in a CADASIL patient

    Head MRI images of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) patients during migraine attacks are rare.

  10. Open Access 12-03-2024 | Migraine | Online First

    Real-world Impact of Fremanezumab on Migraine-Related Health Care Resource Utilization in Patients with Comorbidities, Acute Medication Overuse, and/or Unsatisfactory Prior Migraine Preventive Response

    This article is published with digital features, including graphical abstract, to facilitate understanding of the article. To view digital features for this article, go to https://doi.org/10.6084/m9.figshare.25133801 .

  11. Open Access 01-12-2024 | Migraine | OriginalPaper

    Calcitonin gene-related peptide: a possible biomarker in migraine patients with patent foramen ovale

    The number of migraine (MA) patients worldwide has reached 1.1 billion in 2019, becoming the second most disabling disease [ 1 ]. Until now, MA treatment focuses on symptomatic pain relief, which is only effective in 30–50% of the MA population [ 2 …]. To be noted, it is reported that patients with MA with patent foramen ovale (PFO) can achieve a radical cure of headache by blocking PFO [

  12. Open Access 01-12-2024 | Migraine | ReviewPaper

    Reconceptualizing autonomic function testing in migraine: a systematic review and meta-analysis

    The relation between autonomic nervous system (ANS) dysfunction and common headache disorders (including migraine [ 1 – 3 ], cluster headaches [ 4 ] and tension-type headaches [ 5 , 6 ]) has been widely documented. In migraine, a plethora of …

  13. 10-03-2024 | Fremanezumab | ReviewPaper

    Anti-calcitonin Gene-Related Peptide Monoclonal Antibodies in Migraine: Focus on Clinical Pharmacokinetics

    The calcitonin gene-related peptide transmission was the target for recent development of drugs that effectively prevent attacks of both episodic and chronic migraine. The aim of this narrative review was to offer deeper insight into …

  14. Open Access 01-12-2024 | Migraine | OriginalPaper

    Healthcare utilisation and economic burden of migraines among bank employees in China: a probabilistic modelling study

    Migraines stand as a significant and pressing public health concern [ 1 – 3 ], contributing to a substantial number of years lived with disability worldwide. This illness has consistently been identified in Global Burden of Disease studies as a …

  15. 08-03-2024 | Erenumab | ReviewPaper

    Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies in Migraine: Focus on Drug Interactions

    Calcitonin gene-related peptide neurotransmission was the target for recent development of monoclonal antibodies that effectively prevent attacks of both episodic and chronic migraine. The aim of this narrative review was to offer deeper insight …

  16. Open Access 01-12-2024 | Medication Overuse Headache | OriginalPaper

    Unsatisfactory response to acute medications does not affect the medication overuse headache development in pediatric chronic migraine

    Migraine is the primary cause of pain in childhood and its frequency increases with age, overtaking 20% in adolescence [ 1 ]. Throughout life, the frequency, severity, and disability of this condition can fluctuate. The transition between episodic …

  17. 16-04-2024 | Aura | Online First

    Alteration in the expression of long non-coding RNAs in the circulation of migraineurs

    Migraine is a complex disorder in terms of pathophysiology, since two contrasting opinions exist about the site of pain generation, i.e., peripheral vs. central in this condition. Migraine shares some features with neuropathic as well as …

  18. Open Access 12-04-2024 | Migraine | Online First

    Cognitive assessment during the phases of a spontaneous migraine: a prospective cohort study

    Cognitive dysfunction is the second most disabling symptom of a migraine attack, and is likely to be responsible for some of the significant economic burden of migraine [ 1 ]. Cognitive dysfunction is the most frequent symptom complex in the …

  19. Open Access 01-12-2024 | Migraine | OriginalPaper

    Dynamic fluctuations of salivary CGRP levels during migraine attacks: association with clinical variables and phenotypic characterization

    Migraine is a neurological disorder characterized by cyclic paroxysmal multiphase attacks of head pain and a myriad of neurological symptoms [ 1 ]. It is a prominent cause of disability due to its profound impact on individuals. The frequent …

  20. Open Access 01-12-2024 | Migraine | OriginalPaper

    Migraine treatment: quo vadis? Real-world data study (2015–2022) in Spain

    Migraine is a debilitating condition affecting over 14% of the global population [ 1 ]. It is the second leading cause of disability and the first among women aged between 15 and 49 years old [ 2 ]. The condition is typically classified as either …

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