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4395 search results for:

Pravastatin 

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  1. 01-04-2024 | Pravastatin | News

    Pravastatin

    Immune-mediated necrotising myopathy
  2. 01-04-2024 | Pravastatin | News

    Pravastatin

    Lack of efficacy
  3. 01-02-2024 | Pravastatin | News

    Pravastatin/TJ-68

    Biliary cholangitis-autoimmune hepatitis overlap syndrome
  4. 01-12-2023 | Pravastatin | News

    Pravastatin

    Lack of efficacy
  5. 01-09-2022 | Pravastatin | News

    Pravastatin

    Drug-induced liver injury : case report
  6. 01-08-2019 | Pravastatin | News

    Pravastatin/simvastatin

    Lipid storage myopathy secondary to multiple acyl-CoA dehydrogenases deficiency: 2 case reports
  7. 01-07-2019 | Pravastatin | News

    Pravastatin/rosuvastatin

    Various toxicities: 7 case reports
  8. Open Access 01-12-2019 | Pravastatin | OriginalPaper

    Diabetogenic effect of pravastatin is associated with insulin resistance and myotoxicity in hypercholesterolemic mice

    Statin therapy is effective for lowering cholesterol and decreasing cardiovascular mortality [ 1 ]. These drugs are among the most prescribed drugs in Western countries; they are taken by more than 25 million individuals worldwide [ 2 ]. Statins …

  9. Open Access 01-12-2019 | Infertility | OriginalPaper

    Pilot randomized trial of short-term changes in inflammation and lipid levels during and after aspirin and pravastatin therapy

    Low-grade inflammation is a condition in which the body produces low amounts of inflammatory factors for an extended period. Women with overweight/obesity often have both low-grade inflammation and elevated blood lipids, such as cholesterol and …

  10. 01-07-2021 | Pravastatin | News

    Pravastatin

    Acute pancreatitis: case report
  11. Open Access 01-03-2022 | Pravastatin | OriginalPaper

    Prediction of drug–drug interaction potential mediated by transporters between dasatinib and metformin, pravastatin, and rosuvastatin using physiologically based pharmacokinetic modeling

    Dasatinib is a tyrosine kinase inhibitor (TKI) approved for the treatment of adult patients with Philadelphia-positive (Ph +) chronic myeloid leukemia (CML) or Ph + acute lymphoblastic leukemia (ALL) with resistance or intolerance to prior …

  12. 01-02-2021 | Pravastatin | OriginalPaper

    Phase 2 trial comparing sorafenib, pravastatin, their combination or supportive care in HCC with Child–Pugh B cirrhosis

    Hepatocellular carcinoma (HCC) is the fourth cause of cancer death worldwide [ 1 ]. The mortality is rising in Western Countries [ 2 ]. Most HCC arise in patients with cirrhosis. In these patients, HCC and cirrhosis are both at risk of …

  13. 01-02-2021 | Pravastatin | OriginalPaper

    Evaluation of Pharmacokinetic Drug Interactions of the Direct-Acting Antiviral Agents Elbasvir and Grazoprevir with Pitavastatin, Rosuvastatin, Pravastatin, and Atorvastatin in Healthy Adults

    The introduction of direct-acting antiviral agents has revolutionized the treatment of hepatitis C virus (HCV) infection and offered the possibility of a sustained virologic response to the estimated 71 million people infected with HCV worldwide [ …

  14. Open Access 01-12-2020 | Coronary Heart Disease | OriginalPaper

    Doubly robust estimator of risk in the presence of censoring dependent on time-varying covariates: application to a primary prevention trial for coronary events with pravastatin

    Establishment of the long-term effectiveness of primary prevention treatments often requires large randomized controlled trials (RCTs) over a long time period. In such RCTs, survival functions and risks between randomized groups are compared using …

  15. Open Access 01-12-2019 | Pravastatin | OriginalPaper

    Pravastatin induces NO synthesis by enhancing microsomal arginine uptake in healthy and preeclamptic placentas

    Preeclamsia is a gestational disorder characterized by hypertension and proteinuria, and is one of the leading cause of maternal and fetal mortality affecting 2–8% of all pregnancies [ 1 , 2 ]. Since there have been no effective methods for its …

  16. 01-10-2018 | News

    Pravastatin/rosuvastatin

    Achilles tendon rupture and reproducible bilateral tendinopathy: case report
  17. 01-12-2018 | OriginalPaper

    Optimizing Lipid Pattern by Adding a Combined Nutraceutical or Pravastatin to Fenofibrate Treatment in Hypertriglyceridemic Subjects: Single Site, Randomized, Open-Label, Post-Market Clinical Investigation

    Hypertriglyceridemia is a risk factor for cardiovascular disease [ 1 ] and triglyceride-lowering treatments seems to (at least) partly reverse the added cardiovascular risk related to this parameter in hypertriglyceridaemic subjects [ 2 ]. In this …

  18. 01-06-2017 | OriginalPaper

    Effects of High-cholesterol Diet on Pravastatin Disposition in the Perfused Rat Liver

    Cholesterol homeostasis is maintained in the body through the modulation of cholesterol biosynthesis, intestinal absorption, and biliary excretion of bile acid. Cholesterol is important for maintaining the fluidity and permeability of cell …

  19. 01-01-2020 | BookReview

    Pravastatin kann strahleninduzierte Fibrosen im Kopf-Hals-Bereich reduzieren

    Radiogene fibrotische Veränderungen stellen eine unerfreuliche chronische Therapiefolge dar, und alle derzeit verfügbaren therapeutischen Maßnahmen sind dagegen nahezu wirkungslos. Präklinische biologische Modelle und klinische Studien …

  20. 01-04-2015 | News

    Pravastatin

    Subacute cutaneous lupus erythematosus: case report

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