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Nystagmus 

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  1. 03-04-2024 | Nystagmus | OriginalPaper

    Electroretinography in congenital nystagmus patients with a normal fundus examination

    Congenital nystagmus is a conjugate, involuntary horizontal oscillation of the eyes that usually presents during the first three months of life [ 1 ] and persists throughout life [ 2 ]. The intensity of congenital nystagmus may either increase or …

  2. Open Access 21-02-2024 | Downbeat Nystagmus | Letter

    RFC1 repeat expansions in downbeat nystagmus syndromes: frequency and phenotypic profile

    Until recently, the cause of downbeat nystagmus (DBN) has remained unknown (“idiopathic”) in approximately 30% of cases [ 1 ]. However, intronic FGF14 (GAA) ≥250 repeat expansions, known to cause spinocerebellar ataxia 27B/GAA- FGF14 disease [ 2 …

  3. 02-04-2024 | Nystagmus | Online First

    Subjective BPPV revisited: identification of positional nystagmus with a new maneuver

  4. Open Access 18-03-2024 | Nystagmus | Online First

    Effects of Baclofen on Central Paroxysmal Positional Downbeat Nystagmus

    Paroxysmal positional nystagmus frequently occurs in lesions involving the cerebellum, and has been ascribed to disinhibition and enhanced canal signals during positioning due to cerebellar dysfunction. This study aims to elucidate the mechanism …

  5. Open Access 18-03-2024 | Downbeat Nystagmus | Online First

    Gravity-Dependent Modulation of Downbeat Nystagmus and Subjective Visual Vertical in the Roll Plane

    Downbeat nystagmus (DBN) is the most common form of acquired central vestibular nystagmus. Gravity perception in patients with DBN has previously been investigated by means of subjective visual straight ahead (SVA) and subjective visual vertical …

  6. 29-03-2024 | Nystagmus | Online First

    Central paroxysmal positional nystagmus mimicking posterior canal benign paroxysmal positional vertigo in pontine infarction: a case report and literature review

  7. Open Access 01-02-2024 | Benign Paroxysmal Positional Vertigo | Online First

    Positional nystagmus is observed in the vast majority of healthy individuals

  8. 26-09-2023 | Nystagmus | Letter

    Conjugate torsional pendular nystagmus and palatal tremor after unilateral internuclear ophthalmoplegia

    Most patients with OPT show various patterns of horizontal gaze palsy from the acute event [ 3 ]. INO is a common preceding condition of OPT [ 5 , 6 ]. Our patient showed OPT subsequent to unilateral INO. He also showed the typical findings of INO …

  9. Open Access 01-12-2023 | Downbeat Nystagmus | OriginalPaper

    Vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin: a case report

    Vestibular epilepsy is defined as recurrent simple complex or partial seizures that cause vertigo as the predominant symptom [ 1 ]. Based on clinical observation, vertigo attacks seldom present as the sole clinical manifestation of epilepsy.

  10. Open Access 18-10-2023 | Nystagmus | Online First

    A Case of Anti-Ma2 Encephalitis Presenting with Pendular Torsional Nystagmus

    Antibodies against the neuronal protein Ma2 have been reported in a peculiar form of paraneoplastic encephalitis with prominent involvement of the limbic, brainstem, and diencephalic structures and usually associated with germ cell testicular …

  11. Open Access 01-12-2023 | OriginalPaper

    Smith-Kingsmore syndrome with nystagmus as the initial symptom

    Smith-Kingsmore syndrome (SKS) is a rare autosomal dominant disorder with de novo mutations of MTOR in most cases and germline mosaicism in a few cases. The first case was reported by Smith et al. in 2013 [ 1 ]. The incidence of SKS remains …

  12. Open Access 31-08-2023 | Nystagmus | OriginalPaper

    Capturing nystagmus during vertigo attacks using a smartphone: adherence, characteristics, pearls and pitfalls

    Dizziness and vertigo are frequently encountered symptoms in daily clinical practice, which might result from vestibular disorders [ 1 – 3 ]. These vestibular disorders are classified into acute, episodic, and chronic vestibular disorders [ 4 ].

  13. 15-12-2022 | Downbeat Nystagmus | OriginalPaper

    Generalized vestibular hyporeflexia and chronic upbeat nystagmus due to thiamine deficiency

    Technological advances in Vestibular Neurology in recent years identified new clinical signs among patients with Wernicke’s thiamine deficiency, not only contributing to the diagnosis of this highly treatable disorder but also contributing to our …

  14. 11-07-2022 | Vestibular Migraine | ReviewPaper

    Central Positional Nystagmus

    Central positional nystagmus (CPN) is characterized by nystagmus triggered by changes in head position, and is caused by cerebellar and/or brainstem disorders involving the central vestibulo-cerebellar pathways, either in a permanent or transient …

  15. 01-10-2022 | Spontaneous Nystagmus | Online First

    Factors associated with spontaneous nystagmus changes in acute Ménière’s disease

    In acute Ménière’s disease (MD), spontaneous nystagmus (SN) usually occurs with an initial ‘irritative’ beating toward the affected ear, and often changes direction reversely with decreased vestibular symptoms [ 1 ]. These findings characterize the …

  16. 27-10-2022 | Infertility | Letter

    Seizures and central vestibular nystagmus as the initial presentation of leukoencephalopathy with ataxia (LKPAT)

  17. 01-04-2022 | Spontaneous Nystagmus | ReviewPaper

    Central positional nystagmus: an update

    Clinically, central positional nystagmus (CPN) is often suspected when atypical forms of its peripheral counterpart, i.e., benign paroxysmal positional vertigo (BPPV), are observed, namely a linear horizontal nystagmus as in horizontal canal BPPV …

  18. 01-10-2021 | Gaze-Evoked Nystagmus | OriginalPaper

    Cerebellar Rebound Nystagmus Explained as Gaze-Evoked Nystagmus Relative to an Eccentric Set Point: Implications for the Clinical Examination

    A brain stem/cerebellar neural integrator enables stable eccentric gaze. Cerebellar loss-of-function can cause an inability to maintain gaze eccentrically (gaze-evoked nystagmus). Moreover, after returning gaze to straight ahead, the eyes may …

  19. 01-02-2023 | Upbeat Nystagmus | BriefCommunication

    Upbeat Nystagmus with an Unusual Velocity-Decreasing and Increasing Waveform: a Sign of Gaze-Holding Dysfunction in the Paramedian Tracts in the Medulla?

    We report a patient with spontaneous upbeat nystagmus (UBN) due to an ischemic lesion involving the paramedian tract (PMT) in the medulla. Eye movement recordings, using an infrared video-oculography (VOG) system, showed that the slow phase of the …

  20. Open Access 18-07-2022 | Stroke | OriginalPaper

    Capturing nystagmus in the emergency room: posterior circulation stroke versus acute vestibular neuritis

    Stroke accounts for 4–12% of vertigo and imbalance presentations to the emergency room (ER) and is often misdiagnosed [ 1 – 3 ]. Given the availability of reperfusion strategies, early diagnosis and treatment of posterior circulation stroke (PCS) …

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