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2250 search results for:

Ruxolitinib 

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  1. 01-05-2024 | Aspergillus Fumigatus | News

    Ruxolitinib

    Acute invasive fungal sinusitis secondary to Aspergillus niger, Aspergillus fumigatus and Aspergillus favus
  2. 01-05-2024 | Ruxolitinib | News

    Ruxolitinib

    Psoas muscle abscess caused by Mycobacterium tuberculosis
  3. 01-05-2024 | Ruxolitinib | News

    Ruxolitinib

    Various toxicities
  4. 01-04-2024 | Ruxolitinib | News

    Ruxolitinib

    Various toxicities
  5. 01-04-2024 | Ruxolitinib | News

    Ruxolitinib

    Pruritus and no response
  6. 01-04-2024 | Ruxolitinib | News

    Ruxolitinib

    Hypercalcaemia and drug withdrawal syndrome
  7. 01-04-2024 | Ruxolitinib | News

    Ruxolitinib

    Haemorrhage
  8. 01-04-2024 | Ruxolitinib | News

    Ruxolitinib

    Lack of efficacy
  9. 01-04-2024 | Ruxolitinib | News

    Ruxolitinib

    Pancytopenia
  10. 01-04-2024 | Ruxolitinib | News

    Ruxolitinib

    Lack of efficacy
  11. Open Access 13-03-2024 | Ruxolitinib | OriginalPaper

    Ruxolitinib Adherence in Myelofibrosis and Polycythemia Vera: the “RAMP” Italian multicenter prospective study

    Ruxolitinib is beneficial in patients with myelofibrosis (MF) and polycythemia vera (PV). Information on ruxolitinib adherence is scant. The Ruxolitinib Adherence in Myelofibrosis and Polycythemia Vera (RAMP) prospective multicenter study …

  12. 16-04-2024 | Ruxolitinib | Online First

    Ruxolitinib Cream 1.5%: A Review in Non-Segmental Vitiligo

    Topical ruxolitinib 1.5% cream (Opzelura®), a Janus kinase (JAK) inhibitor, is the first treatment to be approved in several countries for use in patients aged ≥ 12 years with non-segmental vitiligo. In the identical phase III TRuE-V1 and TRuE-V2 …

  13. Open Access 25-04-2024 | Ruxolitinib | Online First

    Hematocrit control and thrombotic risk in patients with polycythemia vera treated with ruxolitinib in clinical practice

    Polycythemia vera (PV) is a myeloproliferative neoplasm characterized by unregulated red blood cell production resulting in elevated hemoglobin and/or hematocrit levels. Patients often have symptoms such as fatigue, pruritus, and painful …

  14. Open Access 02-05-2024 | Ruxolitinib | Online First

    Efficacy, Safety, and Long-Term Disease Control of Ruxolitinib Cream Among Adolescents with Atopic Dermatitis: Pooled Results from Two Randomized Phase 3 Studies

    Atopic dermatitis (AD) is a highly pruritic, inflammatory skin disease [ 1 ] that typically begins in childhood. Globally, the prevalence of AD is approximately 7% in adolescents from 12 to < 18 years old, although reported rates vary [ 2 – 4 ]. AD …

  15. 01-03-2024 | Ruxolitinib | News

    Ruxolitinib

    Pneumonitis following drug withdrawal
  16. 20-04-2024 | Ruxolitinib | Online First

    A Phase I Trial Evaluating the Addition of Lenalidomide to Patients with Relapsed/Refractory Multiple Myeloma Progressing on Ruxolitinib and Methylprednisolone

    Multiple myeloma (MM) is a malignant neoplasm of terminally differentiated plasma cells within the bone marrow (BM) and accounts for 10% of all hematological malignancies as well as roughly 2% of all new cancer cases and related deaths [ 1 , 2 ].

  17. Open Access 01-12-2024 | Ruxolitinib | OriginalPaper

    Acute invasive fungal sinusitis with orbital tip syndrome in patients on long-term use of ruxolitinib: a case report

  18. Open Access 01-04-2024 | Ruxolitinib | OriginalPaper

    Ruxolitinib Improves Immune-Dysregulation Features but not Epigenetic Abnormality in a Patient with STAT1 GOF

    Janus kinase (JAK)-signal transducer of activators of transcription (STAT) pathways play crucial roles in the intracellular signal transduction of various cytokines, including interferons (IFNs) [ 1 – 4 ]. Genetic mutations in JAK-STAT-related …

  19. Open Access 01-04-2024 | Ruxolitinib | OriginalPaper

    Patients with STAT1 Gain-of-function Mutations Display Increased Apoptosis which is Reversed by the JAK Inhibitor Ruxolitinib

    Heterozygous signal transducer and activator of transcription 1 ( STAT1 ) gain-of-function (GOF) mutations have been discovered in 2011 [ 1 , 2 ] as the cause of most inherited chronic mucocutaneous candidiasis (CMC), but follow-up studies have …

  20. Open Access 08-03-2024 | Ruxolitinib | OriginalPaper

    Satisfaction with Control of Mild to Moderate Atopic Dermatitis with Ruxolitinib Cream: US Physician and Patient Perspectives

    Atopic dermatitis (AD) is a chronic, relapsing, inflammatory skin disease characterized by itchy, scaly, painful skin that frequently results in sleep disturbances and can greatly impact patients’ work productivity and quality of life [ 1 – 8 ].

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