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12421 search results for:

Sarcoidosis 

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  1. Open Access 08-05-2024 | Sarcoidosis | Online First

    Insights of Inflammatory Heart Involvement in Cardiac Sarcoidosis – A Systemic Review

    Sarcoidosis is a systemic inflammatory disease, and cardiac involvement is the most frequent cause of death from this condition [ 1 ]. While the majority of cases with systemic sarcoidosis show a self-limiting process that only affects the lung and …

  2. Open Access 01-12-2024 | Sarcoidosis | OriginalPaper

    Choroidal manifestations of non-ocular sarcoidosis: an enhanced depth imaging OCT study

    Sarcoidosis is a chronic multisystem disorder of unknown origin defined by non-caseating granulomas with the accumulation of T-lymphocytes [ 1 ]. Although the most commonly affected organs are the lungs and intrathoracic lymph nodes, almost any …

  3. Open Access 01-12-2024 | Sarcoidosis | ReviewPaper

    Diagnostic delay of sarcoidosis: an integrated systematic review

    Sarcoidosis is a multisystem granulomatous inflammatory disease of unknown cause, which can affect any organ, but primarily affects the lungs. Sarcoidosis can present as acute or chronic disease - acute sarcoidosis, with joint pain, erythema …

  4. Open Access 24-04-2024 | Sarcoidosis | Online First

    Role of triglyceride-glucose index in metabolic assessment of sarcoidosis patients

    Sarcoidosis is a rare granulomatous disease that can affect any organ. It leads to an increased risk of metabolic syndrome and insulin resistance, due to biochemical pathways involved in low-grade inflammation in both diseases. The aim of our …

  5. Open Access 01-12-2024 | Sarcoidosis | OriginalPaper

    Microblading reaction as a manifestation of systemic sarcoidosis: two case reports and a review of the literature

    Sarcoidosis is a complex disease with unknown etiology and pathogenesis. Several factors may contribute to the development of sarcoidosis, such as a genetic predisposition with certain human leukocyte antigen (HLA) genotypes [ 1 ] and/or …

  6. 29-04-2024 | Cardiac Amyloidosis | Online First

    Nuclear medicine practice for the assessment of cardiac sarcoidosis and amyloidosis. A survey endorsed by the EANM and EACVI.

    Cardiac amyloidosis (CA) is an infiltrative and restrictive cardiomyopathy that might rapidly lead to heart failure if left untreated. The prognosis is variable and depends on the type of cardiac amyloidosis, but the end stages are associated with …

  7. Open Access 01-12-2024 | Sarcoidosis | OriginalPaper

    Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosis

    Sarcoidosis is a systemic granulomatous disease of unknown cause mainly affecting the lungs, intrathoracic lymph nodes, eyes and skin [ 1 ]. Diagnosis, monitoring, as well as predicting disease course or response to therapy is challenging in the …

  8. Open Access 01-12-2024 | Sarcoidosis | OriginalPaper

    Increased proportions of circulating PD-1+ CD4+ memory T cells and PD-1+ regulatory T cells associate with good response to prednisone in pulmonary sarcoidosis

    Sarcoidosis is a granulomatous multi-organ disease with variable disease course. The majority of patients presents with pulmonary involvement [ 1 ]. The decision to initiate treatment for sarcoidosis is based on an individual assessment of …

  9. 02-03-2024 | Sarcoidosis | OriginalPaper

    The active papillary muscle sign in 18F-FDG PET/CT cardiac sarcoidosis exams and its relationship with myocardial suppression

    18 Fluorodeoxyglucose positron emission tomography ( 18 F-FDG-PET/CT) is an important molecular imaging method used in the diagnosis of cardiac sarcoidosis (CS) along with magnetic resonance imaging (MRI). 18 F-FDG-PET/CT can detect the active …

  10. 20-01-2024 | Sarcoidosis | ReviewPaper

    Hepatic Sarcoidosis: A Review of the Diagnosis and Management

    Sarcoidosis is a systemic inflammatory disease characterized by the formation of granulomas, most commonly in the lungs and hilar lymph nodes. However, extrapulmonary disease occurs in 30–50% of cases with the liver, skin, and eyes being the most …

  11. 08-03-2024 | Sarcoidosis | Online First

    A Case of Unilateral Vision Loss Due to Optic Disc Infiltration by Sarcoidosis

    Sarcoidosis is a multisystem disorder characterized by the development of non-caseating granulomas in various organ systems. Women aged 25–29 years and 65–69 years are most prevalently diagnosed with sarcoidosis, 1 and clinical manifestations vary …

  12. Open Access 12-01-2024 | Sarcoidosis | OriginalPaper

    Menopausal hormone therapy and risk of sarcoidosis: a population-based nested case–control study in Sweden

    Sarcoidosis incidence peaks in women between 50 and 60 years old, which coincides with menopause, suggesting that certain sex hormones, mainly estrogen, may play a role in disease development. We investigated whether menopausal hormone therapy …

  13. Open Access 01-12-2024 | Infliximab | OriginalPaper

    Efficacy and safety of Infliximab in systemic sarcoidosis according to GenPhenReSa organ-involvement phenotype: a retrospective study of 55 patients

    Sarcoidosis is a systemic granulomatous disease that can potentially lead to serious complications when affecting crucial organs, such as the brain, heart, lungs, kidneys, liver, or eyes. It is a great mimicker [ 1 ] in medicine, and complications …

  14. 04-11-2023 | Sarcoidosis | OriginalPaper

    STAT expression and TFH1 cells in CVID granulomatosis and sarcoidosis: immunological and histopathological comparisons

    Granulomatous disease is a serious complication of common variable immunodeficiency (CVID-GD) that occurs in 8–22% of these patients and can mimic sarcoidosis, with which it shares certain clinical, biological, and radiological features. However …

  15. 01-02-2024 | OriginalPaper

    Improvement of liver histology in hepatic sarcoidosis due to treatment with corticosteroids and ursodeoxycholic acid: a case report

    We report the case of a 48-year-old male with a history of pulmonary and ocular sarcoidosis. Non-caseating granulomas, identified histologically, are the most characteristic manifestation of sarcoidosis. Hepatic sarcoidosis is difficult to …

  16. 16-12-2023 | Denosumab | OriginalPaper

    Efficacy of denosumab in the treatment of hypercalcemic renal dysfunction in sarcoidosis: a case report

    A 70-year-old female patient was admitted for close examination and treatment of hypercalcemia (corrected serum calcium levels: 3.04 mmol/L) and renal dysfunction (serum creatinine levels: 254.59 µmol/L). The patient had a history of sarcoidosis

  17. Open Access 01-12-2024 | Sarcoidosis | OriginalPaper

    Blood glucose and lipids are associated with sarcoidosis: findings from observational and mendelian randomization studies

    Sarcoidosis is a multiple systemic granulomatous inflammation disease with unknown etiology to date, characterized by abnormal immune response to unidentified antigens [ 1 ]. Regardless of the variable morbidity in different races (highest in …

  18. Open Access 16-03-2024 | Sarcoidosis | Online First

    Machine learning approach using 18F-FDG-PET-radiomic features and the visibility of right ventricle 18F-FDG uptake for predicting clinical events in patients with cardiac sarcoidosis

    Sarcoidosis is a systemic granulomatous inflammatory disease of unknown etiology. Cardiac involvement is clinically rare, and it only occurs in 5% of patients with sarcoidosis [ 1 , 2 ]. However, cardiac sarcoidosis (CS) is an important predictor …

  19. Open Access 04-11-2023 | Hypersensitivity Pneumonitis | OriginalPaper

    Concurrent features of sarcoidosis and hypersensitivity pneumonitis in two patients exposed to fungal antigens

    Two patients presented with concomitant features of sarcoidosis and hypersensitivity pneumonitis, suggesting a common biologic background, at least in some cases.

  20. 14-11-2023 | OriginalPaper

    An Artificial Intelligence Platform for the Radiologic Diagnosis of Pulmonary Sarcoidosis: An Initial Pilot Study of Chest Computed Tomography Analysis to Distinguish Pulmonary Sarcoidosis from a Negative Lung Cancer Screening Scan

    The lung is the most common organ involved with sarcoidosis with a frequency of 90 percent in most series [ 1 , 2 ]. In addition, pulmonary sarcoidosis is problematic to diagnose, with an average delay of 3 months between symptom onset and …

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