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Thrombocytopenia 

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  1. 29-04-2024 | Thrombocytopenia | Online First

    Post-transfusion purpura and adult primary thrombocytopenia

  2. Open Access 07-05-2024 | Thrombocytopenia | Online First

    Risk Factors of Chemotherapy-Induced Thrombocytopenia After Oxaliplatin-Containing Chemotherapy for Gastrointestinal Malignancies

    Cancer is a major threat to human health, and there are ~ 19.3 million individuals diagnosed with cancer and 1 million cancer-related deaths per year globally [ 1 ]. Despite the rapid development of new anti-cancer treatments in recent years, such …

  3. Open Access 01-12-2024 | Thrombocytopenia | OriginalPaper

    A 11-year-old boy with Blastocystis hominis infection, presents as immune thrombocytopenia

    Immune thrombocytopenia (ITP) is an acquired autoimmune disease characterized by low platelet counts (< 100 × 10 9 /L) and an increased risk of bleeding [ 1 ]. First-line therapy for ITP is are corticosteroids and intravenous immunoglobulins [ 2 ].

  4. Open Access 01-12-2024 | Thrombocytopenia | OriginalPaper

    Computer-aided designing of a novel multi‑epitope DNA vaccine against severe fever with thrombocytopenia syndrome virus

    Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne viral disease caused by the SFTS virus (Dabie bandavirus), which has become a substantial risk to public health. No specific treatment is available now, that calls for an …

  5. Open Access 26-04-2024 | IgA Vasculitis | Online First

    Mendelian randomization reveals association of gut microbiota with Henoch–Schönlein purpura and immune thrombocytopenia

    Gut microbiota have been linked to immune thrombocytopenia (ITP) and Henoch–Schönlein purpura (HSP) in recent studies, but a cause-and-effect relationship is unclear. We used Mendelian randomization (MR) to assess causal relationships between gut …

  6. 23-04-2024 | SARS-CoV-2 | Online First

    SARS-CoV-2 infection-induced immune thrombocytopenia: a systematic review of current reports

    Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a low platelet count with increased risk of bleeding, and viral infection may trigger ITP. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-induced ITP …

  7. 29-04-2024 | Thrombocytopenia | Online First

    Prediction Model for Severe Thrombocytopenia Induced by Gemcitabine Plus Cisplatin Combination Therapy in Patients with Urothelial Cancer

    Severe thrombocytopenia is often induced by combination therapy using gemcitabine and cisplatin (GC). Grade 3 or 4 thrombocytopenia was more frequent in patients receiving GC therapy than in those receiving methotrexate, vinblastine, doxorubicin …

  8. 24-04-2024 | Thrombocytopenia | Online First

    Outcomes of mechanical thrombectomy in patients with acute ischemic stroke and thrombocytopenia: systematic review and meta-analysis

    Multiple randomized controlled trials have demonstrated the benefit of mechanical thrombectomy (MT) over medical therapy in patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO). Yet, AIS continues to be a global leading …

  9. 27-03-2024 | Thrombocytopenia | OriginalPaper

    Herombopag for the treatment of persistent thrombocytopenia following hematopoietic stem cell transplantation

    Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) stands as a pivotal treatment for hematologic malignancies, often considered the sole effective treatment option. A frequent complication following allo-HSCT is poor graft function …

  10. Open Access 14-03-2024 | Linezolid | OriginalPaper

    Linezolid-Induced Thrombocytopenia in Patients with Renal Impairment: A Case Series, Review and Dose Advice

    Linezolid is a synthetic antibacterial agent from the class of oxazolidinones. It is effective against most Gram-positive bacteria including methicillin-resistant Staphylococcus aureus, penicillin-resistant Streptococcus pneumoniae and …

  11. Open Access 01-12-2024 | Aortic Valve Replacement | OriginalPaper

    Thrombocytopenia after sutureless and standard stented aortic valve replacement: a retrospective analysis of risk factors, clinical course, and early outcome

    The aetiology of thrombocytopaenia post aortic valve replacement (AVR) with the Perceval sutureless valve (Corcym Canada Corp, Burnaby, BC, Canada) has been long debated. One randomised trial and several small cohort studies comparing the Perceval …

  12. 20-04-2024 | Rituximab | Online First

    Clinical Profile, Treatment and Outcome of Thrombotic Thrombocytopenia Purpura (TTP) in Rituximab Era- an Experience from Tertiary Care Centre from North India

    Thrombotic thrombocytopenic purpura (TTP) is a microangiopathic hemolytic anemia (MAHA) resulting from severe deficiency of ADAMTS13. TTP is an acute medical emergency which requires early treatment with therapeutic plasma exchange. With the early …

  13. 25-03-2024 | COVID-19 | OriginalPaper

    The evolution of preexisting primary immune thrombocytopenia after COVID-19 onset: A nationally representative, prospective, multicentre, observational study

    The symptoms in patients with primary immune thrombocytopenia (ITP) after COVID-19 onset remain largely unclear. The aim of this study was to describe the platelet count fluctuations in ITP patients following the diagnosis of COVID-19. A …

  14. Open Access 22-01-2024 | Lymphoma | OriginalPaper

    Acute Thrombocytopenia Complicating the Initial Administration of Obinutuzumab: Is It More Frequent Than We Think?

    A case series of three patients suggests that obinutuzumab-induced acute thrombocytopenia is a frequent, possibly non-relapsing, and unique adverse event that deserves more attention than it currently receives.

  15. Open Access 01-12-2024 | Thrombocytopenia | OriginalPaper

    Can low-dose intravenous immunoglobulin be an alternative to high-dose intravenous immunoglobulin in the treatment of children with newly diagnosed immune thrombocytopenia: a systematic review and meta-analysis

    Intravenous immunoglobulin (IVIg) is a first-line treatment for children with newly diagnosed immune thrombocytopenia (ITP). Higher doses of IVIg are associated with a more insupportable financial burden to pediatric patients’ families and may …

  16. Open Access 01-12-2024 | Myocarditis | OriginalPaper

    Clinical characteristics and influencing factors of severe fever with thrombocytopenia syndrome complicated by viral myocarditis: a retrospective study

    Severe fever with thrombocytopenia syndrome (SFTS) is a zoonotic infectious disease caused by the SFTS virus (SFTSV) infection. SFTSV was first isolated and diagnosed from patient serum by Chinese researchers around 2010 [ 1 , 2 ]. From then until …

  17. 12-01-2024 | Carotid Endarterectomy | Letter

    Bolus-only bivalirudin for carotid endarterectomy in a patient with heparin-induced thrombocytopenia

  18. Open Access 01-12-2024 | Thrombocytopenia | OriginalPaper

    Antiphospholipid antibodies as potential predictors of disease severity and poor prognosis in systemic lupus erythematosus-associated thrombocytopenia: results from a real-world CSTAR cohort study

    Systemic lupus erythematosus (SLE) is a chronic complex systemic autoimmune disease involving multiple organs with multiple autoantibodies. Thrombocytopenia (TP) is a common clinical haematological abnormality, which is also known as one of the …

  19. 20-10-2023 | Thrombocytopenia | OriginalPaper

    Pretreatment Absolute Immature Platelet Count is a Promising Predictor of Response to Short-Term Dexamethasone Monotherapy or Combination Therapy in Newly Diagnosed Adult Primary Immune Thrombocytopenia

    Reliable indicators that can predict drug responsiveness in primary immune thrombocytopenia (ITP) patients are urgent. We aimed to establish a reference interval of percentage of immature platelet fraction (IPF%) and absolute immature platelet …

  20. 08-01-2024 | Thrombocytopenia | Letter

    What really matters with thrombocytopenia: absolute value, timing, etiology or management? Author's reply

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