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IPF patients report cough relief with morphine

PACIFY-COUGH results support the use of low-dose, controlled-release morphine to ease cough symptoms in patients with idiopathic pulmonary fibrosis.

Editor's Choice

Chronic cough as a genetic neurological disorder? Insights from CANVAS

Open Access Cough Review

Current thinking on the mechanisms underlying chronic cough, and how this might fit with the existence of cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS), a genetically driven disorder that has cough as a frequent feature.

Assessment and management of cough in IPF

A guide to evaluating and managing cough in people with idiopathic pulmonary fibrosis, as well as a discussion of emerging pharmacologic and nonpharmacologic approaches targeting the cough reflex.

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Case Studies

Plastic bronchitis associated with respiratory syncytial virus infection

Open Access Childhood Bronchitis Case Study

RSV has rarely been reported as an etiological agent for plastic bronchitis, but should be considered if hypoxemia is unresponsive to mechanical ventilation and ECMO.

Current Reviews

Predictive Factors for Successful Decannulation in Patients with Tracheostomies and Brain Injuries: A Systematic Review

Open Access Tracheostomy Review

Neurological patients frequently have disorders of consciousness, swallowing disorders, or neurological states that are incompatible with extubation. Therefore, they frequently require tracheostomies during their stay in an intensive care unit.

Chronic cough: more than just a persistent cough: a systematic literature review to understand the impact of chronic cough on quality of life

Cough Review

Cough is an essential reflex mechanism to prevent aspiration and enhance airway clearance [ 1 , 2 ]. However, excessive and prolonged cough may occur when the defense mechanism function of cough has been impaired [ 1 ]. In such cases, cough can be …

Mucus Transpiration as the Basis for Chronic Cough and Cough Hypersensitivity

Cough STATE OF THE ART REVIEW

Chronic cough is characterized by a state of cough hypersensitivity. We analyze the process of transpiration, by which water appears to evaporate from laryngeal and tracheal mucus as from the surface of a leaf, as a potential cause of cough …

The Therapeutic Landscape in Chronic Cough

Open Access Cough STATE OF THE ART REVIEW: THE THERAPEUTIC LANDSCAPE IN CHRONIC COUGH

In recent years, there has been a substantial increase in the development of antitussive therapies and the first new therapy, gefapixant has been licenced in Europe. This review describes current unlicenced treatments for chronic cough and details …

Further Reading

Tolerability of Antihypertensive Medications: The Influence of Age

Open Access Cough Original article

Hypertension represents one of the leading modifiable risk factors for cardiovascular morbidity and mortality, affecting more than 1.28 billion adults worldwide with increasing prevalence in advancing age [ 1 ]. Recent literature has provided clear …

Rasch validation of the short form (8 item) PC-QoL questionnaire and applicability of use as a health state classification system for a new preference-based measure

Open Access Cough

Chronic cough (lasting more than four weeks) in children is an important issue in healthcare because it may be a sign of underlying disease and is a common reason for parents to seek medical assistance. Evidence-based guidelines advocate …

First Exploration of the Altered Microbial Gut–Lung Axis in the Pathogenesis of Human Refractory Chronic Cough

Open Access Cough MICROBIOME AND COUGH

Chronic cough, that is a cough lasting longer than eight weeks, is among the most common respiratory symptoms for which patients seek medical advice [ 1 ]. It has long been recognized that virtually all diseases of the respiratory tract, as well as …