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Intensive Care Therapy 

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  1. 21-05-2024 | Central Nervous System Trauma | Online First

    European Society of Intensive Care Medicine clinical practice guideline on fluid therapy in adult critically ill patients. Part 1: the choice of resuscitation fluids

    Administration of resuscitation fluids is common in the management of critically ill patients [ 1 ]. The European Society of Intensive Care Medicine (ESICM) convened a group of content and method experts to issue a clinical practice guideline (CPG) …

  2. Open Access 01-12-2024 | ReviewPaper

    Conservative versus liberal oxygen therapy for intensive care unit patients: meta-analysis of randomized controlled trials

    Oxygen is essential for human survival and plays a crucial role in a wide range of physiological processes [ 1 ]. Oxygen therapy is among the most common interventions in critical illnesses [ 2 ]. However, excessive oxygenation can enhance the …

  3. 27-04-2024 | Carbapenem Antibiotic | Online First

    Evolution, control and success of combination therapy with Ampicilin-sulbactam/Ceftazidime-Avibactam during a Carbapenem-Resistant Acinetobacter baumannii outbreak in burn Intensive Care Unit

    We present our findings on interpatient transmission, epidemic control measures, and the outcomes of a series of ten critically ill burn patients who were either colonized or infected with carbapenem-resistant Acinetobacter baumannii (CRAB). None …

  4. Open Access 08-11-2023 | Anxiety | OriginalPaper

    Implementation feasibility of animal-assisted therapy in a pediatric intensive care unit: effectiveness on reduction of pain, fear, and anxiety

    Relationships between humans and animals, especially dogs, have been documented for thousands of years. The first evidence of canine domestication dates from around 12,000 years ago [ 1 ]. Several articles to date have examined the interactions …

  5. Open Access 04-10-2023 | Behavioural Therapy | OriginalPaper

    Feasibility and Efficacy of Intensive Dialectical Behavior Therapy Skills Training in An Outpatient Setting for A Group of Patients with Extensive Care Needs - A Transdiagnostic Approach

  6. Open Access 28-02-2023 | Care | OriginalPaper

    Intensive care drug therapy and its potential adverse effects on blood pressure and heart rate in critically ill children

    Patients treated in a pediatric intensive care unit (PICU) often have a complex medical history, a severe underlying disease, or are in an acute life-threatening condition [ 1 , 2 ]. Therefore, they usually need comprehensive drug therapy, which …

  7. Open Access 27-07-2023 | Acute Kidney Injury | OriginalPaper

    Development and validation of a nomogram to predict the risk of renal replacement therapy among acute kidney injury patients in intensive care unit

    The incidence of acute kidney injury (AKI) in intensive care unit (ICU) occurs in approximately 50% of critically ill patients [ 1 ]. The reason for AKI is often multi-factorial and complicated. If the renal injury cannot be reversed, then renal …

  8. Open Access 01-12-2023 | Septicemia | OriginalPaper

    Empiric antimicrobial therapy in the intensive care unit based on the risk of multidrug-resistant bacterial infection: a single-centre case‒control study of blood culture results in Japan

    Although intensive care unit (ICU) beds in many hospitals account for less than 10% of all hospital beds, more than 20% of all hospital-acquired infections (HAIs) occur in the ICU [ 1 ]. Infections and sepsis are the leading causes of death and …

  9. Open Access 01-12-2023 | Acute Pancreatitis | Erratum

    Correction: Intravenous fluid therapy in patients with severe acute pancreatitis admitted to the intensive care unit: a narrative review

  10. Open Access 01-12-2023 | Insulins | OriginalPaper

    Insulin therapy and blood glucose management in critically ill patients: a 1-day cross-sectional observational study in 69 French intensive care units

    Hyperglycaemia is common in critically ill patients due to increased hepatic output and decreased peripheral glucose uptake as a result of stress, inflammation and the associated decreased insulin sensitivity combined with elevated production of …

  11. 14-03-2022 | Ultrasound | OriginalPaper

    Doppler ultrasound in the assessment of renal perfusion before and during continuous kidney replacement therapy in the pediatric intensive care unit

    Pediatric patients requiring critical care are at risk of developing acute kidney injury (AKI). One of the cornerstones in the management of AKI is to reverse the cause of AKI and ensure appropriate perfusion to the kidneys to prevent further …

  12. Open Access 01-12-2023 | Care | OriginalPaper

    Medication administration errors in the domain of infusion therapy in intensive care units: a survey study among nurses

    Worldwide, medication errors are a major cause of injury and avoidable harm in healthcare with estimated costs of 42 billion US Dollars annually [ 1 ]. Medication errors are rated as one of the highest causes of death and are considered among the …

  13. Open Access 01-06-2021 | Pancreas Transplantation | OriginalPaper

    Donor insulin therapy in intensive care predicts early outcomes after pancreas transplantation

    Diabetes mellitus is a disease associated with high risks for morbidity and mortality due to multi-system micro- and macro-vascular complications. Pancreas transplantation (simultaneous pancreas and kidney, pancreas after kidney or pancreas …

  14. 01-09-2021 | Obesity | Original Research

    A Survey of Primary Care Practices on Their Use of the Intensive Behavioral Therapy for Obese Medicare Patients

    In 2011 and 2015, the Centers for Medicare and Medicaid Services (CMS) approved reimbursement to primary care providers (PCPs) under two procedure codes (G0447 and G0473) for providing intensive behavior therapy (IBT) for obese Medicare …

  15. 01-10-2020 | Central Nervous System Trauma | OriginalPaper

    Personalized Connectome Mapping to Guide Targeted Therapy and Promote Recovery of Consciousness in the Intensive Care Unit

    There are currently no therapies proven to promote early recovery of consciousness in patients with severe brain injuries in the intensive care unit (ICU). For patients whose families face time-sensitive, life-or-death decisions, treatments that …

  16. 01-09-2019 | ReviewPaper

    Mesenchymal Stem/Stromal Cell Therapy for Bronchopulmonary Dysplasia in the Neonatal Intensive Care Unit

    The field of neonatology has evolved rapidly over recent decades, resulting in improved infant outcomes and lowered gestational age of viability. While there have been significant improvements in survival rates for infants born less than 28 weeks’ …

  17. Open Access 01-12-2022 | Care | OriginalPaper

    Comorbidities and COVID-19 status influence the survival rate of geriatric patients in intensive care units: a prospective cohort study from the Indonesian Society of Anaesthesiology and Intensive Therapy

    Each year, medical technology develops tremendously as diseases management becomes more effective and comprehensive. Unfortunately, this revelation could appear as a double-edged sword to the world of medicine. The bright side is that many people …

  18. Open Access 01-12-2022 | Piperacillin | OriginalPaper

    Beta-lactam dosing during continuous renal replacement therapy: a survey of practices in french intensive care units

    Beta-lactams are the most widely prescribed antibiotics in critically ill patients. Optimized dosing of beta-lactams is required to deal with pharmacokinetic changes and frequent underdosing – especially during the early phase of sepsis [ 1 – 3 ].

  19. Open Access 01-12-2022 | Acute Liver Failure | OriginalPaper

    Adverse events, short- and long-term outcomes of extra corporeal liver therapy in the intensive care unit: 16 years experience with MARS® in a single center

    Extra corporeal organ support devices have been developed during the last century to compensate for function loss in case of organ failure. Unlike renal replacement therapy, liver support therapy development has faced difficulties regarding the …

  20. Open Access 01-12-2022 | Acute Kidney Injury | OriginalPaper

    The association between continuous renal replacement therapy as treatment for sepsis-associated acute kidney injury and trend of lactate trajectory as risk factor of 28-day mortality in intensive care units

    Sepsis is a common clinical critical illness [ 1 ] that causes dysfunction of the immune and blood coagulation systems, and affected patients usually have insufficient tissue perfusion [ 2 ]. As a product of glycolysis, lactate capacity directly …

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