Autoimmune encephalitis is increasingly recognized as a treatable type of encephalitis in children. Early immunotherapy improves motor outcomes, but less is known about long-term management and treatment for relapsing disease.
In the most common subtypes of autoimmune limbic encephalitis, existing biomarkers often display unspecific and subtle changes. But [18F]DPA-714-PET-MRI shows potential as a direct imaging marker of neuroinflammation.
About half of patients with autoimmune encephalitis experience movement disorders. Prompt identification and management of these disorders can improve diagnosis and prognosis of the encephalitis.
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Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
In the most common subtypes of autoimmune limbic encephalitis, existing biomarkers often display unspecific and subtle changes. But [18F]DPA-714-PET-MRI shows potential as a direct imaging marker of neuroinflammation.
Mpox infection can have a range of symptoms, including CNS complications such as seizures, confusion, and encephalitis. In this case, PCR of the CSF was negative for the virus, but intrathecal antibody production confirmed the diagnosis.
A 45-year-old man with ulcerative colitis presented with progressive cognitive impairment, quadriplegia, and disturbance of consciousness and gait, leading to a diagnosis of Bickerstaff's brainstem encephalitis.
Anti-N-methyl-D-aspartate receptor (NMDAr) autoimmune encephalitis (AE) is one of the most common causes of noninfectious encephalitis during pregnancy [ 1 – 3 ]. It is characterized by an autoimmune response against the NR1 subunit of NMDAr, which …
Neurotropic viruses may cause meningitis, myelitis, encephalitis, or meningoencephalitis. These inflammatory conditions of the central nervous system (CNS) may have serious and devastating consequences if not treated adequately. In this review, we …
With the increase in the number of cases of autoimmune encephalitis (AE), the cerebrospinal fluid (CSF) of people living with HIV (PLWH) showing abnormal behavior, cognitive impairment or abnormal movements should be actively screened for the …
Measles inclusion-body encephalitis (MIBE) is rare, with insights largely from case studies. We systematically analyzed subacute Sclerosing Panencephalitis (SSPE) cases in immunocompromised patients, identifying distinctive clinical and …
Neuroimaging plays an increasingly critical role in clinical practice. PET Pearls is an interactive activity designed to improve your confidence and accuracy when interpreting imaging for early signs of cognitive impairment.
Anti-N-methyl-D-aspartate receptor (NMDAr) autoimmune encephalitis (AE) is one of the most common causes of noninfectious encephalitis during pregnancy [ 1 – 3 ]. It is characterized by an autoimmune response against the NR1 subunit of NMDAr, which …
Since the zoonotic potential of Borna disease virus 1 (BoDV-1) was proven in 2018 [ 1 , 2 ], approximately 50 human cases within endemic regions in southern and eastern Germany have been reported to German health authorities [ 3 ]. Infections lead …
With the increase in the number of cases of autoimmune encephalitis (AE), the cerebrospinal fluid (CSF) of people living with HIV (PLWH) showing abnormal behavior, cognitive impairment or abnormal movements should be actively screened for the …
Autoimmune encephalitis is a relatively novel nosological entity characterized by an immune-mediated damage of the central nervous system. While originally described as a paraneoplastic inflammatory phenomenon affecting limbic structures, numerous …
