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Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
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Pediatrics
Open Access Endoscopic Retrograde Cholangiopancreatography Case Study

ERCP in a low-weight infant with obstruction jaundice

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Endoscopic retrograde cholangiopancreatography is used extensively in pediatric patients for diagnosing and treating biliary and pancreatic diseases, but is challenging in infants. Could this technique help?

Editor's Choice

Perforated appendicitis: room for improvement?

Free for a limited time Appendicitis Review

Appendicitis has been described for over 300 years, but care practices vary widely. Explore the risk factors for perforated appendicitis in children and recommendations for surgical and antimicrobial management.

Embryo transfer may increase risk for childhood leukemia

08-05-2024 Assisted Reproduction News

A French cohort study has found a significantly increased risk for leukemia in children born after fresh or frozen embryo transfer versus those conceived naturally.

Novel technique to secure IV catheters reduces failure rates

03-05-2024 Pediatric Emergency Medicine News

Using integrated securement dressings and tissue adhesive to secure peripheral intravenous catheters significantly reduces the likelihood of device failure in hospitalized children.

CHANTER syndrome from fentanyl exposure in a young child

Open Access Cerebral Edema Case Study

Cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome is a rare disorder associated with opioid neurotoxicity and almost exclusively seen in adults.

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Latest News

Embryo transfer may increase risk for childhood leukemia

08-05-2024 Assisted Reproduction News

Novel technique to secure IV catheters reduces failure rates

03-05-2024 Pediatric Emergency Medicine News

An alternative to venous neonatal blood draw?

26-04-2024 Whole Blood Values in Children News

Benefits of newborn screening for SMA

24-04-2024 Spinal Muscular Atrophy News

Lower heritability of adult-onset versus childhood-onset type 1 diabetes

23-04-2024 Type 1 Diabetes News

Teen pregnancy is a marker of premature mortality

17-04-2024 Pregnancy News
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on sleep in brain health

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Live event concluded

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.

On-demand video coming soon

Dr. Rolf Fronczek
Dr. Renata Riha
Dr. Sven Rupprecht
Developed by: Springer Medicine

Case Studies

ERCP in a low-weight infant with obstruction jaundice

Open Access Endoscopic Retrograde Cholangiopancreatography Case Study

Endoscopic retrograde cholangiopancreatography is used extensively in pediatric patients for diagnosing and treating biliary and pancreatic diseases, but is challenging in infants. Could this technique help?

CHANTER syndrome from fentanyl exposure in a young child

Open Access Cerebral Edema Case Study

Cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome is a rare disorder associated with opioid neurotoxicity and almost exclusively seen in adults.

Siblings with familial chylomicronemia syndrome

Open Access Hypertriglyceridemia Case Study

Familial chylomicronemia syndrome is a monogenic form of severe hypertriglyceridemia that increases the risk of pancreatitis. In this case, two brothers had familial chylomicronemia syndrome caused by rare GPIHBP1 deletions.

Current Reviews

Beyond Obesity and Overweight: the Clinical Assessment and Treatment of Excess Body Fat In Children

Obesity Review

This article is a continuation of Part 1 where we discussed insulin resistance as the primary driver of medical obesity and the cardiometabolic sequelae. Insulin resistance has two essential components. The first is the insulin resistance itself …

Beyond Obesity and Overweight: The Clinical Assessment and Treatment of Excess Body Fat in Children

Obesity Review

Pediatric obesity rates and weight-related comorbidities continue to rise despite increasing awareness. Nationally, the obesity rates among 20–39-year-olds is approximately 40%, as reported by the CDC [ 1 ]; this is a 300% increase since the 1970s …

Adis Summary of Research: Extended‑Release Viloxazine Compared with Atomoxetine for Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder Adis Summary of Research

In patients with attention deficit hyperactivity disorder (ADHD), norepinephrine reuptake inhibitors like atomoxetine may show mild effectiveness in addressing both inattention and hyperactivity/impulsivity. The relative efficacy of branded …

Network meta-analysis of probiotics, prebiotics, and synbiotics for the treatment of chronic constipation in adults

Probiotics Review

Constipation is a prevalent functional gastrointestinal disorder worldwide. According to the Rome III criteria for chronic constipation (CC) [ 1 ], nearly 16% of adults globally suffer from this condition [ 2 ]. Its hallmark features include …
Webinar | 08-11-2023 | 18:00 (CET)

Keynote webinar | Spotlight on diet and diabetes

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An expert-led symposium exploring the prevention and management of type 2 diabetes through dietary interventions. Highlights include discussion of the recent EASD guidelines, therapeutic diets, food types and processing, plus psychological factors that influence patient success, and the drivers of healthy eating and diabetes control.

Prof. Mike Lean
Prof. Falko Sniehotta
Developed by: Springer Medicine

CME & eLearning

Expert Interviews | Videos (Link opens in a new window)

Pediatric Obesity

With adolescent obesity at an all-time high, greater understanding of the individual cost and societal burden is crucial. Discover the unique challenges faced by adolescents with obesity, and learn effective strategies to help young people to overcome this disease.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

Diabetes

1.5 AMA PRA Category 1 Credit(s)™

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

eLearning | Interviews (Link opens in a new window)

Hemophilia

This independent educational program aims to highlight advances in the diagnosis, treatment, and management of patients with hemophilia that have the potential to improve patients’ outcomes and quality of life.

Supported by:
  • Sanofi
Developed by: Springer Healthcare IME

Case-Based Insights: Oncology and Hematology (Link opens in a new window)


Refresh your knowledge in Oncology and Hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now

Pediatrics journals

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Further Reading

Intracranial volumetric evaluation in postnatally repaired myelomeningocele infants

Open Access Hydrocephalus Research

The most severe form of open spina bifida (dysraphism), myelomeningocele (MMC) [ 1 ], accounts for 98.8% of open spina bifida [ 2 ]. Hydrocephalus poses a significant concern [ 3 ], with comorbidity rates in MMC rising from 10–15% at birth to …

Surgical management of lobar cerebral cavernous malformations in children: a single-center experience

Open Access Epilepsy Research

Cerebral cavernous malformations (CCMs), also known as cavernomas, are low-flow vascular lesions comprised of dilated sinusoidal thin-walled blood vessels without intervening brain parenchyma. The abnormal vessels forming CCMs lack a muscular …

CT findings as predictive factors for treatment failure in Mycobacterium abscessus complex lung disease: a retrospective cohort study

Open Access Computed Tomography Original Article

Non-tuberculous mycobacteria (NTM) are previously recognized as non-pathogenic environmental bacteria, and the clinical significance of their associated diseases was neglected until the mid-twentieth century. Methodological advances in the …

SAGES guidelines for the use of laparoscopy during pregnancy

Open Access Appendicitis SAGES/EAES Official Publication

The purpose of these guidelines is to provide evidence-based recommendations for the management of common surgical problems during pregnancy from a surgeon and patient perspective. We assessed surgical and obstetric outcomes after management of …

Related topics

Open Access Turner's Syndrome Review

Turner syndrome: improving the transition from pediatric to adult care

Multisystem involvement in Turner syndrome makes the transition from pediatric to adult care very challenging. Explore guidance on all aspects of transition and referral.

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Overnight bracing prevents curve progression in adolescent scoliosis

27-02-2024 Adolescent Idiopathic Scoliosis News

How does ECMO affect brain development?

Open Access Early Childhood Brain Injury Review

Safely transitioning patients in nephrology

Pediatric Nephrology Review

Chronic abdominal pain and constipation diagnosed as glycogen storage disease type IX

Open Access Metabolic Disease and Nutrition Case Study

Teratogenic risk low with second-line noninsulin antidiabetic agents

05-01-2024 Diabetes and Pregnancy News
26-04-2024 Whole Blood Values in Children News

An alternative to venous neonatal blood draw?

Umbilical cord blood could be a valid alternative to neonatal blood for measuring hemoglobin if a correction factor is applied.

Read more

Benefits of newborn screening for SMA

24-04-2024 Spinal Muscular Atrophy News

Potential micronutrient deficiencies in the first 1000 days of life

Open Access Basics of Nutrition in Children Review

Genetic causes of polyhydramnios

Open Access Polyhydramnions Case Study

How to recognise rare Kawasaki disease in neonates

Open Access Kawasaki Disease Case Study

How does ECMO affect brain development?

Open Access Early Childhood Brain Injury Review
Congenital Valvular Heart Disease Review

Insights into inherited valvular heart disease

What have we learned about the genetic causes of  valvular heart diseases in the last five years? This overview will bring you up to speed.

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Double trouble: dual outflow tract obstruction

Open Access Congenital Heart Anomaly Case Study

Bacterial endocarditis caused by contact lens use

Open Access Endocarditis Case Study

Implantable monitor for heart failure in DMD

Open Access Telemonitoring in Cardiology Case Study

How can we better manage high blood pressure in children?

Metabolic Disease in Childhood Review

Echogenomics in heritable aortopathies

Congenital Heart Anomaly Review
23-04-2024 Type 1 Diabetes News

Lower heritability of adult-onset versus childhood-onset type 1 diabetes

Type 1 diabetes that develops in adulthood has weaker familial associations than type 1 diabetes that develops in childhood.

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Practical tips for managing pediatric diabetes

Open Access Type 2 Diabetes in Children Guideline

Turner syndrome: improving the transition from pediatric to adult care

Open Access Turner's Syndrome Review

Echogenomics in heritable aortopathies

Congenital Heart Anomaly Review

Home insulin pump use feasible for hospitalized children with T1D

20-02-2024 Type 1 Diabetes in Children News

Promising treatment for Niemann–Pick disease type C

13-02-2024 Niemann-Pick Disease News
08-05-2024 Assisted Reproduction News

Embryo transfer may increase risk for childhood leukemia

A French cohort study has found a significantly increased risk for leukemia in children born after fresh or frozen embryo transfer versus those conceived naturally.

Read more

Skin atrophy after treatment of infantile hemangioma

Open Access Infantile Hemangioma Case Study

Special considerations for managing CML in children

Chronic Myeloid Leukemia Review

CNS tumors: what should the neonatologist know?

Open Access CNS Tumors in Pediatrics Review

Causes of chronic limping in childhood

Open Access Pediatric Rheumatology Case Study

Advances in pediatric medulloblastoma

Open Access Medulloblastoma Review
Post-COVID Syndrome Review

Treating multisystem inflammatory syndrome in children

MIS-C is a relatively uncommon but severe pediatric complication associated with COVID-19, requiring rapid and intensive treatment. What are the most effective treatment strategies?

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RSV vaccine during pregnancy may protect infants but increases prematurity risk

20-03-2024 Respiratory Syncytial Virus Infection News

The blue catheter

Disease of the Nervous System in Children Case Study

Viral DNAemia may predict sepsis-related mortality in children

08-03-2024 Septicemia News

Severe pediatric COVID-19

Open Access COVID-19 Review

New criteria to help identify children at risk for sepsis

14-02-2024 Septicemia News
Open Access Foreign Bodies in Esophagus and Bronchi Case Study

Chronic stridor in a toddler caused by a discharged battery

Ingested button batteries are usually charged and quickly cause severe symptoms, but ingesting a discharged battery is very rare. Unspecific symptoms can complicate and delay diagnosis, risking long-term complications.

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Oral corticosteroids reduce wheeze severity in preschoolers

11-04-2024 Respiratory Medicine News

Potential micronutrient deficiencies in the first 1000 days of life

Open Access Basics of Nutrition in Children Review

Airway pressure release ventilation for trauma-induced ARDS

Open Access Acute Respiratory Distress-Syndrome Case Study

Ibuprofen ineffective for patent ductus arteriosus

30-01-2024 Patent Ductus Arteriosus News

Nirsevimab alleviates hospital admissions due to RSV infection in infants

18-01-2024 Respiratory Syncytial Virus Infection News
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