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Pediatrics Pediatric Infectious Disease

Pediatric Infectious Disease

IL-6 shows promise as diagnostic biomarker for sepsis

Interleukin-6 shows promise as a biomarker to diagnose sepsis early in high-risk patient groups such as neonates, children, and pregnant women.

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Editor's Choice

Managing septic shock in a pediatric AML patient

A 10-year-old boy exhibited persistent pancytopenia following treatment for mucormycosis, with further diagnosis revealing AML. Septic shock soon followed, but was successfully managed with combined CRRT and CytoSorb therapy.

Sudden post-viral vision loss in children could be new clinical entity

Sudden severe bilateral vision loss in young children who have recently recovered from a febrile illness may be indicative of a new and potentially underrecognized clinical entity.

COVID-19 linked to long-term poor GI health in children

Children with COVID-19 have a heightened risk for gastrointestinal symptoms and disorders during the postacute and chronic phases.

Pertussis in children: expert consensus

Despite high vaccination rates in children, whooping cough has resurged in many developed countries. How can we better prevent, diagnose, and manage the disease?

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Case Studies

Managing septic shock in a pediatric AML patient

A 10-year-old boy exhibited persistent pancytopenia following treatment for mucormycosis, with further diagnosis revealing AML. Septic shock soon followed, but was successfully managed with combined CRRT and CytoSorb therapy.

Stevens–Johnson syndrome due to COVID-19 infection in a teenager

Stevens–Johnson syndrome is a life-threatening condition characterized by high fever and severe mucocutaneous lesions. Cases increased during the COVID-19 pandemic, but mostly in adults. What do we know about pediatric cases?

Vitamin D-dependent rickets complicated with RSV infection

Vitamin D-dependent rickets type 1 A causes failure to thrive, hypotonia, and increased fracture risk, and may complicate the clinical course of lower respiratory tract infections. How would you address the therapeutic challenges in this toddler?

Current Reviews

Vaccine-Preventable Diseases in Pediatric Age Group in India: Recent Resurgence, Implications and Solutions

This review examines the recent increase and the changing epidemiology of vaccine-preventable diseases (VPDs) in pediatric age group in India, explores the current challenges, and outlines strategies to restore and sustain vaccination coverage …

Vaccination in Pediatric Office Practice: Everyday Challenges and Practical Solutions

Vaccination is a vital component of pediatric healthcare, safeguarding children from numerous preventable diseases. In India, the ‘Universal Immunisation Programme’ and ‘Intensified Mission Indradhanush’ offer free vaccinations to protect against …

Pathogenic characterization and drug resistance of neonatal sepsis in China: a systematic review and meta-analysis

Neonatal sepsis (NS) refers to a systemic inflammatory response syndrome in the neonatal period in which pathogenic bacteria are cultured from sterile cavities, such as blood or cerebrospinal fluid, in which bacteria are the main pathogens of NS [ …

Autopsy-related histomorphological findings in neonatal sepsis: a narrative review

Neonatal sepsis is an important concern in the field of neonatology, contributing significantly to morbidity and mortality among newborns worldwide. Despite progress in medical care, the accurate diagnosis and comprehension of the pathological …

Further Reading

Predictors and outcomes of premature rupture of membranes among pregnant women admitted to a teaching Hospital in Saudi Arabia: a cohort study

Premature rupture of membranes (PROM) is a critical obstetric condition affecting approximately 5–10% of all pregnancies, with significant implications for maternal and neonatal health [ 1 – 3 ]. Preterm premature rupture of membranes (PPROM) …

Cost of integrated immunization campaigns in Nigeria and Sierra Leone: bottom-up costing studies

Immunization campaigns have historically been a very effective tool to prevent or react to a disease outbreak, to rapidly achieve herd immunity when introducing a new vaccine in the routine program, and to target specific areas or population …

Congenital cytomegalovirus infection in newborns suspected of congenital rubella syndrome in Iran: a cross-sectional study

Human cytomegalovirus (HCMV) is a host-restricted member in the β herpesvirinae subfamily of the Herpesviridae family [ 1 ]. Like other herpes viruses after primary infection, the virus remains latent. The rate of seroprevalence in adults is around …

Adverse pregnancy outcomes and multiple cancers risk in both mother and offspring: an umbrella review of systematic reviews with meta-analyses of observational studies

  • Open Access
  • Leukemia
  • Original Research

Although maternal deaths have decreased globally by 38% in the last two decades, the occurrence of adverse pregnancy outcomes has been seen with an increasing trend [ 1 – 3 ]. For instance, worldwide incidence of hypertensive disorders of pregnancy …