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CNS Tumors in Pediatrics 

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  1. Open Access 11-01-2024 | CNS Tumors in Pediatrics | ReviewPaper

    Central nervous system tumours in neonates: what should the neonatologist know?

    CNS tumors are relatively rare in neonates and present differently than those occurring later in childhood in terms of etiology, clinical features, location, histology, and prognosis. How can neonatologists ensure early diagnosis and optimum treatment?

  2. Open Access 07-09-2023 | Pediatric Cancer | Case Study

    ​Occult extracranial malignancy after complete remission of pineal mixed germ cell tumors: a rare case report and literature review

    Primary intracranial germ cell tumors (GCTs) may disseminate to the ventricular system or subarachnoid space of the spinal cord [ 1 ], however, their

  3. Open Access 09-11-2023 | Medulloblastoma | Review

    Recent Advances in Pediatric Medulloblastoma

    Medulloblastomas are the most common malignant brain tumors in children. Advances in understanding their etiology, biology, radiology, and management are discussed.

  4. 25-04-2024 | Glioma | Online First

    Role of sodium fluorescein in pediatric low-grade glioma surgery: an update

    Tumors of the central nervous system (CNS) represent the most common solid neoplasms in the pediatric age [ 44 ]. An important percentage of these lesions is constituted by low-grade gliomas (LGG) and low-grade glioneuronal (LGGn) tumors. These are …

  5. 01-04-2024 | Events

    SPR 2024

  6. 12-04-2024 | Glioma | Online First

    Pediatric hemispheric cerebellar low-grade gliomas: clinical approach, diagnosis, and management challenges—experience at a tertiary care children’s hospital

    Pediatric low-grade gliomas (pLGGs) represent a significant subset of central nervous system neoplasms in children, comprising over 30% of all pediatric brain tumors [ 1 ]. These tumors are predominantly characterized by their slow growth and …

  7. 03-05-2024 | Glioma | Online First

    The role of focused ultrasound for pediatric brain tumors: current insights and future implications on treatment strategies

  8. 17-04-2024 | Glioma | Online First

    Bibliometric analysis of emerging trends and research foci in brainstem tumor field over 30 years (1992–2023)

    Brainstem tumors constitute a heterogeneous group, predominantly affecting pediatric populations [ 1 ]. The majority of these tumors display diffuse growth without distinct boundaries in imaging examinations, with over 80% being classified as …

  9. Open Access 01-12-2024 | Acute Lymphoblastic Leukemia | OriginalPaper

    Intracranial residual lesions following early intensification in a patient with T-cell acute lymphoblastic leukemia: a case report

    Leukemia is the most common cancer in children and the involvement of the central nervous system (CNS) increases the risk of CNS relapse [ 1 ]. Risk factors of CNS leukemia include infant onset, T-cell acute lymphoblastic leukemia (T-ALL) …

  10. 20-04-2024 | Computed Tomography | Online First

    Central nervous system embryonal tumor with PLAGL1 amplification: a case report of a novel entity focusing on imaging findings

    The embryonal central nervous system (CNS) tumor with PLAGL1 (pleomorphic adenoma gene-like) amplification is a novel type of pediatric neoplasm with a distinct methylation profile, described for the first time in 2022. It may be located anywhere …

  11. Open Access 01-12-2024 | Brain Tumor | OriginalPaper

    Histological types of brain tumors diagnosed at the Kenyatta National Hospital between 2016 and 2019: a retrospective study

    Globally, in 2020, approximately 19.3 million new cancers and 10 million deaths from cancer were reported. Of these, brain tumors (BTs) constituted approximately 308,102 (1.6%) new cases and 251,329 (2.5%) deaths [ 1 ]. The prevalence of BTs varies …

  12. 15-04-2024 | Brain Tumor | Online First

    Clinical factors, management, and outcomes of children under 3 years old with central nervous system tumors: single-center experience

    Central nervous system (CNS) tumors remain the most prevalent malignant solid tumors in childhood, accounting for 16–25% of all tumor cases [ 1 ]. Treatment typically involves a multidisciplinary approach, with surgery, radiotherapy, and …

  13. 22-04-2024 | Glioma | Online First

    Cylinder tumor surgery in pediatric low-grade gliomas

    Central nervous system (CNS) tumors are the most frequent solid tumors in children, making CNS tumors the leading cause of cancer-related death in children. Beyond CNS tumors, pediatric-type low-grade gliomas (pLGG) are the most frequent childhood …

  14. Open Access 08-04-2024 | Bevacizumab | Online First

    Distribution of Bevacizumab into the Cerebrospinal Fluid of Children and Adolescents with Recurrent Brain Tumors

    Brain tumors represent the most common form of solid malignancies in the pediatric population and substantially contribute to cancer-related morbidity and mortality in children and adolescents [ 1 ]. Despite multimodal treatment strategies …

  15. Open Access 27-04-2024 | Glioma | Online First

    How modern treatments have modified the role of surgery in pediatric low-grade glioma

    Low-grade gliomas are the most common brain tumor of childhood, and complete resection offers a high likelihood of cure. However, in many instances, tumors may not be surgically accessible without substantial morbidity, particularly in regard to …

  16. 19-04-2024 | Retinoblastoma | Online First

    Management of Extraocular Retinoblastoma: ICMR Consensus Guidelines

    Retinoblastoma (RB) is the most common intraocular malignancy of childhood. Advanced stage presentation of RB is common in low middle-income countries (LMICs) due to lack of awareness, social taboos associated with enucleation, seeking alternative …

  17. 03-04-2024 | Neuromonitoring | Online First

    Multidisciplinary Consensus on Curricular Priorities for Pediatric Neurocritical Care Nursing Education: A Modified Delphi Study in the United States

    The field of pediatric neurocritical care (PNCC) is a distinct specialty that requires integrating knowledge of pediatric health care systems, childhood neurological and neurosurgical diseases, and developmental central nervous system (CNS) …

  18. 22-04-2024 | Hamartoma | Online First

    Imaging findings of children with PTEN-related hamartoma tumor syndrome: a 20-year multicentric pediatric cohort

    Germline pathogenic variants in the phosphatase and tensin homolog (PTEN) gene are associated with PTEN hamartoma tumor syndrome, which includes a broad spectrum of autosomal dominant clinical phenotypes with overlapping features [ 1 ]. The …

  19. Open Access 01-12-2023 | Hydrocephalus | Abstract

    Abstracts from Hydrocephalus 2023—the fifteenth meeting of the Hydrocephalus Society

  20. 07-02-2024 | Intramedullary Space-Occupying Lesion | OriginalPaper

    Intramedullary spinal cord tumors in pediatric patients presenting later with brain lesions: case series and systematic review of the literature

    Intramedullary spinal cord tumors (IMSCT) are an uncommon pathology in adults and children. While intramedullary tumors are more common in children than adults, they account for less than 30% of all spinal cord tumor cases in the pediatric …

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