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Type 1 Diabetes 

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  1. 25-04-2024 | Type 1 Diabetes | Online First

    Vitamin D efficacy in type 1 and type 2 diabetes

    It is well known that vitamin D has a profound effect on calcium and bone metabolism, but its influence on other organs (extraskeletal effect) has been proposed. Consistently, vitamin D deficiency is associated with an increased incidence of …

  2. Open Access 20-02-2024 | Hypoglycemia | OriginalPaper

    Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study

    Despite a century of development and refinement of insulin therapy, hypoglycaemia remains the most common complication, affecting virtually all people with type 1 diabetes and most of those with insulin-treated type 2 diabetes [ 1 ]. Thus, people …

  3. Open Access 01-12-2024 | Type 2 Diabetes | OriginalPaper

    Perceptions of diabetes distress during pregnancy in women with type 1 and type 2 diabetes: a qualitative interpretive description study

    For women with pre-existing diabetes who become pregnant, diabetes management will be at the center of their pregnancy journey. Pre-existing diabetes is type 1 diabetes (T1D) or type 2 diabetes (T2D) that is present before pregnancy and pregnancy …

  4. Open Access 01-12-2024 | Insulins | OriginalPaper

    Understanding suboptimal insulin use in type 1 and 2 diabetes: a cross-sectional survey of healthcare providers who treat people with diabetes

    Achieving optimal glycemic outcomes is critical for effective management of diabetes, and basal-bolus treatment regimens are currently seen as the standard of care for insulin injection therapy for fasting and post-prandial glucose in people with …

  5. 17-04-2024 | Diabetes | Online First

    The health-related quality of life of patients with type 1 and type 2 diabetes mellitus: a meta-analysis

    Diabetes Mellitus (DM) poses a significant and persistent chronic health challenge, driven by its escalating prevalence, substantial disease burden, and the associated financial and societal complexities [ 1 , 2 ]. The rising prevalence of DM can …

  6. 23-04-2024 | Type 1 Diabetes | News | Article

    Lower heritability of adult-onset versus childhood-onset type 1 diabetes

    Type 1 diabetes that develops in adulthood has weaker familial associations than type 1 diabetes that develops in childhood.

  7. Open Access 01-12-2024 | Type 2 Diabetes | OriginalPaper

    Lipidome characterisation and sex-specific differences in type 1 and type 2 diabetes mellitus

    Diabetes mellitus (DM) is characterized by chronic hyperglycaemia that leads to heterogenous disturbances of metabolism [ 1 ] and its continuing rise is a major concern in society [ 2 ]. DM is one of the main risk factors for cardiovascular disease …

  8. Open Access 01-12-2024 | Stroke | OriginalPaper

    Stroke incidence increases with diabetic retinopathy severity and macular edema in type 1 diabetes

    Type 1 diabetes is associated with a three- to sixfold risk of stroke [ 1 – 3 ]. In the general population, including individuals with diabetes, an array of retinal vascular abnormalities have been associated with increased stroke risk [ 4 ]. Less …

  9. 19-03-2024 | Type 1 Diabetes | Online First

    Associations between daily step count classifications and continuous glucose monitoring metrics in adults with type 1 diabetes: analysis of the Type 1 Diabetes Exercise Initiative (T1DEXI) cohort

    Achieving the guidelines of 150 minutes of moderate to vigorous physical activity per week is associated with maintenance of whole-body insulin sensitivity, lower total daily insulin needs, improved cardiovascular health and weight maintenance in …

  10. Open Access 01-12-2024 | Idiopathic Pulmonary Fibrosis | OriginalPaper

    Mendelian randomisation highlights type 1 diabetes as a causal determinant of idiopathic pulmonary fibrosis

    IPF is an incurable and worsening respiratory condition of unknown cause, characterized by the progressive deterioration of lung function. The median life expectancy for individuals with IPF is a mere 3.8 years [ 1 , 2 ]. The progression of disease …

  11. Open Access 20-04-2024 | Type 1 Diabetes | Online First

    Effects of Two COVID-19 Lockdowns on HbA1c Levels in Patients with Type 1 Diabetes and Associations with Digital Treatment, Health Literacy, and Diabetes Self-Management: A Multicenter, Observational Cohort Study Over 3 Years

    During the recent coronavirus disease 2019 (COVID-19) pandemic, nationwide lockdowns were imposed in most countries to contain the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [ 1 – 4 ]. Patients with diabetes mellitus …

  12. 07-03-2024 | Insulins | Online First

    Correction: New diagnostic criteria (2023) for slowly progressive type 1 diabetes (SPIDDM): Report from Committee on Type 1 Diabetes in Japan Diabetes Society (English version)

  13. Open Access 25-04-2024 | Type 1 Diabetes | Online First

    The metabolome as a diagnostic for maximal aerobic capacity during exercise in type 1 diabetes

    Exercise provides health benefits for individuals with type 1 diabetes, through reducing CVD, improving skeletal muscle health and increasing fitness [ 1 , 2 ]. Despite the benefits of exercise, barriers to its use as a diabetes therapy remain.

  14. Open Access 25-04-2024 | Type 1 Diabetes | Online First

    The psychosocial outcomes of advanced hybrid closed-loop system in children and adolescents with type 1 diabetes

    The study was carried out to determine the psychosocial outcomes of advanced hybrid closed-loop (AHCL) systems in children and adolescents with type 1 diabetes (T1D). Single-center and cohort study with a duration 6 months consisted of 60 children …

  15. Open Access 03-04-2024 | Microalbuminuria | Online First

    Serum carnosinase 1, an early indicator for incident microalbuminuria in type 1 diabetes

    Carnosinase (CN1) is a serum enzyme degrading histidine-containing dipeptides, i.e. carnosine, anserine and homocarnosine. Because of the beneficial properties of these dipeptides including anti-oxidative effects, increased serum CN1 …

  16. Open Access 30-01-2024 | Type 1 Diabetes | OriginalPaper

    Association Between Adherence, A1C Improvement, and Type of Continuous Glucose Monitoring System in People with Type 1 Diabetes or Type 2 Diabetes Treated with Intensive Insulin Therapy

    Continuous glucose monitoring (CGM) systems are increasingly used by people with type 1 diabetes (T1D) or type 2 diabetes using intensive insulin therapy (T2D-IIT). There are two types of CGM systems—real-time (rtCGM) and intermittently scanned …

  17. 21-02-2024 | Type 1 Diabetes | OriginalPaper

    Use of teplizumab in children and adolescents at risk of type 1 diabetes: perspectives of parents and caregivers from an Italian Pediatric Diabetes Center

    Type 1 diabetes (T1D) is an autoimmune disease characterized by the progressive T cell-mediated destruction of pancreatic beta cells, resulting in absolute insulin deficiency, derangement of glucose metabolism, and the need for insulin replacement …

  18. 19-04-2024 | Hypoglycemia | Online First

    Beyond HbA1c: Identifying Gaps in Glycemic Control Among Children and Young People with Type 1 Diabetes Using Continuous Glucose Monitoring

    Type 1 diabetes is a chronic disease leading to long-term complications. Based on the results from the DCCT study, modern-day insulin regimens aim to achieve normoglycemia to minimize risk of long-term complications [ 1 ]. Glycosylated hemoglobin …

  19. Open Access 01-12-2024 | Type 2 Diabetes | OriginalPaper

    The efficacy and safety of GLP-1 receptor agonists in youth with type 2 diabetes: a meta-analysis

    In 2021, an estimated 41,600 new cases of youth-onset type 2 diabetes emerged worldwide [ 1 ]. By 2017, among 1,848,899 youths aged 10–19 years in the United States, 1,230 children were diagnosed with type 2 diabetes mellitus (T2DM) [ 2 ]. The …

  20. 14-03-2024 | Type 1 Diabetes | Online First

    Shared and distinct genetics of pure type 1 diabetes and type 1 diabetes with celiac disease, homology in their auto-antigens and immune dysregulation states: a study from North India

    India accounts for most of the children with Type 1 diabetes (T1D) in South-East Asia [ 1 ]. A remarkably high prevalence of celiac disease (CD) among T1D is also seen in India, ranging from 11 to 13.5% [ 2 , 3 ] compared to the diabetic European …

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