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Type 2 Diabetes in Children 

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  1. Open Access 02-04-2024 | Type 2 Diabetes in Children | Guideline

    A practical evidence-based approach to management of type 2 diabetes in children and young people (CYP): UK consensus

    This UK consensus guideline provides a practical approach to the assessment and management of type 2 diabetes and associated complications in children and young people.

  2. Open Access 01-12-2024 | COVID-19 | OriginalPaper

    Characterization of newly diagnosed type 1 diabetes in children and adolescents from 2017 to 2022 in China: a single-center analysis

    Type 1 diabetes mellitus (T1DM) is the most common type of diabetes in children and adolescents [ 1 ]. In most cases, it is caused by the autoimmune destruction of pancreatic β-cells resulting in insulin deficiency and hyperglycaemia [ 2 ]. T1DM is …

  3. 14-08-2023 | COVID-19 | OriginalPaper

    Incidence of type 1 diabetes in Chilean children between 2006 and 2021: significant increase during the COVID-19 pandemic

    T1D is characterized by chronic immune-mediated destruction of pancreatic β cells, leading to partial, or in most cases, absolute insulin deficiency. It is the most common form of diabetes in children and adolescents, accounting for more than 90% …

  4. Open Access 16-08-2023 | COVID-19 | ReviewPaper

    SARS-CoV-2 vaccination in children and adolescents with and without type 1 diabetes mellitus

    Adults with Diabetes Mellitus (DM) have increased risk of severe clinical presentation during COVID-19 infection, while children and adolescents with type 1 diabetes (T1D) have the same mild clinical course as their healthy peers, especially those …

  5. 04-07-2023 | Albuminuria | OriginalPaper

    Plasma leucine-rich α-2-glycoprotein 1 – a novel marker of diabetic kidney disease in children and adolescents with type 1 diabetes mellitus?

    Diabetic kidney disease (DKD) is one of the common complications of diabetes and the leading cause of kidney failure [ 1 ]. Although advanced stages of nephropathy such as stage 5 chronic kidney disease are rare in children and adolescents with …

  6. Open Access 01-12-2022 | Celiac Disease | OriginalPaper

    Prevalence of haplotype DQ2/DQ8 and celiac disease in children with type 1 diabetes

    Type 1 diabetes (T1D) and celiac disease (CD) coexist very often. Identification of the human leukocyte antigen (HLA) DQ2/DQ8 can confirm the genetic predisposition to CD. Negative result of this test allows to exclude CD with a high probability.

  7. 27-08-2022 | Obesity | ReviewPaper

    Type 2 diabetes in children and adolescents: distinct characteristics and evidence-based management

    Type 2 diabetes (T2D), the most common type of diabetes among adults globally, is characterized by insulin resistance and insufficiency. Although T2D is relatively rare among children and adolescents in Europe, it has become an emerging pediatric …

  8. 07-10-2022 | Type 1 Diabetes | OriginalPaper

    Age-period-cohort modelling of type 1 diabetes incidence rates among children included in the EURODIAB 25-year follow-up study

    Type 1 diabetes is an autoimmune disease in which the insulin producing cells of the pancreas are attacked and destroyed leading to insulin deficit. Type 1 diabetes is often diagnosed during childhood and the incidence has been increasing in both …

  9. Open Access 01-12-2022 | Obesity | OriginalPaper

    Changes from 1986 to 2018 in the prevalence of obesity and overweight, metabolic control and treatment in children with type 1 diabetes mellitus in a Mediterranean area of Southeast Spain

    A global increase in the prevalence of childhood overweight and obesity has been noted in the last few decades [ 1 ], with a tendency toward stabilization in recent population studies [ 2 , 3 ]. Similarly, the incidence and prevalence of type 1 …

  10. 01-07-2023 | OriginalPaper

    USPSTF and ISPAD Guidelines on Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents

    The rising trends of obesity, metabolic syndrome and diabetes in adults are worrisome globally. The majority of antecedents to adult non-communicable diseases begin in childhood. Type 2 diabetes is recognized as one of the major diseases that …

  11. Open Access 01-12-2021 | Type 1 Diabetes in Children | OriginalPaper

    Type 1 diabetes in 2017: global estimates of incident and prevalent cases in children and adults

    Diabetes is one of the four non-communicable diseases (NCDs) prioritised by the WHO [ 1 ]. Although diabetes encompasses both type 1 and type 2 diabetes, type 2 diabetes is given more attention due to its shared risk factors with other NCDs and its …

  12. 01-12-2021 | Obesity | Original Research

    Investigation of the levels of circulating miR-29a, miR-122, sestrin 2 and inflammatory markers in obese children with/without type 2 diabetes: a case control study

    Globally, the prevalence of childhood and adolescence obesity has increased markedly in the last decade [ 1 , 2 ]. About 30% of Saudi Arabia children were reported to be obese or overweight [ 3 , 4 ]. Obese children have a high risk of developing …

  13. 01-12-2021 | Obesity

    Effectiveness and process evaluation in obesity and type 2 diabetes prevention programs in children: a systematic review and meta-analysis

    Obesity has important effects on health in the short, medium and long terms where metabolic complications are common [ 1 ]. In children, overweight and obesity’s prevalence has increased in every continent of the world in recent decades [ 2 ].

  14. 01-09-2021 | COVID-19 | OriginalPaper

    Impact of COVID-19 lockdown on glycaemic control and lifestyle changes in children and adolescents with type 1 and type 2 diabetes mellitus

    The catastrophic outbreak of novel severe acute respiratory syndrome coronavirus 2 in Wuhan City, China in December 2019, has spread globally within months and was declared a pandemic since March 2020 by the World Health Organization. At the time …

  15. 01-07-2021 | Type 1 Diabetes | OriginalPaper

    Type 1 diabetes in children: a scientometric assessment of Indian research output from 1990 to 2019

    Type 1 diabetes (T1D) is the most common endocrine disease in children with an increasing global incidence of 3–5% per year. India is witnessing a consistent increase in the incidence of T1D over the past several years along with Finland, Sweden …

  16. Open Access 01-12-2021 | Diabetes Prevention | OriginalPaper

    Rationale and design of a type 2 diabetes prevention intervention for at-risk mothers and children at a Federally Qualified Healthcare Center: EPIC El Rio Families Study Protocol

    Type 2 diabetes (T2DM) continues to be a major public health problem in the United States, with over 30 million persons afflicted and estimates projecting a continued increase [ 1 , 2 ]. Youth comprise a small yet growing number of new T2DM cases …

  17. Open Access 01-09-2020 | Infertility | OriginalPaper

    Live-born children after assisted reproduction in women with type 1 diabetes and type 2 diabetes: a nationwide cohort study

    Type 1 and type 2 diabetes are among the most prevalent chronic diseases in women in their fertile years [ 1 ]. The state of autoimmunity is well known in type 1 diabetes [ 2 , 3 ], and women with type 1 diabetes may experience several reproductive …

  18. Open Access 01-12-2021 | Hypoglycemia | OriginalPaper

    A comparison of FreeStyle Libre 2 to self-monitoring of blood glucose in children with type 1 diabetes and sub-optimal glycaemic control: a 12-week randomised controlled trial protocol

    In New Zealand, there are an estimated 2,500 youth aged 0–18 years living with type 1 diabetes [ 1 – 3 ]. New Zealand has one of the highest rates of paediatric diabetes in the world, with the incidence growing annually [ 4 ]. Internationally, only …

  19. 01-10-2020 | Obesity | ReviewPaper

    Cognitive Behavioral Therapy and Mindfulness-Based Cognitive Therapy in Children and Adolescents with Type 2 Diabetes

    Type 2 diabetes (T2D) in children and adolescents is a serious health problem, with increasing prevalence in most regions of the world [ 1 ]. Earlier onset of T2D is associated with high prevalence of early complications [ 2 ]. Poor adherence to …

  20. 01-12-2020 | Insulins | OriginalPaper

    Plasma circulating miR-23~27~24 clusters correlate with the immunometabolic derangement and predict C-peptide loss in children with type 1 diabetes

    Type 1 diabetes is one of the most common chronic autoimmune diseases of childhood in which cells of the innate and adaptive immune system invade the pancreatic islets causing inflammation, beta cell destruction and progressive loss of insulin …

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